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The map label for this gene is qor [H]

Identifier: 88658375

GI number: 88658375

Start: 379241

End: 380215

Strand: Direct

Name: qor [H]

Synonym: ECH_0385

Alternate gene names: 88658375

Gene position: 379241-380215 (Clockwise)

Preceding gene: 88658271

Following gene: 88657740

Centisome position: 32.24

GC content: 32.82

Gene sequence:

>975_bases
ATGGTAAAAGTTATTATTATTGATAAAACTGGTAGTGCTGAAGTTTTAAAATATGTTAATCATAATATTGGTGAACCTAA
AGATGATGAGGTATTGATAAAACATACAGCTATTGGCTTAAATCGCTACGATCTTGAGTGCCGTAATGGTATGCGTAAAA
ATAAAAAACTTCCTGCTGTTTTAGGAGTTGAGGCAGTAGGTGTTATAGAGAGATTGGGTAAAGATGTTGAAGTGTTTAAT
ATTGGTGATAGAGTAGGTTATTGTACTGTATCTGGAGGGGCTTATTCTGAAAAAAGACTTATTAAACAAAAATATTTAGT
TAGAATACCTGATGATATTACTGATCAAGTAGCAGCTGCGGTATTATTTAAAGGTATGACAGCGCATTATCTTACACACT
TAGTTTATGCTATACGTCCTAATACTTTTGCTTTAGTGCATGGAGCAACAGGTGGTGTAGGCCAAATATTATGTCAGTGG
GCTAGTTATAAAGGATGTAAAGTTATAGGTGTAATTAGTTCTGATGATAGGGCTAATATTGCCTTGCGTGCTGGATGTTC
ATATGTAGTAAATAATAATAGTAAAAATTTTGTTGAGCAGATCATGGAAATTACTCACGGTTCTGGAGTTAATGTAGTTT
ATGACTGTATAGGTGATTTAGCTAGTAAAGTATCTTTTGAATCTCTTTGTATGTTTGGTATTTATGTTTCTTATGGCCAG
ATATCAGGACCTATTTCAAATGTTAGTGCTTCTATGCTAAGTTCCAGATCATTGTTTTTTACCTCTCCTTTGGTGTTCCA
CTATAAACGTTCTAGTTTTGATTTGGCGATGACAGCTATGGAGCTTTTTGAAGTGATAAGAAGAAATTATATAAAAGTTG
GGATAAATAAGATTTATAAGTTTGGTGATATAGTAACTGCACATCAGGATTTGGAAAATAGAAAACTTACTGGTTCAAAT
ATTATTGAACTGTAG

Upstream 100 bases:

>100_bases
TGTTATTAATTAATATTGATGTCTTAAATTAAAAAGATATCATTTAGCTGTTTGATAAGTATTCTAAATGTAATTACGTT
CTATTTAATTATGTGATGTT

Downstream 100 bases:

>100_bases
ATGTTTTATAAGTGAGCAAAAAGATATTTTACCTTTTTACTATGATAAGAAAAGTTATAGTGCGTGATTAATTCAGTGAA
TATGTAATTTGCTACTTTCT

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVKVIIIDKTGSAEVLKYVNHNIGEPKDDEVLIKHTAIGLNRYDLECRNGMRKNKKLPAVLGVEAVGVIERLGKDVEVFN
IGDRVGYCTVSGGAYSEKRLIKQKYLVRIPDDITDQVAAAVLFKGMTAHYLTHLVYAIRPNTFALVHGATGGVGQILCQW
ASYKGCKVIGVISSDDRANIALRAGCSYVVNNNSKNFVEQIMEITHGSGVNVVYDCIGDLASKVSFESLCMFGIYVSYGQ
ISGPISNVSASMLSSRSLFFTSPLVFHYKRSSFDLAMTAMELFEVIRRNYIKVGINKIYKFGDIVTAHQDLENRKLTGSN
IIEL

Sequences:

>Translated_324_residues
MVKVIIIDKTGSAEVLKYVNHNIGEPKDDEVLIKHTAIGLNRYDLECRNGMRKNKKLPAVLGVEAVGVIERLGKDVEVFN
IGDRVGYCTVSGGAYSEKRLIKQKYLVRIPDDITDQVAAAVLFKGMTAHYLTHLVYAIRPNTFALVHGATGGVGQILCQW
ASYKGCKVIGVISSDDRANIALRAGCSYVVNNNSKNFVEQIMEITHGSGVNVVYDCIGDLASKVSFESLCMFGIYVSYGQ
ISGPISNVSASMLSSRSLFFTSPLVFHYKRSSFDLAMTAMELFEVIRRNYIKVGINKIYKFGDIVTAHQDLENRKLTGSN
IIEL
>Mature_324_residues
MVKVIIIDKTGSAEVLKYVNHNIGEPKDDEVLIKHTAIGLNRYDLECRNGMRKNKKLPAVLGVEAVGVIERLGKDVEVFN
IGDRVGYCTVSGGAYSEKRLIKQKYLVRIPDDITDQVAAAVLFKGMTAHYLTHLVYAIRPNTFALVHGATGGVGQILCQW
ASYKGCKVIGVISSDDRANIALRAGCSYVVNNNSKNFVEQIMEITHGSGVNVVYDCIGDLASKVSFESLCMFGIYVSYGQ
ISGPISNVSASMLSSRSLFFTSPLVFHYKRSSFDLAMTAMELFEVIRRNYIKVGINKIYKFGDIVTAHQDLENRKLTGSN
IIEL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=27.7439024390244, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=27.7439024390244, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI194239674, Length=313, Percent_Identity=24.9201277955272, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI13236495, Length=313, Percent_Identity=24.9201277955272, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI24308257, Length=241, Percent_Identity=31.5352697095436, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=30.5418719211823, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=24.1157556270096, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI28557745, Length=240, Percent_Identity=25.4166666666667, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=35.6923076923077, Blast_Score=198, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17507255, Length=326, Percent_Identity=23.9263803680982, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=326, Percent_Identity=31.2883435582822, Blast_Score=165, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35737; Mature: 35737

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVIIIDKTGSAEVLKYVNHNIGEPKDDEVLIKHTAIGLNRYDLECRNGMRKNKKLPAV
CEEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCCHH
LGVEAVGVIERLGKDVEVFNIGDRVGYCTVSGGAYSEKRLIKQKYLVRIPDDITDQVAAA
HCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHEEECCCHHHHHHHHH
VLFKGMTAHYLTHLVYAIRPNTFALVHGATGGVGQILCQWASYKGCKVIGVISSDDRANI
HHHHCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCE
ALRAGCSYVVNNNSKNFVEQIMEITHGSGVNVVYDCIGDLASKVSFESLCMFGIYVSYGQ
EEEECCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
ISGPISNVSASMLSSRSLFFTSPLVFHYKRSSFDLAMTAMELFEVIRRNYIKVGINKIYK
CCCCHHHHHHHHHCCCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGDIVTAHQDLENRKLTGSNIIEL
HHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKVIIIDKTGSAEVLKYVNHNIGEPKDDEVLIKHTAIGLNRYDLECRNGMRKNKKLPAV
CEEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCCHH
LGVEAVGVIERLGKDVEVFNIGDRVGYCTVSGGAYSEKRLIKQKYLVRIPDDITDQVAAA
HCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHEEECCCHHHHHHHHH
VLFKGMTAHYLTHLVYAIRPNTFALVHGATGGVGQILCQWASYKGCKVIGVISSDDRANI
HHHHCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCE
ALRAGCSYVVNNNSKNFVEQIMEITHGSGVNVVYDCIGDLASKVSFESLCMFGIYVSYGQ
EEEECCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
ISGPISNVSASMLSSRSLFFTSPLVFHYKRSSFDLAMTAMELFEVIRRNYIKVGINKIYK
CCCCHHHHHHHHHCCCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGDIVTAHQDLENRKLTGSNIIEL
HHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]