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The map label for this gene is rpoC

Identifier: 89053060

GI number: 89053060

Start: 556597

End: 560811

Strand: Direct

Name: rpoC

Synonym: Jann_0569

Alternate gene names: 89053060

Gene position: 556597-560811 (Clockwise)

Preceding gene: 161898397

Following gene: 89053061

Centisome position: 12.89

GC content: 60.33

Gene sequence:

>4215_bases
ATGAACCAGGAACTGACAAACAACCCGTTCAACCCGCTGACGCCGCCCAAGGCATTTGACGAGATCAAGGTCTCGCTCGC
TTCGCCCGAGCGGATCCTCAGCTGGTCCTACGGGGAGATCAAGAAGCCCGAGACGATCAACTACCGCACGTTCAAGCCCG
AGCGCGACGGCCTGTTCTGTGCCCGTATCTTCGGGCCGATCAAGGACTACGAATGCCTTTGCGGCAAGTATAAGCGGATG
AAGTATCGCGGCGTTGTCTGCGAGAAATGTGGTGTGGAAGTCACGCTGCAAAAGGTCCGCCGCGAGCGGATGGGGCACAT
CGAGCTGGCTGCCCCTGTGGCCCACATCTGGTTCCTCAAGTCGTTGCCGTCGCGCATCGGCCTGATGCTGGACATGACCC
TGCGCGATCTTGAGCGGATCCTGTATTTCGAGAACTATGTGGTGATCGAGCCCGGCCTGACGGACCTGACATATGGTCAG
TTGATGGGCGAAGAGGAGTTTATGGACGCGCAGGACGCCTACGGCGCCGATGCGTTCCAGGCCAACATCGGGGCTGAGGC
CATCCGTGAGATGTTGTCCCAGATTGATCTGGAATCCGAGGCCAACCAGCTGCGCGAGGACCTCAAAGAGGCCACCGGAG
AGCTGAAGCCGAAGAAGATCATCAAGCGTCTCAAGATCGTTGAATCGTTCCTCGAGTCCGGTAACCGGCCCGAGTGGATG
GTGATGACCGTTGTTCCGGTCATCCCGCCAGAACTGCGCCCGCTGGTGCCGCTGGATGGGGGCCGGTTCGCGACGTCTGA
CCTCAACGATCTGTACCGCCGCGTGATCAACCGGAACAACCGACTGAAGCGCCTGATTGAACTCCGCGCGCCGGACATCA
TCATCCGCAACGAAAAGCGGATGTTGCAGGAATCCGTGGATGCTCTGTTCGACAATGGCCGTCGGGGCCGCGTGATCACG
GGGGCCAACAAGCGCCCGCTGAAATCGCTGTCGGACATGCTGAAGGGTAAGCAGGGTCGTTTCCGTCAGAACCTTCTGGG
GAAACGCGTCGACTTCTCGGGCCGGTCCGTGATTGTGACGGGGCCGGAGCTGAAGCTGCATCAGTGCGGCTTGCCGAAGA
AGATGGCGTTGGAGCTGTTCAAGCCATTCATCTATTCGCGACTTGAGGCCAAAGGTCTGTCGTCCACCGTGAAGCAGGCG
AAGAAGCTGGTCGAAAAGGAACGTCCCGAAGTGTGGGATATCCTTGACGAGGTGATCCGGGAACATCCAGTTCTGCTGAA
CCGCGCGCCCACGCTGCACCGTCTTGGTATTCAGGCATTCGAGCCTGTGCTGATCGAAGGCAAGGCGATCCAGCTTCACC
CGCTGGTCTGTTCTGCGTTCAACGCCGATTTCGATGGCGATCAGATGGCCGTTCACGTGCCGCTGAGCCTTGAGGCACAG
TTGGAAGCCCGCGTCTTGATGATGTCGACGAACAACGTTCTGTCGCCTGCAAACGGCGCGCCGATCATCGTTCCGTCGCA
GGATATGATCCTGGGTCTCTACTACGTCACGCTGGCCCGCGAGGGCATGAAAGGCGAAGGCATGATCTTTGCCGACGTGG
ACGAAGTGCGCCACGCGCTGGACGCCGGTGAGATCCACCTGCACTCCAAGATCACGGCGCGCCTGCCGCAGATCGACGAA
GAGGGCAACGAGATCATGGTGCGGTTCGACACCACGCCCGGTCGTGTGATGTTGGGCGCGCTTCTGCCGCTTAACGCCAA
GGCGCCGTTTGATCTGGTGAACCGTCTGCTGCGCAAGAAAGAGGTGCAGCAGGTCATCGACACCGTCTACCGCTATTGCG
GCCAGAAAGAGTCGGTCATCTTCTGCGACCAGATCATGTCCATGGGCTTCAAGGAGGCGTTCAAAGCGGGCATCTCCTTC
GGCAAGGACGACATGGTCATTCCCGATACCAAATGGACGCTGGTGGAAGATGCCCGCGATCAGGTGGAGGAATTTGAGCA
GCAGTACATGGACGGCCTGATCACCCAGGGCGAAAAGTACAACAAGGTCATCGACGCGTGGTCGAAGGTGAACGACAAGG
TCACCGACGCCATGATGGGCACGATCTCGGCCTCCAAGCGGGACGAGAACGATGCCGAGATGGAGCCAAACTCGGTCTAC
ATGATGGCCCACTCCGGGGCCCGTGGATCTGTTACGCAGATGAAGCAGTTGGGCGGCATGCGCGGCCTGATGGCCAAGCC
GAACGGTGAAATCATCGAAACGCCGATCATCTCGAACTTCAAGGAGGGTCTGACCGTTCTTGAATACTTCAACTCCACCC
ACGGCGCCCGGAAGGGTCTGTCGGACACGGCGTTGAAGACGGCGAACTCCGGCTATCTGACGCGACGTCTGGTGGACGTG
GCCCAGGACTGCATCGTGCGTATGGACGATTGCGGGACCGAGAACACGATCAAGGCAGAGGCGGCCGTGAACGACGGTGA
AGTCGTGGCATCCCTGGCTGAGCGTATTCTGGGCCGGACGGCTGGCGAAGACGTGTTCATTCCGGGCACCGATGAGATCA
TCGTCGCCAAGGGCGAGCTGATCGACGAACGCAAGGCCGACGCGGTGGAAGCCGCTGGTGTCACGACGATGCAGATGCGG
TCCCCGCTGACCTGTGAGGCGGAAGAGGGCGTCTGCGCGACCTGCTACGGTCGGGATCTGGCACGCGGCACGAAGGTGAA
CACCGGCGAAGCCGTGGGCATCATCGCGGCGCAGTCGATTGGTGAGCCGGGCACACAGCTGACGATGCGGACGTTCCACA
TCGGCGGCGTGGCCCAGGGTGGTCAGCAGTCCTTTCAGGAGGTCAACGTCGACGGCAAAGTGGAATTCCGCAACGCCAAC
CTGCTGAAGAACGCCAATGGCGAAAGCGTTGTCATGGGCCGGAACATGGTCCTTGCGATCATGGACGATCAGGGCAGCGA
ACGCGCGTCGTTCAAGCTGGGTTACGGCACCAACGTTCTTGTCGAAGACGGCAAGAAAGTTGTCCGTGGCGACCGTCTGT
TCGAATGGGATCCCTATACCCTGCCGATCATCGCGGAAGCGGCGGGAACGGCGAAGTTCGTGGATCTTGTCTCGGGCATT
TCGATCCGCGATGAAACCGACGATGCGACGGGCATGACCCAAAAGATCGTCTCGGATTGGCGCACGGCCCCCAAGGGCAA
TGAGCTGAAGCCCGAGATCATCATCGCGGGCGAAGATGGCGAGCCGATGCGCAACGATCAGGGCAACCCGGTCACCTACA
CGATGTCGGTGGATGCGATCCTGTCGATCGAAGAAGGCCAAACGGTCAAAGCCGGTGACGTGATTGCGCGTATCCCGCGG
GAAGGTGCGAAGACGAAGGACATCACCGGTGGTCTGCCGCGTGTGGCCGAACTGTTTGAAGCCCGGCGTCCCAAGGACCA
CGCGATCATCGCGGAAATCGATGGCTACGTGAAATTCGGCCGTGACTTCAAGAACAAGCGCCGGATCGGCATTGTTCCTG
CGGACGAAAGTCTGGAGCCCGTGGAATACATGGTGCCCAAGGGCAAGCACATCCCCGTGGCCGAAGGCGATTTCGTTCAG
GTCGGGGATTACATCATGGACGGCAACCCCGCGCCGCACGACATTCTTGCCGTGTTGGGTGTTGAGGCGCTGGCCGATTA
TATGATCGACGAGGTCCAGGATGTGTACCGTCTTCAGGGCGTGAAGATTAACGATAAGCACATCGAGGTTATCGTTCGTC
AGATGCTCCAGAAGTGGGAGATCCAGGATTCGGGCGAGACCACGCTGCTCAAGGGTGAGCATGTGGATAAGGCCGAATTC
GACTCCGCCAACGCGAAGGCCGTCCGTGACGGTCGTCGTCCGGCACAGGGGGAGCCGATCTTGTTGGGCATCACCAAGGC
GTCGCTGCAAACCCGCAGCTTCATCTCTGCCGCCTCCTTCCAGGAGACGACGCGGGTGCTGACGGAAGCCTCTGTTCAGG
GCAAGAAAGACCGTCTGGTCGGCCTGAAAGAGAACGTCATCGTGGGCCGTCTGATCCCCGCAGGCACCGGTGGTGCCACG
CAGGATGTGGAGCGGATCGCCAAGGGTCGGGACCAGGTCGTCATCGACGCCGCGCAAGCGGAAGCCGAAGCCGCCGCAGC
CCTGGCCGCACCGGTCATGGAAGATGCCGCACCGGATACCGACGCCGCCGAGTAA

