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The map label for this gene is glnA [H]

Identifier: 89053937

GI number: 89053937

Start: 1415478

End: 1416848

Strand: Direct

Name: glnA [H]

Synonym: Jann_1446

Alternate gene names: 89053937

Gene position: 1415478-1416848 (Clockwise)

Preceding gene: 89053936

Following gene: 89053938

Centisome position: 32.78

GC content: 65.21

Gene sequence:

>1371_bases
TTGACGTCAAACGATATTCTCGAACAGGTTTGCGCGAAAGGGATCGAGACCATCCGCGTGGTGTTCGCCGATCCCCACGG
CATTCTGCGCGGCAAGACGATCACCGCGTCGGCCCTGCCTGGCGCGCTGGAAAACGGCATCCGCGTGCCGTCGACGCTGT
TGCTCAAGGACCTGTCCCACCGCACCGTCTTTCCGGTCTGGCATGCAAATGGCGCACCGATGCGGGGGGCCTCCGACGTC
CTCCTGCGTCCCGATCCGGCCAGTTTCAGACAATTGCCCCACGCGCCCCATTCAGCGCTGATCCATTGTGATATAACGGC
TTTGGATGGCGCGCCGATCCCCGTGGCGCCCCGTGACATTCTGCGCCGCTGCGAGGAGGCCTTGGCCGAGGAGGGGCTGG
CGGCCGTGTTCGGGCTGGAGGTGGAGTTCCAGATCTACCGCGTCACCGACCCGCATCTTGCGCCGGAGCACGCCACCATG
CCGGGCCGTCCGCCGCTGGTCGAAAACACGACGCAAGGCTACCAATACCTGACCGAAACGCGCTACGCGGAGGCCGAAGA
CATGCTCGACCGTCTTCGCCGCGCCGCGGAGGAGATGGGGATCGACGTCCGCTCTGTCGAGATCGAAATGGGCCCCTCGC
AATTCGAATTTACCTTCGCGCCCGGCCCCCCCAGCGCGGTCGCGGAGGCCATCATCACCTTCCGCATGCTGGCGAGGGAT
CTCTGCGCGCGACACGGGCTTTTGGCGAGTTTCATGCCCAAGCCTGCCCTGCCCAATGCGGCCGCCAATGGCTGGCATAT
CCACCAGAGCCTGACTGACGCGACCGGAGCTAACCTTTTCACGCCAAACGACAATACTCTCACCGATACCGCCGCCCATT
GGATCGCGGGGCTGCTGGATCACGGCCCCGCCTGCTGCCTGCTGACCAACCCCACCGTCAACAGCTACAAGCGGTTCGTC
CCCCATCAACTGGCCCCCAACCGCGTCGGGTGGGCCTATGACAATCGTGGCGCCATGGTCCGCGCATTGACCGCGCCGGG
CGACCCTGCCAGCCGGGTTGAAAACCGCCTGCCGGACAGCGCCATCAATCCGTATCTCGCCTTCGCCGCGCAGATTATCT
CGGGCCTCGACGGGCTGCGAAGCGCCACGCAGCCACCGCCGCCGATGGCTGATCCCTATGGCGCTGACGCCCCCGATTTG
CCGTCCAACCTGGGGGCCGCAATCGATGCTTTCGCGGCCTCGGACACCCTGCGCGCGGCCCTGACGCCGGAGGTCGCGGA
CTGGCTGATCACCCTCAAACGGGCGGAATGGGACCGCTATCTTGGCCATATCTCGGATTGGGAACAGGCGGAGTATTTTG
CCACCTTCTAG

Upstream 100 bases:

>100_bases
CGCTCAGCAACGACGCCATCGCACCCGACGACGATTGGGTGGCGGCCAGCGAGGCGGCAGACCAGGCACGGCGCGGCACC
TGCCAGTGGGATGCAAGCGT

Downstream 100 bases:

>100_bases
GGTGCGTGCATCGGTAACTTTCCTGTAGGTTTTCCGTAACTACAGCCTTGATCTGCCGCGCGATCCGTCCAAACCTAGGG
CGACAGCAACAGGAGCACCG

Product: L-glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTSNDILEQVCAKGIETIRVVFADPHGILRGKTITASALPGALENGIRVPSTLLLKDLSHRTVFPVWHANGAPMRGASDV
LLRPDPASFRQLPHAPHSALIHCDITALDGAPIPVAPRDILRRCEEALAEEGLAAVFGLEVEFQIYRVTDPHLAPEHATM
PGRPPLVENTTQGYQYLTETRYAEAEDMLDRLRRAAEEMGIDVRSVEIEMGPSQFEFTFAPGPPSAVAEAIITFRMLARD
LCARHGLLASFMPKPALPNAAANGWHIHQSLTDATGANLFTPNDNTLTDTAAHWIAGLLDHGPACCLLTNPTVNSYKRFV
PHQLAPNRVGWAYDNRGAMVRALTAPGDPASRVENRLPDSAINPYLAFAAQIISGLDGLRSATQPPPPMADPYGADAPDL
PSNLGAAIDAFAASDTLRAALTPEVADWLITLKRAEWDRYLGHISDWEQAEYFATF

Sequences:

>Translated_456_residues
MTSNDILEQVCAKGIETIRVVFADPHGILRGKTITASALPGALENGIRVPSTLLLKDLSHRTVFPVWHANGAPMRGASDV
LLRPDPASFRQLPHAPHSALIHCDITALDGAPIPVAPRDILRRCEEALAEEGLAAVFGLEVEFQIYRVTDPHLAPEHATM
PGRPPLVENTTQGYQYLTETRYAEAEDMLDRLRRAAEEMGIDVRSVEIEMGPSQFEFTFAPGPPSAVAEAIITFRMLARD
LCARHGLLASFMPKPALPNAAANGWHIHQSLTDATGANLFTPNDNTLTDTAAHWIAGLLDHGPACCLLTNPTVNSYKRFV
PHQLAPNRVGWAYDNRGAMVRALTAPGDPASRVENRLPDSAINPYLAFAAQIISGLDGLRSATQPPPPMADPYGADAPDL
PSNLGAAIDAFAASDTLRAALTPEVADWLITLKRAEWDRYLGHISDWEQAEYFATF
>Mature_455_residues
TSNDILEQVCAKGIETIRVVFADPHGILRGKTITASALPGALENGIRVPSTLLLKDLSHRTVFPVWHANGAPMRGASDVL
LRPDPASFRQLPHAPHSALIHCDITALDGAPIPVAPRDILRRCEEALAEEGLAAVFGLEVEFQIYRVTDPHLAPEHATMP
GRPPLVENTTQGYQYLTETRYAEAEDMLDRLRRAAEEMGIDVRSVEIEMGPSQFEFTFAPGPPSAVAEAIITFRMLARDL
CARHGLLASFMPKPALPNAAANGWHIHQSLTDATGANLFTPNDNTLTDTAAHWIAGLLDHGPACCLLTNPTVNSYKRFVP
HQLAPNRVGWAYDNRGAMVRALTAPGDPASRVENRLPDSAINPYLAFAAQIISGLDGLRSATQPPPPMADPYGADAPDLP
SNLGAAIDAFAASDTLRAALTPEVADWLITLKRAEWDRYLGHISDWEQAEYFATF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=448, Percent_Identity=26.1160714285714, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI1790301, Length=394, Percent_Identity=30.4568527918782, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI87081870, Length=419, Percent_Identity=28.8782816229117, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 49499; Mature: 49367

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNDILEQVCAKGIETIRVVFADPHGILRGKTITASALPGALENGIRVPSTLLLKDLSH
CCCHHHHHHHHHCCHHEEEEEEECCCCCCCCCEEEHHHCCHHHHCCCCCCHHHHHHHCCC
RTVFPVWHANGAPMRGASDVLLRPDPASFRQLPHAPHSALIHCDITALDGAPIPVAPRDI
CEEEEEEECCCCCCCCCCCEEECCCCHHHHHCCCCCCCEEEEEEEEEECCCCCCCCHHHH
LRRCEEALAEEGLAAVFGLEVEFQIYRVTDPHLAPEHATMPGRPPLVENTTQGYQYLTET
HHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RYAEAEDMLDRLRRAAEEMGIDVRSVEIEMGPSQFEFTFAPGPPSAVAEAIITFRMLARD
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LCARHGLLASFMPKPALPNAAANGWHIHQSLTDATGANLFTPNDNTLTDTAAHWIAGLLD
HHHHCCHHHHHCCCCCCCCCCCCCEEEHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHC
HGPACCLLTNPTVNSYKRFVPHQLAPNRVGWAYDNRGAMVRALTAPGDPASRVENRLPDS
CCCEEEEEECCCHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHCCCCH
AINPYLAFAAQIISGLDGLRSATQPPPPMADPYGADAPDLPSNLGAAIDAFAASDTLRAA
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTPEVADWLITLKRAEWDRYLGHISDWEQAEYFATF
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECC
>Mature Secondary Structure 
TSNDILEQVCAKGIETIRVVFADPHGILRGKTITASALPGALENGIRVPSTLLLKDLSH
CCHHHHHHHHHCCHHEEEEEEECCCCCCCCCEEEHHHCCHHHHCCCCCCHHHHHHHCCC
RTVFPVWHANGAPMRGASDVLLRPDPASFRQLPHAPHSALIHCDITALDGAPIPVAPRDI
CEEEEEEECCCCCCCCCCCEEECCCCHHHHHCCCCCCCEEEEEEEEEECCCCCCCCHHHH
LRRCEEALAEEGLAAVFGLEVEFQIYRVTDPHLAPEHATMPGRPPLVENTTQGYQYLTET
HHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RYAEAEDMLDRLRRAAEEMGIDVRSVEIEMGPSQFEFTFAPGPPSAVAEAIITFRMLARD
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LCARHGLLASFMPKPALPNAAANGWHIHQSLTDATGANLFTPNDNTLTDTAAHWIAGLLD
HHHHCCHHHHHCCCCCCCCCCCCCEEEHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHC
HGPACCLLTNPTVNSYKRFVPHQLAPNRVGWAYDNRGAMVRALTAPGDPASRVENRLPDS
CCCEEEEEECCCHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHCCCCH
AINPYLAFAAQIISGLDGLRSATQPPPPMADPYGADAPDLPSNLGAAIDAFAASDTLRAA
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTPEVADWLITLKRAEWDRYLGHISDWEQAEYFATF
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7916055 [H]