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The map label for this gene is acpS

Identifier: 89053011

GI number: 89053011

Start: 512611

End: 513063

Strand: Direct

Name: acpS

Synonym: Jann_0520

Alternate gene names: 89053011

Gene position: 512611-513063 (Clockwise)

Preceding gene: 89053010

Following gene: 89053012

Centisome position: 11.87

GC content: 66.45

Gene sequence:

>453_bases
TTGATTCTCGGCATCGGAACGGATCTCGCGAATATCGAACGGATCGAGGGGACGCTGGAGCGGTTCGGCGACCGCTTCCG
CAACCGCGTCTTCACGGACCGCGAACAAGCCCGGGCGGAGCGGATGCCTGAACCTGCCGCCGTCTATGCCAAGCGATGGG
CGGCGAAAGAGGCGTGTTCAAAGGCACTGGGCACCGGTTTGCGCATGGGGATCGCCTGGAAGGACATGTCGGTGCGCAAC
CTGCGGACGGGACAGCCGGTGATGGAGGTCACGGGATGGGCGCGGGAGCGGTTGGACCAGATGACGCCCGACGGCTACGG
CGCGGTGATCCATGTGACCCTGACCGACGATCACCCCTGGGCCCAGGCCATGGTGGTGATCGAGGCGCTGACGCCCGAGG
AGGCAGAGTTACGCCCGGATCTGGGGCCTGCGGCGCGCCGGACAATGAGCTGA

Upstream 100 bases:

>100_bases
TGCGGGGCCTTTACACGCGGGCACGACGGGGGATTGAAGCGGCGACGGCGGGCCTTTTCGCGCTTGCCGGGCTGCGCTTG
CTGACATGGCGGGGCGCACC

Downstream 100 bases:

>100_bases
CGTGGATCAGCCTGCCAGTTCGCGTCAACGGTGTGTTTCCGCCAAGAAAATTGCGCAGCGACGCCCGGTTTGGGCCGTTT
GCTTGACTTGGCCAATGGGT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MILGIGTDLANIERIEGTLERFGDRFRNRVFTDREQARAERMPEPAAVYAKRWAAKEACSKALGTGLRMGIAWKDMSVRN
LRTGQPVMEVTGWARERLDQMTPDGYGAVIHVTLTDDHPWAQAMVVIEALTPEEAELRPDLGPAARRTMS

Sequences:

>Translated_150_residues
MILGIGTDLANIERIEGTLERFGDRFRNRVFTDREQARAERMPEPAAVYAKRWAAKEACSKALGTGLRMGIAWKDMSVRN
LRTGQPVMEVTGWARERLDQMTPDGYGAVIHVTLTDDHPWAQAMVVIEALTPEEAELRPDLGPAARRTMS
>Mature_150_residues
MILGIGTDLANIERIEGTLERFGDRFRNRVFTDREQARAERMPEPAAVYAKRWAAKEACSKALGTGLRMGIAWKDMSVRN
LRTGQPVMEVTGWARERLDQMTPDGYGAVIHVTLTDDHPWAQAMVVIEALTPEEAELRPDLGPAARRTMS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=40.625, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_JANSC (Q28V25)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508462.1
- ProteinModelPortal:   Q28V25
- SMR:   Q28V25
- STRING:   Q28V25
- GeneID:   3932961
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0520
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   AYAKRWA
- PhylomeDB:   Q28V25
- ProtClustDB:   PRK00070
- BioCyc:   JSP290400:JANN_0520-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 16809; Mature: 16809

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGTDLANIERIEGTLERFGDRFRNRVFTDREQARAERMPEPAAVYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
KALGTGLRMGIAWKDMSVRNLRTGQPVMEVTGWARERLDQMTPDGYGAVIHVTLTDDHPW
HHHCCCHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
AQAMVVIEALTPEEAELRPDLGPAARRTMS
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MILGIGTDLANIERIEGTLERFGDRFRNRVFTDREQARAERMPEPAAVYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
KALGTGLRMGIAWKDMSVRNLRTGQPVMEVTGWARERLDQMTPDGYGAVIHVTLTDDHPW
HHHCCCHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
AQAMVVIEALTPEEAELRPDLGPAARRTMS
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA