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The map label for this gene is map [H]

Identifier: 89052776

GI number: 89052776

Start: 290667

End: 291476

Strand: Direct

Name: map [H]

Synonym: Jann_0285

Alternate gene names: 89052776

Gene position: 290667-291476 (Clockwise)

Preceding gene: 89052775

Following gene: 89052777

Centisome position: 6.73

GC content: 60.25

Gene sequence:

>810_bases
TTGGACGATTTCAAAGGCCGACTGACAAAAGACGGCATCCGCATTCACCAGATTGTTGACTGCGCTGGTATGCACCGGGC
GGGGCGGCTTGCGGCGGACATTCTGGATCGGGTCGCACCGCTGGTGGTGCCCGGTGTCACGACCGGCACATTGGATGCGC
AGATTGAGGCCTGGGTGGACGAGGTCGGGGCCAAATCCGCGACAATCGGGTATCGCGGCTACAAGCATGCCAGCTGCATC
AGCATCAACCATGTCGTCTGCCACGGCATCCCCAGCGACAAGAAGCTGAAGGACGGCGATATCGTGAATATCGACGTGAC
GGTCATCGTCGACGGCTGGTTCGGGGATACGTCGCGGATGTTTGTGGCCGGCAATCTGCCGCGCAAGGCGGAGCGGTTGA
TCCAGGTCACGCATGATGCCCTGTTCAAGGGAATTGAGGCCGTGAAACCCGGCAAGACCTTCGGCGATATCGGTCACGCG
ATCCAGGCCTATGTGGAGGCGCAGCGCATGTCCGTTGTGCGCGACTTCTGTGGCCATGGCTTGGGGCAGGTGTTTCACGC
GCCTCCCAACGTGTTGCATTACGGTCGGCCGGGCACTGGCCCCACGCTCGAAGAAGGCATGTTCTTCACCATTGAGCCGA
TGGTGAACCTGGGTCGCCCTGAAACGAAGGTTCTGTCCGATGACTGGACGGCCGTGACCCGCGATAAATCCCTCAGCGCA
CAGTTTGAGCATTCCATTGGCGTGACGGCGGATGGGTTTGAGATCTTTACGCTGTCGCCCACCGGTCGGTTCCATCCAAC
CTATGGCTGA

Upstream 100 bases:

>100_bases
GGACACAACCTGCGCTCTCAGGCACTGGCAATTTCTCCACGTCCGCCCTATTTATCGCGAGAACACGCTTGTCCGCCCGC
GCGGGTGATGGAGACTTCCC

Downstream 100 bases:

>100_bases
GATGTGATGTGTTATGCGGGCGCTCGTTAACCCGCCGTTTCAGTCAAGCTGGGTATCCATCGCTAACGATCCGTTAACCA
TTTGACGGCAAGCTTGTGGG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MDDFKGRLTKDGIRIHQIVDCAGMHRAGRLAADILDRVAPLVVPGVTTGTLDAQIEAWVDEVGAKSATIGYRGYKHASCI
SINHVVCHGIPSDKKLKDGDIVNIDVTVIVDGWFGDTSRMFVAGNLPRKAERLIQVTHDALFKGIEAVKPGKTFGDIGHA
IQAYVEAQRMSVVRDFCGHGLGQVFHAPPNVLHYGRPGTGPTLEEGMFFTIEPMVNLGRPETKVLSDDWTAVTRDKSLSA
QFEHSIGVTADGFEIFTLSPTGRFHPTYG

Sequences:

>Translated_269_residues
MDDFKGRLTKDGIRIHQIVDCAGMHRAGRLAADILDRVAPLVVPGVTTGTLDAQIEAWVDEVGAKSATIGYRGYKHASCI
SINHVVCHGIPSDKKLKDGDIVNIDVTVIVDGWFGDTSRMFVAGNLPRKAERLIQVTHDALFKGIEAVKPGKTFGDIGHA
IQAYVEAQRMSVVRDFCGHGLGQVFHAPPNVLHYGRPGTGPTLEEGMFFTIEPMVNLGRPETKVLSDDWTAVTRDKSLSA
QFEHSIGVTADGFEIFTLSPTGRFHPTYG
>Mature_269_residues
MDDFKGRLTKDGIRIHQIVDCAGMHRAGRLAADILDRVAPLVVPGVTTGTLDAQIEAWVDEVGAKSATIGYRGYKHASCI
SINHVVCHGIPSDKKLKDGDIVNIDVTVIVDGWFGDTSRMFVAGNLPRKAERLIQVTHDALFKGIEAVKPGKTFGDIGHA
IQAYVEAQRMSVVRDFCGHGLGQVFHAPPNVLHYGRPGTGPTLEEGMFFTIEPMVNLGRPETKVLSDDWTAVTRDKSLSA
QFEHSIGVTADGFEIFTLSPTGRFHPTYG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=39.5918367346939, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI40385867, Length=250, Percent_Identity=38, Blast_Score=181, Evalue=4e-46,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=53.4136546184739, Blast_Score=258, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI71996291, Length=236, Percent_Identity=40.2542372881356, Blast_Score=186, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=37.5, Blast_Score=190, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21355531, Length=235, Percent_Identity=44.6808510638298, Blast_Score=208, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=41.3934426229508, Blast_Score=193, Evalue=8e-50,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29250; Mature: 29250

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDFKGRLTKDGIRIHQIVDCAGMHRAGRLAADILDRVAPLVVPGVTTGTLDAQIEAWVD
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHH
EVGAKSATIGYRGYKHASCISINHVVCHGIPSDKKLKDGDIVNIDVTVIVDGWFGDTSRM
HHCCCCEEECCCCCCCCEEEEECEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCE
FVAGNLPRKAERLIQVTHDALFKGIEAVKPGKTFGDIGHAIQAYVEAQRMSVVRDFCGHG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LGQVFHAPPNVLHYGRPGTGPTLEEGMFFTIEPMVNLGRPETKVLSDDWTAVTRDKSLSA
HHHHHCCCCCEEECCCCCCCCCHHCCEEEEEECHHCCCCCCCEEECCCCCEEECCCCCCH
QFEHSIGVTADGFEIFTLSPTGRFHPTYG
HHHHCCCCEECCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDDFKGRLTKDGIRIHQIVDCAGMHRAGRLAADILDRVAPLVVPGVTTGTLDAQIEAWVD
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHH
EVGAKSATIGYRGYKHASCISINHVVCHGIPSDKKLKDGDIVNIDVTVIVDGWFGDTSRM
HHCCCCEEECCCCCCCCEEEEECEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCE
FVAGNLPRKAERLIQVTHDALFKGIEAVKPGKTFGDIGHAIQAYVEAQRMSVVRDFCGHG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LGQVFHAPPNVLHYGRPGTGPTLEEGMFFTIEPMVNLGRPETKVLSDDWTAVTRDKSLSA
HHHHHCCCCCEEECCCCCCCCCHHCCEEEEEECHHCCCCCCCEEECCCCCEEECCCCCCH
QFEHSIGVTADGFEIFTLSPTGRFHPTYG
HHHHCCCCEECCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]