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The map label for this gene is murQ

Identifier: 89053848

GI number: 89053848

Start: 1321384

End: 1322280

Strand: Reverse

Name: murQ

Synonym: Jann_1357

Alternate gene names: 89053848

Gene position: 1322280-1321384 (Counterclockwise)

Preceding gene: 89053853

Following gene: 89053847

Centisome position: 30.62

GC content: 62.65

Gene sequence:

>897_bases
ATGTTACAGCGTCAAACAGAGCAATTGCATATGGCCGCGAAGGGCCTTGATGCCTTGCCGATGACTGACGCAGCCCTCAT
CCTTGCACGGGCGCATCGCGATGCTTTGGATGCTGTCACCTCCTGCGCAACTGAACTGGCGTGCGCCGGTGAACGTATGG
CCGACGTGATCAAGAGCGGGGGAACGCTTCATTATGTTGCGGCGGGCTCGTCCGGCTTGATGGCGATGGCGGACGCCTGT
GAGCTGGCAGGCACTTTCGGCATCGACCTCGCCCAGATCACCATTCATATGGCTGGCGGCATTCCGACGGATGCAGTCAT
GCCCGGTGAGACAGAGGACGACGCTGAAGCCGCGCAACGGATTGCAGACGCCATAAACCCGCGCGATGCCGTTATCCTGG
TGAGCGCGTCCGGATCGACGCCCTACGCGGTCGAAGCTGCACAGCGGGCCCGCGCAATAGGCGCTACAACGATTTGCATC
GCCAACAACGCGGGCACGCCGCTTCTGGGCCTCGCGAACATTGCCATCTGCTTGGCAACGCCCGCAGAGGTTCTCGCCGG
ATCAACACGGATGGGGGCGGGCACGGCCCAGAAGGCGGCGCTCAACACCATGTCAACCGTCATGGGCCTGGCGCTTGGCC
ATGTGCATGACGGGATGATGGTCAATGTGCGCGCCGACAATGCGAAGTTGCGGGCGCGGGCGGTTGGGATGATCGCGATC
ATTGCCAATGTGTCCGAGACCCGCGCGGAACACTGTCTTGCCACAGCCGAGAACGAGGTGAAGCCTGCGGTCCTGCTCGC
CGCGGGCGCATCGGATTTGAACGACGCCATGGCCCGCCTTTCGCGGACCGATGGTATTCTCCGCCCTGCTTTGGCGGAAC
TTATGGGTCGTCGCTGA

Upstream 100 bases:

>100_bases
AATAAGCTACCAAAAACAGTCCTTTTTTGCCCGCAAAAGAAACTTCTTGGCACAAAGGTATTAAAAAGGTATCAAATAAC
GAATCCTTGGGGGAGAGATC

Downstream 100 bases:

>100_bases
TGAACGACCGGGATCAAAGGACTTAAGGGAGGAAACCAAATGTCCATGAAGAAACTTACCGCCAGCCTGCTGGCCACAAC
CATGCTGGTCGGCACCGCCG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLQRQTEQLHMAAKGLDALPMTDAALILARAHRDALDAVTSCATELACAGERMADVIKSGGTLHYVAAGSSGLMAMADAC
ELAGTFGIDLAQITIHMAGGIPTDAVMPGETEDDAEAAQRIADAINPRDAVILVSASGSTPYAVEAAQRARAIGATTICI
ANNAGTPLLGLANIAICLATPAEVLAGSTRMGAGTAQKAALNTMSTVMGLALGHVHDGMMVNVRADNAKLRARAVGMIAI
IANVSETRAEHCLATAENEVKPAVLLAAGASDLNDAMARLSRTDGILRPALAELMGRR

Sequences:

>Translated_298_residues
MLQRQTEQLHMAAKGLDALPMTDAALILARAHRDALDAVTSCATELACAGERMADVIKSGGTLHYVAAGSSGLMAMADAC
ELAGTFGIDLAQITIHMAGGIPTDAVMPGETEDDAEAAQRIADAINPRDAVILVSASGSTPYAVEAAQRARAIGATTICI
ANNAGTPLLGLANIAICLATPAEVLAGSTRMGAGTAQKAALNTMSTVMGLALGHVHDGMMVNVRADNAKLRARAVGMIAI
IANVSETRAEHCLATAENEVKPAVLLAAGASDLNDAMARLSRTDGILRPALAELMGRR
>Mature_298_residues
MLQRQTEQLHMAAKGLDALPMTDAALILARAHRDALDAVTSCATELACAGERMADVIKSGGTLHYVAAGSSGLMAMADAC
ELAGTFGIDLAQITIHMAGGIPTDAVMPGETEDDAEAAQRIADAINPRDAVILVSASGSTPYAVEAAQRARAIGATTICI
ANNAGTPLLGLANIAICLATPAEVLAGSTRMGAGTAQKAALNTMSTVMGLALGHVHDGMMVNVRADNAKLRARAVGMIAI
IANVSETRAEHCLATAENEVKPAVLLAAGASDLNDAMARLSRTDGILRPALAELMGRR

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=237, Percent_Identity=34.1772151898734, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30459; Mature: 30459

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRQTEQLHMAAKGLDALPMTDAALILARAHRDALDAVTSCATELACAGERMADVIKSG
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTLHYVAAGSSGLMAMADACELAGTFGIDLAQITIHMAGGIPTDAVMPGETEDDAEAAQR
CCEEEEEECCCCHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCCCCCCCCHHHHHHH
IADAINPRDAVILVSASGSTPYAVEAAQRARAIGATTICIANNAGTPLLGLANIAICLAT
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCC
PAEVLAGSTRMGAGTAQKAALNTMSTVMGLALGHVHDGMMVNVRADNAKLRARAVGMIAI
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHE
IANVSETRAEHCLATAENEVKPAVLLAAGASDLNDAMARLSRTDGILRPALAELMGRR
ECCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLQRQTEQLHMAAKGLDALPMTDAALILARAHRDALDAVTSCATELACAGERMADVIKSG
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTLHYVAAGSSGLMAMADACELAGTFGIDLAQITIHMAGGIPTDAVMPGETEDDAEAAQR
CCEEEEEECCCCHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCCCCCCCCHHHHHHH
IADAINPRDAVILVSASGSTPYAVEAAQRARAIGATTICIANNAGTPLLGLANIAICLAT
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCC
PAEVLAGSTRMGAGTAQKAALNTMSTVMGLALGHVHDGMMVNVRADNAKLRARAVGMIAI
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHE
IANVSETRAEHCLATAENEVKPAVLLAAGASDLNDAMARLSRTDGILRPALAELMGRR
ECCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA