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The map label for this gene is tlyC [H]

Identifier: 88608605

GI number: 88608605

Start: 268330

End: 269088

Strand: Direct

Name: tlyC [H]

Synonym: NSE_0327

Alternate gene names: 88608605

Gene position: 268330-269088 (Clockwise)

Preceding gene: 88608485

Following gene: 88608528

Centisome position: 31.24

GC content: 42.82

Gene sequence:

>759_bases
TTGTTTCGTCCCATATTTAGTTTTCTAAAAAAGTTCGTTGCATGGAAGCGGAGGGATGTGTCTGCTCAGGATGGTTCTTT
CCTTGCAAAGTTAGACAGCATATACGTAGAGGACATAATGGTTGAGCGTTCTAAAATTGTTGCGCTTGACGTTCGTACAA
TGGGTGAAGGATTGCTAGAAGTCCTGAAGGGTATTAGCCACAGTCGGGTACCCGTCTTTGATGGTAATTTAGACAAAATA
GTTGGGTTTATTCACGTAAAGGATGTGTTGAACCGTATGGGTGCTCCTTTCAATATAAGGAGTGCGTTGCGCAAAATTGT
ATGTGTTCCACCTTCGATGAAGGCCTCTGGATTGCTGATGGAAATGAAAGCTGCTCGTGTTCATGTAGCGGTGGTTGTCG
ATGAGTTCGGTGCGACTGTGGGTGTTGTTACAATGACAGACATTGTTGAACAAATACTTGGAGATATTCAGGACGAACAT
GGGGTTGATGCTGAGCCATCTTTTCTTCGTGTTGGTAGCGATAAATTTGAAGTCTCAACCGGGATTGAGATGAAAGAATT
TCTTGATAAATCTGGTCTAGAATTAAAAGCGGGTCATGGTTCCAGGACTTTAGGTGGTTACATATTGAGTATTGCTGGAA
AAGTTCCCTCGGTTGGGGACGTTGTATCTTCCCCTGAAGGAGTGGAGTTTACAATCTTAGATGCAGATAACAAAAAGATC
GGGGTAGTTTTAGTTGATGCTTCTCGCATTGAGAACTAG

Upstream 100 bases:

>100_bases
CTAGGTGATTTCTGCAGGGTGTGTTCTTCAGAGAATTGTTCGGTTTCTCAGATTTACAAAGCATTTTTTTTAGATTATAA
TATCCCATCGTTTATGTGCC

Downstream 100 bases:

>100_bases
TCTGGAGTGTTTTTTGTTTGTCAGTTTTGGTACACGGTTTTTCCTGTGACATGTTGTTCTTGCATTGGGTGTTATAATAG
TTAGATGGAGTGCGATTAAC

Product: CBS/transporter associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFRPIFSFLKKFVAWKRRDVSAQDGSFLAKLDSIYVEDIMVERSKIVALDVRTMGEGLLEVLKGISHSRVPVFDGNLDKI
VGFIHVKDVLNRMGAPFNIRSALRKIVCVPPSMKASGLLMEMKAARVHVAVVVDEFGATVGVVTMTDIVEQILGDIQDEH
GVDAEPSFLRVGSDKFEVSTGIEMKEFLDKSGLELKAGHGSRTLGGYILSIAGKVPSVGDVVSSPEGVEFTILDADNKKI
GVVLVDASRIEN

Sequences:

>Translated_252_residues
MFRPIFSFLKKFVAWKRRDVSAQDGSFLAKLDSIYVEDIMVERSKIVALDVRTMGEGLLEVLKGISHSRVPVFDGNLDKI
VGFIHVKDVLNRMGAPFNIRSALRKIVCVPPSMKASGLLMEMKAARVHVAVVVDEFGATVGVVTMTDIVEQILGDIQDEH
GVDAEPSFLRVGSDKFEVSTGIEMKEFLDKSGLELKAGHGSRTLGGYILSIAGKVPSVGDVVSSPEGVEFTILDADNKKI
GVVLVDASRIEN
>Mature_252_residues
MFRPIFSFLKKFVAWKRRDVSAQDGSFLAKLDSIYVEDIMVERSKIVALDVRTMGEGLLEVLKGISHSRVPVFDGNLDKI
VGFIHVKDVLNRMGAPFNIRSALRKIVCVPPSMKASGLLMEMKAARVHVAVVVDEFGATVGVVTMTDIVEQILGDIQDEH
GVDAEPSFLRVGSDKFEVSTGIEMKEFLDKSGLELKAGHGSRTLGGYILSIAGKVPSVGDVVSSPEGVEFTILDADNKKI
GVVLVDASRIEN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=181, Percent_Identity=29.8342541436464, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786879, Length=208, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082033, Length=198, Percent_Identity=26.7676767676768, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790664, Length=233, Percent_Identity=26.1802575107296, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788119, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693175, Length=155, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 27418; Mature: 27418

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPIFSFLKKFVAWKRRDVSAQDGSFLAKLDSIYVEDIMVERSKIVALDVRTMGEGLLE
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHH
VLKGISHSRVPVFDGNLDKIVGFIHVKDVLNRMGAPFNIRSALRKIVCVPPSMKASGLLM
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCHHE
EMKAARVHVAVVVDEFGATVGVVTMTDIVEQILGDIQDEHGVDAEPSFLRVGSDKFEVST
EEHHHEEEEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEC
GIEMKEFLDKSGLELKAGHGSRTLGGYILSIAGKVPSVGDVVSSPEGVEFTILDADNKKI
CCHHHHHHCCCCCEEECCCCCCCHHHHHEEECCCCCCCHHHHCCCCCCEEEEEECCCCEE
GVVLVDASRIEN
EEEEEECCCCCC
>Mature Secondary Structure
MFRPIFSFLKKFVAWKRRDVSAQDGSFLAKLDSIYVEDIMVERSKIVALDVRTMGEGLLE
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHH
VLKGISHSRVPVFDGNLDKIVGFIHVKDVLNRMGAPFNIRSALRKIVCVPPSMKASGLLM
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCHHE
EMKAARVHVAVVVDEFGATVGVVTMTDIVEQILGDIQDEHGVDAEPSFLRVGSDKFEVST
EEHHHEEEEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEC
GIEMKEFLDKSGLELKAGHGSRTLGGYILSIAGKVPSVGDVVSSPEGVEFTILDADNKKI
CCHHHHHHCCCCCEEECCCCCCCHHHHHEEECCCCCCCHHHHCCCCCCEEEEEECCCCEE
GVVLVDASRIEN
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA