Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 88657928

GI number: 88657928

Start: 816174

End: 816782

Strand: Reverse

Name: coaE

Synonym: ECH_0801

Alternate gene names: 88657928

Gene position: 816782-816174 (Counterclockwise)

Preceding gene: 88657971

Following gene: 88658451

Centisome position: 69.44

GC content: 28.41

Gene sequence:

>609_bases
ATGGTGATTTTTGGATTAACTGGTGGTATAGGTTCTGGTAAAAGTTTAGTTGCTAGCTATTTTAAAACATTGTTTAAGGC
AGTAGTATTTGATGCTGATCAAGTTGTATGTCAGTTATATAATTGTGACAACAGTGTTATAAAGCTTGTTAAGACATATT
TTCCAGATTCTGTGGATCACGGGGTTGTTAATAAGAATAGTTTAAGACAGCATTTTTTTGCTTATAGTAATTTATGGGTT
GAATTTCAGTCAACATTACATTCGATAATTTTAGAAAAACAGAAAAATTTTATTATGTTTCATAATAGACAATCAACTAA
GTATGTAGTACTTGATGTGCCTCTATTGATAGAATCTAATTTTTATAGTTGTTGTAATTTTATTATCCATGTTACAACTA
ATAGATTATTGCAGATGCAAAGGGTATTATATCGTGGTTTATCTATAAGAGAGTTTGAGTCGATTATAGCTATACAGCTG
TCTGAAAATGACAGAAAAAAATTTGCAAATTTTACTATTAGAACTGGGTTAAGTAAAGGTGATGTGTTATTTCAAATTCA
AAAGATAATGTTTGATATTAGTCATAGAAGTAAATATCTAAGTTGCTGA

Upstream 100 bases:

>100_bases
CTATGATTAAAATTATAAAGTGATCTTTTTGGTTAACAAGTTTTTTTATTATAGAAATGAGAATAGATTGTGTTTGTATT
GGTAGGGGTTATTTATAACT

Downstream 100 bases:

>100_bases
TGATGTTCAATTAGTGCATGTTTTTTGCATGAACAAAATATAAAATACATAAAAGATGCCTAATCAAAATTTTTAAATAT
GGGTCAAATTATAGGACACA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MVIFGLTGGIGSGKSLVASYFKTLFKAVVFDADQVVCQLYNCDNSVIKLVKTYFPDSVDHGVVNKNSLRQHFFAYSNLWV
EFQSTLHSIILEKQKNFIMFHNRQSTKYVVLDVPLLIESNFYSCCNFIIHVTTNRLLQMQRVLYRGLSIREFESIIAIQL
SENDRKKFANFTIRTGLSKGDVLFQIQKIMFDISHRSKYLSC

Sequences:

>Translated_202_residues
MVIFGLTGGIGSGKSLVASYFKTLFKAVVFDADQVVCQLYNCDNSVIKLVKTYFPDSVDHGVVNKNSLRQHFFAYSNLWV
EFQSTLHSIILEKQKNFIMFHNRQSTKYVVLDVPLLIESNFYSCCNFIIHVTTNRLLQMQRVLYRGLSIREFESIIAIQL
SENDRKKFANFTIRTGLSKGDVLFQIQKIMFDISHRSKYLSC
>Mature_202_residues
MVIFGLTGGIGSGKSLVASYFKTLFKAVVFDADQVVCQLYNCDNSVIKLVKTYFPDSVDHGVVNKNSLRQHFFAYSNLWV
EFQSTLHSIILEKQKNFIMFHNRQSTKYVVLDVPLLIESNFYSCCNFIIHVTTNRLLQMQRVLYRGLSIREFESIIAIQL
SENDRKKFANFTIRTGLSKGDVLFQIQKIMFDISHRSKYLSC

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Escherichia coli, GI1786292, Length=174, Percent_Identity=29.8850574712644, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=25.5, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_EHRCR (Q2GG34)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507599.1
- ProteinModelPortal:   Q2GG34
- SMR:   Q2GG34
- STRING:   Q2GG34
- GeneID:   3927164
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0801
- TIGR:   ECH_0801
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   HEFELIS
- ProtClustDB:   CLSK749105
- BioCyc:   ECHA205920:ECH_0801-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 23334; Mature: 23334

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIFGLTGGIGSGKSLVASYFKTLFKAVVFDADQVVCQLYNCDNSVIKLVKTYFPDSVDH
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
GVVNKNSLRQHFFAYSNLWVEFQSTLHSIILEKQKNFIMFHNRQSTKYVVLDVPLLIESN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECEEECCC
FYSCCNFIIHVTTNRLLQMQRVLYRGLSIREFESIIAIQLSENDRKKFANFTIRTGLSKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCHHHHHCCCEECCCCCC
DVLFQIQKIMFDISHRSKYLSC
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVIFGLTGGIGSGKSLVASYFKTLFKAVVFDADQVVCQLYNCDNSVIKLVKTYFPDSVDH
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
GVVNKNSLRQHFFAYSNLWVEFQSTLHSIILEKQKNFIMFHNRQSTKYVVLDVPLLIESN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECEEECCC
FYSCCNFIIHVTTNRLLQMQRVLYRGLSIREFESIIAIQLSENDRKKFANFTIRTGLSKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCHHHHHCCCEECCCCCC
DVLFQIQKIMFDISHRSKYLSC
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA