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The map label for this gene is intA [H]

Identifier: 89054037

GI number: 89054037

Start: 1516603

End: 1517766

Strand: Reverse

Name: intA [H]

Synonym: Jann_1546

Alternate gene names: 89054037

Gene position: 1517766-1516603 (Counterclockwise)

Preceding gene: 89054038

Following gene: 89054034

Centisome position: 35.15

GC content: 60.91

Gene sequence:

>1164_bases
TTGGGGGATATTTTTTTGGGAAACCTAACAGCCCTTTTCATCAGATCCGCGCCGCCCGGCAAGTATGAGGACGGCCATGG
GTTGCGCCTGATCAAGCGCGTGGACGGCGGCGGGCAGTGGGTGTTTCGGTATACCTTCCTTGGTCGCCGCCGGGAAATGG
GTCTTGGCGGACTTGTCAGCCTCCCCTTGAAAGATGCGCGTGAGATGGCCAGCGACTACCGAACCATGGTGGTCAAAGGC
GTTGATCCGATCGAGCATCGGCGGCGGGAGCGCGGCGCTGCGATGAGCGGTCGCCATTTGTTGCGGGATATCGCGCTGGA
TGCGTTTGAGAGCCGCAAGGCCGACCTCAAGGGCGACGGGATCGCGGGGCGCTGGTTCAGTCCGTTGAAGCTTCACGTGC
TGCCCAAGCTCGGGCGCATGCCGGTGACCGAGATCACCCAAGTCGATGTCCGGGATGCGCTCGAGCAGATCTGGCACGCG
AAGGCCGCAACGGCCAAGAAGGCTGCAGACCGCCTAAAGATCGTCCTCGATCATGCAGCTGCTCTGGGCCTTGATGTCGA
CCTGCAAGCCGTTGCAAAGGCGAAGCAACTTTTGGGTCGGCAGCGGCATGAAACGACGTCGATCCCGAGCATGCCCTGGC
GTGATGTCCCGGCGTTCTACACGTCCCTTGAGGAACCCACGATCACACATCTGGCGCTTCGTTTGCTTATCCTAACAGGT
CTACGCTCTGCGCCTGTGCGGTTGGCGCGGATTGATGAGATCGACGGCAATGTCTGGACAATCCCGGCCGAGAACATGAA
GGCGCGGGTCGGCGTTGCAGAGGACTTCCGTGTGCCGCTCAGCGATGAGACGCAGCGTATCATCGACCTCGCCCGTCCCT
ACGAGCGCGATGGCTATCTGTTTCCGTCAGTTCGCAAGGGGGTCATCAGTGATGCAACGATGGCGCGGCTGATGGAGCGC
AGAGAGTTGGAAGCACGCCCGCATGGATTCAGAACAAGCTTGCGCACCTGGCTCGCCGAGGAGACGGACGCCCCGCATGA
GGTGGCCGAGATGGTTCTGGCGCACGTCTCCGACAGCAAGGTGGTTCGGACCTATCGCAAGACCGACTTCCTCGATCAGC
GGCGACAGCTTATGGAACGTTGGGCACAGTTGTGCATTGGATAA

Upstream 100 bases:

>100_bases
ATCGCCCTGTAGCTAGCTGACAAGATTATATAAAGTCCGTAACTGCATCTCGCTCCGTCTTGCCCCATCCCAGCAGATCC
TATACATCATAGGGGATAAA

Downstream 100 bases:

>100_bases
CGCCATGGGGACGGCGTGGGCAGCAGACATCTTAAACCTTACCGGCCCGAGGGCGGGTTTTCCTCTCGGTCCGCCTAGAT
AGAGTTTCTCCCCTTCGCCG

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MGDIFLGNLTALFIRSAPPGKYEDGHGLRLIKRVDGGGQWVFRYTFLGRRREMGLGGLVSLPLKDAREMASDYRTMVVKG
VDPIEHRRRERGAAMSGRHLLRDIALDAFESRKADLKGDGIAGRWFSPLKLHVLPKLGRMPVTEITQVDVRDALEQIWHA
KAATAKKAADRLKIVLDHAAALGLDVDLQAVAKAKQLLGRQRHETTSIPSMPWRDVPAFYTSLEEPTITHLALRLLILTG
LRSAPVRLARIDEIDGNVWTIPAENMKARVGVAEDFRVPLSDETQRIIDLARPYERDGYLFPSVRKGVISDATMARLMER
RELEARPHGFRTSLRTWLAEETDAPHEVAEMVLAHVSDSKVVRTYRKTDFLDQRRQLMERWAQLCIG

Sequences:

>Translated_387_residues
MGDIFLGNLTALFIRSAPPGKYEDGHGLRLIKRVDGGGQWVFRYTFLGRRREMGLGGLVSLPLKDAREMASDYRTMVVKG
VDPIEHRRRERGAAMSGRHLLRDIALDAFESRKADLKGDGIAGRWFSPLKLHVLPKLGRMPVTEITQVDVRDALEQIWHA
KAATAKKAADRLKIVLDHAAALGLDVDLQAVAKAKQLLGRQRHETTSIPSMPWRDVPAFYTSLEEPTITHLALRLLILTG
LRSAPVRLARIDEIDGNVWTIPAENMKARVGVAEDFRVPLSDETQRIIDLARPYERDGYLFPSVRKGVISDATMARLMER
RELEARPHGFRTSLRTWLAEETDAPHEVAEMVLAHVSDSKVVRTYRKTDFLDQRRQLMERWAQLCIG
>Mature_386_residues
GDIFLGNLTALFIRSAPPGKYEDGHGLRLIKRVDGGGQWVFRYTFLGRRREMGLGGLVSLPLKDAREMASDYRTMVVKGV
DPIEHRRRERGAAMSGRHLLRDIALDAFESRKADLKGDGIAGRWFSPLKLHVLPKLGRMPVTEITQVDVRDALEQIWHAK
AATAKKAADRLKIVLDHAAALGLDVDLQAVAKAKQLLGRQRHETTSIPSMPWRDVPAFYTSLEEPTITHLALRLLILTGL
RSAPVRLARIDEIDGNVWTIPAENMKARVGVAEDFRVPLSDETQRIIDLARPYERDGYLFPSVRKGVISDATMARLMERR
ELEARPHGFRTSLRTWLAEETDAPHEVAEMVLAHVSDSKVVRTYRKTDFLDQRRQLMERWAQLCIG

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=397, Percent_Identity=28.7153652392947, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI145693166, Length=369, Percent_Identity=30.6233062330623, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788690, Length=376, Percent_Identity=23.936170212766, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43746; Mature: 43615

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDIFLGNLTALFIRSAPPGKYEDGHGLRLIKRVDGGGQWVFRYTFLGRRREMGLGGLVS
CCCEEECCHHEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHCCCCCEEE
LPLKDAREMASDYRTMVVKGVDPIEHRRRERGAAMSGRHLLRDIALDAFESRKADLKGDG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
IAGRWFSPLKLHVLPKLGRMPVTEITQVDVRDALEQIWHAKAATAKKAADRLKIVLDHAA
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLDVDLQAVAKAKQLLGRQRHETTSIPSMPWRDVPAFYTSLEEPTITHLALRLLILTG
HHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
LRSAPVRLARIDEIDGNVWTIPAENMKARVGVAEDFRVPLSDETQRIIDLARPYERDGYL
CCCCCEEEEEEEECCCCEEEECCCCCHHHCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCC
FPSVRKGVISDATMARLMERRELEARPHGFRTSLRTWLAEETDAPHEVAEMVLAHVSDSK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
VVRTYRKTDFLDQRRQLMERWAQLCIG
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDIFLGNLTALFIRSAPPGKYEDGHGLRLIKRVDGGGQWVFRYTFLGRRREMGLGGLVS
CCEEECCHHEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHCCCCCEEE
LPLKDAREMASDYRTMVVKGVDPIEHRRRERGAAMSGRHLLRDIALDAFESRKADLKGDG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
IAGRWFSPLKLHVLPKLGRMPVTEITQVDVRDALEQIWHAKAATAKKAADRLKIVLDHAA
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLDVDLQAVAKAKQLLGRQRHETTSIPSMPWRDVPAFYTSLEEPTITHLALRLLILTG
HHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
LRSAPVRLARIDEIDGNVWTIPAENMKARVGVAEDFRVPLSDETQRIIDLARPYERDGYL
CCCCCEEEEEEEECCCCEEEECCCCCHHHCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCC
FPSVRKGVISDATMARLMERRELEARPHGFRTSLRTWLAEETDAPHEVAEMVLAHVSDSK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
VVRTYRKTDFLDQRRQLMERWAQLCIG
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]