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The map label for this gene is fabG [H]

Identifier: 89054768

GI number: 89054768

Start: 2283967

End: 2284746

Strand: Direct

Name: fabG [H]

Synonym: Jann_2277

Alternate gene names: 89054768

Gene position: 2283967-2284746 (Clockwise)

Preceding gene: 89054767

Following gene: 89054769

Centisome position: 52.89

GC content: 62.31

Gene sequence:

>780_bases
GTGGATCTGGGAATTGCAGGGCGCAAGGCGATCGTCTGCGGATCATCACGCGGCCTTGGGCGCGCCTGCGCCGAGGCGTT
GCTGCGCGAAGGCGCGGAGGTTGTACTCAACGGGCGTGACGCACACGCATTGGACGTCTTGTCAGATGAACTGTCGCGGC
AAACCGGCCAGAAAGCCACGGCCGTAGCCGCTGATCTGAACACCGAAGACGGGCGTGAGCGCCTTTTGGCCGCCTGTCCG
GCTCCGGACATTCTTGTGAACAACAACGGCGGACCGCCCTTCAAGGACTTCCGCGATCTGGATCGAGCCGCGATGGAGCG
GGGTGTGGCCATGAACATGCTGACCCCCATCGAATTGATCCAGCGCGTGATCGATGGCATGGCGGCGCGCGGCTTTGGCC
GCATCGTCAATATCACCTCAATCTCGGTCAAAATGCCGGTCTCTGGCCTCGATCTGTCCAGCGGCGCGCGGGCGGGTCTG
ACGGCGTTTTTGGCAGGCGTTGCGCGCGACTACGCAAACCAGGGCGTCACGATCAACCAACTTCTGCCCGGCTACTTTCT
GACCGAGCGCTTGCAGGAAGGCTTCAATGCCCAGGCCAGTCAAACTGGCGCAGCCCCGGCCGATGTGGCGCAAAGCTGGA
CCGATCAAGTGCCCGCTGCCCGTCTTGGCGACCCATTCGAGTTCGGCCAAACCTGTGCCTACCTTTGCGGCACGCAAGCG
GGCTACATCACCGGGCAGAACATCCTGATGGATGGCGGACTCTATAGAAGCGCTTTCTAA

Upstream 100 bases:

>100_bases
ACAGACCGCCGCCATTTCAAGACATTGCCGTTTATCTTCGATCCGGCTGTTGCCGTCGGTTAGCGCACGTTGGTGTTGTC
ACGCGAGAAGGAGAGCGCAC

Downstream 100 bases:

>100_bases
ATGCGGCCCCCGAGTTACGGCTATGGCCGGTTGCACATGTGCCGCTTACGGCCATGCGTTTTCAGGTTAATTTTCATTGA
GTTAACGCGCGAAAACAGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGIAGRKAIVCGSSRGLGRACAEALLREGAEVVLNGRDAHALDVLSDELSRQTGQKATAVAADLNTEDGRERLLAACP
APDILVNNNGGPPFKDFRDLDRAAMERGVAMNMLTPIELIQRVIDGMAARGFGRIVNITSISVKMPVSGLDLSSGARAGL
TAFLAGVARDYANQGVTINQLLPGYFLTERLQEGFNAQASQTGAAPADVAQSWTDQVPAARLGDPFEFGQTCAYLCGTQA
GYITGQNILMDGGLYRSAF

Sequences:

>Translated_259_residues
MDLGIAGRKAIVCGSSRGLGRACAEALLREGAEVVLNGRDAHALDVLSDELSRQTGQKATAVAADLNTEDGRERLLAACP
APDILVNNNGGPPFKDFRDLDRAAMERGVAMNMLTPIELIQRVIDGMAARGFGRIVNITSISVKMPVSGLDLSSGARAGL
TAFLAGVARDYANQGVTINQLLPGYFLTERLQEGFNAQASQTGAAPADVAQSWTDQVPAARLGDPFEFGQTCAYLCGTQA
GYITGQNILMDGGLYRSAF
>Mature_259_residues
MDLGIAGRKAIVCGSSRGLGRACAEALLREGAEVVLNGRDAHALDVLSDELSRQTGQKATAVAADLNTEDGRERLLAACP
APDILVNNNGGPPFKDFRDLDRAAMERGVAMNMLTPIELIQRVIDGMAARGFGRIVNITSISVKMPVSGLDLSSGARAGL
TAFLAGVARDYANQGVTINQLLPGYFLTERLQEGFNAQASQTGAAPADVAQSWTDQVPAARLGDPFEFGQTCAYLCGTQA
GYITGQNILMDGGLYRSAF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=31.25, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=25.5905511811024, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=25, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=25.2830188679245, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226371731, Length=189, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=25.1937984496124, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=23.7154150197628, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI20149619, Length=214, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=30.5220883534137, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=24.6153846153846, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=24.5210727969349, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=25.296442687747, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=27.1653543307087, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=23.3962264150943, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=28.8888888888889, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=25.78125, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=31.2267657992565, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.7878787878788, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=27.9850746268657, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.0536398467433, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=26.7924528301887, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=27.6264591439689, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=30.3370786516854, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=276, Percent_Identity=29.3478260869565, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=27.1317829457364, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.8625954198473, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=26.7441860465116, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.9693486590038, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=23.5294117647059, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=27.7153558052434, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.8426966292135, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=25.2918287937743, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24639444, Length=268, Percent_Identity=26.4925373134328, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=29.6577946768061, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=26.2948207171315, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=23.921568627451, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=24.031007751938, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=24.9027237354086, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27266; Mature: 27266

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIAGRKAIVCGSSRGLGRACAEALLREGAEVVLNGRDAHALDVLSDELSRQTGQKAT
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHHH
AVAADLNTEDGRERLLAACPAPDILVNNNGGPPFKDFRDLDRAAMERGVAMNMLTPIELI
HEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHH
QRVIDGMAARGFGRIVNITSISVKMPVSGLDLSSGARAGLTAFLAGVARDYANQGVTINQ
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEHHH
LLPGYFLTERLQEGFNAQASQTGAAPADVAQSWTDQVPAARLGDPFEFGQTCAYLCGTQA
HCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCC
GYITGQNILMDGGLYRSAF
CEEECCCEEECCCCHHCCC
>Mature Secondary Structure
MDLGIAGRKAIVCGSSRGLGRACAEALLREGAEVVLNGRDAHALDVLSDELSRQTGQKAT
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHHH
AVAADLNTEDGRERLLAACPAPDILVNNNGGPPFKDFRDLDRAAMERGVAMNMLTPIELI
HEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHH
QRVIDGMAARGFGRIVNITSISVKMPVSGLDLSSGARAGLTAFLAGVARDYANQGVTINQ
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEHHH
LLPGYFLTERLQEGFNAQASQTGAAPADVAQSWTDQVPAARLGDPFEFGQTCAYLCGTQA
HCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCC
GYITGQNILMDGGLYRSAF
CEEECCCEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]