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The map label for this gene is ftsK [H]

Identifier: 88608510

GI number: 88608510

Start: 570007

End: 572436

Strand: Direct

Name: ftsK [H]

Synonym: NSE_0650

Alternate gene names: 88608510

Gene position: 570007-572436 (Clockwise)

Preceding gene: 88608067

Following gene: 88608160

Centisome position: 66.36

GC content: 41.15

Gene sequence:

>2430_bases
ATGGCACAAAAAATCAAAAACTTTCTTTACATACTTTCATCAATCACGTGTAGACTTGTATTGCTTTTCCTAATGGTTTG
CAGCTTAAAAAGTGGTGAGGAGATACCTTCCTTTACTACTGCAGCAGAGTTACATAGCAGCAAATTTATATTTTTCGGTC
GGTCAGCAGCAACTTATCTAATGACTCTAATTGGACTTGGATTCTACCCACTCTGTACGCTACTTGTGTGCAGTTTCATT
CTTTCCAGAGAAAAAGTCATTCTTTTAAGCGTGTTAATTCTTATATTGATCACGTTGTTATCAAAGGTCCCACCGTCTGA
TGAATGGCTATTCGGCTCATACGGAGGAATCATGGGTTCATTACTCGCGAGTTATTTGGACCACCCACACGCGTCACACT
TTTTGATAGCGCTGACAATCATTCTAAGCTTATGGATTTTCAATTTCCTCACGATAAGGAAGATAAAAAAAGCTATAAGA
AAAGCATTTTGCACTGTGAAAGTGCTTGCCTCGTTACCGCTGTTACTCCTGAAGAAGAAATTAAAATCCAAGTCGCACGA
TGATAAGGGCAACGCGGTTACACAAAAAGGCCACATACATAATGAGACACCGGAAGAAGACCTTCCTATAAAGTGCACAT
ACAATTTCATCAAAGAGAAGGAACCACATGTAAATGAAGAAGATAAAGGCCAAACCTTCTCTGAAATAAATAAAAAAGCT
TCCCATGAAGTTTTAACACCTACAATTAAACCCAAGAAAAAGCCATCACTCAAGGAGAGGATGGAGTCATCAGGTACAAA
ATCATTTTCACAGAAGGACTCTATTCCGGCTCATGAAGAACGTATCGAAACCGAAAAAACAAGCAAGTCTTCCTCTCTCA
AAGAAAGCTCCATCATGAGAAAGTTTACGTCTCATGAAATCAGGAAGAAATTCAAATCCGGTACTTTTGCTATCGAGACA
AACACAATACCCCCGCTGGAGCTACTTAAGGAACGTAGCCCTGAGCCCAAACAACTAGAAGATACACAAAAAGAAGGTGA
GAATCTAAGAAAAGTACTAGAAGACTTTAAAATAGAGTGCAAAATGGTCGAGATCACAGTTGGACCTGTAGTGACGCTGT
ACGAACTACAGCCGGCAGCTGGCATAAAATCATCCTCAATCATTGCACTTTCAGCAGATGTTGCAAGAACAATGAGTGCC
ATCTCAGCAAGAATCTCGATCATACCAGGACGAAGCGTAATTGGGGTAGAGCTTCCAAATAAGCACAGGGAAGTTGTGCT
TTTGCGAGAAATTTTAGAATCGGGCGAGTATCAAGCAGCTGATAAGGTTCTCCCAATAGCACTTGGCAAAAGTATTAGCG
GTGAACCAGTAGTCGTCGACCTCGCAAAGATGCCGCATCTTTTAGTTGCAGGCACAACAGGATCCGGGAAATCCGTGGCA
ATAAACACAATGATCCTCTCATTGATATACAAACTTGAACCCGACAAATGCAAGCTCATAATGATAGACCCAAAAATGCT
TGAGCTGTCCATTTACAATGATATTCCTCATTTGCTTTCGCCTGTTGTAACAGACCCTAAAAAGGCTGTGGTCGCACTAA
AGTGGGTAGTCAAGGAAATGGAAGAACGCTACCGACTCATGACAAAACTCTCTGTGAGGAATATTGAGAGCTACAACAAA
AAAGCTGAGGAGTTTATAAAGCGAGGCAAGCTTTTTGAATATGAAGAAACAATTGGAATAGATCCCACAACAAAAGAGAA
ACTCACTCGTACACAAAGCATTGAACTCGAGAAGTTACCCTTTATCGTAGTTGTAGTTGATGAGATGGCAGATTTAATGC
TCGTTGCAGGGAAGGAAATTGAAACATCAATACAAAGACTAGCGCAAATGGCTAGAGCTTCGGGAATCCATATAATAATG
GCAACACAGCGTCCGTCGGTGGACATCATCACTGGTGTTATTAAGGCAAACTTCCCAACTAGAATCAGTTTCGCAGTTAC
CTCAAAAATTGATAGTAGGACTATCCTTGGTGAACAGGGAGCAGAGCAACTTCTTGGACGTGGTGACATGTTATATATGG
CTGCTGGCCAAGCACCTGTGAGAATACACGGACCATATGTGAGCGATCCCGAAGTAGAGAAAATTGCAGAATATTTAAAA
AAATCTGGGAGTCCGCAGTACAACGAAAATATCGTGCTTGAAGAGGAATCAGATGAAGATACAGCAGTCAGTGTTGCTGG
TGGTGATGATTTCAATTCTCTCTACGCGCAGGCAATAGAAATAGTAAGGAAAGATAATAAGGTCTCAATCAGTTACATCC
AAAGACGACTCTCACTTGGATATAACAAGGCTGCAAAACTCGTTGAAAAGATGGAAGAGGAAGGTGTTGTGAGCCCGCCA
AATAATGCAGGAAAAAGAACTCTCCTTTAG

Upstream 100 bases:

>100_bases
CTAAGGGCTTTTACCGATGCCTCTTTCGGTATTTCACTCTCTTAAAGTGCTCTTCAATCAATGCTACACTGCCCAGTATC
AAAGAAAGAGCTCGGTGAGG

Downstream 100 bases:

>100_bases
CAAACTTTTGCACTAACAATAAGAATAAGCTTCACAGGAGCAAGAGTCACTCGCTGTTTAGAGAGAATTAAGGCACTCGG
TCAATCTTGCTTTCACCGCT

Product: putative cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 809; Mature: 808

Protein sequence:

>809_residues
MAQKIKNFLYILSSITCRLVLLFLMVCSLKSGEEIPSFTTAAELHSSKFIFFGRSAATYLMTLIGLGFYPLCTLLVCSFI
LSREKVILLSVLILILITLLSKVPPSDEWLFGSYGGIMGSLLASYLDHPHASHFLIALTIILSLWIFNFLTIRKIKKAIR
KAFCTVKVLASLPLLLLKKKLKSKSHDDKGNAVTQKGHIHNETPEEDLPIKCTYNFIKEKEPHVNEEDKGQTFSEINKKA
SHEVLTPTIKPKKKPSLKERMESSGTKSFSQKDSIPAHEERIETEKTSKSSSLKESSIMRKFTSHEIRKKFKSGTFAIET
NTIPPLELLKERSPEPKQLEDTQKEGENLRKVLEDFKIECKMVEITVGPVVTLYELQPAAGIKSSSIIALSADVARTMSA
ISARISIIPGRSVIGVELPNKHREVVLLREILESGEYQAADKVLPIALGKSISGEPVVVDLAKMPHLLVAGTTGSGKSVA
INTMILSLIYKLEPDKCKLIMIDPKMLELSIYNDIPHLLSPVVTDPKKAVVALKWVVKEMEERYRLMTKLSVRNIESYNK
KAEEFIKRGKLFEYEETIGIDPTTKEKLTRTQSIELEKLPFIVVVVDEMADLMLVAGKEIETSIQRLAQMARASGIHIIM
ATQRPSVDIITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGRGDMLYMAAGQAPVRIHGPYVSDPEVEKIAEYLK
KSGSPQYNENIVLEEESDEDTAVSVAGGDDFNSLYAQAIEIVRKDNKVSISYIQRRLSLGYNKAAKLVEKMEEEGVVSPP
NNAGKRTLL

Sequences:

>Translated_809_residues
MAQKIKNFLYILSSITCRLVLLFLMVCSLKSGEEIPSFTTAAELHSSKFIFFGRSAATYLMTLIGLGFYPLCTLLVCSFI
LSREKVILLSVLILILITLLSKVPPSDEWLFGSYGGIMGSLLASYLDHPHASHFLIALTIILSLWIFNFLTIRKIKKAIR
KAFCTVKVLASLPLLLLKKKLKSKSHDDKGNAVTQKGHIHNETPEEDLPIKCTYNFIKEKEPHVNEEDKGQTFSEINKKA
SHEVLTPTIKPKKKPSLKERMESSGTKSFSQKDSIPAHEERIETEKTSKSSSLKESSIMRKFTSHEIRKKFKSGTFAIET
NTIPPLELLKERSPEPKQLEDTQKEGENLRKVLEDFKIECKMVEITVGPVVTLYELQPAAGIKSSSIIALSADVARTMSA
ISARISIIPGRSVIGVELPNKHREVVLLREILESGEYQAADKVLPIALGKSISGEPVVVDLAKMPHLLVAGTTGSGKSVA
INTMILSLIYKLEPDKCKLIMIDPKMLELSIYNDIPHLLSPVVTDPKKAVVALKWVVKEMEERYRLMTKLSVRNIESYNK
KAEEFIKRGKLFEYEETIGIDPTTKEKLTRTQSIELEKLPFIVVVVDEMADLMLVAGKEIETSIQRLAQMARASGIHIIM
ATQRPSVDIITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGRGDMLYMAAGQAPVRIHGPYVSDPEVEKIAEYLK
KSGSPQYNENIVLEEESDEDTAVSVAGGDDFNSLYAQAIEIVRKDNKVSISYIQRRLSLGYNKAAKLVEKMEEEGVVSPP
NNAGKRTLL
>Mature_808_residues
AQKIKNFLYILSSITCRLVLLFLMVCSLKSGEEIPSFTTAAELHSSKFIFFGRSAATYLMTLIGLGFYPLCTLLVCSFIL
SREKVILLSVLILILITLLSKVPPSDEWLFGSYGGIMGSLLASYLDHPHASHFLIALTIILSLWIFNFLTIRKIKKAIRK
AFCTVKVLASLPLLLLKKKLKSKSHDDKGNAVTQKGHIHNETPEEDLPIKCTYNFIKEKEPHVNEEDKGQTFSEINKKAS
HEVLTPTIKPKKKPSLKERMESSGTKSFSQKDSIPAHEERIETEKTSKSSSLKESSIMRKFTSHEIRKKFKSGTFAIETN
TIPPLELLKERSPEPKQLEDTQKEGENLRKVLEDFKIECKMVEITVGPVVTLYELQPAAGIKSSSIIALSADVARTMSAI
SARISIIPGRSVIGVELPNKHREVVLLREILESGEYQAADKVLPIALGKSISGEPVVVDLAKMPHLLVAGTTGSGKSVAI
NTMILSLIYKLEPDKCKLIMIDPKMLELSIYNDIPHLLSPVVTDPKKAVVALKWVVKEMEERYRLMTKLSVRNIESYNKK
AEEFIKRGKLFEYEETIGIDPTTKEKLTRTQSIELEKLPFIVVVVDEMADLMLVAGKEIETSIQRLAQMARASGIHIIMA
TQRPSVDIITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGRGDMLYMAAGQAPVRIHGPYVSDPEVEKIAEYLKK
SGSPQYNENIVLEEESDEDTAVSVAGGDDFNSLYAQAIEIVRKDNKVSISYIQRRLSLGYNKAAKLVEKMEEEGVVSPPN
NAGKRTLL

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=498, Percent_Identity=49.1967871485944, Blast_Score=463, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 90115; Mature: 89983

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKIKNFLYILSSITCRLVLLFLMVCSLKSGEEIPSFTTAAELHSSKFIFFGRSAATYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHH
MTLIGLGFYPLCTLLVCSFILSREKVILLSVLILILITLLSKVPPSDEWLFGSYGGIMGS
HHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHH
LLASYLDHPHASHFLIALTIILSLWIFNFLTIRKIKKAIRKAFCTVKVLASLPLLLLKKK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSKSHDDKGNAVTQKGHIHNETPEEDLPIKCTYNFIKEKEPHVNEEDKGQTFSEINKKA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHH
SHEVLTPTIKPKKKPSLKERMESSGTKSFSQKDSIPAHEERIETEKTSKSSSLKESSIMR
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KFTSHEIRKKFKSGTFAIETNTIPPLELLKERSPEPKQLEDTQKEGENLRKVLEDFKIEC
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
KMVEITVGPVVTLYELQPAAGIKSSSIIALSADVARTMSAISARISIIPGRSVIGVELPN
EEEEEEECCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCC
KHREVVLLREILESGEYQAADKVLPIALGKSISGEPVVVDLAKMPHLLVAGTTGSGKSVA
CCHHHHHHHHHHHCCCCCHHCCEEEHEECCCCCCCCEEEEHHHCCEEEEEECCCCCCCCH
INTMILSLIYKLEPDKCKLIMIDPKMLELSIYNDIPHLLSPVVTDPKKAVVALKWVVKEM
HHHHHHHHHHHCCCCCEEEEEECCCEEEEEEHHCCHHHHHHHHCCCHHHHHHHHHHHHHH
EERYRLMTKLSVRNIESYNKKAEEFIKRGKLFEYEETIGIDPTTKEKLTRTQSIELEKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCHHHHHHHHCCCHHHCC
FIVVVVDEMADLMLVAGKEIETSIQRLAQMARASGIHIIMATQRPSVDIITGVIKANFPT
EEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCC
RISFAVTSKIDSRTILGEQGAEQLLGRGDMLYMAAGQAPVRIHGPYVSDPEVEKIAEYLK
EEEEEEECCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHH
KSGSPQYNENIVLEEESDEDTAVSVAGGDDFNSLYAQAIEIVRKDNKVSISYIQRRLSLG
HCCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
YNKAAKLVEKMEEEGVVSPPNNAGKRTLL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQKIKNFLYILSSITCRLVLLFLMVCSLKSGEEIPSFTTAAELHSSKFIFFGRSAATYL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHH
MTLIGLGFYPLCTLLVCSFILSREKVILLSVLILILITLLSKVPPSDEWLFGSYGGIMGS
HHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHH
LLASYLDHPHASHFLIALTIILSLWIFNFLTIRKIKKAIRKAFCTVKVLASLPLLLLKKK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSKSHDDKGNAVTQKGHIHNETPEEDLPIKCTYNFIKEKEPHVNEEDKGQTFSEINKKA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHH
SHEVLTPTIKPKKKPSLKERMESSGTKSFSQKDSIPAHEERIETEKTSKSSSLKESSIMR
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KFTSHEIRKKFKSGTFAIETNTIPPLELLKERSPEPKQLEDTQKEGENLRKVLEDFKIEC
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
KMVEITVGPVVTLYELQPAAGIKSSSIIALSADVARTMSAISARISIIPGRSVIGVELPN
EEEEEEECCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHEEEECCCCEEEEECCC
KHREVVLLREILESGEYQAADKVLPIALGKSISGEPVVVDLAKMPHLLVAGTTGSGKSVA
CCHHHHHHHHHHHCCCCCHHCCEEEHEECCCCCCCCEEEEHHHCCEEEEEECCCCCCCCH
INTMILSLIYKLEPDKCKLIMIDPKMLELSIYNDIPHLLSPVVTDPKKAVVALKWVVKEM
HHHHHHHHHHHCCCCCEEEEEECCCEEEEEEHHCCHHHHHHHHCCCHHHHHHHHHHHHHH
EERYRLMTKLSVRNIESYNKKAEEFIKRGKLFEYEETIGIDPTTKEKLTRTQSIELEKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCHHHHHHHHCCCHHHCC
FIVVVVDEMADLMLVAGKEIETSIQRLAQMARASGIHIIMATQRPSVDIITGVIKANFPT
EEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCC
RISFAVTSKIDSRTILGEQGAEQLLGRGDMLYMAAGQAPVRIHGPYVSDPEVEKIAEYLK
EEEEEEECCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHH
KSGSPQYNENIVLEEESDEDTAVSVAGGDDFNSLYAQAIEIVRKDNKVSISYIQRRLSLG
HCCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
YNKAAKLVEKMEEEGVVSPPNNAGKRTLL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA