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The map label for this gene is ybbO [H]

Identifier: 89053042

GI number: 89053042

Start: 538707

End: 539534

Strand: Reverse

Name: ybbO [H]

Synonym: Jann_0551

Alternate gene names: 89053042

Gene position: 539534-538707 (Counterclockwise)

Preceding gene: 89053043

Following gene: 89053041

Centisome position: 12.5

GC content: 64.25

Gene sequence:

>828_bases
GTGACACGATCCATCCTGATCACCGGCAGCTCCTCCGGCATTGGCCACGTGGCCGCACACACCCTGCACGCCCGGGGCTG
GCGCGTCTTTGCCTGCGTTCGTCGCGATGAAGATCTCGCGCGGCTGGAGACCGAGGGGCTGGAAAGCGGCCTTCTGGATG
TCAGCGATGCCGACAGCATTGAGGCCGGGCTCGCCGACGTGCTGGACCGGACCGGCGGCACGCTTGACGCGCTCTTCAAC
AATGCGGGCTTCGGGCTGCCTGGTCTGGTGGAAGATCTGCCCACCGATGCCCTGCGCGCGACGTTTGAGACCAATGTCTT
CGGCCTGCACCATCTGACCCGCGCGGTGATCCCCACGATGCGCCGACAGGGCCACGGACGAATTGTCCAGCATTCGTCGG
GCTTTGGGCGCCATGTGATGAAATGGCGGGGCGCCTACAATGCCTCCAAACACGCGGTGGAGGGGCTGACGGATACATTG
CGGCTGGAGATGCGCGGAACCGGCATCCATATCTCGACCCTCAATACCGGGCCCGTCACCTCAAAATTCCGCCTGAATTC
CATTCCGCAGTTCGAGCGCTGGATCGAGTGGGAGGCATCCGCCGATCCGGATCGCTACAAGAGAGAGTTGTTCCGTCACC
TCTACGAGGATACCGGCCCTGCTCCGTTCCAGCGCGAGCCCGATGCTGTCGTCAAACGCCTGATCCACGCGATTGAGGCC
GACGCCCCGCGCCCACGCTATCACATCACACCCGCCGTCCACTTCGCCGAGGCTCTGCGCCGCACCTTGCCTCAGCGGCT
GCTGGACGCGATTGCGGTCAGACTTTGA

Upstream 100 bases:

>100_bases
CGGCCCAGTTTCTTGAACCTACCAACTGACCCCTTGGCGGGCTTGCGCGGGTCGGCGTCCCTGTCCTAGTGATGCAGACA
CAGCACGCGAAGGGGTTTTC

Downstream 100 bases:

>100_bases
ACCGCAGCCTCTAGCAATCCGCGCCACGCCTGCTACCTCCTGCCAAACACTTTGGAGACGACATGACAGACGACCCCCTT
CTTATCGCCGGACTTGTGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTRSILITGSSSGIGHVAAHTLHARGWRVFACVRRDEDLARLETEGLESGLLDVSDADSIEAGLADVLDRTGGTLDALFN
NAGFGLPGLVEDLPTDALRATFETNVFGLHHLTRAVIPTMRRQGHGRIVQHSSGFGRHVMKWRGAYNASKHAVEGLTDTL
RLEMRGTGIHISTLNTGPVTSKFRLNSIPQFERWIEWEASADPDRYKRELFRHLYEDTGPAPFQREPDAVVKRLIHAIEA
DAPRPRYHITPAVHFAEALRRTLPQRLLDAIAVRL

Sequences:

>Translated_275_residues
MTRSILITGSSSGIGHVAAHTLHARGWRVFACVRRDEDLARLETEGLESGLLDVSDADSIEAGLADVLDRTGGTLDALFN
NAGFGLPGLVEDLPTDALRATFETNVFGLHHLTRAVIPTMRRQGHGRIVQHSSGFGRHVMKWRGAYNASKHAVEGLTDTL
RLEMRGTGIHISTLNTGPVTSKFRLNSIPQFERWIEWEASADPDRYKRELFRHLYEDTGPAPFQREPDAVVKRLIHAIEA
DAPRPRYHITPAVHFAEALRRTLPQRLLDAIAVRL
>Mature_274_residues
TRSILITGSSSGIGHVAAHTLHARGWRVFACVRRDEDLARLETEGLESGLLDVSDADSIEAGLADVLDRTGGTLDALFNN
AGFGLPGLVEDLPTDALRATFETNVFGLHHLTRAVIPTMRRQGHGRIVQHSSGFGRHVMKWRGAYNASKHAVEGLTDTLR
LEMRGTGIHISTLNTGPVTSKFRLNSIPQFERWIEWEASADPDRYKRELFRHLYEDTGPAPFQREPDAVVKRLIHAIEAD
APRPRYHITPAVHFAEALRRTLPQRLLDAIAVRL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=260, Percent_Identity=32.6923076923077, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI20149619, Length=216, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI223718074, Length=275, Percent_Identity=30.9090909090909, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI22507405, Length=258, Percent_Identity=32.9457364341085, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19743808, Length=282, Percent_Identity=31.9148936170213, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI40548397, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI214010158, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI214010156, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI22758144, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI44680136, Length=265, Percent_Identity=28.6792452830189, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI44680133, Length=265, Percent_Identity=28.6792452830189, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI17738292, Length=265, Percent_Identity=28.6792452830189, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=34.3589743589744, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI150247226, Length=284, Percent_Identity=31.6901408450704, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI157739938, Length=267, Percent_Identity=27.7153558052434, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=29.4444444444444, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI119392083, Length=200, Percent_Identity=31.5, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4504503, Length=299, Percent_Identity=25.4180602006689, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI50726952, Length=279, Percent_Identity=29.3906810035842, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI32483357, Length=185, Percent_Identity=30.8108108108108, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=272, Percent_Identity=34.9264705882353, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=32.0652173913043, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787335, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082100, Length=219, Percent_Identity=27.8538812785388, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=190, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557780, Length=263, Percent_Identity=27.3764258555133, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=280, Percent_Identity=26.0714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=261, Percent_Identity=26.0536398467433, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=230, Percent_Identity=30, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=29.9465240641711, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=268, Percent_Identity=27.6119402985075, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI116007238, Length=175, Percent_Identity=32.5714285714286, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356301, Length=182, Percent_Identity=28.021978021978, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651139, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580925, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641232, Length=204, Percent_Identity=28.921568627451, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=33.5051546391753, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648693, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355889, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641388, Length=213, Percent_Identity=30.5164319248826, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30601; Mature: 30470

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSILITGSSSGIGHVAAHTLHARGWRVFACVRRDEDLARLETEGLESGLLDVSDADSI
CCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHH
EAGLADVLDRTGGTLDALFNNAGFGLPGLVEDLPTDALRATFETNVFGLHHLTRAVIPTM
HHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
RRQGHGRIVQHSSGFGRHVMKWRGAYNASKHAVEGLTDTLRLEMRGTGIHISTLNTGPVT
HHCCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCEEEEEECCCCCCC
SKFRLNSIPQFERWIEWEASADPDRYKRELFRHLYEDTGPAPFQREPDAVVKRLIHAIEA
CCEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
DAPRPRYHITPAVHFAEALRRTLPQRLLDAIAVRL
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRSILITGSSSGIGHVAAHTLHARGWRVFACVRRDEDLARLETEGLESGLLDVSDADSI
CCEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHH
EAGLADVLDRTGGTLDALFNNAGFGLPGLVEDLPTDALRATFETNVFGLHHLTRAVIPTM
HHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHH
RRQGHGRIVQHSSGFGRHVMKWRGAYNASKHAVEGLTDTLRLEMRGTGIHISTLNTGPVT
HHCCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCEEEEEECCCCCCC
SKFRLNSIPQFERWIEWEASADPDRYKRELFRHLYEDTGPAPFQREPDAVVKRLIHAIEA
CCEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
DAPRPRYHITPAVHFAEALRRTLPQRLLDAIAVRL
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]