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The map label for this gene is nrdR

Identifier: 88608794

GI number: 88608794

Start: 290182

End: 290631

Strand: Direct

Name: nrdR

Synonym: NSE_0352

Alternate gene names: 88608794

Gene position: 290182-290631 (Clockwise)

Preceding gene: 88608157

Following gene: 88608085

Centisome position: 33.78

GC content: 38.89

Gene sequence:

>450_bases
ATGAAATGTCCATTTTGTGGTAATCGAGATACTAATGTCAGAGATTCACGTTCTGTGAATGAAGGTACCTTCATAAAAAG
GAGGCGCTTCTGTGGTGAGTGTGGTGCTAAGTTTACTACTTTTGAGACTATACAGCTTAAAGAAATAAAGGTCATTAAGA
AGAACGGTAGTTGTGAAAGTTTCGACAGAGAAAAGGCGATGCGTTCAGTCGAAGTTGCGTTACGCAAAAGGCCTGTGACA
CGGGAAAGGGTAGATGAATTAATGAATAGTGTAATTTACAAGATTGAACGCATTCATGACGCAAAGATTACAGCAAAGGT
TATTGGGGAGCTGATTATGGAAGAGCTTGCTACTCTGGATAAAGTTGCTTTTATTCGGTTTGCCTCTGTATACATGAACT
TTGAAAATGAAAAGGATTTCGTTCAGTTGATAGGTAGTCTTACTTCCTAG

Upstream 100 bases:

>100_bases
CTTGCTTGGGTAAATCTGTATTCTATGCGATTGGTTCTTCAGAGCTGATCATTTTGAATAGTGGCCTAAGAGCCAAGTTT
ACACTTTCCGTTCGAGTGAT

Downstream 100 bases:

>100_bases
CAAGGTCCCTCTCAGTTCTTGCAAAGTGATTGTGATGGTTGCTTTTCCCCCTCTATCTGAGAATGAATATCCTCATTGTA
AAGAATTTTAGCAAGTATTT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKCPFCGNRDTNVRDSRSVNEGTFIKRRRFCGECGAKFTTFETIQLKEIKVIKKNGSCESFDREKAMRSVEVALRKRPVT
RERVDELMNSVIYKIERIHDAKITAKVIGELIMEELATLDKVAFIRFASVYMNFENEKDFVQLIGSLTS

Sequences:

>Translated_149_residues
MKCPFCGNRDTNVRDSRSVNEGTFIKRRRFCGECGAKFTTFETIQLKEIKVIKKNGSCESFDREKAMRSVEVALRKRPVT
RERVDELMNSVIYKIERIHDAKITAKVIGELIMEELATLDKVAFIRFASVYMNFENEKDFVQLIGSLTS
>Mature_149_residues
MKCPFCGNRDTNVRDSRSVNEGTFIKRRRFCGECGAKFTTFETIQLKEIKVIKKNGSCESFDREKAMRSVEVALRKRPVT
RERVDELMNSVIYKIERIHDAKITAKVIGELIMEELATLDKVAFIRFASVYMNFENEKDFVQLIGSLTS

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.2176870748299, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_NEOSM (Q2GE55)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506241.1
- STRING:   Q2GE55
- GeneID:   3931590
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0352
- TIGR:   NSE_0352
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q2GE55
- ProtClustDB:   PRK00464
- BioCyc:   NSEN222891:NSE_0352-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17212; Mature: 17212

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGNRDTNVRDSRSVNEGTFIKRRRFCGECGAKFTTFETIQLKEIKVIKKNGSCES
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHEEHHHHEEEECCCCCCH
FDREKAMRSVEVALRKRPVTRERVDELMNSVIYKIERIHDAKITAKVIGELIMEELATLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAFIRFASVYMNFENEKDFVQLIGSLTS
HHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCGNRDTNVRDSRSVNEGTFIKRRRFCGECGAKFTTFETIQLKEIKVIKKNGSCES
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHEEHHHHEEEECCCCCCH
FDREKAMRSVEVALRKRPVTRERVDELMNSVIYKIERIHDAKITAKVIGELIMEELATLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAFIRFASVYMNFENEKDFVQLIGSLTS
HHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA