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The map label for this gene is kynB [H]

Identifier: 89054240

GI number: 89054240

Start: 1738815

End: 1739633

Strand: Direct

Name: kynB [H]

Synonym: Jann_1749

Alternate gene names: 89054240

Gene position: 1738815-1739633 (Clockwise)

Preceding gene: 89054239

Following gene: 89054241

Centisome position: 40.27

GC content: 64.59

Gene sequence:

>819_bases
ATGTGTGATATTTGCGTGATGAATTCAGTGAAGGAGCGGATGCTGTCGCGGCGGTCGCTGTTCAAGGGCGGCTTGGCGGC
TGCGGGGGCGGCGGCCGTCGGCAGCACGTTCACCAAGGCCACCCCGGCGCTGGCGGATGGCCATGCGGGCGTGTTCGACA
TGACCCACACATTGTCCGAGGACTTCCCCACCTATTTCGGAGAGCCGGGGTTTAGCGCGGAGCAGGTGTTCAACTTCGCC
GATAACGGCTTCAACCTGTTCAATCTTTCGGTGAATGAGCATACCGGCACCCACATCGACGCGCCTCTGCATTTCAGCGC
CGATGGCACGTCTGTGGACGAGATCCCCGTGGGCGATCTGGTGGCACCGCTCTGCGTGATCGACATTGCCGCGCGCGCCG
AGGATGACGCCGATACGACCGTCACGCCCGATGATCTGCAAGCCTGGATCGATGCCAATGGCGAGATCCCCGATGGCGCT
TGCGTGGCGATGCATTCGGGGTGGGCCGCCAAGGTTGGGGGGGACGGGTTCCGTAACTTCGACGGCACCGCGCAGCATTA
TCCGGGCTTCCATATCGAGGCCACGCAGATGCTGCTGGAGACCGGCGCGCGGTCCATGGCGGTCGATACGCTGTCGCTCG
ATCACGGGATTTCCGCCGATTTCGCAACGCATTACGCGTGGTTGCCAAGCGGGCGCTTCGGGATCGAGAACCTCGCGGGT
CTGGACCAGGTGCCCGCCTCCGGGGCGACGCTGATCATCGGCGCGCCCAAGCATCGCGGCGGCACCGGCGGTCCGGCCCG
CATCTTCGCGATGGTGTGA

Upstream 100 bases:

>100_bases
GCGCCTGACCGAGCAGCGCACGCGCGATCTGGAATTGTACATGCGGCCCTGAGGCGTGTCGCGACGAAAGAGACAGAATT
CTAAGAGGAGGAGAAAAAAG

Downstream 100 bases:

>100_bases
CGTGGGAACGGTTGCTTTACTAAGTGACGAGGAGGTCAGCGCCGAGGCGCTGGCCGTCTTCAACGACATCCGCGCAGTGC
GGGGGACAGACTACGTCAAC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MCDICVMNSVKERMLSRRSLFKGGLAAAGAAAVGSTFTKATPALADGHAGVFDMTHTLSEDFPTYFGEPGFSAEQVFNFA
DNGFNLFNLSVNEHTGTHIDAPLHFSADGTSVDEIPVGDLVAPLCVIDIAARAEDDADTTVTPDDLQAWIDANGEIPDGA
CVAMHSGWAAKVGGDGFRNFDGTAQHYPGFHIEATQMLLETGARSMAVDTLSLDHGISADFATHYAWLPSGRFGIENLAG
LDQVPASGATLIIGAPKHRGGTGGPARIFAMV

Sequences:

>Translated_272_residues
MCDICVMNSVKERMLSRRSLFKGGLAAAGAAAVGSTFTKATPALADGHAGVFDMTHTLSEDFPTYFGEPGFSAEQVFNFA
DNGFNLFNLSVNEHTGTHIDAPLHFSADGTSVDEIPVGDLVAPLCVIDIAARAEDDADTTVTPDDLQAWIDANGEIPDGA
CVAMHSGWAAKVGGDGFRNFDGTAQHYPGFHIEATQMLLETGARSMAVDTLSLDHGISADFATHYAWLPSGRFGIENLAG
LDQVPASGATLIIGAPKHRGGTGGPARIFAMV
>Mature_272_residues
MCDICVMNSVKERMLSRRSLFKGGLAAAGAAAVGSTFTKATPALADGHAGVFDMTHTLSEDFPTYFGEPGFSAEQVFNFA
DNGFNLFNLSVNEHTGTHIDAPLHFSADGTSVDEIPVGDLVAPLCVIDIAARAEDDADTTVTPDDLQAWIDANGEIPDGA
CVAMHSGWAAKVGGDGFRNFDGTAQHYPGFHIEATQMLLETGARSMAVDTLSLDHGISADFATHYAWLPSGRFGIENLAG
LDQVPASGATLIIGAPKHRGGTGGPARIFAMV

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 28487; Mature: 28487

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDICVMNSVKERMLSRRSLFKGGLAAAGAAAVGSTFTKATPALADGHAGVFDMTHTLSE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHH
DFPTYFGEPGFSAEQVFNFADNGFNLFNLSVNEHTGTHIDAPLHFSADGTSVDEIPVGDL
HCHHHCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCEECCCEEECCCCCCCCCCCCHHH
VAPLCVIDIAARAEDDADTTVTPDDLQAWIDANGEIPDGACVAMHSGWAAKVGGDGFRNF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCEEEECCCCCCCCC
DGTAQHYPGFHIEATQMLLETGARSMAVDTLSLDHGISADFATHYAWLPSGRFGIENLAG
CCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHEEECCCCCCCCHHHCC
LDQVPASGATLIIGAPKHRGGTGGPARIFAMV
CCCCCCCCCEEEEECCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MCDICVMNSVKERMLSRRSLFKGGLAAAGAAAVGSTFTKATPALADGHAGVFDMTHTLSE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHH
DFPTYFGEPGFSAEQVFNFADNGFNLFNLSVNEHTGTHIDAPLHFSADGTSVDEIPVGDL
HCHHHCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCEECCCEEECCCCCCCCCCCCHHH
VAPLCVIDIAARAEDDADTTVTPDDLQAWIDANGEIPDGACVAMHSGWAAKVGGDGFRNF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCEEEECCCCCCCCC
DGTAQHYPGFHIEATQMLLETGARSMAVDTLSLDHGISADFATHYAWLPSGRFGIENLAG
CCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHEEECCCCCCCCHHHCC
LDQVPASGATLIIGAPKHRGGTGGPARIFAMV
CCCCCCCCCEEEEECCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA