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The map label for this gene is divJ [H]

Identifier: 88608550

GI number: 88608550

Start: 2237

End: 3580

Strand: Reverse

Name: divJ [H]

Synonym: NSE_0003

Alternate gene names: 88608550

Gene position: 3580-2237 (Counterclockwise)

Preceding gene: 88608833

Following gene: NA

Centisome position: 0.42

GC content: 35.42

Gene sequence:

>1344_bases
ATGTTTAACTATATAAAGTCGTTCATCCTCATTGTAGTGACAATACTACTGACTTCTTTCCTTGGGTATATAAAGACAGA
AAAAACCCTTCTCGAAAGCAGCACAGAGAGGAATGCGGTGAATATTAGGAATATTTTTAATAGACTAATATGGGAAAAAT
ACTCCTTTATGCTTGAAATGTATGACTTTGAGCCTACAAAAATGTATGAAAAGCCTCAATTCATGTACTTTGAGAGCGAA
GCGAAGTTACTTTTTGAACCACTGGATGTTATTCAAGTTGAAATATTTTACAAAGGTGAAACAAGAGTTTTTAGTCTCAA
CAAATATCTAGAACATGCACACCATCCGTATAATCATGACCTAAATAACAATATTTCTTCCACCTCTATCGACAACGCGG
GAAATATAGTAGTCACAGTGGCTTTGAACCCAGAAGAAAATCCCCCGTCGGTTATTGAAATTACATACGATGCAAAGAGC
CTTATAAGGCCTTTCCGCATTACATGGATAGGCTTCACACTTGTCGTATTGTTCATTTGCTCATCCTTATTTTTCTGGAG
CGTAATGAAAATCAGGGAAAGCTCTAAGGTCTTGAACGAACAGTTTTCGATAAACACGAAACTAAAAAAAGCCAAAGAAA
GTATAGAAGAAATAAGTTCCCAAAAATCACAATTTCTAGCGAATGTTAGTCACGAACTAAAAACACCTTTAAACGCAATA
ATAGGTTTCTCAGATCTGATACGCACAGCAGAAGTGCTTGGTACTGAACATAGAGAATATGCAAATGATATCTATTATTC
AGGGAATCACCTGTTAAATTTGATTAACGACATTCTCGATTTTTCAAAGTCAGAGTTAAACAACTTGGAAATAAAACCAA
CATTGTTTGATTTAGTACGCTTGACTGAGACTTGTATCAGGATGACAACAACTAAAAGAAAAGAGATAAAAATAGTGAAG
AGTTTCTTTTCAAATAAGATACTTATCAAAAGCGATCATAAGAGGGTAAAACAAGTAATCCTAAATATACTTTCAAACTC
GATAAAATTCACGAATGAAGATGGCTTAATAAGAATTTCTATAATCAGATTACCTTCAGAGATTGAAATTGAAATTTCAG
ATAATGGTGTTGGTATACCAGAAAAAGATATAGCAAAGGCACTCTCTGTATTTGGCCAATCAAATACGGAGCTATCAAGA
AAATACGACGGAGCTGGAATAGGGTTACCACTTAGCAAGAAACTGGTAGAGTTGATGGGTGGAGTATTCGAGATTGAAAG
CAAGGAGGGAAGCGGCACCGTCGTTAAAATAAGGCTTCCGTATAGAGAAAGCAACGCCGCTTAA

Upstream 100 bases:

>100_bases
AAAAGATTCTATCCCTCCCCCAACTACTACGTAATCGTACATCTCTGTGATTTAAACAAAAAGTTATATACTTTAATCGC
TAACTTGATCGCTACTCAAA

Downstream 100 bases:

>100_bases
GAGACAAATCGGTTAGTTCTTTACTAGAGATTTCTAGATGCAGCCTTGCAACTGTATGGAACAAAATCATACCCTCCCGC
TTTAGCTTCTGAGAAACCCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MFNYIKSFILIVVTILLTSFLGYIKTEKTLLESSTERNAVNIRNIFNRLIWEKYSFMLEMYDFEPTKMYEKPQFMYFESE
AKLLFEPLDVIQVEIFYKGETRVFSLNKYLEHAHHPYNHDLNNNISSTSIDNAGNIVVTVALNPEENPPSVIEITYDAKS
LIRPFRITWIGFTLVVLFICSSLFFWSVMKIRESSKVLNEQFSINTKLKKAKESIEEISSQKSQFLANVSHELKTPLNAI
IGFSDLIRTAEVLGTEHREYANDIYYSGNHLLNLINDILDFSKSELNNLEIKPTLFDLVRLTETCIRMTTTKRKEIKIVK
SFFSNKILIKSDHKRVKQVILNILSNSIKFTNEDGLIRISIIRLPSEIEIEISDNGVGIPEKDIAKALSVFGQSNTELSR
KYDGAGIGLPLSKKLVELMGGVFEIESKEGSGTVVKIRLPYRESNAA

Sequences:

>Translated_447_residues
MFNYIKSFILIVVTILLTSFLGYIKTEKTLLESSTERNAVNIRNIFNRLIWEKYSFMLEMYDFEPTKMYEKPQFMYFESE
AKLLFEPLDVIQVEIFYKGETRVFSLNKYLEHAHHPYNHDLNNNISSTSIDNAGNIVVTVALNPEENPPSVIEITYDAKS
LIRPFRITWIGFTLVVLFICSSLFFWSVMKIRESSKVLNEQFSINTKLKKAKESIEEISSQKSQFLANVSHELKTPLNAI
IGFSDLIRTAEVLGTEHREYANDIYYSGNHLLNLINDILDFSKSELNNLEIKPTLFDLVRLTETCIRMTTTKRKEIKIVK
SFFSNKILIKSDHKRVKQVILNILSNSIKFTNEDGLIRISIIRLPSEIEIEISDNGVGIPEKDIAKALSVFGQSNTELSR
KYDGAGIGLPLSKKLVELMGGVFEIESKEGSGTVVKIRLPYRESNAA
>Mature_447_residues
MFNYIKSFILIVVTILLTSFLGYIKTEKTLLESSTERNAVNIRNIFNRLIWEKYSFMLEMYDFEPTKMYEKPQFMYFESE
AKLLFEPLDVIQVEIFYKGETRVFSLNKYLEHAHHPYNHDLNNNISSTSIDNAGNIVVTVALNPEENPPSVIEITYDAKS
LIRPFRITWIGFTLVVLFICSSLFFWSVMKIRESSKVLNEQFSINTKLKKAKESIEEISSQKSQFLANVSHELKTPLNAI
IGFSDLIRTAEVLGTEHREYANDIYYSGNHLLNLINDILDFSKSELNNLEIKPTLFDLVRLTETCIRMTTTKRKEIKIVK
SFFSNKILIKSDHKRVKQVILNILSNSIKFTNEDGLIRISIIRLPSEIEIEISDNGVGIPEKDIAKALSVFGQSNTELSR
KYDGAGIGLPLSKKLVELMGGVFEIESKEGSGTVVKIRLPYRESNAA

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=37.1428571428571, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=35.1694915254237, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=33.920704845815, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=27.0386266094421, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790436, Length=307, Percent_Identity=23.4527687296417, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=23.5807860262009, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=23.8683127572016, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=26.9406392694064, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=23.9837398373984, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=24.2553191489362, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=297, Percent_Identity=21.5488215488215, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=21.3675213675214, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=21.3991769547325, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51218; Mature: 51218

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNYIKSFILIVVTILLTSFLGYIKTEKTLLESSTERNAVNIRNIFNRLIWEKYSFMLEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YDFEPTKMYEKPQFMYFESEAKLLFEPLDVIQVEIFYKGETRVFSLNKYLEHAHHPYNHD
HCCCCHHHCCCCCEEEEECCCHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHCCCCCCCC
LNNNISSTSIDNAGNIVVTVALNPEENPPSVIEITYDAKSLIRPFRITWIGFTLVVLFIC
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECHHHHCCHHHHHHHHHHHHHHHHH
SSLFFWSVMKIRESSKVLNEQFSINTKLKKAKESIEEISSQKSQFLANVSHELKTPLNAI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
IGFSDLIRTAEVLGTEHREYANDIYYSGNHLLNLINDILDFSKSELNNLEIKPTLFDLVR
HHHHHHHHHHHHHCCHHHHHHHHHEECCHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHH
LTETCIRMTTTKRKEIKIVKSFFSNKILIKSDHKRVKQVILNILSNSIKFTNEDGLIRIS
HHHHHHHHHHCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCEEECCCCEEEEE
IIRLPSEIEIEISDNGVGIPEKDIAKALSVFGQSNTELSRKYDGAGIGLPLSKKLVELMG
EEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHCC
GVFEIESKEGSGTVVKIRLPYRESNAA
CEEEEECCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MFNYIKSFILIVVTILLTSFLGYIKTEKTLLESSTERNAVNIRNIFNRLIWEKYSFMLEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YDFEPTKMYEKPQFMYFESEAKLLFEPLDVIQVEIFYKGETRVFSLNKYLEHAHHPYNHD
HCCCCHHHCCCCCEEEEECCCHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHCCCCCCCC
LNNNISSTSIDNAGNIVVTVALNPEENPPSVIEITYDAKSLIRPFRITWIGFTLVVLFIC
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECHHHHCCHHHHHHHHHHHHHHHHH
SSLFFWSVMKIRESSKVLNEQFSINTKLKKAKESIEEISSQKSQFLANVSHELKTPLNAI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
IGFSDLIRTAEVLGTEHREYANDIYYSGNHLLNLINDILDFSKSELNNLEIKPTLFDLVR
HHHHHHHHHHHHHCCHHHHHHHHHEECCHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHH
LTETCIRMTTTKRKEIKIVKSFFSNKILIKSDHKRVKQVILNILSNSIKFTNEDGLIRIS
HHHHHHHHHHCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCEEECCCCEEEEE
IIRLPSEIEIEISDNGVGIPEKDIAKALSVFGQSNTELSRKYDGAGIGLPLSKKLVELMG
EEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHCC
GVFEIESKEGSGTVVKIRLPYRESNAA
CEEEEECCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]