Click here to switch to the map view.

The map label for this gene is coaX

Identifier: 89053689

GI number: 89053689

Start: 1158338

End: 1159117

Strand: Direct

Name: coaX

Synonym: Jann_1198

Alternate gene names: 89053689

Gene position: 1158338-1159117 (Clockwise)

Preceding gene: 89053688

Following gene: 89053690

Centisome position: 26.83

GC content: 58.59

Gene sequence:

>780_bases
ATGCTTCTTTGCATCGATTGCGGCAACACCAACACGGTTTTCTCCATCTGGGATGGCGAGAGCTGGCTGTGCACCATGCG
CACCTCCACCCATCATTCGCGGACGGCGGACGCCTATTTCACCTGGTTCTCGACATTATTGGGGCATTACGGCATCGACC
CGCAGATTGACGATGTCATCATCTCCTCCACCGTGCCGCGCGTTGTGTTCAACCTGCGGGTCTTTTGCGACCGCTTCTTC
AACCTACGCCCTCTCGTGGTGGGCAAGCCCGATTGTGCCCTGCCGATGGAGCCGCGGGTGGATTTTGGCACCGGTGTTGG
ACCGGACCGTCTGGCCAATGCCGTTGGGGCCTTCGCGCGGCATGGTGGCGATTGCGTCGTGGTGGATTTCGGGACGGCCA
CGAATTTTGACGTGGTGGCCGAAGATGGCGCTTACGTGGGCGGCGTGATTGCGCCCGGTGTGAACCTCAGTCTTGAGGCG
CTGGCCCTCGGCGCCGCCGCCTTGCCCCATGTCGATATCACCAAGCCAGACGCTGTGATTGGCACAAACACGGTGGCGTG
CATCCAATCGGGTGTTTTTTGGGGTTATGTCGGCCTGATCGAAGGAATAACAACGCGGATCAAGGCGGAATACGGCAAAC
CGATGAAGGTGATCGGCACGGGCGGGCTCGCCCCCTTGTTTGCGCAGGGAGAGGTGTTATTTGACACCGTCGAAGACGAT
CTGACGATGTACGGACTGACCGTCATCCATAAATACAACAAGGATAAAAACCCCTCATGA

Upstream 100 bases:

>100_bases
GACGGGCAATCTGATCCTTGAAACCGCCCATGGACCGCGCGCCATCGCAGCGGCTGATATCTACTTTTGAACCTGAGATT
ATCCTGAACGGAGGCTTTGC

Downstream 100 bases:

>100_bases
GTGACCGCAATCGCCTCATCTATCTCCCCATCGGCGGCGCGGGGGAGATTGGGATGAACTGCTATGTCTATGGCTACGGG
CCAGAAGGGCAGGAGCGGTT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLLCIDCGNTNTVFSIWDGESWLCTMRTSTHHSRTADAYFTWFSTLLGHYGIDPQIDDVIISSTVPRVVFNLRVFCDRFF
NLRPLVVGKPDCALPMEPRVDFGTGVGPDRLANAVGAFARHGGDCVVVDFGTATNFDVVAEDGAYVGGVIAPGVNLSLEA
LALGAAALPHVDITKPDAVIGTNTVACIQSGVFWGYVGLIEGITTRIKAEYGKPMKVIGTGGLAPLFAQGEVLFDTVEDD
LTMYGLTVIHKYNKDKNPS

Sequences:

>Translated_259_residues
MLLCIDCGNTNTVFSIWDGESWLCTMRTSTHHSRTADAYFTWFSTLLGHYGIDPQIDDVIISSTVPRVVFNLRVFCDRFF
NLRPLVVGKPDCALPMEPRVDFGTGVGPDRLANAVGAFARHGGDCVVVDFGTATNFDVVAEDGAYVGGVIAPGVNLSLEA
LALGAAALPHVDITKPDAVIGTNTVACIQSGVFWGYVGLIEGITTRIKAEYGKPMKVIGTGGLAPLFAQGEVLFDTVEDD
LTMYGLTVIHKYNKDKNPS
>Mature_259_residues
MLLCIDCGNTNTVFSIWDGESWLCTMRTSTHHSRTADAYFTWFSTLLGHYGIDPQIDDVIISSTVPRVVFNLRVFCDRFF
NLRPLVVGKPDCALPMEPRVDFGTGVGPDRLANAVGAFARHGGDCVVVDFGTATNFDVVAEDGAYVGGVIAPGVNLSLEA
LALGAAALPHVDITKPDAVIGTNTVACIQSGVFWGYVGLIEGITTRIKAEYGKPMKVIGTGGLAPLFAQGEVLFDTVEDD
LTMYGLTVIHKYNKDKNPS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_JANSC (Q28T47)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_509140.1
- ProteinModelPortal:   Q28T47
- SMR:   Q28T47
- STRING:   Q28T47
- GeneID:   3933642
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1198
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   JSP290400:JANN_1198-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27810; Mature: 27810

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLCIDCGNTNTVFSIWDGESWLCTMRTSTHHSRTADAYFTWFSTLLGHYGIDPQIDDVI
CEEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEE
ISSTVPRVVFNLRVFCDRFFNLRPLVVGKPDCALPMEPRVDFGTGVGPDRLANAVGAFAR
ECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HGGDCVVVDFGTATNFDVVAEDGAYVGGVIAPGVNLSLEALALGAAALPHVDITKPDAVI
CCCCEEEEECCCCCCCEEEECCCCEECCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
GTNTVACIQSGVFWGYVGLIEGITTRIKAEYGKPMKVIGTGGLAPLFAQGEVLFDTVEDD
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEHHCC
LTMYGLTVIHKYNKDKNPS
HHHHHEEEEEEECCCCCCC
>Mature Secondary Structure
MLLCIDCGNTNTVFSIWDGESWLCTMRTSTHHSRTADAYFTWFSTLLGHYGIDPQIDDVI
CEEEEEECCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEE
ISSTVPRVVFNLRVFCDRFFNLRPLVVGKPDCALPMEPRVDFGTGVGPDRLANAVGAFAR
ECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HGGDCVVVDFGTATNFDVVAEDGAYVGGVIAPGVNLSLEALALGAAALPHVDITKPDAVI
CCCCEEEEECCCCCCCEEEECCCCEECCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
GTNTVACIQSGVFWGYVGLIEGITTRIKAEYGKPMKVIGTGGLAPLFAQGEVLFDTVEDD
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEHHCC
LTMYGLTVIHKYNKDKNPS
HHHHHEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA