Click here to switch to the map view.

The map label for this gene is iolE [H]

Identifier: 89053913

GI number: 89053913

Start: 1391507

End: 1392400

Strand: Direct

Name: iolE [H]

Synonym: Jann_1422

Alternate gene names: 89053913

Gene position: 1391507-1392400 (Clockwise)

Preceding gene: 89053912

Following gene: 89053914

Centisome position: 32.23

GC content: 56.15

Gene sequence:

>894_bases
ATGACAATTCGTATCGGTAACGCACCTTGTTCGTGGGGTGTGGAATTCGCGGACGATCCACGAAATCCAACTTGGCAGTC
GGTCCTGGAGGACTGTGCGGCGGCAGGCTACAAGGGGATCGAGCTGGGGCCGGTGGGCTTCATGCCGGAGGATCCGAACA
TCCTTGGCGATGCGTTAGCCCAGAATGATCTGGAGTTGATTGGGGGCGTTGTGTTCCGGCCCTTTCACGACCCTGACGCT
TGGGACGACGTATTGGACGGTTCGGTACGAACCTGCAAAGCGCTCTCTGCCCATGGCGCGCAACACCTTGTTCTGATTGA
CTCTATCTCACCTCGCCGTGCGCCAACTGCGGGCCGGGCTGAGACGGCAGAACAGATGGGTAAGGCCGAGTGGATCGCCT
ATCGGGACAGGATCGCCCAGATCGCGCGCATGGGGACGGAGGAGTATGGATTAACTGTTGGCATCCATGCCCACGCGGCG
GGGTTCATGGACTTCGAGCCAGAGCTGGACCGGCTGCTGGACGAGGTGCCTGAAGACATCCTGAAGATATGCTTTGACAC
AGGCCACCACTCCTACGCCGGCTATGATCCCGTGGCATTCATGGCCCGTTCGATTGATCGAATTTCCTACATGCATTTCA
AAGATATAGATCCGATTGTTAAAGCTGACGTCATCACGAACGGCACGGACTTCTACACAGCCTGTGGACAAAAAATCTTC
TGCAATCTGGGACAGGGCGATGTGCAGTTTGAAGCTGTGCGTAAGATTTTGATCGATGCGGGATTTGAGGGCTGGTGCAC
CGTGGAACAGGATTGCGATCCCCTGTTGGACGTGCGGCCGCTGGATGATGCGCGAGCCAACCGGAAATACCTTGAATCTA
TTGGCTTTAATTGA

Upstream 100 bases:

>100_bases
TTCCGCGACGGGTTGGCTGTGAGCCGCGTTATCGACACTGCATTTAAGGCTGCCGAAACAGGCGGTTGGGCTTCTATCCC
TCAGGATTGAAAGGGAAATC

Downstream 100 bases:

>100_bases
AGGCGTGATGAGATGAGCAAGCTGAAATGGGGTATGATCGGGGGCGGTGAGGGCTCTCAAATCGGGCCGGCGCATCGTTT
GGGCGCGCAGGCCGATGGGA

Product: xylose isomerase-like protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTIRIGNAPCSWGVEFADDPRNPTWQSVLEDCAAAGYKGIELGPVGFMPEDPNILGDALAQNDLELIGGVVFRPFHDPDA
WDDVLDGSVRTCKALSAHGAQHLVLIDSISPRRAPTAGRAETAEQMGKAEWIAYRDRIAQIARMGTEEYGLTVGIHAHAA
GFMDFEPELDRLLDEVPEDILKICFDTGHHSYAGYDPVAFMARSIDRISYMHFKDIDPIVKADVITNGTDFYTACGQKIF
CNLGQGDVQFEAVRKILIDAGFEGWCTVEQDCDPLLDVRPLDDARANRKYLESIGFN

Sequences:

>Translated_297_residues
MTIRIGNAPCSWGVEFADDPRNPTWQSVLEDCAAAGYKGIELGPVGFMPEDPNILGDALAQNDLELIGGVVFRPFHDPDA
WDDVLDGSVRTCKALSAHGAQHLVLIDSISPRRAPTAGRAETAEQMGKAEWIAYRDRIAQIARMGTEEYGLTVGIHAHAA
GFMDFEPELDRLLDEVPEDILKICFDTGHHSYAGYDPVAFMARSIDRISYMHFKDIDPIVKADVITNGTDFYTACGQKIF
CNLGQGDVQFEAVRKILIDAGFEGWCTVEQDCDPLLDVRPLDDARANRKYLESIGFN
>Mature_296_residues
TIRIGNAPCSWGVEFADDPRNPTWQSVLEDCAAAGYKGIELGPVGFMPEDPNILGDALAQNDLELIGGVVFRPFHDPDAW
DDVLDGSVRTCKALSAHGAQHLVLIDSISPRRAPTAGRAETAEQMGKAEWIAYRDRIAQIARMGTEEYGLTVGIHAHAAG
FMDFEPELDRLLDEVPEDILKICFDTGHHSYAGYDPVAFMARSIDRISYMHFKDIDPIVKADVITNGTDFYTACGQKIFC
NLGQGDVQFEAVRKILIDAGFEGWCTVEQDCDPLLDVRPLDDARANRKYLESIGFN

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 32798; Mature: 32667

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRIGNAPCSWGVEFADDPRNPTWQSVLEDCAAAGYKGIELGPVGFMPEDPNILGDALA
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHH
QNDLELIGGVVFRPFHDPDAWDDVLDGSVRTCKALSAHGAQHLVLIDSISPRRAPTAGRA
HCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
ETAEQMGKAEWIAYRDRIAQIARMGTEEYGLTVGIHAHAAGFMDFEPELDRLLDEVPEDI
HHHHHHCHHHHHHHHHHHHHHHHCCCHHHCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHH
LKICFDTGHHSYAGYDPVAFMARSIDRISYMHFKDIDPIVKADVITNGTDFYTACGQKIF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCHHHHHCCCCEE
CNLGQGDVQFEAVRKILIDAGFEGWCTVEQDCDPLLDVRPLDDARANRKYLESIGFN
EECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIRIGNAPCSWGVEFADDPRNPTWQSVLEDCAAAGYKGIELGPVGFMPEDPNILGDALA
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHH
QNDLELIGGVVFRPFHDPDAWDDVLDGSVRTCKALSAHGAQHLVLIDSISPRRAPTAGRA
HCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
ETAEQMGKAEWIAYRDRIAQIARMGTEEYGLTVGIHAHAAGFMDFEPELDRLLDEVPEDI
HHHHHHCHHHHHHHHHHHHHHHHCCCHHHCEEEEEEHHHCCCCCCCHHHHHHHHHHHHHH
LKICFDTGHHSYAGYDPVAFMARSIDRISYMHFKDIDPIVKADVITNGTDFYTACGQKIF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCHHHHHCCCCEE
CNLGQGDVQFEAVRKILIDAGFEGWCTVEQDCDPLLDVRPLDDARANRKYLESIGFN
EECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA