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The map label for this gene is putA [H]

Identifier: 88657803

GI number: 88657803

Start: 678638

End: 681772

Strand: Reverse

Name: putA [H]

Synonym: ECH_0667

Alternate gene names: 88657803

Gene position: 681772-678638 (Counterclockwise)

Preceding gene: 88657890

Following gene: 88658309

Centisome position: 57.96

GC content: 33.33

Gene sequence:

>3135_bases
ATGATAAGTGCATTACAAACGCCGAATGAAATACGTAGACGTATGCAAATGTTGTATCGTATAGAAGAAAATAGTTGTAC
AAGATATTTGACAGAAAAAACAGAAATATCACAAGATTCTAAAATTAGGATTTACAGTGTTGCAAAACAAATAATCGAAA
GAATAAGAGTAGATAGAAATTTAGGTATAATAGATGCTTTTATGCAAGAGTATGGTTTGTCAAATGAAGAAGGCATAGCT
CTTATGTGTTTAGCAGAATCTTTGTTAAGAATACCAGATGATTGTACAATAAATGATTTAATAAAAGATAAAATAGGGAA
CAGTATGTGGAGTAATCACATAGGAAGTTCTTCATCGATGTTTGTAAATGCAGCAACTTGGGGTTTGTTTATAGGTGGAA
AGGTATTAAAGGATAGTAATGATAGTACTAGATGGTTTGGTACCATAAATAATTTATTGAAAACAATGGGTGAGCCTATC
ATTAGAAAGGCAGTGCAACAAGCAATGTGTATTTTAGGAAAGCATTTTATAAAAGGAAGAGATATCACAGAAGCACTTAA
CAATAGAAGAGAAGGGGAACTGTATTCATTTGACATATTAGGGGAAGCTGCAAAAACAAGAAAAGATGCAGAAAGGTATT
TTACTGAATATATGGCAGCAGTGGATAGCATAGGAAAGTCTAAAGTTAATAATGAGATAGGAAATTTGATAGATTATGAT
GAGATATCAGTAAAAATATCTGCATTGCATAGTAGATATGAGTTTTCACAGATAGATAAAGTATTAGATGAGATAGTAGA
CAAATTACTTCAAATATGTAAATTGGCAAAAGAACATAATATTCGTGTGTGTGTTGATGCAGAAGAAGCAAGTAGGCTAG
AAATATCGTTAATGATACTTGAGAAGTTACGGTTTGACAGCAGTTTGAATGGATGGGAAGGTTTAGGATTGGCTGTACAG
GCATATCAGAAGAGAGCATTTTCAGTATTGGATTTTGTGGAAGATATATCAGTAAGATCCCATCATAAAATGATGGTAAG
GCTTGTAAAAGGTGCATATTGGGATTATGAAATAAAGAATGCTCAAGAATTGGGGTTAAGCAGCTATCCAGTGTTTACAA
GAAAAGTATATACTGATGTTTCATATTTAGCGTGTGCAAACAAAATTTTAAGTAAGCCAAATACTTTTTCTCCATGTTTT
GCTACACATAATGCTTACACATTAGCTGCGATATTAGAGATGGCAAATAAGGATCATCCAGGATTTGAATTTCAAAGATT
GCATGGCATGGGGGCTAATTTGTATGAGTATGTAACACAAGAATTAGCAGCAAATGTTAAATGTAGGGTTTATGCTCCTG
TTGGAAGTTATCAAGATTTACTTCCGTACTTAATTAGGAGGTTATTGGAAAATGGGGCAAATAGTTCGTTTATTAATCAG
TTAAATGATAGTAATGTATCATTGGAACAGTTGATAGAGGATCCATTAGAAAAAGCAAGAGAATTAGAATATTTACCTCA
TCCTAGTATACCATTGCCGAAGGATATATTTGGTCCTGAGAGGCTTAATTCTATGGGTATTGATATTACTGATTCTGTTA
CTTTAACAAATTTTAATGAAGAAATGAAAAATTATCAAACTTGTAAATTCAAAGCAGCTCCAATTATAGGTGGAAAAGAA
TTAGATGGTAATTTTATAGAGGTATTTTCTCCAACAAATTCTGAGGATATTATTGGGGAAGTATTATTTACGGATACTGC
ACAAGCATTATCAGCTTTAGATATGGCTTATAATGCATTTAAAGATTGGTCTAATATTCCAGTTTCCACTCGTGCTGCTA
TATTAGAAAAAGCAGCTAATTTAATAGAAGAGAATAAGGCAAAATTAATAATGTTACTCATTAGAGAGGGAGGTAAGGTT
ATTTCTGATGCTATTGCAGAGATAAGGGAAGCTGTTGACTTTTTACGTTATTATGCAGTTCTTGGAAGACAAGAGTTAGA
ACAATCAAGAAAGTTGCCTGGTCCTGTAGGGGAAGATAATTACCTTTACTTTAGGAGCAGAGGTGTATTTGTGTGTATAT
CTCCTTGGAATTTCCCATTAGCGATATTTGTTGGTCCTATTGCTGCAGCATTGGTTACTGGAAATACTGTACTTGCAAAA
CCTGCTGAACAAACTTCTATTATTGCTTATGAAACAGTGAAACTATTGCATGATGCTGGAGTACCAAAAGAAGTTCTACA
CTTGTTATTAGGTAGTGGTAAAGAATTAGGGGAAGCATTGTTAAGGAATGAAAAAATAGGTGGTGTAGCATTTACTGGTT
CAACAGAGACAGCTAGAATAATTAATCAATCTATTGCAGAAAAAGAAGGTGGTATTATTCCATTCATAGCTGAAACTGGT
GGTTTAAATACTATGATAACTGATACTTCTGCGTTGATAGAACAAGTTACGAATGATGTAATAACATCAGCGTTTAAGAG
TGCTGGACAAAGATGTTCTGCATTAAGAGTGTTGTTTGTACAAGAGGAAGTAGCAGATAAACAAATTGAAATGATTTGTG
GGGCTATGGAAGATTTAGTTGTAGGTGATCCTATGTTGTTAAAAACAGATATAGGTCCAGTGATAGATAAAGCGTCACAA
GAAATGTTGATAGCTCATGAAGATAGGATGTCACGAGAAGCAAAATTGTTATATAAAGTTAAGTTAGGGGAAGATTGCGA
AAAAGGTTATTTTTTTGCTCCATGTGTATATGAAATACAAAGTATATCTCAGTTAAAGAGGGAAGTATTTGGTCCAATAT
TACATATAATCCGCTATAAAAAAGGAGACTTGCACAGAATTTTAGATGAAATTAATAGTACAGGATATGGTTTAACATTT
GCTGTACAGAGTAGAGTACAAAGTAATATTGATGTTATTATTGATAGTGTCAATGTTGGAAATGTTTATGTAAATAGGAA
TCAAGTCGGAGCAGTAGTAGGAGTACAACCTTTTGGAGGGCAAGGGTTATCAGGTACTGGCCCTAAAGCAGGTGGACCAT
ACTATTTACATAGATTCCTAACAGAAAAGGTAGTGAGTATTAATACTACAGCTTTAGGTGGAAATACTACATTAATGTGT
TTAACTGATCAGTAA

Upstream 100 bases:

>100_bases
GTGTTTAATTATTAACTTCATAATGAATTTGATTAAATGTTCTAATGTTAACTAATATGCTGATGTTGCAAATATTAGGT
ATTAATGGGAGATATGAGAA

Downstream 100 bases:

>100_bases
AAATTTTGTAAGTGAGACATTCACAAATGTTCTATTTATGTTTTCATAAATACTTGTATAGGTCATAATCAAGGTTGAAG
TAATAATAGGCCTACGCTTT

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1044; Mature: 1044

Protein sequence:

>1044_residues
MISALQTPNEIRRRMQMLYRIEENSCTRYLTEKTEISQDSKIRIYSVAKQIIERIRVDRNLGIIDAFMQEYGLSNEEGIA
LMCLAESLLRIPDDCTINDLIKDKIGNSMWSNHIGSSSSMFVNAATWGLFIGGKVLKDSNDSTRWFGTINNLLKTMGEPI
IRKAVQQAMCILGKHFIKGRDITEALNNRREGELYSFDILGEAAKTRKDAERYFTEYMAAVDSIGKSKVNNEIGNLIDYD
EISVKISALHSRYEFSQIDKVLDEIVDKLLQICKLAKEHNIRVCVDAEEASRLEISLMILEKLRFDSSLNGWEGLGLAVQ
AYQKRAFSVLDFVEDISVRSHHKMMVRLVKGAYWDYEIKNAQELGLSSYPVFTRKVYTDVSYLACANKILSKPNTFSPCF
ATHNAYTLAAILEMANKDHPGFEFQRLHGMGANLYEYVTQELAANVKCRVYAPVGSYQDLLPYLIRRLLENGANSSFINQ
LNDSNVSLEQLIEDPLEKARELEYLPHPSIPLPKDIFGPERLNSMGIDITDSVTLTNFNEEMKNYQTCKFKAAPIIGGKE
LDGNFIEVFSPTNSEDIIGEVLFTDTAQALSALDMAYNAFKDWSNIPVSTRAAILEKAANLIEENKAKLIMLLIREGGKV
ISDAIAEIREAVDFLRYYAVLGRQELEQSRKLPGPVGEDNYLYFRSRGVFVCISPWNFPLAIFVGPIAAALVTGNTVLAK
PAEQTSIIAYETVKLLHDAGVPKEVLHLLLGSGKELGEALLRNEKIGGVAFTGSTETARIINQSIAEKEGGIIPFIAETG
GLNTMITDTSALIEQVTNDVITSAFKSAGQRCSALRVLFVQEEVADKQIEMICGAMEDLVVGDPMLLKTDIGPVIDKASQ
EMLIAHEDRMSREAKLLYKVKLGEDCEKGYFFAPCVYEIQSISQLKREVFGPILHIIRYKKGDLHRILDEINSTGYGLTF
AVQSRVQSNIDVIIDSVNVGNVYVNRNQVGAVVGVQPFGGQGLSGTGPKAGGPYYLHRFLTEKVVSINTTALGGNTTLMC
LTDQ

Sequences:

>Translated_1044_residues
MISALQTPNEIRRRMQMLYRIEENSCTRYLTEKTEISQDSKIRIYSVAKQIIERIRVDRNLGIIDAFMQEYGLSNEEGIA
LMCLAESLLRIPDDCTINDLIKDKIGNSMWSNHIGSSSSMFVNAATWGLFIGGKVLKDSNDSTRWFGTINNLLKTMGEPI
IRKAVQQAMCILGKHFIKGRDITEALNNRREGELYSFDILGEAAKTRKDAERYFTEYMAAVDSIGKSKVNNEIGNLIDYD
EISVKISALHSRYEFSQIDKVLDEIVDKLLQICKLAKEHNIRVCVDAEEASRLEISLMILEKLRFDSSLNGWEGLGLAVQ
AYQKRAFSVLDFVEDISVRSHHKMMVRLVKGAYWDYEIKNAQELGLSSYPVFTRKVYTDVSYLACANKILSKPNTFSPCF
ATHNAYTLAAILEMANKDHPGFEFQRLHGMGANLYEYVTQELAANVKCRVYAPVGSYQDLLPYLIRRLLENGANSSFINQ
LNDSNVSLEQLIEDPLEKARELEYLPHPSIPLPKDIFGPERLNSMGIDITDSVTLTNFNEEMKNYQTCKFKAAPIIGGKE
LDGNFIEVFSPTNSEDIIGEVLFTDTAQALSALDMAYNAFKDWSNIPVSTRAAILEKAANLIEENKAKLIMLLIREGGKV
ISDAIAEIREAVDFLRYYAVLGRQELEQSRKLPGPVGEDNYLYFRSRGVFVCISPWNFPLAIFVGPIAAALVTGNTVLAK
PAEQTSIIAYETVKLLHDAGVPKEVLHLLLGSGKELGEALLRNEKIGGVAFTGSTETARIINQSIAEKEGGIIPFIAETG
GLNTMITDTSALIEQVTNDVITSAFKSAGQRCSALRVLFVQEEVADKQIEMICGAMEDLVVGDPMLLKTDIGPVIDKASQ
EMLIAHEDRMSREAKLLYKVKLGEDCEKGYFFAPCVYEIQSISQLKREVFGPILHIIRYKKGDLHRILDEINSTGYGLTF
AVQSRVQSNIDVIIDSVNVGNVYVNRNQVGAVVGVQPFGGQGLSGTGPKAGGPYYLHRFLTEKVVSINTTALGGNTTLMC
LTDQ
>Mature_1044_residues
MISALQTPNEIRRRMQMLYRIEENSCTRYLTEKTEISQDSKIRIYSVAKQIIERIRVDRNLGIIDAFMQEYGLSNEEGIA
LMCLAESLLRIPDDCTINDLIKDKIGNSMWSNHIGSSSSMFVNAATWGLFIGGKVLKDSNDSTRWFGTINNLLKTMGEPI
IRKAVQQAMCILGKHFIKGRDITEALNNRREGELYSFDILGEAAKTRKDAERYFTEYMAAVDSIGKSKVNNEIGNLIDYD
EISVKISALHSRYEFSQIDKVLDEIVDKLLQICKLAKEHNIRVCVDAEEASRLEISLMILEKLRFDSSLNGWEGLGLAVQ
AYQKRAFSVLDFVEDISVRSHHKMMVRLVKGAYWDYEIKNAQELGLSSYPVFTRKVYTDVSYLACANKILSKPNTFSPCF
ATHNAYTLAAILEMANKDHPGFEFQRLHGMGANLYEYVTQELAANVKCRVYAPVGSYQDLLPYLIRRLLENGANSSFINQ
LNDSNVSLEQLIEDPLEKARELEYLPHPSIPLPKDIFGPERLNSMGIDITDSVTLTNFNEEMKNYQTCKFKAAPIIGGKE
LDGNFIEVFSPTNSEDIIGEVLFTDTAQALSALDMAYNAFKDWSNIPVSTRAAILEKAANLIEENKAKLIMLLIREGGKV
ISDAIAEIREAVDFLRYYAVLGRQELEQSRKLPGPVGEDNYLYFRSRGVFVCISPWNFPLAIFVGPIAAALVTGNTVLAK
PAEQTSIIAYETVKLLHDAGVPKEVLHLLLGSGKELGEALLRNEKIGGVAFTGSTETARIINQSIAEKEGGIIPFIAETG
GLNTMITDTSALIEQVTNDVITSAFKSAGQRCSALRVLFVQEEVADKQIEMICGAMEDLVVGDPMLLKTDIGPVIDKASQ
EMLIAHEDRMSREAKLLYKVKLGEDCEKGYFFAPCVYEIQSISQLKREVFGPILHIIRYKKGDLHRILDEINSTGYGLTF
AVQSRVQSNIDVIIDSVNVGNVYVNRNQVGAVVGVQPFGGQGLSGTGPKAGGPYYLHRFLTEKVVSINTTALGGNTTLMC
LTDQ

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=30.0207039337474, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=30.0207039337474, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=30.0207039337474, Blast_Score=196, Evalue=9e-50,
Organism=Homo sapiens, GI25777732, Length=451, Percent_Identity=31.2638580931264, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI21361176, Length=477, Percent_Identity=29.559748427673, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI153266822, Length=450, Percent_Identity=30.4444444444444, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI25777724, Length=474, Percent_Identity=29.535864978903, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI25777730, Length=452, Percent_Identity=30.9734513274336, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777728, Length=426, Percent_Identity=30.2816901408451, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI238814322, Length=477, Percent_Identity=29.559748427673, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI12007648, Length=478, Percent_Identity=27.6150627615063, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI21614513, Length=504, Percent_Identity=28.3730158730159, Blast_Score=160, Evalue=8e-39,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=28.7305122494432, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI4507229, Length=442, Percent_Identity=28.9592760180996, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI188035924, Length=481, Percent_Identity=25.5717255717256, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777726, Length=474, Percent_Identity=27.4261603375527, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI310128093, Length=464, Percent_Identity=26.0775862068966, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI310128103, Length=464, Percent_Identity=26.0775862068966, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI25777721, Length=455, Percent_Identity=27.9120879120879, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI25952152, Length=472, Percent_Identity=25.4237288135593, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI11095441, Length=441, Percent_Identity=26.530612244898, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI310128091, Length=464, Percent_Identity=24.5689655172414, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI310128087, Length=288, Percent_Identity=28.125, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI71773324, Length=412, Percent_Identity=23.0582524271845, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI4502043, Length=420, Percent_Identity=23.3333333333333, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI238814371, Length=420, Percent_Identity=23.3333333333333, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128099, Length=238, Percent_Identity=27.7310924369748, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128101, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128089, Length=323, Percent_Identity=25.3869969040248, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI301500698, Length=477, Percent_Identity=22.6415094339623, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI4557303, Length=342, Percent_Identity=24.2690058479532, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=342, Percent_Identity=24.2690058479532, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=25.1612903225806, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI206597441, Length=431, Percent_Identity=22.969837587007, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI206597439, Length=431, Percent_Identity=22.969837587007, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI22907049, Length=431, Percent_Identity=22.969837587007, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=23.9520958083832, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=23.9520958083832, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI310128097, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787250, Length=1033, Percent_Identity=46.6602129719264, Blast_Score=931, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=493, Percent_Identity=29.4117647058824, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1787684, Length=477, Percent_Identity=29.1404612159329, Blast_Score=178, Evalue=2e-45,
Organism=Escherichia coli, GI1788042, Length=479, Percent_Identity=29.6450939457203, Blast_Score=166, Evalue=7e-42,
Organism=Escherichia coli, GI87081896, Length=471, Percent_Identity=28.2377919320594, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1787715, Length=458, Percent_Identity=29.2576419213974, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1787558, Length=450, Percent_Identity=28.2222222222222, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI87082295, Length=473, Percent_Identity=27.6955602536998, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1786504, Length=461, Percent_Identity=26.4642082429501, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081926, Length=439, Percent_Identity=23.9179954441913, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1787653, Length=401, Percent_Identity=25.1870324189526, Blast_Score=83, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534447, Length=477, Percent_Identity=30.188679245283, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25144435, Length=475, Percent_Identity=29.2631578947368, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=476, Percent_Identity=29.4117647058824, Blast_Score=172, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=413, Percent_Identity=30.7506053268765, Blast_Score=169, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17551164, Length=451, Percent_Identity=30.5986696230599, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI32564736, Length=426, Percent_Identity=29.81220657277, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI133930964, Length=515, Percent_Identity=28.3495145631068, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17534119, Length=491, Percent_Identity=26.6802443991853, Blast_Score=153, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25143874, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=442, Percent_Identity=26.9230769230769, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115534176, Length=498, Percent_Identity=27.1084337349398, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=405, Percent_Identity=27.6543209876543, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71995606, Length=426, Percent_Identity=26.2910798122066, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=382, Percent_Identity=26.1780104712042, Blast_Score=125, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71986308, Length=467, Percent_Identity=26.338329764454, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=298, Percent_Identity=27.8523489932886, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=446, Percent_Identity=25.3363228699552, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=446, Percent_Identity=25.3363228699552, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=446, Percent_Identity=25.3363228699552, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=350, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=32.0088300220751, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6321826, Length=507, Percent_Identity=30.1775147928994, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319478, Length=495, Percent_Identity=27.6767676767677, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=478, Percent_Identity=28.0334728033473, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=464, Percent_Identity=29.3103448275862, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320917, Length=458, Percent_Identity=28.82096069869, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6325196, Length=477, Percent_Identity=27.6729559748428, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321828, Length=496, Percent_Identity=24.5967741935484, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=27.6073619631902, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129399, Length=477, Percent_Identity=29.559748427673, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281362580, Length=454, Percent_Identity=30.1762114537445, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472918, Length=454, Percent_Identity=30.1762114537445, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472926, Length=454, Percent_Identity=30.1762114537445, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472936, Length=454, Percent_Identity=30.1762114537445, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356737, Length=454, Percent_Identity=30.1762114537445, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24585660, Length=478, Percent_Identity=29.2887029288703, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24668425, Length=505, Percent_Identity=26.5346534653465, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24668417, Length=505, Percent_Identity=26.5346534653465, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24668413, Length=505, Percent_Identity=26.5346534653465, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571802, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571800, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571806, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571798, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571796, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571794, Length=452, Percent_Identity=28.0973451327434, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28574525, Length=492, Percent_Identity=25.609756097561, Blast_Score=146, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24650465, Length=456, Percent_Identity=26.7543859649123, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24666674, Length=454, Percent_Identity=25.9911894273128, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24638876, Length=452, Percent_Identity=28.7610619469027, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638878, Length=452, Percent_Identity=28.7610619469027, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281360299, Length=456, Percent_Identity=25.219298245614, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281360297, Length=456, Percent_Identity=25.219298245614, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281360295, Length=456, Percent_Identity=25.219298245614, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24586250, Length=456, Percent_Identity=25.219298245614, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281360301, Length=456, Percent_Identity=25.219298245614, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45552499, Length=455, Percent_Identity=25.0549450549451, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281360303, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281360293, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116299; Mature: 116299

