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The map label for this gene is 89052929

Identifier: 89052929

GI number: 89052929

Start: 442912

End: 443208

Strand: Direct

Name: 89052929

Synonym: Jann_0438

Alternate gene names: NA

Gene position: 442912-443208 (Clockwise)

Preceding gene: 89052928

Following gene: 89052931

Centisome position: 10.26

GC content: 59.93

Gene sequence:

>297_bases
ATGGCCGAGAAACTGGACGACGCCGCGCGGGCGAAGGCTGTGGCGAGCCTAGCTGACAGCGGATGGGAAGACGTGCAGGG
GCGCGACGCAATCCACAAGACGTTTGTCTTCAAGAATTTCACCCGCGCCTTTGGCTGGATGACACAAGTGGCGATCGTGG
CGGAAAAGATGGACCATCATCCAGAGTGGTCGAACGTCTACAAAACGGTCGAGGTCACGCTGGCGACGCATGATGTCGGC
GGCTTGTCCGAATTGGACGTGACGCTGGCCCAGAAAATGGACCGCCTCGCGCAGTAG

Upstream 100 bases:

>100_bases
GGCGGTATCTTGAGGCCGAGCGGGAGGCCGTGGACGAGGAGATTGAAGTGCTGACAGGATACGGCCCGTTCAAGCGGGCT
TAGGTGGAGGAACAGGAGTA

Downstream 100 bases:

>100_bases
CCGCGCGAGGCGTCCCAGTGACAACGCGGTTCAGATGACAGCCAACAGCGACTCGCCGGCTGACACTTCGCAGGTGCCTG
CGTTGTCTTCTTCATGCAGG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MAEKLDDAARAKAVASLADSGWEDVQGRDAIHKTFVFKNFTRAFGWMTQVAIVAEKMDHHPEWSNVYKTVEVTLATHDVG
GLSELDVTLAQKMDRLAQ

Sequences:

>Translated_98_residues
MAEKLDDAARAKAVASLADSGWEDVQGRDAIHKTFVFKNFTRAFGWMTQVAIVAEKMDHHPEWSNVYKTVEVTLATHDVG
GLSELDVTLAQKMDRLAQ
>Mature_97_residues
AEKLDDAARAKAVASLADSGWEDVQGRDAIHKTFVFKNFTRAFGWMTQVAIVAEKMDHHPEWSNVYKTVEVTLATHDVGG
LSELDVTLAQKMDRLAQ

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=96, Percent_Identity=51.0416666666667, Blast_Score=110, Evalue=3e-25,
Organism=Homo sapiens, GI134133240, Length=94, Percent_Identity=47.8723404255319, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI115533705, Length=94, Percent_Identity=52.1276595744681, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549100, Length=98, Percent_Identity=51.0204081632653, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_JANSC (Q28VA7)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508380.1
- ProteinModelPortal:   Q28VA7
- SMR:   Q28VA7
- STRING:   Q28VA7
- GeneID:   3932879
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0438
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   GQERIDS
- BioCyc:   JSP290400:JANN_0438-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 10918; Mature: 10787

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKLDDAARAKAVASLADSGWEDVQGRDAIHKTFVFKNFTRAFGWMTQVAIVAEKMDHH
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEWSNVYKTVEVTLATHDVGGLSELDVTLAQKMDRLAQ
CCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEKLDDAARAKAVASLADSGWEDVQGRDAIHKTFVFKNFTRAFGWMTQVAIVAEKMDHH
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEWSNVYKTVEVTLATHDVGGLSELDVTLAQKMDRLAQ
CCHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA