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The map label for this gene is pcaR [H]

Identifier: 89053935

GI number: 89053935

Start: 1413406

End: 1414071

Strand: Reverse

Name: pcaR [H]

Synonym: Jann_1444

Alternate gene names: 89053935

Gene position: 1414071-1413406 (Counterclockwise)

Preceding gene: 89053942

Following gene: 89053934

Centisome position: 32.75

GC content: 68.02

Gene sequence:

>666_bases
ATGTCTAAAACGCTGTCCACCACCTTGCTGAAAGGCTTGGACGTCCTGTCGGCGTTTGAGGGCGCGTCGTCCCTGACCCT
CAGCCAGATCGCAGAGCGCACGGGGCTGGACCGATCTACCGCCCGCCGCATGGCGCTGACGCTGGTCGAGGCGCGGTGGA
TCACCCAAACCGGCCGCGCCTTCGCCCTCGCGCCCCACGTCCTGCGGCCAGCAGGCGCCTATCTGCAAGCGGGCGCGTTC
GGGCGGGTGGTGCAACCGATCCTGAACGCCCACGCCGAAACCCTTGGCGGCGAAATCAGCCTCGCCCTGCGCGATGGCGA
TCACGCCGTCTATGTGGCCCACTCTGCCCGCCCGGGTGCGCGGGTGTCTCTTGGCTTGACGGTCGGCTCCACCCTGCCGC
TGGACACCACCGCCATTGGGCGCGTGCTGCTGGGTGGTGATCAACCCTCACAAGTGATGCGCGGCGCGTATGAGCCCGGC
ATCTGCGGCCTCGCCGTGCCAGTCGGCCCAACCCATGCGCCGCAAGCGGCCCTCGGCACGACCCTTCCCCTCGCCTTGCC
ACAGCTGGAGGATCGGCTAGACACGACGTTGGCCACCTTACATATGGCAGCTGCCGACTTGCACGACATGCCGGGGCTGA
CCCAACCCGCGTCGCTGCGTCAATGA

Upstream 100 bases:

>100_bases
TCATCGGCTCGGGCTCCTTCGCGAAATGTGCGATATACGCACAATTGTTGACATTCTGAGTGTGGCGTGGCTGTCTGTTT
CTGTCAACGAAAGTCGCGCC

Downstream 100 bases:

>100_bases
CGCCCCGACCAACCCTTGCGCTTTGAGACTTTTGGTCTCAAAATTACACAAATTCTGGCCCTATGGTCGGAGAAAATTGG
CCATAGGGCCGACGCAGCAG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSKTLSTTLLKGLDVLSAFEGASSLTLSQIAERTGLDRSTARRMALTLVEARWITQTGRAFALAPHVLRPAGAYLQAGAF
GRVVQPILNAHAETLGGEISLALRDGDHAVYVAHSARPGARVSLGLTVGSTLPLDTTAIGRVLLGGDQPSQVMRGAYEPG
ICGLAVPVGPTHAPQAALGTTLPLALPQLEDRLDTTLATLHMAAADLHDMPGLTQPASLRQ

Sequences:

>Translated_221_residues
MSKTLSTTLLKGLDVLSAFEGASSLTLSQIAERTGLDRSTARRMALTLVEARWITQTGRAFALAPHVLRPAGAYLQAGAF
GRVVQPILNAHAETLGGEISLALRDGDHAVYVAHSARPGARVSLGLTVGSTLPLDTTAIGRVLLGGDQPSQVMRGAYEPG
ICGLAVPVGPTHAPQAALGTTLPLALPQLEDRLDTTLATLHMAAADLHDMPGLTQPASLRQ
>Mature_220_residues
SKTLSTTLLKGLDVLSAFEGASSLTLSQIAERTGLDRSTARRMALTLVEARWITQTGRAFALAPHVLRPAGAYLQAGAFG
RVVQPILNAHAETLGGEISLALRDGDHAVYVAHSARPGARVSLGLTVGSTLPLDTTAIGRVLLGGDQPSQVMRGAYEPGI
CGLAVPVGPTHAPQAALGTTLPLALPQLEDRLDTTLATLHMAAADLHDMPGLTQPASLRQ

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 22977; Mature: 22846

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTLSTTLLKGLDVLSAFEGASSLTLSQIAERTGLDRSTARRMALTLVEARWITQTGRA
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
FALAPHVLRPAGAYLQAGAFGRVVQPILNAHAETLGGEISLALRDGDHAVYVAHSARPGA
EEECCHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCC
RVSLGLTVGSTLPLDTTAIGRVLLGGDQPSQVMRGAYEPGICGLAVPVGPTHAPQAALGT
EEEEEEEECCCCCCCHHHHHHEEECCCCHHHHHHCCCCCCCCEEEECCCCCCCCHHHHCC
TLPLALPQLEDRLDTTLATLHMAAADLHDMPGLTQPASLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTLSTTLLKGLDVLSAFEGASSLTLSQIAERTGLDRSTARRMALTLVEARWITQTGRA
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
FALAPHVLRPAGAYLQAGAFGRVVQPILNAHAETLGGEISLALRDGDHAVYVAHSARPGA
EEECCHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCC
RVSLGLTVGSTLPLDTTAIGRVLLGGDQPSQVMRGAYEPGICGLAVPVGPTHAPQAALGT
EEEEEEEECCCCCCCHHHHHHEEECCCCHHHHHHCCCCCCCCEEEECCCCCCCCHHHHCC
TLPLALPQLEDRLDTTLATLHMAAADLHDMPGLTQPASLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]