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The map label for this gene is xerD [H]

Identifier: 88658163

GI number: 88658163

Start: 162619

End: 163548

Strand: Direct

Name: xerD [H]

Synonym: ECH_0173

Alternate gene names: 88658163

Gene position: 162619-163548 (Clockwise)

Preceding gene: 88658035

Following gene: 88658354

Centisome position: 13.83

GC content: 30.75

Gene sequence:

>930_bases
ATGGATAATCAAAGATATGTAAATATTTTTCTTGAAGCGATAGTAGCAGAAAAACATGTATCTCATAATACTTATCAGAG
TTACAGGACTGATTTACTGGGACTCTGCAAATTTATTGATAGAAATGACCTTTTGTTGACAGATGCTAGTATACACGAAC
TGCAAGATTATATTAGGTTTTTGTATGAGAAGGGATATAAAGCAAATACTGTATCGAGGAAAATATCAGCTATTAAAAAT
TTATATGGGTTTTTATATAGAGACAATATCATTGAGAATGATCCTACTGTGTATTTGGATTCTCCTAAATTGTCCCGTTC
TCTTCCGAAAACGTTAAGTTATGAAGAAGTAAATATATTACTTGATGTTGCTGCTTTAGATGTTTCACCTGATGGAAGAA
GGATTAATGCTATTGTTAATATATTATATTCTTCAGGTATACGGATTTCTGAGTTAGTGTATTTGAAATTCCGTGAAGTG
AGAGAAGCTTTAGATGATGGTGATACAGAAATATGTCACATGAAAATTCAAGGGAAAGCAAAAAAAGAGAGGATAATATT
GTTAAATTCATCTGCTGTAACAAGTATACAAAAATATATGGAAGTTTATGAATATTTTATTCCAAATGGATATAAGATGT
CACAGTGGTTGTTTCCTGGTACAAAGTTTGATAATCCTGTAACAAGACAAAGGGTAGGTCAATTACTAAAGAATTTAGCT
ATGAATGCTGGTATCAATGTTACTCATGTTTCTCCTCATAAACTTCGACATTCTTTTGCGACACATTTGTTGAATAATGG
ATCAGATATTGTTTTTATTCAAAAGATGTTAGGACATGCTAATCTAGCAACTACACAAATATACACTCATGTTGCGAGTG
AAAGATTAAAGAGTATACTACTAAAATTTCATCCTTTACGTAATAAATAA

Upstream 100 bases:

>100_bases
TGTAGAGAATTAATAATCATGAAGAGATTGTTGCATTATTTGTAATAGCAATAGATTTGTTATGTGTTAGAATTCGAGGA
TATGCAAATGATTAGTTAGT

Downstream 100 bases:

>100_bases
GGGTGTATGCATATTTTAATGATATAAGCAAATTATTTGTATTGCTATAAGAGTTGTTGGTTTAGTTAAAGTTGGCGAAT
TTGGAATGGTATAGAAAGTT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MDNQRYVNIFLEAIVAEKHVSHNTYQSYRTDLLGLCKFIDRNDLLLTDASIHELQDYIRFLYEKGYKANTVSRKISAIKN
LYGFLYRDNIIENDPTVYLDSPKLSRSLPKTLSYEEVNILLDVAALDVSPDGRRINAIVNILYSSGIRISELVYLKFREV
REALDDGDTEICHMKIQGKAKKERIILLNSSAVTSIQKYMEVYEYFIPNGYKMSQWLFPGTKFDNPVTRQRVGQLLKNLA
MNAGINVTHVSPHKLRHSFATHLLNNGSDIVFIQKMLGHANLATTQIYTHVASERLKSILLKFHPLRNK

Sequences:

>Translated_309_residues
MDNQRYVNIFLEAIVAEKHVSHNTYQSYRTDLLGLCKFIDRNDLLLTDASIHELQDYIRFLYEKGYKANTVSRKISAIKN
LYGFLYRDNIIENDPTVYLDSPKLSRSLPKTLSYEEVNILLDVAALDVSPDGRRINAIVNILYSSGIRISELVYLKFREV
REALDDGDTEICHMKIQGKAKKERIILLNSSAVTSIQKYMEVYEYFIPNGYKMSQWLFPGTKFDNPVTRQRVGQLLKNLA
MNAGINVTHVSPHKLRHSFATHLLNNGSDIVFIQKMLGHANLATTQIYTHVASERLKSILLKFHPLRNK
>Mature_309_residues
MDNQRYVNIFLEAIVAEKHVSHNTYQSYRTDLLGLCKFIDRNDLLLTDASIHELQDYIRFLYEKGYKANTVSRKISAIKN
LYGFLYRDNIIENDPTVYLDSPKLSRSLPKTLSYEEVNILLDVAALDVSPDGRRINAIVNILYSSGIRISELVYLKFREV
REALDDGDTEICHMKIQGKAKKERIILLNSSAVTSIQKYMEVYEYFIPNGYKMSQWLFPGTKFDNPVTRQRVGQLLKNLA
MNAGINVTHVSPHKLRHSFATHLLNNGSDIVFIQKMLGHANLATTQIYTHVASERLKSILLKFHPLRNK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=38.7959866220736, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=29.6666666666667, Blast_Score=144, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35571; Mature: 35571

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQRYVNIFLEAIVAEKHVSHNTYQSYRTDLLGLCKFIDRNDLLLTDASIHELQDYIRF
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
LYEKGYKANTVSRKISAIKNLYGFLYRDNIIENDPTVYLDSPKLSRSLPKTLSYEEVNIL
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCCCCHHHHHEE
LDVAALDVSPDGRRINAIVNILYSSGIRISELVYLKFREVREALDDGDTEICHMKIQGKA
EEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
KKERIILLNSSAVTSIQKYMEVYEYFIPNGYKMSQWLFPGTKFDNPVTRQRVGQLLKNLA
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCHHHHHHHHHHHHHH
MNAGINVTHVSPHKLRHSFATHLLNNGSDIVFIQKMLGHANLATTQIYTHVASERLKSIL
HHCCCEEEECCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LKFHPLRNK
HHHCCCCCC
>Mature Secondary Structure
MDNQRYVNIFLEAIVAEKHVSHNTYQSYRTDLLGLCKFIDRNDLLLTDASIHELQDYIRF
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
LYEKGYKANTVSRKISAIKNLYGFLYRDNIIENDPTVYLDSPKLSRSLPKTLSYEEVNIL
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCCCCHHHHHEE
LDVAALDVSPDGRRINAIVNILYSSGIRISELVYLKFREVREALDDGDTEICHMKIQGKA
EEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
KKERIILLNSSAVTSIQKYMEVYEYFIPNGYKMSQWLFPGTKFDNPVTRQRVGQLLKNLA
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCHHHHHHHHHHHHHH
MNAGINVTHVSPHKLRHSFATHLLNNGSDIVFIQKMLGHANLATTQIYTHVASERLKSIL
HHCCCEEEECCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LKFHPLRNK
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]