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The map label for this gene is era [H]

Identifier: 88658308

GI number: 88658308

Start: 455262

End: 456152

Strand: Direct

Name: era [H]

Synonym: ECH_0476

Alternate gene names: 88658308

Gene position: 455262-456152 (Clockwise)

Preceding gene: 88658536

Following gene: 88657802

Centisome position: 38.7

GC content: 30.42

Gene sequence:

>891_bases
ATGGATCATATAAGTAAAAAATGTTCTATGAATGCTATAGTTGGTACAACTAATGCAGGAAAGTCAACATTAATTAATAT
GCTAGTAGGACAAAAGGTTGCAGCAGTGACGCCAAAGGTGCAAACTACTAGAGTTAGGATGCATGCTGTATTGAATAATG
AGAATGTTCAATTGATATTTATAGATACACCAGGTATCTTTTCTCCGAAGACAAAATTAGAAAAGTTTATTGTAAAGCAT
GCTTGGATGTCTCTTAAAGGTATTGAAAATGTAATACTGTTGCTTGATGTAAAAAATTATTTGAATAAGCATATTGAGAA
GATTATTAGTAGAATCAAGCAATCTAATATCAATGCTATCTTAGTAGTGAATAAGATTGATACAGTTCCTACATCTTCAG
TTGATAAAGCAATAGAACATATGTATTCACTACATAGTTTTAGTAAAACTTTTACTATATCAGCATTGCATGATATTGGG
TTAAGTCGTTTAGTTGATTATCTATGTGAAATTTCACCTAATGGTCCTTGGTTATATCCTGAAGATCAGATTAGTGATGC
ACCATTAAAATTTTTTATGGCTGAAATTACACGGGAAAAGTTATTTTTGTCTTTACACCATGAATTACCTTATTCTTTAT
CTGTAGTGACTGAAGCATTAGAAGAAAAAGAAGATGGAAGTTTAGTTGTTAAGCAGGTAATATATGTAACTAAAGATAGT
CATAGGACTATCATTTTAGGCAAAAAAGGAGAGATGATAAAGAAAATTAGCATGGAATCTAGATCTGATCTTGCAAAGAT
CCTTGATTTAAAGATACATCTTTTCTTATTTGTAAAAGTTAGAGAATTTTGGCAAAACCATTTAGATGAATGTGTAGGGT
ATGTTGAATAG

Upstream 100 bases:

>100_bases
GTAGCATTAAGAGTTTCAAGTATATACTGTATAATTTTTATGTTTTTTGTAAATGTAGGAATGTACTGTATATTTAATTA
CTTAGTATTAGCAAGGGAAT

Downstream 100 bases:

>100_bases
TTTATTGGTTTTTGATATAGAAACAATTCCAGATGTGGATGTTTGCCGTAATCTCCTCAGTGATTTTGATGAGACAGTTG
AGTTGAGTGAGAAAAGGGAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDHISKKCSMNAIVGTTNAGKSTLINMLVGQKVAAVTPKVQTTRVRMHAVLNNENVQLIFIDTPGIFSPKTKLEKFIVKH
AWMSLKGIENVILLLDVKNYLNKHIEKIISRIKQSNINAILVVNKIDTVPTSSVDKAIEHMYSLHSFSKTFTISALHDIG
LSRLVDYLCEISPNGPWLYPEDQISDAPLKFFMAEITREKLFLSLHHELPYSLSVVTEALEEKEDGSLVVKQVIYVTKDS
HRTIILGKKGEMIKKISMESRSDLAKILDLKIHLFLFVKVREFWQNHLDECVGYVE

Sequences:

>Translated_296_residues
MDHISKKCSMNAIVGTTNAGKSTLINMLVGQKVAAVTPKVQTTRVRMHAVLNNENVQLIFIDTPGIFSPKTKLEKFIVKH
AWMSLKGIENVILLLDVKNYLNKHIEKIISRIKQSNINAILVVNKIDTVPTSSVDKAIEHMYSLHSFSKTFTISALHDIG
LSRLVDYLCEISPNGPWLYPEDQISDAPLKFFMAEITREKLFLSLHHELPYSLSVVTEALEEKEDGSLVVKQVIYVTKDS
HRTIILGKKGEMIKKISMESRSDLAKILDLKIHLFLFVKVREFWQNHLDECVGYVE
>Mature_296_residues
MDHISKKCSMNAIVGTTNAGKSTLINMLVGQKVAAVTPKVQTTRVRMHAVLNNENVQLIFIDTPGIFSPKTKLEKFIVKH
AWMSLKGIENVILLLDVKNYLNKHIEKIISRIKQSNINAILVVNKIDTVPTSSVDKAIEHMYSLHSFSKTFTISALHDIG
LSRLVDYLCEISPNGPWLYPEDQISDAPLKFFMAEITREKLFLSLHHELPYSLSVVTEALEEKEDGSLVVKQVIYVTKDS
HRTIILGKKGEMIKKISMESRSDLAKILDLKIHLFLFVKVREFWQNHLDECVGYVE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=29.6875, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=31.864406779661, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI87082120, Length=178, Percent_Identity=26.9662921348315, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33613; Mature: 33613

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHISKKCSMNAIVGTTNAGKSTLINMLVGQKVAAVTPKVQTTRVRMHAVLNNENVQLIF
CCCCHHHCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCHHHHEEEEEEECCCCEEEEE
IDTPGIFSPKTKLEKFIVKHAWMSLKGIENVILLLDVKNYLNKHIEKIISRIKQSNINAI
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEE
LVVNKIDTVPTSSVDKAIEHMYSLHSFSKTFTISALHDIGLSRLVDYLCEISPNGPWLYP
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHCCCCCCCCCC
EDQISDAPLKFFMAEITREKLFLSLHHELPYSLSVVTEALEEKEDGSLVVKQVIYVTKDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHEECCC
HRTIILGKKGEMIKKISMESRSDLAKILDLKIHLFLFVKVREFWQNHLDECVGYVE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDHISKKCSMNAIVGTTNAGKSTLINMLVGQKVAAVTPKVQTTRVRMHAVLNNENVQLIF
CCCCHHHCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCHHHHEEEEEEECCCCEEEEE
IDTPGIFSPKTKLEKFIVKHAWMSLKGIENVILLLDVKNYLNKHIEKIISRIKQSNINAI
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEE
LVVNKIDTVPTSSVDKAIEHMYSLHSFSKTFTISALHDIGLSRLVDYLCEISPNGPWLYP
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHCCCCCCCCCC
EDQISDAPLKFFMAEITREKLFLSLHHELPYSLSVVTEALEEKEDGSLVVKQVIYVTKDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHEECCC
HRTIILGKKGEMIKKISMESRSDLAKILDLKIHLFLFVKVREFWQNHLDECVGYVE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA