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The map label for this gene is hbpA [H]

Identifier: 89053568

GI number: 89053568

Start: 1038768

End: 1040336

Strand: Reverse

Name: hbpA [H]

Synonym: Jann_1077

Alternate gene names: 89053568

Gene position: 1040336-1038768 (Counterclockwise)

Preceding gene: 89053569

Following gene: 89053567

Centisome position: 24.09

GC content: 61.89

Gene sequence:

>1569_bases
ATGACTTTACGCAACCTGATGGCCATCACGCTTCTTGCCGGCTCGCTGGCGCTGCCTGCCGCAGCCCAGGAGCGCCCGGA
TCTGGTCATCGCCGTCGACAACCTCTGGCCAACGATGGATCCGGTTATTGGCATTTCAACGACCGGTGCCCGCGTGCACA
CGAACATCTTTGATACCCTGGTGCGTCGGAACCGCTGGGAAGATCCCGATGGCACGGAACTCGTGCCCTGGCTTGCCGAA
AGCTGGCAGCAGCTGTCGCCGAATGTCTGGGAGTTCACGCTGCGCGACGGCGTCCCCTTCCACGACGGCCACATCATGGA
TGCCGAAGATGTCGCGTTCTCGTTGTCGGCAGAACGGCTCTGGGGCGATGAACCCCTTGCCCCGCGCGGCACCCGCTACA
CGCGCGGCTTTGTGCGGGTGGAGGCGACCGGCCCGCTGACCGTCGAAGTGGAAACCAGCTTCCCCGATCCGAACCTGCCG
TTCCGCATGGTCACGCCCATCGGCTTTGTCCTGCCGCAGCATTATTATGAGGAGGTCGGAACAGAAGCCTTCGGGCAGAT
GCCGATGGGCACCGGCCCGTACCGGATGACCGCGTTTGACCCCTCCGTCGCCGTAGAGGCGGTGGCCTTTGACGATTACT
GGGCCGGAGAGCCGCCCGCCGCCACGCTGCGCTTCGAGATCGTGCCCGAGTTCTCCACCCGGTTCGCGGGCCTTGTGGCG
GGCGAATATGACGTCGTCGTCAGTGTGCCGTCCGATCAGGTCGATGTGCTCGACGGCACCGACGGCGTGACGGTGCTGGA
GAAGGGGATCGAGAATTATCCGATGTTCGCCTTCAACATGCTTGAGACCGACGCGCTGCCCGACAACCCGCTGACGGATG
TGAACCTGCGCCGCGCCATTGTGGCCGGTGTGGACCGCGACGCGATTGCAGCGGCGATCTGGGGCGACGCAACCTTCGTG
CCGACACCCTTCAACTTCCCGGAATATGGCGATTATTTCGATCCGGACCGCGAACGCGCTGTCCCGTTTGATCCCGCACA
GGCCGCCGAATACCTGGCCGCCAGCGACTATGACGGCGAAGAGCTGATCTGGCACATCACCCGGGGCTTCTACCCGAATT
ACGAGATCGCGGCGGAGTTCATGGTGGAGCAATGGGCCGAGATCGGGATCAATGTGCGCATCGAGTTGAAGGACAATTTC
TCACTCGCCTATGAACGCCCGTTCCACTTCCTCAACATGTCGATGAGCTCCGAGTTTTCCGGCGATCCCTATCGCCCGCT
CTGGATGGATTGGGGCCCTCTGTCGAGCCGGTTCCGCGCCTCGCACCGGACCTGGGACATGACGGAAGAGTTTGTGACCC
TTGGCGAAGCGTTTGAACAGACACAGGATTTTGAGGGACGCTATCAGGCCTATCTGGATCTGGTCGCGGAATGGGAACGC
GTCACGCCCGGCATGTATATGTGGCGCAACGTGGTCAGCTACGCGATCAACGAAGACCTGCAATGGGATCCCGGCAATTC
CGCCGTCACCATCTTCGATCACCTCTATATGACTGGCTATGATGGGTGA

Upstream 100 bases:

>100_bases
ACCTGCAAAACGCCCGCGATTACACGTTCCGCCACCTCAAGGGGGACGGGACCCACACGACGTCACCACAACACCAAGAT
ACATCCACGGGAGCTATGAC

Downstream 100 bases:

>100_bases
GCCGTCGCCCGGGGCGGCGCCCTTATCTGCGCCGCTCCTCTCCCTGAATAACCTGACCGTGGCGCTGCCATCGGGTGGCG
ACCGGCCCGAGGCGGTGTCT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MTLRNLMAITLLAGSLALPAAAQERPDLVIAVDNLWPTMDPVIGISTTGARVHTNIFDTLVRRNRWEDPDGTELVPWLAE
SWQQLSPNVWEFTLRDGVPFHDGHIMDAEDVAFSLSAERLWGDEPLAPRGTRYTRGFVRVEATGPLTVEVETSFPDPNLP
FRMVTPIGFVLPQHYYEEVGTEAFGQMPMGTGPYRMTAFDPSVAVEAVAFDDYWAGEPPAATLRFEIVPEFSTRFAGLVA
GEYDVVVSVPSDQVDVLDGTDGVTVLEKGIENYPMFAFNMLETDALPDNPLTDVNLRRAIVAGVDRDAIAAAIWGDATFV
PTPFNFPEYGDYFDPDRERAVPFDPAQAAEYLAASDYDGEELIWHITRGFYPNYEIAAEFMVEQWAEIGINVRIELKDNF
SLAYERPFHFLNMSMSSEFSGDPYRPLWMDWGPLSSRFRASHRTWDMTEEFVTLGEAFEQTQDFEGRYQAYLDLVAEWER
VTPGMYMWRNVVSYAINEDLQWDPGNSAVTIFDHLYMTGYDG

Sequences:

>Translated_522_residues
MTLRNLMAITLLAGSLALPAAAQERPDLVIAVDNLWPTMDPVIGISTTGARVHTNIFDTLVRRNRWEDPDGTELVPWLAE
SWQQLSPNVWEFTLRDGVPFHDGHIMDAEDVAFSLSAERLWGDEPLAPRGTRYTRGFVRVEATGPLTVEVETSFPDPNLP
FRMVTPIGFVLPQHYYEEVGTEAFGQMPMGTGPYRMTAFDPSVAVEAVAFDDYWAGEPPAATLRFEIVPEFSTRFAGLVA
GEYDVVVSVPSDQVDVLDGTDGVTVLEKGIENYPMFAFNMLETDALPDNPLTDVNLRRAIVAGVDRDAIAAAIWGDATFV
PTPFNFPEYGDYFDPDRERAVPFDPAQAAEYLAASDYDGEELIWHITRGFYPNYEIAAEFMVEQWAEIGINVRIELKDNF
SLAYERPFHFLNMSMSSEFSGDPYRPLWMDWGPLSSRFRASHRTWDMTEEFVTLGEAFEQTQDFEGRYQAYLDLVAEWER
VTPGMYMWRNVVSYAINEDLQWDPGNSAVTIFDHLYMTGYDG
>Mature_521_residues
TLRNLMAITLLAGSLALPAAAQERPDLVIAVDNLWPTMDPVIGISTTGARVHTNIFDTLVRRNRWEDPDGTELVPWLAES
WQQLSPNVWEFTLRDGVPFHDGHIMDAEDVAFSLSAERLWGDEPLAPRGTRYTRGFVRVEATGPLTVEVETSFPDPNLPF
RMVTPIGFVLPQHYYEEVGTEAFGQMPMGTGPYRMTAFDPSVAVEAVAFDDYWAGEPPAATLRFEIVPEFSTRFAGLVAG
EYDVVVSVPSDQVDVLDGTDGVTVLEKGIENYPMFAFNMLETDALPDNPLTDVNLRRAIVAGVDRDAIAAAIWGDATFVP
TPFNFPEYGDYFDPDRERAVPFDPAQAAEYLAASDYDGEELIWHITRGFYPNYEIAAEFMVEQWAEIGINVRIELKDNFS
LAYERPFHFLNMSMSSEFSGDPYRPLWMDWGPLSSRFRASHRTWDMTEEFVTLGEAFEQTQDFEGRYQAYLDLVAEWERV
TPGMYMWRNVVSYAINEDLQWDPGNSAVTIFDHLYMTGYDG

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=346, Percent_Identity=24.5664739884393, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787052, Length=411, Percent_Identity=23.3576642335766, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787551, Length=323, Percent_Identity=22.2910216718266, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787762, Length=545, Percent_Identity=22.3853211009174, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786256, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789887, Length=362, Percent_Identity=23.7569060773481, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58999; Mature: 58868

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRNLMAITLLAGSLALPAAAQERPDLVIAVDNLWPTMDPVIGISTTGARVHTNIFDTL
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEHHHHHHH
VRRNRWEDPDGTELVPWLAESWQQLSPNVWEFTLRDGVPFHDGHIMDAEDVAFSLSAERL
HHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECHHHHEEEEEHHHH
WGDEPLAPRGTRYTRGFVRVEATGPLTVEVETSFPDPNLPFRMVTPIGFVLPQHYYEEVG
CCCCCCCCCCCCEECEEEEEEECCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHC
TEAFGQMPMGTGPYRMTAFDPSVAVEAVAFDDYWAGEPPAATLRFEIVPEFSTRFAGLVA
HHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHEEE
GEYDVVVSVPSDQVDVLDGTDGVTVLEKGIENYPMFAFNMLETDALPDNPLTDVNLRRAI
CCEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
VAGVDRDAIAAAIWGDATFVPTPFNFPEYGDYFDPDRERAVPFDPAQAAEYLAASDYDGE
HHCCCHHHEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCH
ELIWHITRGFYPNYEIAAEFMVEQWAEIGINVRIELKDNFSLAYERPFHFLNMSMSSEFS
HEEEEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCEEEEEECCCCCCC
GDPYRPLWMDWGPLSSRFRASHRTWDMTEEFVTLGEAFEQTQDFEGRYQAYLDLVAEWER
CCCCCCCEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VTPGMYMWRNVVSYAINEDLQWDPGNSAVTIFDHLYMTGYDG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCC
>Mature Secondary Structure 
TLRNLMAITLLAGSLALPAAAQERPDLVIAVDNLWPTMDPVIGISTTGARVHTNIFDTL
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEHHHHHHH
VRRNRWEDPDGTELVPWLAESWQQLSPNVWEFTLRDGVPFHDGHIMDAEDVAFSLSAERL
HHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECHHHHEEEEEHHHH
WGDEPLAPRGTRYTRGFVRVEATGPLTVEVETSFPDPNLPFRMVTPIGFVLPQHYYEEVG
CCCCCCCCCCCCEECEEEEEEECCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHC
TEAFGQMPMGTGPYRMTAFDPSVAVEAVAFDDYWAGEPPAATLRFEIVPEFSTRFAGLVA
HHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHEEE
GEYDVVVSVPSDQVDVLDGTDGVTVLEKGIENYPMFAFNMLETDALPDNPLTDVNLRRAI
CCEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
VAGVDRDAIAAAIWGDATFVPTPFNFPEYGDYFDPDRERAVPFDPAQAAEYLAASDYDGE
HHCCCHHHEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCH
ELIWHITRGFYPNYEIAAEFMVEQWAEIGINVRIELKDNFSLAYERPFHFLNMSMSSEFS
HEEEEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCEEEEEECCCCCCC
GDPYRPLWMDWGPLSSRFRASHRTWDMTEEFVTLGEAFEQTQDFEGRYQAYLDLVAEWER
CCCCCCCEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VTPGMYMWRNVVSYAINEDLQWDPGNSAVTIFDHLYMTGYDG
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]