Upstream 100 bases:

>100_bases
ACGCCTTGATAAGTACGTCTACTTCCGGCGTCGCGATATCCGAAAGAAATTATCGGCGAGCAGACTTTTTCGTCTGTCCC
GAAGAGGGAGAGGTTTCCCA

Downstream 100 bases:

>100_bases
GGTCGTCACAGACAAATTAGGACGCGCCCCGTTGGAGACAGCGGGGCGCTTTTTTTGTGGCATTGGGCACGGATCTTGCT
ATCGTTCCTGAAATGTTCTC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1404; Mature: 1404

Protein sequence:

>1404_residues
MNQELTNNPFNPLTPPKAFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQ
LMGEEEFMDAQDAYGADAFQANIGAEAIREMLSQIDLESEANQLREDLKEATGELKPKKIIKRLKIVESFLESGNRPEWM
VMTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYVTLAREGMKGEGMIFADVDEVRHALDAGEIHLHSKITARLPQIDE
EGNEIMVRFDTTPGRVMLGALLPLNAKAPFDLVNRLLRKKEVQQVIDTVYRYCGQKESVIFCDQIMSMGFKEAFKAGISF
GKDDMVIPDTKWTLVEDARDQVEEFEQQYMDGLITQGEKYNKVIDAWSKVNDKVTDAMMGTISASKRDENDAEMEPNSVY
MMAHSGARGSVTQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVRMDDCGTENTIKAEAAVNDGEVVASLAERILGRTAGEDVFIPGTDEIIVAKGELIDERKADAVEAAGVTTMQMR
SPLTCEAEEGVCATCYGRDLARGTKVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFQEVNVDGKVEFRNAN
LLKNANGESVVMGRNMVLAIMDDQGSERASFKLGYGTNVLVEDGKKVVRGDRLFEWDPYTLPIIAEAAGTAKFVDLVSGI
SIRDETDDATGMTQKIVSDWRTAPKGNELKPEIIIAGEDGEPMRNDQGNPVTYTMSVDAILSIEEGQTVKAGDVIARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVKFGRDFKNKRRIGIVPADESLEPVEYMVPKGKHIPVAEGDFVQ
VGDYIMDGNPAPHDILAVLGVEALADYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEIQDSGETTLLKGEHVDKAEF
DSANAKAVRDGRRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDRLVGLKENVIVGRLIPAGTGGAT
QDVERIAKGRDQVVIDAAQAEAEAAAALAAPVMEDAAPDTDAAE

Sequences:

>Translated_1404_residues
MNQELTNNPFNPLTPPKAFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQ
LMGEEEFMDAQDAYGADAFQANIGAEAIREMLSQIDLESEANQLREDLKEATGELKPKKIIKRLKIVESFLESGNRPEWM
VMTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYVTLAREGMKGEGMIFADVDEVRHALDAGEIHLHSKITARLPQIDE
EGNEIMVRFDTTPGRVMLGALLPLNAKAPFDLVNRLLRKKEVQQVIDTVYRYCGQKESVIFCDQIMSMGFKEAFKAGISF
GKDDMVIPDTKWTLVEDARDQVEEFEQQYMDGLITQGEKYNKVIDAWSKVNDKVTDAMMGTISASKRDENDAEMEPNSVY
MMAHSGARGSVTQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVRMDDCGTENTIKAEAAVNDGEVVASLAERILGRTAGEDVFIPGTDEIIVAKGELIDERKADAVEAAGVTTMQMR
SPLTCEAEEGVCATCYGRDLARGTKVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFQEVNVDGKVEFRNAN
LLKNANGESVVMGRNMVLAIMDDQGSERASFKLGYGTNVLVEDGKKVVRGDRLFEWDPYTLPIIAEAAGTAKFVDLVSGI
SIRDETDDATGMTQKIVSDWRTAPKGNELKPEIIIAGEDGEPMRNDQGNPVTYTMSVDAILSIEEGQTVKAGDVIARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVKFGRDFKNKRRIGIVPADESLEPVEYMVPKGKHIPVAEGDFVQ
VGDYIMDGNPAPHDILAVLGVEALADYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEIQDSGETTLLKGEHVDKAEF
DSANAKAVRDGRRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDRLVGLKENVIVGRLIPAGTGGAT
QDVERIAKGRDQVVIDAAQAEAEAAAALAAPVMEDAAPDTDAAE
>Mature_1404_residues
MNQELTNNPFNPLTPPKAFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQ
LMGEEEFMDAQDAYGADAFQANIGAEAIREMLSQIDLESEANQLREDLKEATGELKPKKIIKRLKIVESFLESGNRPEWM
VMTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYVTLAREGMKGEGMIFADVDEVRHALDAGEIHLHSKITARLPQIDE
EGNEIMVRFDTTPGRVMLGALLPLNAKAPFDLVNRLLRKKEVQQVIDTVYRYCGQKESVIFCDQIMSMGFKEAFKAGISF
GKDDMVIPDTKWTLVEDARDQVEEFEQQYMDGLITQGEKYNKVIDAWSKVNDKVTDAMMGTISASKRDENDAEMEPNSVY
MMAHSGARGSVTQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVRMDDCGTENTIKAEAAVNDGEVVASLAERILGRTAGEDVFIPGTDEIIVAKGELIDERKADAVEAAGVTTMQMR
SPLTCEAEEGVCATCYGRDLARGTKVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFQEVNVDGKVEFRNAN
LLKNANGESVVMGRNMVLAIMDDQGSERASFKLGYGTNVLVEDGKKVVRGDRLFEWDPYTLPIIAEAAGTAKFVDLVSGI
SIRDETDDATGMTQKIVSDWRTAPKGNELKPEIIIAGEDGEPMRNDQGNPVTYTMSVDAILSIEEGQTVKAGDVIARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVKFGRDFKNKRRIGIVPADESLEPVEYMVPKGKHIPVAEGDFVQ
VGDYIMDGNPAPHDILAVLGVEALADYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEIQDSGETTLLKGEHVDKAEF
DSANAKAVRDGRRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDRLVGLKENVIVGRLIPAGTGGAT
QDVERIAKGRDQVVIDAAQAEAEAAAALAAPVMEDAAPDTDAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=948, Percent_Identity=25.3164556962025, Blast_Score=188, Evalue=4e-47,
Organism=Homo sapiens, GI39725938, Length=309, Percent_Identity=32.0388349514563, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI103471997, Length=249, Percent_Identity=29.3172690763052, Blast_Score=92, Evalue=3e-18,
Organism=Escherichia coli, GI2367335, Length=1394, Percent_Identity=59.038737446198, Blast_Score=1650, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=570, Percent_Identity=25.9649122807018, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=32.1428571428571, Blast_Score=142, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324690, Length=597, Percent_Identity=26.465661641541, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320061, Length=549, Percent_Identity=26.775956284153, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17530899, Length=834, Percent_Identity=25.5395683453237, Blast_Score=173, Evalue=9e-43,
Organism=Drosophila melanogaster, GI281360912, Length=336, Percent_Identity=30.3571428571429, Blast_Score=134, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17647875, Length=351, Percent_Identity=25.3561253561254, Blast_Score=100, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_JANSC (Q28UX6)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508511.1
- ProteinModelPortal:   Q28UX6
- STRING:   Q28UX6
- GeneID:   3933011
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0569
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   IQAFHPV
- PhylomeDB:   Q28UX6
- ProtClustDB:   PRK00566
- BioCyc:   JSP290400:JANN_0569-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155207; Mature: 155207

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQELTNNPFNPLTPPKAFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFC
CCCCCCCCCCCCCCCCCCHHHHEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEE
ARIFGPIKDYECLCGKYKRMKYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
SLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQLMGEEEFMDAQDAYGADAFQ
HHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCHHHHCCCHHCCCCCHHH
ANIGAEAIREMLSQIDLESEANQLREDLKEATGELKPKKIIKRLKIVESFLESGNRPEWM
HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VMTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKR
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHH
MLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVT
HHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEE
GPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQAKKLVEKERPEVWDILDEVIR
CCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
HCCEEECCCCCHHHHCHHHCCCEEECCCEEEEEHHHHHHCCCCCCCCCEEEEECCEECCC
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYVTLAREGMKGEGMIFADVDEVRHAL
CCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHH
DAGEIHLHSKITARLPQIDEEGNEIMVRFDTTPGRVMLGALLPLNAKAPFDLVNRLLRKK
CCCCEEEECHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
EVQQVIDTVYRYCGQKESVIFCDQIMSMGFKEAFKAGISFGKDDMVIPDTKWTLVEDARD
HHHHHHHHHHHHHCCCCCEEEHHHHHHCCHHHHHHHHCCCCCCCEECCCCCCHHHHHHHH
QVEEFEQQYMDGLITQGEKYNKVIDAWSKVNDKVTDAMMGTISASKRDENDAEMEPNSVY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
MMAHSGARGSVTQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGL
EEEECCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHCCC
SDTALKTANSGYLTRRLVDVAQDCIVRMDDCGTENTIKAEAAVNDGEVVASLAERILGRT
CHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
AGEDVFIPGTDEIIVAKGELIDERKADAVEAAGVTTMQMRSPLTCEAEEGVCATCYGRDL
CCCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEHHCCCCCEECCCCEEEEECCCHH
ARGTKVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFQEVNVDGKVEFRNAN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCEEEECCCC
LLKNANGESVVMGRNMVLAIMDDQGSERASFKLGYGTNVLVEDGKKVVRGDRLFEWDPYT
EEECCCCCEEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCHHHCCCCEEECCCCE
LPIIAEAAGTAKFVDLVSGISIRDETDDATGMTQKIVSDWRTAPKGNELKPEIIIAGEDG
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
EPMRNDQGNPVTYTMSVDAILSIEEGQTVKAGDVIARIPREGAKTKDITGGLPRVAELFE
CCCCCCCCCCEEEEEEEEEEEEECCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGYVKFGRDFKNKRRIGIVPADESLEPVEYMVPKGKHIPVAEGDFVQ
HCCCCCCEEEEEECCHHHHCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCCEEE
VGDYIMDGNPAPHDILAVLGVEALADYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWE
ECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCC
IQDSGETTLLKGEHVDKAEFDSANAKAVRDGRRPAQGEPILLGITKASLQTRSFISAASF
CCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QETTRVLTEASVQGKKDRLVGLKENVIVGRLIPAGTGGATQDVERIAKGRDQVVIDAAQA
HHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHH
EAEAAAALAAPVMEDAAPDTDAAE
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNQELTNNPFNPLTPPKAFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFC
CCCCCCCCCCCCCCCCCCHHHHEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEE
ARIFGPIKDYECLCGKYKRMKYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
SLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQLMGEEEFMDAQDAYGADAFQ
HHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCHHHHCCCHHCCCCCHHH
ANIGAEAIREMLSQIDLESEANQLREDLKEATGELKPKKIIKRLKIVESFLESGNRPEWM
HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VMTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKR
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHH
MLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVT
HHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEE
GPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQAKKLVEKERPEVWDILDEVIR
CCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
HCCEEECCCCCHHHHCHHHCCCEEECCCEEEEEHHHHHHCCCCCCCCCEEEEECCEECCC
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYVTLAREGMKGEGMIFADVDEVRHAL
CCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHH
DAGEIHLHSKITARLPQIDEEGNEIMVRFDTTPGRVMLGALLPLNAKAPFDLVNRLLRKK
CCCCEEEECHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
EVQQVIDTVYRYCGQKESVIFCDQIMSMGFKEAFKAGISFGKDDMVIPDTKWTLVEDARD
HHHHHHHHHHHHHCCCCCEEEHHHHHHCCHHHHHHHHCCCCCCCEECCCCCCHHHHHHHH
QVEEFEQQYMDGLITQGEKYNKVIDAWSKVNDKVTDAMMGTISASKRDENDAEMEPNSVY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
MMAHSGARGSVTQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGL
EEEECCCCCCHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHCCC
SDTALKTANSGYLTRRLVDVAQDCIVRMDDCGTENTIKAEAAVNDGEVVASLAERILGRT
CHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
AGEDVFIPGTDEIIVAKGELIDERKADAVEAAGVTTMQMRSPLTCEAEEGVCATCYGRDL
CCCCEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEHHCCCCCEECCCCEEEEECCCHH
ARGTKVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFQEVNVDGKVEFRNAN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCEEEECCCC
LLKNANGESVVMGRNMVLAIMDDQGSERASFKLGYGTNVLVEDGKKVVRGDRLFEWDPYT
EEECCCCCEEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCHHHCCCCEEECCCCE
LPIIAEAAGTAKFVDLVSGISIRDETDDATGMTQKIVSDWRTAPKGNELKPEIIIAGEDG
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
EPMRNDQGNPVTYTMSVDAILSIEEGQTVKAGDVIARIPREGAKTKDITGGLPRVAELFE
CCCCCCCCCCEEEEEEEEEEEEECCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGYVKFGRDFKNKRRIGIVPADESLEPVEYMVPKGKHIPVAEGDFVQ
HCCCCCCEEEEEECCHHHHCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCCEEE
VGDYIMDGNPAPHDILAVLGVEALADYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWE
ECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCC
IQDSGETTLLKGEHVDKAEFDSANAKAVRDGRRPAQGEPILLGITKASLQTRSFISAASF
CCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QETTRVLTEASVQGKKDRLVGLKENVIVGRLIPAGTGGATQDVERIAKGRDQVVIDAAQA
HHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHH
EAEAAAALAAPVMEDAAPDTDAAE
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA