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The map label for this gene is coaD [H]

Identifier: 88658395

GI number: 88658395

Start: 746771

End: 747268

Strand: Reverse

Name: coaD [H]

Synonym: ECH_0737

Alternate gene names: 88658395

Gene position: 747268-746771 (Counterclockwise)

Preceding gene: 88657812

Following gene: 88658631

Centisome position: 63.53

GC content: 29.52

Gene sequence:

>498_bases
GTGAAAATAGGCATATATCCTGGTACTTTTGATCCTATTACTTTTGGCCATATTGATATTATAAAGCGAGCTTATAATTT
GGTTGATAAGTTAGTAATAGGTGTTGCTAGAAGTTGTACAAAAAAAACTATTTTTTCTGCTGAAGTTCGTGCGGAACTTA
TACAGCATGAGATAAAATTGCTAGGTATGGCAGTAAATACTGTAATTTTTGATGGATTATTGGTATATTTTGCTAAAGAA
AATAATGCATCTGTTATAATTAGGGGATTAAGAGCTGTATCTGATTTTGATTATGAATTTCAAATGAGTTGGGTAAATTA
TAAACTTACTTCTCAGATTGAAACTATCTTTTTACCAGCTTCAGAAGATACTCAATTTATTTCTTCAAGTTTTGTCAAAG
AAATAGCACGATTAAATGGAGATGTAAGTGTTTTTGTGCCTGTGAATGTACAAGAATGTTTGAAAAATTTCTATCAAAAG
TCTAATGTTAATGGTTAA

Upstream 100 bases:

>100_bases
AAATTATATATTGTAAATATTATCTGTTCAAGTAAAAATATAAGCTTAAAATAATTAAGATGTTGTGATATAATAAATTT
TTATTCATTGATAATTTTCT

Downstream 100 bases:

>100_bases
TAATTTTTAACATGATTTTTACTTTTTAGCTACTGTATTATGTTAGAAAGTGAAACATTTAATTATCCTTTTCTATGAAA
GAGTAGCAACAAATTTCTAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKIGIYPGTFDPITFGHIDIIKRAYNLVDKLVIGVARSCTKKTIFSAEVRAELIQHEIKLLGMAVNTVIFDGLLVYFAKE
NNASVIIRGLRAVSDFDYEFQMSWVNYKLTSQIETIFLPASEDTQFISSSFVKEIARLNGDVSVFVPVNVQECLKNFYQK
SNVNG

Sequences:

>Translated_165_residues
MKIGIYPGTFDPITFGHIDIIKRAYNLVDKLVIGVARSCTKKTIFSAEVRAELIQHEIKLLGMAVNTVIFDGLLVYFAKE
NNASVIIRGLRAVSDFDYEFQMSWVNYKLTSQIETIFLPASEDTQFISSSFVKEIARLNGDVSVFVPVNVQECLKNFYQK
SNVNG
>Mature_165_residues
MKIGIYPGTFDPITFGHIDIIKRAYNLVDKLVIGVARSCTKKTIFSAEVRAELIQHEIKLLGMAVNTVIFDGLLVYFAKE
NNASVIIRGLRAVSDFDYEFQMSWVNYKLTSQIETIFLPASEDTQFISSSFVKEIARLNGDVSVFVPVNVQECLKNFYQK
SNVNG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=153, Percent_Identity=48.3660130718954, Blast_Score=153, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18597; Mature: 18597

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIYPGTFDPITFGHIDIIKRAYNLVDKLVIGVARSCTKKTIFSAEVRAELIQHEIKL
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMAVNTVIFDGLLVYFAKENNASVIIRGLRAVSDFDYEFQMSWVNYKLTSQIETIFLPA
HHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHCCCCCEEEEEEEEEEECCCEEEEEEEC
SEDTQFISSSFVKEIARLNGDVSVFVPVNVQECLKNFYQKSNVNG
CCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIGIYPGTFDPITFGHIDIIKRAYNLVDKLVIGVARSCTKKTIFSAEVRAELIQHEIKL
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMAVNTVIFDGLLVYFAKENNASVIIRGLRAVSDFDYEFQMSWVNYKLTSQIETIFLPA
HHHHHHHHHHHHHHEEEECCCCCEEEEEHHHHHCCCCCEEEEEEEEEEECCCEEEEEEEC
SEDTQFISSSFVKEIARLNGDVSVFVPVNVQECLKNFYQKSNVNG
CCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA