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The map label for this gene is betC [H]

Identifier: 89053985

GI number: 89053985

Start: 1465402

End: 1466910

Strand: Reverse

Name: betC [H]

Synonym: Jann_1494

Alternate gene names: 89053985

Gene position: 1466910-1465402 (Counterclockwise)

Preceding gene: 89053986

Following gene: 89053984

Centisome position: 33.97

GC content: 60.9

Gene sequence:

>1509_bases
ATGACCCAACCTAACATCCTGATAGTAATGGTGGATCAGTTGAACGGCACGTTGTTCCCGGACGGCCCGGCGGACTGGCT
GCACACGCCCAATCTGGACCGCTTGGCAGCCCGCTCCACACGATTTGCCAACACGTATACCGCCTCTCCACTCTGCGCGC
CGGCCCGCGCGTCGTTCATGTCGGGCCAATTACCGTCGCGCACCGGCGTCTATGACAACGCCGCGGAATTCACGTCGTCA
ATCCCGACCTACGCCCATCACCTGCGCCGTGCGGGCTACTATACTGCGTTGTCGGGCAAGATGCATTTTGTGGGGCCGGA
CCAGCTGCACGGGTTTGAACAGCGGCTGACCACGGATATCTACCCGGCTGATTTCGGTTGGACGCCGGACTACCGCAAGC
CCGGTGAGCGGATCGATTGGTGGTATCACAACATGGGCTCCGTCACCGGATCCGGCGTTGCTGAGATCACCAACCAGATG
GAATATGACGACGCCGTGGCGTTTGAGGCGGAGCAAAAACTCTACGACCTGTCGCGTGGGGCCGATCGGCGCCCGTGGTG
TCTGACGGTCAGTTTCACCCACCCCCATGACCCCTATGTCGCGCGCCGCGAGTTCTGGGATTTGTATAACGATTGCAATC
GCTTGATACCTGAGATCGGGGCGATCCCCTATGCAGAGCAGGACAACCATTCCAAGCGCATTCTGGACGCGAATGATCTG
GGTAATTTCGATATTACGGATCAGGACATCGCCCGGTCGCGCCAGGCCTATTTCGCCAACATCTCCTACCTCGATCAGAA
GATCGGCGGCGTGCTGGACGTGCTGGAGCGCACGCGGCAGGAGGCGATCGTGATCTTCATCTCGGACCACGGTGACATGT
TAGGCGAACGTGGCTTGTGGTTCAAAATGTCCTTCTATGAGGGCTCGGCTCGCGTGCCGCTGATGATCTCCGCGCCGGGG
ATGGAGCCTGGGATGGTCTCGGACCCGGTCTCCACCATCGACCTCTGCCCCACCCTTTGCGACCTCGCGGGCGTGTCGAT
GGACGAGGTGATGCCGTGGACCGATGGCGAAACGTTAACGCCGTTAGGAAAGGGCGCCAAACGGGTCAATCCGGTGGCGA
TGGAATACGCGGCGGAAGGGTCGTACTCTCCCGTCGTGGGCCTGCGCCAAGGCCAATGGAAATACACCAATTGCGCGATT
GATCCGGAGCAATTGTTCGATCTGGCCGCCGATCCCCATGAGCTGAACGACCTGTCCGAAAACCCCGCCCATGCGGCGAC
CTTGGAGGCGTTTCGGGTCAAGGCAGCCGCCCGCTGGGATCTGGAGGCGTTCGACGCAAACGTTCGGCAATCCCAGGCCC
GCCGCTGGGTCGTCTACGAGGCGCTGCGCAACGGCGCCTACTACCCGTGGGATTTTCAACCCCTGCGCGACGCGTCCGAG
CGCTACATGCGCAACCACATGGACCTCAACGTTCTTGAGGAAAATCAACGCTTTCCCCGGGGCGAATGA

Upstream 100 bases:

>100_bases
TCTGCCCTCACTGCGGCATCGACAGCGTGATCGGCGATGCGTCCGGCCACCCCGTCACACCCGACTTCCTTGGCAAGATG
AACGCGCATTGGTTCCGGAC

Downstream 100 bases:

>100_bases
CCCCCAGACGATCAGGTGACCGATGCAACCGACTGCTTCCCATTTCGTGAACGGCGCGTATCTGGAAGATACCGCTGGCA
CGCCGATGCCCGTCATTTTC

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTQPNILIVMVDQLNGTLFPDGPADWLHTPNLDRLAARSTRFANTYTASPLCAPARASFMSGQLPSRTGVYDNAAEFTSS
IPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEQRLTTDIYPADFGWTPDYRKPGERIDWWYHNMGSVTGSGVAEITNQM
EYDDAVAFEAEQKLYDLSRGADRRPWCLTVSFTHPHDPYVARREFWDLYNDCNRLIPEIGAIPYAEQDNHSKRILDANDL
GNFDITDQDIARSRQAYFANISYLDQKIGGVLDVLERTRQEAIVIFISDHGDMLGERGLWFKMSFYEGSARVPLMISAPG
MEPGMVSDPVSTIDLCPTLCDLAGVSMDEVMPWTDGETLTPLGKGAKRVNPVAMEYAAEGSYSPVVGLRQGQWKYTNCAI
DPEQLFDLAADPHELNDLSENPAHAATLEAFRVKAAARWDLEAFDANVRQSQARRWVVYEALRNGAYYPWDFQPLRDASE
RYMRNHMDLNVLEENQRFPRGE

Sequences:

>Translated_502_residues
MTQPNILIVMVDQLNGTLFPDGPADWLHTPNLDRLAARSTRFANTYTASPLCAPARASFMSGQLPSRTGVYDNAAEFTSS
IPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEQRLTTDIYPADFGWTPDYRKPGERIDWWYHNMGSVTGSGVAEITNQM
EYDDAVAFEAEQKLYDLSRGADRRPWCLTVSFTHPHDPYVARREFWDLYNDCNRLIPEIGAIPYAEQDNHSKRILDANDL
GNFDITDQDIARSRQAYFANISYLDQKIGGVLDVLERTRQEAIVIFISDHGDMLGERGLWFKMSFYEGSARVPLMISAPG
MEPGMVSDPVSTIDLCPTLCDLAGVSMDEVMPWTDGETLTPLGKGAKRVNPVAMEYAAEGSYSPVVGLRQGQWKYTNCAI
DPEQLFDLAADPHELNDLSENPAHAATLEAFRVKAAARWDLEAFDANVRQSQARRWVVYEALRNGAYYPWDFQPLRDASE
RYMRNHMDLNVLEENQRFPRGE
>Mature_501_residues
TQPNILIVMVDQLNGTLFPDGPADWLHTPNLDRLAARSTRFANTYTASPLCAPARASFMSGQLPSRTGVYDNAAEFTSSI
PTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEQRLTTDIYPADFGWTPDYRKPGERIDWWYHNMGSVTGSGVAEITNQME
YDDAVAFEAEQKLYDLSRGADRRPWCLTVSFTHPHDPYVARREFWDLYNDCNRLIPEIGAIPYAEQDNHSKRILDANDLG
NFDITDQDIARSRQAYFANISYLDQKIGGVLDVLERTRQEAIVIFISDHGDMLGERGLWFKMSFYEGSARVPLMISAPGM
EPGMVSDPVSTIDLCPTLCDLAGVSMDEVMPWTDGETLTPLGKGAKRVNPVAMEYAAEGSYSPVVGLRQGQWKYTNCAID
PEQLFDLAADPHELNDLSENPAHAATLEAFRVKAAARWDLEAFDANVRQSQARRWVVYEALRNGAYYPWDFQPLRDASER
YMRNHMDLNVLEENQRFPRGE

Specific function: Converts choline-O-sulfate into choline [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4557659, Length=408, Percent_Identity=29.9019607843137, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI39930577, Length=198, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI5360208, Length=324, Percent_Identity=29.320987654321, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504061, Length=468, Percent_Identity=23.2905982905983, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4503899, Length=435, Percent_Identity=25.7471264367816, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI262118210, Length=348, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI53831991, Length=115, Percent_Identity=40, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790112, Length=437, Percent_Identity=27.9176201372998, Blast_Score=149, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17559078, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR017785
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.6 [H]

Molecular weight: Translated: 56767; Mature: 56636

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPNILIVMVDQLNGTLFPDGPADWLHTPNLDRLAARSTRFANTYTASPLCAPARASFM
CCCCCEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGQLPSRTGVYDNAAEFTSSIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEQRLTTDI
CCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHCCC
YPADFGWTPDYRKPGERIDWWYHNMGSVTGSGVAEITNQMEYDDAVAFEAEQKLYDLSRG
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
ADRRPWCLTVSFTHPHDPYVARREFWDLYNDCNRLIPEIGAIPYAEQDNHSKRILDANDL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
GNFDITDQDIARSRQAYFANISYLDQKIGGVLDVLERTRQEAIVIFISDHGDMLGERGLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCE
FKMSFYEGSARVPLMISAPGMEPGMVSDPVSTIDLCPTLCDLAGVSMDEVMPWTDGETLT
EEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEC
PLGKGAKRVNPVAMEYAAEGSYSPVVGLRQGQWKYTNCAIDPEQLFDLAADPHELNDLSE
CCCCCCHHCCHHHHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCHHHHCCCC
NPAHAATLEAFRVKAAARWDLEAFDANVRQSQARRWVVYEALRNGAYYPWDFQPLRDASE
CCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RYMRNHMDLNVLEENQRFPRGE
HHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
TQPNILIVMVDQLNGTLFPDGPADWLHTPNLDRLAARSTRFANTYTASPLCAPARASFM
CCCCEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGQLPSRTGVYDNAAEFTSSIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEQRLTTDI
CCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHCCC
YPADFGWTPDYRKPGERIDWWYHNMGSVTGSGVAEITNQMEYDDAVAFEAEQKLYDLSRG
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
ADRRPWCLTVSFTHPHDPYVARREFWDLYNDCNRLIPEIGAIPYAEQDNHSKRILDANDL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
GNFDITDQDIARSRQAYFANISYLDQKIGGVLDVLERTRQEAIVIFISDHGDMLGERGLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCE
FKMSFYEGSARVPLMISAPGMEPGMVSDPVSTIDLCPTLCDLAGVSMDEVMPWTDGETLT
EEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEC
PLGKGAKRVNPVAMEYAAEGSYSPVVGLRQGQWKYTNCAIDPEQLFDLAADPHELNDLSE
CCCCCCHHCCHHHHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCHHHHCCCC
NPAHAATLEAFRVKAAARWDLEAFDANVRQSQARRWVVYEALRNGAYYPWDFQPLRDASE
CCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RYMRNHMDLNVLEENQRFPRGE
HHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141699; 11481430; 9736747 [H]