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The map label for this gene is ccmF [H]

Identifier: 88608436

GI number: 88608436

Start: 496793

End: 498628

Strand: Direct

Name: ccmF [H]

Synonym: NSE_0572

Alternate gene names: 88608436

Gene position: 496793-498628 (Clockwise)

Preceding gene: 88608642

Following gene: 88608038

Centisome position: 57.83

GC content: 37.85

Gene sequence:

>1836_bases
ATGGTACCCTCATCGTGCATATCGATGCTGACAACAATTCACTACTATCTTGGAACAATACTGCTCTTTCTCAGTCTGTT
CTCAAGTCTCGTGAGAAAACCCGGGACATTATTTTTCTTGAATTCGATCATTTTCATCATTCTTTTTCACGCACATCTAT
CAAATAATTTCCTCCTGCAAAGCGTATACTCAAGCTCCCACACAAATCTTCCACTTTATTACAAACTCGTTGCAAGCTGG
ACGACACATGAGGGATCTATGATCCTCTGGAACTGGTCACTTTCACTATATCTATTTATATTTTCAAGAAAATATAGAAA
CTCACAAATTTACCAAGCCGTTATAACAATACAATCTTACATTGCGTCCATATTTCTATTGTTCACAATTTATTCGAGTA
ATCCGTTCAAACTCTTCATTCTTGCCCCCTCTGAAGGCGCTGGGCTGAACCCGATTTTACAAGATACAGCTCTCATGATC
CATCCACCAATTCTCTATCTTGGGTATGTTGGAACCTCAATCTGTTTTTCAATTGCAATAGCGGTTTTACTCACGGGAAA
ATCTGGAAAAGAAGAGTTTAAGCTGTTGAACTTCTTCCTTCTACTCGCATTTATCTTTTTAACATCCGGTATAGCACTTG
GCGGATGGTGGTCATACAGGGAACTTGGATGGGGAGGGTTTTGGTCTTGGGACCCAGTGGAAAATATATCATTATTCCCA
TATTTAGTTATACTCGGTGCAATACACTCGTCATTTCTATCAATTAAAAAATGGAAGTCTAAAGCTCTTTCCATAGGACT
TTCGATCCTTGGATTTGTTACAGCGACATTCGGTACCTTTATCACTAGAATGGGCATTACAGATTCTCTTCACACATTTA
ACACGAACACAGAAAGTGGAATATACTTATTGATAATAACTAGCCTATTATCACTAACCTCAGCAGTTATTTTCATTGCA
AAATTCCGTACTCTTAGTAGCACCGACGTGAGCAGCAACAGCAATACAGAGTCAAGAGACTATTTGATGTCAGCACAGAG
TATTTTGTGTCTTGGATTGTTTATAGTGTTACTTTTAACAACATTTGCACCAAAGTTCTCTCAGATATTTGGCTACGATT
CCATTTACATAATGCAATCTTTTTACAACACTGTTTCTGGAGAAGTTGCTGGGACCTTAGCGGTTTGCATTTGCCTATTT
ATTGTACTCACAAGTAAGGAAAGGTGCACAAAATTCATCGTGTTAACCCTAGCTGCAATAGTACTCTCATTAGGAAATTT
CGTAAACATTCTTACTGCTTTTCTCTCGATTTCAGGGATGATGACAATGCTCAGTCTCCTGACCAAACATGTAAAAGATC
TGCAGCAAGAAGATAGCATAAAAGGGATCTTCAGAACAAAAAAGAATGCTTTCTTTCTGACGCACTTTGGATTTGGATTA
TTTCTTTACGCAGTGGCTGGATTTGCATCAAATTCATTAGAAAACAAACAATACTTTCAGATAGGAGAACAACGTATAGT
AAAGCAGCATATTATAAAGCTCACAGATTTCGACAAAATCAACAACGATCTTTTTTCCGGTATAAGGGCTACTTTTACTA
TCAACGGAAGAGCCAAACTAGAGCCAGAACTGCGATTTTATAAGTATGAAAACACTCTTAACACAGAGTCAGACACCTTC
CATTGTCTATTGAGTGATATACAAATACTAGTAACTGGGATAGACAAGACCTTGGGACTCGCAGTAGAAATTTATTATAG
AGACAAGATACAGCTAATCTGGTTGGGACTAGTGCTAATTATACTGGGGACGACACACAAGTTATTCATTCGTTAA

Upstream 100 bases:

>100_bases
GGAAAACTGCCGGACCACCGTAAAAGATAACTTATCCTTTTTTGACAGCTGGTCAACTATTTTACTTAAACAACTTCAAT
GCGTCATGTATAATCCATAG

Downstream 100 bases:

>100_bases
TCTAGGATTGATTGCACTCCAAGCGTTTCCGCTTGATCACTCTTCTCAATAGCATGCTTCACATGACCGCTTTCCATCTC
AAAACGAGTTTTCACCTCTA

Product: CcmF/CcyK/CcsA family cytochrome c biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MVPSSCISMLTTIHYYLGTILLFLSLFSSLVRKPGTLFFLNSIIFIILFHAHLSNNFLLQSVYSSSHTNLPLYYKLVASW
TTHEGSMILWNWSLSLYLFIFSRKYRNSQIYQAVITIQSYIASIFLLFTIYSSNPFKLFILAPSEGAGLNPILQDTALMI
HPPILYLGYVGTSICFSIAIAVLLTGKSGKEEFKLLNFFLLLAFIFLTSGIALGGWWSYRELGWGGFWSWDPVENISLFP
YLVILGAIHSSFLSIKKWKSKALSIGLSILGFVTATFGTFITRMGITDSLHTFNTNTESGIYLLIITSLLSLTSAVIFIA
KFRTLSSTDVSSNSNTESRDYLMSAQSILCLGLFIVLLLTTFAPKFSQIFGYDSIYIMQSFYNTVSGEVAGTLAVCICLF
IVLTSKERCTKFIVLTLAAIVLSLGNFVNILTAFLSISGMMTMLSLLTKHVKDLQQEDSIKGIFRTKKNAFFLTHFGFGL
FLYAVAGFASNSLENKQYFQIGEQRIVKQHIIKLTDFDKINNDLFSGIRATFTINGRAKLEPELRFYKYENTLNTESDTF
HCLLSDIQILVTGIDKTLGLAVEIYYRDKIQLIWLGLVLIILGTTHKLFIR

Sequences:

>Translated_611_residues
MVPSSCISMLTTIHYYLGTILLFLSLFSSLVRKPGTLFFLNSIIFIILFHAHLSNNFLLQSVYSSSHTNLPLYYKLVASW
TTHEGSMILWNWSLSLYLFIFSRKYRNSQIYQAVITIQSYIASIFLLFTIYSSNPFKLFILAPSEGAGLNPILQDTALMI
HPPILYLGYVGTSICFSIAIAVLLTGKSGKEEFKLLNFFLLLAFIFLTSGIALGGWWSYRELGWGGFWSWDPVENISLFP
YLVILGAIHSSFLSIKKWKSKALSIGLSILGFVTATFGTFITRMGITDSLHTFNTNTESGIYLLIITSLLSLTSAVIFIA
KFRTLSSTDVSSNSNTESRDYLMSAQSILCLGLFIVLLLTTFAPKFSQIFGYDSIYIMQSFYNTVSGEVAGTLAVCICLF
IVLTSKERCTKFIVLTLAAIVLSLGNFVNILTAFLSISGMMTMLSLLTKHVKDLQQEDSIKGIFRTKKNAFFLTHFGFGL
FLYAVAGFASNSLENKQYFQIGEQRIVKQHIIKLTDFDKINNDLFSGIRATFTINGRAKLEPELRFYKYENTLNTESDTF
HCLLSDIQILVTGIDKTLGLAVEIYYRDKIQLIWLGLVLIILGTTHKLFIR
>Mature_611_residues
MVPSSCISMLTTIHYYLGTILLFLSLFSSLVRKPGTLFFLNSIIFIILFHAHLSNNFLLQSVYSSSHTNLPLYYKLVASW
TTHEGSMILWNWSLSLYLFIFSRKYRNSQIYQAVITIQSYIASIFLLFTIYSSNPFKLFILAPSEGAGLNPILQDTALMI
HPPILYLGYVGTSICFSIAIAVLLTGKSGKEEFKLLNFFLLLAFIFLTSGIALGGWWSYRELGWGGFWSWDPVENISLFP
YLVILGAIHSSFLSIKKWKSKALSIGLSILGFVTATFGTFITRMGITDSLHTFNTNTESGIYLLIITSLLSLTSAVIFIA
KFRTLSSTDVSSNSNTESRDYLMSAQSILCLGLFIVLLLTTFAPKFSQIFGYDSIYIMQSFYNTVSGEVAGTLAVCICLF
IVLTSKERCTKFIVLTLAAIVLSLGNFVNILTAFLSISGMMTMLSLLTKHVKDLQQEDSIKGIFRTKKNAFFLTHFGFGL
FLYAVAGFASNSLENKQYFQIGEQRIVKQHIIKLTDFDKINNDLFSGIRATFTINGRAKLEPELRFYKYENTLNTESDTF
HCLLSDIQILVTGIDKTLGLAVEIYYRDKIQLIWLGLVLIILGTTHKLFIR

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=580, Percent_Identity=30.8620689655172, Blast_Score=245, Evalue=7e-66,
Organism=Escherichia coli, GI1790511, Length=570, Percent_Identity=27.5438596491228, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 68758; Mature: 68758

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPSSCISMLTTIHYYLGTILLFLSLFSSLVRKPGTLFFLNSIIFIILFHAHLSNNFLLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
SVYSSSHTNLPLYYKLVASWTTHEGSMILWNWSLSLYLFIFSRKYRNSQIYQAVITIQSY
HHHCCCCCCCCEEEEEEHHHCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IASIFLLFTIYSSNPFKLFILAPSEGAGLNPILQDTALMIHPPILYLGYVGTSICFSIAI
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHCCCCEEECHHHHHHHHHHHHHHHHHH
AVLLTGKSGKEEFKLLNFFLLLAFIFLTSGIALGGWWSYRELGWGGFWSWDPVENISLFP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHCCCCCCCCCCCCCCCHHHH
YLVILGAIHSSFLSIKKWKSKALSIGLSILGFVTATFGTFITRMGITDSLHTFNTNTESG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
IYLLIITSLLSLTSAVIFIAKFRTLSSTDVSSNSNTESRDYLMSAQSILCLGLFIVLLLT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFAPKFSQIFGYDSIYIMQSFYNTVSGEVAGTLAVCICLFIVLTSKERCTKFIVLTLAAI
HCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VLSLGNFVNILTAFLSISGMMTMLSLLTKHVKDLQQEDSIKGIFRTKKNAFFLTHFGFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHH
FLYAVAGFASNSLENKQYFQIGEQRIVKQHIIKLTDFDKINNDLFSGIRATFTINGRAKL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCEEC
EPELRFYKYENTLNTESDTFHCLLSDIQILVTGIDKTLGLAVEIYYRDKIQLIWLGLVLI
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEEEEEECCHHHHHHHHHHH
ILGTTHKLFIR
HHCCCCEEEEC
>Mature Secondary Structure
MVPSSCISMLTTIHYYLGTILLFLSLFSSLVRKPGTLFFLNSIIFIILFHAHLSNNFLLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
SVYSSSHTNLPLYYKLVASWTTHEGSMILWNWSLSLYLFIFSRKYRNSQIYQAVITIQSY
HHHCCCCCCCCEEEEEEHHHCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IASIFLLFTIYSSNPFKLFILAPSEGAGLNPILQDTALMIHPPILYLGYVGTSICFSIAI
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHCCCCEEECHHHHHHHHHHHHHHHHHH
AVLLTGKSGKEEFKLLNFFLLLAFIFLTSGIALGGWWSYRELGWGGFWSWDPVENISLFP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHCCCCCCCCCCCCCCCHHHH
YLVILGAIHSSFLSIKKWKSKALSIGLSILGFVTATFGTFITRMGITDSLHTFNTNTESG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
IYLLIITSLLSLTSAVIFIAKFRTLSSTDVSSNSNTESRDYLMSAQSILCLGLFIVLLLT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFAPKFSQIFGYDSIYIMQSFYNTVSGEVAGTLAVCICLFIVLTSKERCTKFIVLTLAAI
HCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VLSLGNFVNILTAFLSISGMMTMLSLLTKHVKDLQQEDSIKGIFRTKKNAFFLTHFGFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHH
FLYAVAGFASNSLENKQYFQIGEQRIVKQHIIKLTDFDKINNDLFSGIRATFTINGRAKL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEEECCCEEC
EPELRFYKYENTLNTESDTFHCLLSDIQILVTGIDKTLGLAVEIYYRDKIQLIWLGLVLI
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEEEEEECCHHHHHHHHHHH
ILGTTHKLFIR
HHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]