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The map label for this gene is chvG [H]

Identifier: 89053028

GI number: 89053028

Start: 527405

End: 529129

Strand: Direct

Name: chvG [H]

Synonym: Jann_0537

Alternate gene names: 89053028

Gene position: 527405-529129 (Clockwise)

Preceding gene: 89053027

Following gene: 89053029

Centisome position: 12.21

GC content: 61.62

Gene sequence:

>1725_bases
GTGCCAGCTGACGTCTCTATGACCAACCGCCGCGCTGCTGAGCGGGCGGATATCGTATTGGGCGAGGATTGGGATCGCCC
CCAATCCGGCGTAGAATCCGAGCTGCGCGCCGCAAGGTCGCGTCGCTCCTGGATCTCTCTCAACTCCTCCCCGCTGGCAC
GCAAGATCATCCTGTTCAACCTGATCGCGATCATGGTTCTGGGCATGGTCTTTCTGTGGCTCAATCCTGTGCGCGACAGC
CTCGTCATCCAACGTGAGCGGGCGCTGGCCAGCGAGGCGCAGCTGATGTCGGATATTTTCGAGGCGCATTTGCCCGCCTC
GGCCCCTGCCAATCTCGTTACCGGCGACGGGATCGATGCCGAGGGCGTCCTGTCGCGCATTGGCGTGCCGGATGGCATGG
AAGTATTTGTCTTCTCTACCGAGGGCGTGCCTGTGACGTCGACCCAGGACATTGCCCGCAGCGGTGTGCGCCCGGTGCGG
GGGTTGGAACACCAGGCGCAAGAGACGCTTCTGATCACGGATTTCCTCGTGTCGATCTACGATGGCCTCTCTGGCTTTCT
GGGCAACGGTCCCCGGCCCGACGCCACGCAAAACGGGCCCGAGGCCCATGCCGATCTGGTTGCCGCCGCCATGGGCGGTG
CCACCATTCTGCAACGCGGCACCAACCTGAGCGGTACCGTTCATGCCGCGTCCTCCCCCATTGAGGGAGCGGGTGGAATT
GTAGGCGTTATCGTCGTGACCACCGCCGCGGGAGAGATTGACCAACTGGTCCGCGTGGAACAGGAACAACTGTTGCAGAT
GTTCGTCGTGGCCCTTCTGGTCTCCATCGTGCTGTCCCTCGTGCTGGCGTCGACGATCGCCAACCCGCTTGCCGATCTGT
CTGCCGCCGCTGAGTTGGGGCGAGACAAGAACGCCCGCAAAATGTCTCCGACCCGCGTCCGCATCCCTGACTTGACCGGC
AGGCCGGATGAGATCGGTCGCCTGTCCGGTGCGCTACGGGGCATGGTCGCGGCGCTGTATGACCGGATCGATTCCAACGA
GCAGTTCGCGGCTGACGTCAGCCATGAAATCAAGAACCCCCTCGCGTCGCTCCGCTCGGCCGTGGGCACGCTGGAATTCG
CCAAGACCGATGATCAGCGCAAGCGGCTAATTGATGTGATCGAGCATGACGTCCATCGGCTCGACCGTCTGGTCAGCGAT
ATTTCCAACGCTTCCCGCCTCGACAGTGAGCTGGTGAAGGAGGAGGAGGAAGAGTTCAACCTTGTCCAGACGCTCGAAAA
CCTCTCGCAGTACCATTCGGAAGAAGCCGGAAAGCAGGGGATCGAATTCATCACGGACCTGCCCACGGAACGCATTGATA
TCGCAGGCCTCGAAGGGCGCCTGGCCCAGGTCTTTGTGAACCTGTTGAGCAACGCCATTTCCTTCTGCGAAGATGGCGAC
GCGGTGCGGCTCTGGACCCGGCGGCGTGAAAATCGCGTGTTGATCGTGGTAGAAGACACCGGTCCAGGTATCCCTGAGGA
GGCTTTGACCAAAGTGTTCAACCGCTTTTACTCGGAACGGCCCGCCAATCAGTTTGGCAACAATTCCGGTCTGGGCCTGG
CGATCTCCAAACAGATCGTGGAGGCCCATGGTGGTGTCATCTGGGCAGAGAACATTCGCCCGACGGAGGCCGACGTGACG
TCGGAGCCTCTGGGCGCTAGGTTTGTCGTTGGCCTGCCGATCTGA

Upstream 100 bases:

>100_bases
GCGGCTGCGCAAGAAGATGCGGTCCGTCGACAATGATTTCTCAGCGATTGAGACACTCTACGGCATTGGCTACCGCTACA
ACGAAGAATAGGGGCGGACT

Downstream 100 bases:

>100_bases
GCCATGACGCCTCCGGCTGAGCCGCTGGCCGAGCGGGCAAGCGCGCGCGACGGCACAAGGCTTTTCTTCCACGCATCCGC
AATCGTTGTTGCGGGCAAAG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MPADVSMTNRRAAERADIVLGEDWDRPQSGVESELRAARSRRSWISLNSSPLARKIILFNLIAIMVLGMVFLWLNPVRDS
LVIQRERALASEAQLMSDIFEAHLPASAPANLVTGDGIDAEGVLSRIGVPDGMEVFVFSTEGVPVTSTQDIARSGVRPVR
GLEHQAQETLLITDFLVSIYDGLSGFLGNGPRPDATQNGPEAHADLVAAAMGGATILQRGTNLSGTVHAASSPIEGAGGI
VGVIVVTTAAGEIDQLVRVEQEQLLQMFVVALLVSIVLSLVLASTIANPLADLSAAAELGRDKNARKMSPTRVRIPDLTG
RPDEIGRLSGALRGMVAALYDRIDSNEQFAADVSHEIKNPLASLRSAVGTLEFAKTDDQRKRLIDVIEHDVHRLDRLVSD
ISNASRLDSELVKEEEEEFNLVQTLENLSQYHSEEAGKQGIEFITDLPTERIDIAGLEGRLAQVFVNLLSNAISFCEDGD
AVRLWTRRRENRVLIVVEDTGPGIPEEALTKVFNRFYSERPANQFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEADVT
SEPLGARFVVGLPI

Sequences:

>Translated_574_residues
MPADVSMTNRRAAERADIVLGEDWDRPQSGVESELRAARSRRSWISLNSSPLARKIILFNLIAIMVLGMVFLWLNPVRDS
LVIQRERALASEAQLMSDIFEAHLPASAPANLVTGDGIDAEGVLSRIGVPDGMEVFVFSTEGVPVTSTQDIARSGVRPVR
GLEHQAQETLLITDFLVSIYDGLSGFLGNGPRPDATQNGPEAHADLVAAAMGGATILQRGTNLSGTVHAASSPIEGAGGI
VGVIVVTTAAGEIDQLVRVEQEQLLQMFVVALLVSIVLSLVLASTIANPLADLSAAAELGRDKNARKMSPTRVRIPDLTG
RPDEIGRLSGALRGMVAALYDRIDSNEQFAADVSHEIKNPLASLRSAVGTLEFAKTDDQRKRLIDVIEHDVHRLDRLVSD
ISNASRLDSELVKEEEEEFNLVQTLENLSQYHSEEAGKQGIEFITDLPTERIDIAGLEGRLAQVFVNLLSNAISFCEDGD
AVRLWTRRRENRVLIVVEDTGPGIPEEALTKVFNRFYSERPANQFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEADVT
SEPLGARFVVGLPI
>Mature_573_residues
PADVSMTNRRAAERADIVLGEDWDRPQSGVESELRAARSRRSWISLNSSPLARKIILFNLIAIMVLGMVFLWLNPVRDSL
VIQRERALASEAQLMSDIFEAHLPASAPANLVTGDGIDAEGVLSRIGVPDGMEVFVFSTEGVPVTSTQDIARSGVRPVRG
LEHQAQETLLITDFLVSIYDGLSGFLGNGPRPDATQNGPEAHADLVAAAMGGATILQRGTNLSGTVHAASSPIEGAGGIV
GVIVVTTAAGEIDQLVRVEQEQLLQMFVVALLVSIVLSLVLASTIANPLADLSAAAELGRDKNARKMSPTRVRIPDLTGR
PDEIGRLSGALRGMVAALYDRIDSNEQFAADVSHEIKNPLASLRSAVGTLEFAKTDDQRKRLIDVIEHDVHRLDRLVSDI
SNASRLDSELVKEEEEEFNLVQTLENLSQYHSEEAGKQGIEFITDLPTERIDIAGLEGRLAQVFVNLLSNAISFCEDGDA
VRLWTRRRENRVLIVVEDTGPGIPEEALTKVFNRFYSERPANQFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEADVTS
EPLGARFVVGLPI

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=32.9004329004329, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786783, Length=259, Percent_Identity=30.1158301158301, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790861, Length=344, Percent_Identity=25.8720930232558, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789403, Length=280, Percent_Identity=29.6428571428571, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=314, Percent_Identity=27.7070063694268, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=27.7153558052434, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=29.4372294372294, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=206, Percent_Identity=25.7281553398058, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787374, Length=285, Percent_Identity=25.6140350877193, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=26.3888888888889, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=339, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=287, Percent_Identity=25.7839721254355, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=362, Percent_Identity=26.7955801104972, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62127; Mature: 61996

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADVSMTNRRAAERADIVLGEDWDRPQSGVESELRAARSRRSWISLNSSPLARKIILFN
CCCCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
LIAIMVLGMVFLWLNPVRDSLVIQRERALASEAQLMSDIFEAHLPASAPANLVTGDGIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCH
EGVLSRIGVPDGMEVFVFSTEGVPVTSTQDIARSGVRPVRGLEHQAQETLLITDFLVSIY
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DGLSGFLGNGPRPDATQNGPEAHADLVAAAMGGATILQRGTNLSGTVHAASSPIEGAGGI
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCEEECCCCCCCCCCCE
VGVIVVTTAAGEIDQLVRVEQEQLLQMFVVALLVSIVLSLVLASTIANPLADLSAAAELG
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDKNARKMSPTRVRIPDLTGRPDEIGRLSGALRGMVAALYDRIDSNEQFAADVSHEIKNP
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LASLRSAVGTLEFAKTDDQRKRLIDVIEHDVHRLDRLVSDISNASRLDSELVKEEEEEFN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQTLENLSQYHSEEAGKQGIEFITDLPTERIDIAGLEGRLAQVFVNLLSNAISFCEDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCC
AVRLWTRRRENRVLIVVEDTGPGIPEEALTKVFNRFYSERPANQFGNNSGLGLAISKQIV
EEEHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHH
EAHGGVIWAENIRPTEADVTSEPLGARFVVGLPI
HHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
PADVSMTNRRAAERADIVLGEDWDRPQSGVESELRAARSRRSWISLNSSPLARKIILFN
CCCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
LIAIMVLGMVFLWLNPVRDSLVIQRERALASEAQLMSDIFEAHLPASAPANLVTGDGIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCH
EGVLSRIGVPDGMEVFVFSTEGVPVTSTQDIARSGVRPVRGLEHQAQETLLITDFLVSIY
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DGLSGFLGNGPRPDATQNGPEAHADLVAAAMGGATILQRGTNLSGTVHAASSPIEGAGGI
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCEEECCCCCCCCCCCE
VGVIVVTTAAGEIDQLVRVEQEQLLQMFVVALLVSIVLSLVLASTIANPLADLSAAAELG
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDKNARKMSPTRVRIPDLTGRPDEIGRLSGALRGMVAALYDRIDSNEQFAADVSHEIKNP
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LASLRSAVGTLEFAKTDDQRKRLIDVIEHDVHRLDRLVSDISNASRLDSELVKEEEEEFN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQTLENLSQYHSEEAGKQGIEFITDLPTERIDIAGLEGRLAQVFVNLLSNAISFCEDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCC
AVRLWTRRRENRVLIVVEDTGPGIPEEALTKVFNRFYSERPANQFGNNSGLGLAISKQIV
EEEHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHH
EAHGGVIWAENIRPTEADVTSEPLGARFVVGLPI
HHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194 [H]