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISALQTPNEIRRRMQMLYRIEENSCTRYLTEKTEISQDSKIRIYSVAKQIIERIRVDRN
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
LGIIDAFMQEYGLSNEEGIALMCLAESLLRIPDDCTINDLIKDKIGNSMWSNHIGSSSSM
CCHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCE
FVNAATWGLFIGGKVLKDSNDSTRWFGTINNLLKTMGEPIIRKAVQQAMCILGKHFIKGR
EEEEHHHHHEECCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
DITEALNNRREGELYSFDILGEAAKTRKDAERYFTEYMAAVDSIGKSKVNNEIGNLIDYD
CHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EISVKISALHSRYEFSQIDKVLDEIVDKLLQICKLAKEHNIRVCVDAEEASRLEISLMIL
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
EKLRFDSSLNGWEGLGLAVQAYQKRAFSVLDFVEDISVRSHHKMMVRLVKGAYWDYEIKN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
AQELGLSSYPVFTRKVYTDVSYLACANKILSKPNTFSPCFATHNAYTLAAILEMANKDHP
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMGANLYEYVTQELAANVKCRVYAPVGSYQDLLPYLIRRLLENGANSSFINQ
CCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHH
LNDSNVSLEQLIEDPLEKARELEYLPHPSIPLPKDIFGPERLNSMGIDITDSVTLTNFNE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCEEEECCHH
EMKNYQTCKFKAAPIIGGKELDGNFIEVFSPTNSEDIIGEVLFTDTAQALSALDMAYNAF
HHCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDWSNIPVSTRAAILEKAANLIEENKAKLIMLLIREGGKVISDAIAEIREAVDFLRYYAV
HCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LGRQELEQSRKLPGPVGEDNYLYFRSRGVFVCISPWNFPLAIFVGPIAAALVTGNTVLAK
HHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEC
PAEQTSIIAYETVKLLHDAGVPKEVLHLLLGSGKELGEALLRNEKIGGVAFTGSTETARI
CCCCCEEHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCHHHHH
INQSIAEKEGGIIPFIAETGGLNTMITDTSALIEQVTNDVITSAFKSAGQRCSALRVLFV
HHHHHHHHCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEVADKQIEMICGAMEDLVVGDPMLLKTDIGPVIDKASQEMLIAHEDRMSREAKLLYKV
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCHHHEEHHHHHHCCHHEEEEEE
KLGEDCEKGYFFAPCVYEIQSISQLKREVFGPILHIIRYKKGDLHRILDEINSTGYGLTF
ECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEH
AVQSRVQSNIDVIIDSVNVGNVYVNRNQVGAVVGVQPFGGQGLSGTGPKAGGPYYLHRFL
HHHHHHHCCCEEEEEEEEECEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
TEKVVSINTTALGGNTTLMCLTDQ
HHHHHEEEEEEECCCEEEEEEECC
>Mature Secondary Structure
MISALQTPNEIRRRMQMLYRIEENSCTRYLTEKTEISQDSKIRIYSVAKQIIERIRVDRN
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
LGIIDAFMQEYGLSNEEGIALMCLAESLLRIPDDCTINDLIKDKIGNSMWSNHIGSSSSM
CCHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCE
FVNAATWGLFIGGKVLKDSNDSTRWFGTINNLLKTMGEPIIRKAVQQAMCILGKHFIKGR
EEEEHHHHHEECCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
DITEALNNRREGELYSFDILGEAAKTRKDAERYFTEYMAAVDSIGKSKVNNEIGNLIDYD
CHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EISVKISALHSRYEFSQIDKVLDEIVDKLLQICKLAKEHNIRVCVDAEEASRLEISLMIL
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
EKLRFDSSLNGWEGLGLAVQAYQKRAFSVLDFVEDISVRSHHKMMVRLVKGAYWDYEIKN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
AQELGLSSYPVFTRKVYTDVSYLACANKILSKPNTFSPCFATHNAYTLAAILEMANKDHP
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMGANLYEYVTQELAANVKCRVYAPVGSYQDLLPYLIRRLLENGANSSFINQ
CCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHH
LNDSNVSLEQLIEDPLEKARELEYLPHPSIPLPKDIFGPERLNSMGIDITDSVTLTNFNE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCEECCEEEECCHH
EMKNYQTCKFKAAPIIGGKELDGNFIEVFSPTNSEDIIGEVLFTDTAQALSALDMAYNAF
HHCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDWSNIPVSTRAAILEKAANLIEENKAKLIMLLIREGGKVISDAIAEIREAVDFLRYYAV
HCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LGRQELEQSRKLPGPVGEDNYLYFRSRGVFVCISPWNFPLAIFVGPIAAALVTGNTVLAK
HHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEC
PAEQTSIIAYETVKLLHDAGVPKEVLHLLLGSGKELGEALLRNEKIGGVAFTGSTETARI
CCCCCEEHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCHHHHH
INQSIAEKEGGIIPFIAETGGLNTMITDTSALIEQVTNDVITSAFKSAGQRCSALRVLFV
HHHHHHHHCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEVADKQIEMICGAMEDLVVGDPMLLKTDIGPVIDKASQEMLIAHEDRMSREAKLLYKV
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCHHHEEHHHHHHCCHHEEEEEE
KLGEDCEKGYFFAPCVYEIQSISQLKREVFGPILHIIRYKKGDLHRILDEINSTGYGLTF
ECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEH
AVQSRVQSNIDVIIDSVNVGNVYVNRNQVGAVVGVQPFGGQGLSGTGPKAGGPYYLHRFL
HHHHHHHCCCEEEEEEEEECEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
TEKVVSINTTALGGNTTLMCLTDQ
HHHHHEEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]