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The map label for this gene is purQ [H]

Identifier: 88608768

GI number: 88608768

Start: 364994

End: 365716

Strand: Reverse

Name: purQ [H]

Synonym: NSE_0448

Alternate gene names: 88608768

Gene position: 365716-364994 (Counterclockwise)

Preceding gene: 88608509

Following gene: 88608279

Centisome position: 42.57

GC content: 43.43

Gene sequence:

>723_bases
ATGGCTAGTGTACTTGTACTATCTGGGTATGGACTCAATTGCGAGGATGAGACACTTCGGGCATTTGAGTTGTCCGGTTT
TGCTGGAAGCGTGCTGCACTTAGATGATTTGCTCAACAAGCCTAATAAGCTTTGTAATCACCAAGTTTTAGCGATCCCTG
GTGGTTTCTCTTTTGCCGATAATACGGGTGCAGGAAACGCGTTCGCGTGCAAAACTATCCCCTTACTAGAAGAAGTAGAG
AATTTCCTTAACAAAGACAAGCTGGTCATAGGTATATGTAACGGCGCTCAAATACTTACACGTTTGATCAAGGACTTGGA
AGTCACTTTTGAGGCAAATACATCGAACCAGTATCAATGTGGATGGCAAGACATTGAAGTGCCTGAAAGTGATTCTATTT
GGATGAGAGGTATTCATGAAATCCGTTTACCAATTGCGCATGGTGAAGGAAAATTACTGCCCTTAGATAAGACCAATCTG
AAAGTCAGTGTCGCCATGCGATATAAGCAGGATGTTAATGGCTCTTACAACAGAATTGCTGCTGTCACAGCATACGGCGG
AAAGATGTTGATCACCATGCCCCATCCGGAGAGGGCGGTTTCCCTAGTACAAACTGACGACTACTATTTAGTTCGAGAGG
AGTATAGAAGAAGGTACTTACCAACCCCTAAAGATGGCCCTGGGATGCGAATTTTTAAGAACGCATATGATTACTTTCAC
TAA

Upstream 100 bases:

>100_bases
AGGGAATGAACAGCGTAAAGACAACCTAACAGCATTAGATATTTCTATATGTATTTTGTACGTGAGTGTGTTACACTATG
CTCCGCTTTTTGAGAAGAAG

Downstream 100 bases:

>100_bases
TCCCTCTGTTTAACTGTATTACTTCGGTGTGTTTAAGTTATTTAGTACGTCTTACAGTCACGTCGCGATGATAAGTCATG
CGTTTCATCTTTATCATGAC

Product: putative phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFADNTGAGNAFACKTIPLLEEVE
NFLNKDKLVIGICNGAQILTRLIKDLEVTFEANTSNQYQCGWQDIEVPESDSIWMRGIHEIRLPIAHGEGKLLPLDKTNL
KVSVAMRYKQDVNGSYNRIAAVTAYGGKMLITMPHPERAVSLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH

Sequences:

>Translated_240_residues
MASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFADNTGAGNAFACKTIPLLEEVE
NFLNKDKLVIGICNGAQILTRLIKDLEVTFEANTSNQYQCGWQDIEVPESDSIWMRGIHEIRLPIAHGEGKLLPLDKTNL
KVSVAMRYKQDVNGSYNRIAAVTAYGGKMLITMPHPERAVSLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH
>Mature_239_residues
ASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFADNTGAGNAFACKTIPLLEEVEN
FLNKDKLVIGICNGAQILTRLIKDLEVTFEANTSNQYQCGWQDIEVPESDSIWMRGIHEIRLPIAHGEGKLLPLDKTNLK
VSVAMRYKQDVNGSYNRIAAVTAYGGKMLITMPHPERAVSLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=260, Percent_Identity=33.4615384615385, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17553022, Length=272, Percent_Identity=25.7352941176471, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=271, Percent_Identity=29.8892988929889, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582111, Length=267, Percent_Identity=28.8389513108614, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24582109, Length=267, Percent_Identity=28.8389513108614, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17137292, Length=267, Percent_Identity=28.8389513108614, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 26890; Mature: 26759

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFAD
CCEEEEEECCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCCHHHHCCEEEEECCCCCCCC
NTGAGNAFACKTIPLLEEVENFLNKDKLVIGICNGAQILTRLIKDLEVTFEANTSNQYQC
CCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEEECCCCCEEE
GWQDIEVPESDSIWMRGIHEIRLPIAHGEGKLLPLDKTNLKVSVAMRYKQDVNGSYNRIA
CCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEE
AVTAYGGKMLITMPHPERAVSLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH
EEEECCCEEEEECCCCHHHEEEEECCCEEEEEHHHHHHCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ASVLVLSGYGLNCEDETLRAFELSGFAGSVLHLDDLLNKPNKLCNHQVLAIPGGFSFAD
CEEEEEECCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCCHHHHCCEEEEECCCCCCCC
NTGAGNAFACKTIPLLEEVENFLNKDKLVIGICNGAQILTRLIKDLEVTFEANTSNQYQC
CCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEEECCCCCEEE
GWQDIEVPESDSIWMRGIHEIRLPIAHGEGKLLPLDKTNLKVSVAMRYKQDVNGSYNRIA
CCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEE
AVTAYGGKMLITMPHPERAVSLVQTDDYYLVREEYRRRYLPTPKDGPGMRIFKNAYDYFH
EEEECCCEEEEECCCCHHHEEEEECCCEEEEEHHHHHHCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA