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The map label for this gene is plsC [C]

Identifier: 89052967

GI number: 89052967

Start: 473395

End: 474120

Strand: Reverse

Name: plsC [C]

Synonym: Jann_0476

Alternate gene names: 89052967

Gene position: 474120-473395 (Counterclockwise)

Preceding gene: 89052968

Following gene: 89052966

Centisome position: 10.98

GC content: 61.85

Gene sequence:

>726_bases
GTGCAGACGATCCGTTCCTTCCTTCACATCGTGCAGATGTATGTTGCGATGCTGATCATCGCCGTGGTCTTTTTCCCTTG
GGCTTTGTTCAGCCCGCGCGGGGCCCATGCGGCCTGTCACACCTATTGCGCTTGGGTCTTCTGGACCCTGCGCTGGATGG
TTGGGCTGCGCGTCGAGGTGCGGGGCACCCCTCCTACGGATGAAGTCCTTGTGGCCGCGAAGCATCAGAGCTTTCTGGAT
GTCATGGTCATTTACCACGCCGTCCCGCGGGGCAAGTTCATCATGAAGCGAGAGCTGATGTTCGCCCCTTTCCTGGGACA
ATACGGGCTGCGCATTGGCTGTGTTCCCGTGAACCGAGGCAAACGCGGCGCGGCGATCAAGAAAATGCTGGAGGATGTGC
GCAGCGGAAAGCAGCAGGGCGGGCAGCTGATCATCTATCCCCAAGGCACCCGCATAGCGCCCGGCGTCTCGGCCCCCTAC
AAGGCGGGCACTGGCGCGCTCTATGCGCAAATGGGCCAACCCTGCGTGCCTGTGGCCACCAATATCGGGGTCTTTTGGCC
CAAGACGGGCATCACCCGCAAACCCGGCGTGGCAGTGGTCGACTTCCTGCCCCGGATCGAACCCGGGATGGAGGCGAAAC
CGTTCCTGGACCGGCTGGAACATGACATTGAGACCGCCAGCAACGCGCTGCTGGACGAAGCGGGGTTTCGGAGGGATGAG
ACATGA

Upstream 100 bases:

>100_bases
AAGGGTGGTTTTGGCCGCTGTTGATCCCGGGTCTCGCCGCCACGACGGCGTTCATCGCCACACGCTTCGCCGCGTTCCGG
ACGCTCAGGGGGCTCCAATA

Downstream 100 bases:

>100_bases
AGACGATCACTGATATCGCGGAGTTGGAGGCGCTTTATGATGCGGCCGTTCCCACATCGCTGACGAAAGTCGTACCCGCC
CTAACGCCGCTCTACCGGCA

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MQTIRSFLHIVQMYVAMLIIAVVFFPWALFSPRGAHAACHTYCAWVFWTLRWMVGLRVEVRGTPPTDEVLVAAKHQSFLD
VMVIYHAVPRGKFIMKRELMFAPFLGQYGLRIGCVPVNRGKRGAAIKKMLEDVRSGKQQGGQLIIYPQGTRIAPGVSAPY
KAGTGALYAQMGQPCVPVATNIGVFWPKTGITRKPGVAVVDFLPRIEPGMEAKPFLDRLEHDIETASNALLDEAGFRRDE
T

Sequences:

>Translated_241_residues
MQTIRSFLHIVQMYVAMLIIAVVFFPWALFSPRGAHAACHTYCAWVFWTLRWMVGLRVEVRGTPPTDEVLVAAKHQSFLD
VMVIYHAVPRGKFIMKRELMFAPFLGQYGLRIGCVPVNRGKRGAAIKKMLEDVRSGKQQGGQLIIYPQGTRIAPGVSAPY
KAGTGALYAQMGQPCVPVATNIGVFWPKTGITRKPGVAVVDFLPRIEPGMEAKPFLDRLEHDIETASNALLDEAGFRRDE
T
>Mature_241_residues
MQTIRSFLHIVQMYVAMLIIAVVFFPWALFSPRGAHAACHTYCAWVFWTLRWMVGLRVEVRGTPPTDEVLVAAKHQSFLD
VMVIYHAVPRGKFIMKRELMFAPFLGQYGLRIGCVPVNRGKRGAAIKKMLEDVRSGKQQGGQLIIYPQGTRIAPGVSAPY
KAGTGALYAQMGQPCVPVATNIGVFWPKTGITRKPGVAVVDFLPRIEPGMEAKPFLDRLEHDIETASNALLDEAGFRRDE
T

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=218, Percent_Identity=28.8990825688073, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15100175, Length=218, Percent_Identity=28.8990825688073, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789395, Length=219, Percent_Identity=28.7671232876712, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364648, Length=225, Percent_Identity=23.5555555555556, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24582856, Length=225, Percent_Identity=23.5555555555556, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24582854, Length=225, Percent_Identity=23.5555555555556, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 26815; Mature: 26815

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIRSFLHIVQMYVAMLIIAVVFFPWALFSPRGAHAACHTYCAWVFWTLRWMVGLRVEV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
RGTPPTDEVLVAAKHQSFLDVMVIYHAVPRGKFIMKRELMFAPFLGQYGLRIGCVPVNRG
ECCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
KRGAAIKKMLEDVRSGKQQGGQLIIYPQGTRIAPGVSAPYKAGTGALYAQMGQPCVPVAT
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHCCCCCCCHHC
NIGVFWPKTGITRKPGVAVVDFLPRIEPGMEAKPFLDRLEHDIETASNALLDEAGFRRDE
CCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
T
C
>Mature Secondary Structure
MQTIRSFLHIVQMYVAMLIIAVVFFPWALFSPRGAHAACHTYCAWVFWTLRWMVGLRVEV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
RGTPPTDEVLVAAKHQSFLDVMVIYHAVPRGKFIMKRELMFAPFLGQYGLRIGCVPVNRG
ECCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCC
KRGAAIKKMLEDVRSGKQQGGQLIIYPQGTRIAPGVSAPYKAGTGALYAQMGQPCVPVAT
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHCCCCCCCHHC
NIGVFWPKTGITRKPGVAVVDFLPRIEPGMEAKPFLDRLEHDIETASNALLDEAGFRRDE
CCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA