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The map label for this gene is 88608757

Identifier: 88608757

GI number: 88608757

Start: 735399

End: 737027

Strand: Reverse

Name: 88608757

Synonym: NSE_0829

Alternate gene names: NA

Gene position: 737027-735399 (Counterclockwise)

Preceding gene: 88608531

Following gene: 88608744

Centisome position: 85.8

GC content: 42.42

Gene sequence:

>1629_bases
ATGACGGATAATAATTTAATATTTTTGCCTCTTGGGGGTACTGGTGAAATAGGAATGAATGTCACCTTGTATGGATACAA
GGGTCGGTGGATCATGATCGATTGTGGGGCAGGTTTTGCTGACGCGGAATTGCCTGGGATAGACATCGTTGTTGCAGATA
TCAGTTTCATCGAAGAGCGCAAGGATGACCTTTTAGCTATAATTATCACTCATATTCACGAAGACCACTGTGGGGCACTT
CCGTATTTGTGGGATAGATTGGCTGTTCCTGTATATACTACCCAGTTCACTGCGAATTTCCTGCTAAAAAAAATTGGCCG
TGATAAGGTGCAATTTCCGATTCATGTTGTGGAGCCGGGGAAGTTGTTGCATTTGGGAGATTTTACGCTTGAATTTATTA
ACATGACCCATTCGGTACCCGAAATGAATGCAATTGCAATTCATACTGCCGATAAAGTGGTGATTCATAGTGGGGATTGG
AAAATAGACGATGATCCCGTTGTTGGAAAGACATGTGATTTTAAAAGACTTGAAGAACTCTCGGAAAAGGGAGTTCTGGC
AATGGTGTGTGATTCAACTAATGTGTTTTCTCACGGGAGGTCCGATTCTGAATCCTCATTGAGGGAGCCACTGATGGAGG
TTATTTCCAGTGCCAGTGGAGCGTGTGTTGTGACGCTTTTTTCTTCGAACATTGCAAGAATAGAGACTGTGACAAGGATA
GCAAATGAATACGGAAAGACGGTTGTTGTTCTAGGGAGATCTCTTCTTTCTGTAATTTCTGCTGCAAAAGAGACTGGCTA
TTTAAAAGATCTCAACTACATAGATGAGATTGGATTGGCTCACTATAGTGGCAGTAGAAAGTCGCTGATTATTCTTGCAA
CGGGATGTCAAGGAGATGAGCTGGCTGCCGTTAATAGGCTTTCACAGGGTACGCATAATAGTTTCGCCATCAATGCTGAT
GACACTATCATCTTTTCCTCGAAAATGATTCCAGGAAACGAAAAGAGGATAGCAAAGATGATTAATAGGTTTATTGCTGT
GGGTGTGAATGTTGTGACTGAGAGAACGCATTCCGTGCATGTTTCGGGACATCCATACAGAGACGAGTTAAAGCAGCTAT
ATCAGTTGCTTAAACCAAAGATTCTTATTCCCGTGCATGGAGAAAATCTACATCTTCACGAGCATGCGAAATTTGCACTG
GAATGCGGTGTGGAAAGCGCTTTAATTGCAATGGATGGCGATATAATTGAGATATCTTCCACGTCCGGTGCACGCAAGGT
CGATCAGACAGAAGTTGGCTTCTGGTGTGTGGATAATGATAGGTTACAACATCCTGACAGTCACGTTATCAAGACAAGGA
GGAAGTTGCAATTAAGTGGAATGATTTTGGTAATCCTTGTGATGAACAAAAAAGGAAAATCACTAAAGAGGCCTACTATT
GTTTCATTTGGTTATAGCGAGGAAGGAGGATGGAAGGAAAATGCCTTGGCTTCGATCGAGAGGAGCTTGAAAACGGGTAA
AAATAGTGATTTTAGGGCAGTCACGAAGACAGTGAGGAAGATTGTGCGTGGTTCACTGGCGAGCAGGATAAAGATTCCAT
TGATAGAAGTGCAAATAGAAAGGGTATAG

Upstream 100 bases:

>100_bases
TTCACTGAAAAGCTTGTAGGGAATATTCGTGGTGTGGTTTTTCTGGGAATGCTTGCTTAAGACACAAGTATAGTTAGAAA
GTAGATATTGTTGGTGATAA

Downstream 100 bases:

>100_bases
CATGCTACTTCTCCGGTGGAAGAGGTTTTGGTTTTTATCATTAGGCATTCTACTTTTTTCTGGAGTTGTTTCGTTGATGT
TATTTAATCTCAGTGAGAGT

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MTDNNLIFLPLGGTGEIGMNVTLYGYKGRWIMIDCGAGFADAELPGIDIVVADISFIEERKDDLLAIIITHIHEDHCGAL
PYLWDRLAVPVYTTQFTANFLLKKIGRDKVQFPIHVVEPGKLLHLGDFTLEFINMTHSVPEMNAIAIHTADKVVIHSGDW
KIDDDPVVGKTCDFKRLEELSEKGVLAMVCDSTNVFSHGRSDSESSLREPLMEVISSASGACVVTLFSSNIARIETVTRI
ANEYGKTVVVLGRSLLSVISAAKETGYLKDLNYIDEIGLAHYSGSRKSLIILATGCQGDELAAVNRLSQGTHNSFAINAD
DTIIFSSKMIPGNEKRIAKMINRFIAVGVNVVTERTHSVHVSGHPYRDELKQLYQLLKPKILIPVHGENLHLHEHAKFAL
ECGVESALIAMDGDIIEISSTSGARKVDQTEVGFWCVDNDRLQHPDSHVIKTRRKLQLSGMILVILVMNKKGKSLKRPTI
VSFGYSEEGGWKENALASIERSLKTGKNSDFRAVTKTVRKIVRGSLASRIKIPLIEVQIERV

Sequences:

>Translated_542_residues
MTDNNLIFLPLGGTGEIGMNVTLYGYKGRWIMIDCGAGFADAELPGIDIVVADISFIEERKDDLLAIIITHIHEDHCGAL
PYLWDRLAVPVYTTQFTANFLLKKIGRDKVQFPIHVVEPGKLLHLGDFTLEFINMTHSVPEMNAIAIHTADKVVIHSGDW
KIDDDPVVGKTCDFKRLEELSEKGVLAMVCDSTNVFSHGRSDSESSLREPLMEVISSASGACVVTLFSSNIARIETVTRI
ANEYGKTVVVLGRSLLSVISAAKETGYLKDLNYIDEIGLAHYSGSRKSLIILATGCQGDELAAVNRLSQGTHNSFAINAD
DTIIFSSKMIPGNEKRIAKMINRFIAVGVNVVTERTHSVHVSGHPYRDELKQLYQLLKPKILIPVHGENLHLHEHAKFAL
ECGVESALIAMDGDIIEISSTSGARKVDQTEVGFWCVDNDRLQHPDSHVIKTRRKLQLSGMILVILVMNKKGKSLKRPTI
VSFGYSEEGGWKENALASIERSLKTGKNSDFRAVTKTVRKIVRGSLASRIKIPLIEVQIERV
>Mature_541_residues
TDNNLIFLPLGGTGEIGMNVTLYGYKGRWIMIDCGAGFADAELPGIDIVVADISFIEERKDDLLAIIITHIHEDHCGALP
YLWDRLAVPVYTTQFTANFLLKKIGRDKVQFPIHVVEPGKLLHLGDFTLEFINMTHSVPEMNAIAIHTADKVVIHSGDWK
IDDDPVVGKTCDFKRLEELSEKGVLAMVCDSTNVFSHGRSDSESSLREPLMEVISSASGACVVTLFSSNIARIETVTRIA
NEYGKTVVVLGRSLLSVISAAKETGYLKDLNYIDEIGLAHYSGSRKSLIILATGCQGDELAAVNRLSQGTHNSFAINADD
TIIFSSKMIPGNEKRIAKMINRFIAVGVNVVTERTHSVHVSGHPYRDELKQLYQLLKPKILIPVHGENLHLHEHAKFALE
CGVESALIAMDGDIIEISSTSGARKVDQTEVGFWCVDNDRLQHPDSHVIKTRRKLQLSGMILVILVMNKKGKSLKRPTIV
SFGYSEEGGWKENALASIERSLKTGKNSDFRAVTKTVRKIVRGSLASRIKIPLIEVQIERV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59876; Mature: 59745

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNLIFLPLGGTGEIGMNVTLYGYKGRWIMIDCGAGFADAELPGIDIVVADISFIEER
CCCCCEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHH
KDDLLAIIITHIHEDHCGALPYLWDRLAVPVYTTQFTANFLLKKIGRDKVQFPIHVVEPG
CCCEEEEEEEHHCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCC
KLLHLGDFTLEFINMTHSVPEMNAIAIHTADKVVIHSGDWKIDDDPVVGKTCDFKRLEEL
CEEEECCHHEEEHHHHCCCCCCCEEEEEECCEEEEECCCCEECCCCCCCCCCCHHHHHHH
SEKGVLAMVCDSTNVFSHGRSDSESSLREPLMEVISSASGACVVTLFSSNIARIETVTRI
HHCCEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
ANEYGKTVVVLGRSLLSVISAAKETGYLKDLNYIDEIGLAHYSGSRKSLIILATGCQGDE
HHHHCCEEEEHHHHHHHHHHHHHHCCCHHCCCHHHHHCCCEECCCCCEEEEEEECCCCCH
LAAVNRLSQGTHNSFAINADDTIIFSSKMIPGNEKRIAKMINRFIAVGVNVVTERTHSVH
HHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEE
VSGHPYRDELKQLYQLLKPKILIPVHGENLHLHEHAKFALECGVESALIAMDGDIIEISS
ECCCCCHHHHHHHHHHHCCEEEEEECCCEEEEHHHHHHHHHCCCCEEEEEECCCEEEEEC
TSGARKVDQTEVGFWCVDNDRLQHPDSHVIKTRRKLQLSGMILVILVMNKKGKSLKRPTI
CCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEECCEEEEEEEECCCCCCCCCCEE
VSFGYSEEGGWKENALASIERSLKTGKNSDFRAVTKTVRKIVRGSLASRIKIPLIEVQIE
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECEEEEEEEE
RV
CC
>Mature Secondary Structure 
TDNNLIFLPLGGTGEIGMNVTLYGYKGRWIMIDCGAGFADAELPGIDIVVADISFIEER
CCCCEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHH
KDDLLAIIITHIHEDHCGALPYLWDRLAVPVYTTQFTANFLLKKIGRDKVQFPIHVVEPG
CCCEEEEEEEHHCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCC
KLLHLGDFTLEFINMTHSVPEMNAIAIHTADKVVIHSGDWKIDDDPVVGKTCDFKRLEEL
CEEEECCHHEEEHHHHCCCCCCCEEEEEECCEEEEECCCCEECCCCCCCCCCCHHHHHHH
SEKGVLAMVCDSTNVFSHGRSDSESSLREPLMEVISSASGACVVTLFSSNIARIETVTRI
HHCCEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
ANEYGKTVVVLGRSLLSVISAAKETGYLKDLNYIDEIGLAHYSGSRKSLIILATGCQGDE
HHHHCCEEEEHHHHHHHHHHHHHHCCCHHCCCHHHHHCCCEECCCCCEEEEEEECCCCCH
LAAVNRLSQGTHNSFAINADDTIIFSSKMIPGNEKRIAKMINRFIAVGVNVVTERTHSVH
HHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEE
VSGHPYRDELKQLYQLLKPKILIPVHGENLHLHEHAKFALECGVESALIAMDGDIIEISS
ECCCCCHHHHHHHHHHHCCEEEEEECCCEEEEHHHHHHHHHCCCCEEEEEECCCEEEEEC
TSGARKVDQTEVGFWCVDNDRLQHPDSHVIKTRRKLQLSGMILVILVMNKKGKSLKRPTI
CCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEECCEEEEEEEECCCCCCCCCCEE
VSFGYSEEGGWKENALASIERSLKTGKNSDFRAVTKTVRKIVRGSLASRIKIPLIEVQIE
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEECEEEEEEEE
RV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]