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The map label for this gene is ubiG

Identifier: 88608347

GI number: 88608347

Start: 550420

End: 551112

Strand: Reverse

Name: ubiG

Synonym: NSE_0628

Alternate gene names: 88608347

Gene position: 551112-550420 (Counterclockwise)

Preceding gene: 88608629

Following gene: 88608340

Centisome position: 64.16

GC content: 37.37

Gene sequence:

>693_bases
ATGACGACTGTAAATAAAAAGGAAATAGAAAAGTTTGCCGCTCTTGCTGATGAGTGGCACATCGCGAATGGCAGTTTCGA
GATGCTTCACAAAATGAATAAAGTGCGAGTGCGATATATACTAGGCCACGAAGACATAGTAGCGAAAAAGATACTCGATA
TAGGCTGTGGGGGCGGAATTCTTTCTGAAAATCTAGCAAGCCTTGGAGGAATTGTGACAGCAATAGATCCATGTAGCAAG
AGCATAAGAGTTGCTGAGGATCATGGTCGAGGTGAAGTAAAATATTTTGCTACGTCATTAGAGGATTATGTGAAGCAAAA
TAATAATGATAAATTTGATGTTATATGTATCATGGAAGTAATAGAGCATATTGATAATCTCAAGGAGTTTATGCACCTTT
GTGCAGAAATTTTGCTCCCAGGAGGAAAAATCTTTTTTTCTACACTGAATAAAACCGTGAAATCCTTTTTACTCGGTATT
CTTACAGCGGAATATATCCTCAGACTTGTTCCAAAGCATACTCATTCCTGGAAAAAGTTTTTATGTCCTTCTGTATTGAA
CAAGTTTTTTGAATGTTCCGGCTTGGAAATAAGAGGTATCAAAGGGCTAACTTATAGTATTCTATCCGACTCTTGGAGAT
TAGGCAGTGATGTTTCAATGAACTATGTAGGTCTTGCGATGCACAAAAAATAA

Upstream 100 bases:

>100_bases
ATTTAGTTAGAGTGTTTGTTGACTTCTTTGAGTGGAACGCATGGGTTATCTTTATTTTTAAGCGTAAATGCCAATTTAAG
GAGGAAGAGGGACTCTACGA

Downstream 100 bases:

>100_bases
AGTATGATCCTATCACTCAGGTTATTGGGAATTTTCAAACTTCTAGAACTCCTGTATGTGTATTGCGTGGACGAAAGTTG
GGGTACGATTTGATTCTCTT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTTVNKKEIEKFAALADEWHIANGSFEMLHKMNKVRVRYILGHEDIVAKKILDIGCGGGILSENLASLGGIVTAIDPCSK
SIRVAEDHGRGEVKYFATSLEDYVKQNNNDKFDVICIMEVIEHIDNLKEFMHLCAEILLPGGKIFFSTLNKTVKSFLLGI
LTAEYILRLVPKHTHSWKKFLCPSVLNKFFECSGLEIRGIKGLTYSILSDSWRLGSDVSMNYVGLAMHKK

Sequences:

>Translated_230_residues
MTTVNKKEIEKFAALADEWHIANGSFEMLHKMNKVRVRYILGHEDIVAKKILDIGCGGGILSENLASLGGIVTAIDPCSK
SIRVAEDHGRGEVKYFATSLEDYVKQNNNDKFDVICIMEVIEHIDNLKEFMHLCAEILLPGGKIFFSTLNKTVKSFLLGI
LTAEYILRLVPKHTHSWKKFLCPSVLNKFFECSGLEIRGIKGLTYSILSDSWRLGSDVSMNYVGLAMHKK
>Mature_229_residues
TTVNKKEIEKFAALADEWHIANGSFEMLHKMNKVRVRYILGHEDIVAKKILDIGCGGGILSENLASLGGIVTAIDPCSKS
IRVAEDHGRGEVKYFATSLEDYVKQNNNDKFDVICIMEVIEHIDNLKEFMHLCAEILLPGGKIFFSTLNKTVKSFLLGIL
TAEYILRLVPKHTHSWKKFLCPSVLNKFFECSGLEIRGIKGLTYSILSDSWRLGSDVSMNYVGLAMHKK

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=247, Percent_Identity=35.6275303643725, Blast_Score=175, Evalue=3e-44,
Organism=Escherichia coli, GI1788564, Length=225, Percent_Identity=38.2222222222222, Blast_Score=172, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=30.9623430962343, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=232, Percent_Identity=29.3103448275862, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281365311, Length=239, Percent_Identity=31.3807531380753, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=32.5991189427313, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 25839; Mature: 25707

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVNKKEIEKFAALADEWHIANGSFEMLHKMNKVRVRYILGHEDIVAKKILDIGCGGGI
CCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCCH
LSENLASLGGIVTAIDPCSKSIRVAEDHGRGEVKYFATSLEDYVKQNNNDKFDVICIMEV
HHHHHHHHCCHHHEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEHIDNLKEFMHLCAEILLPGGKIFFSTLNKTVKSFLLGILTAEYILRLVPKHTHSWKKF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LCPSVLNKFFECSGLEIRGIKGLTYSILSDSWRLGSDVSMNYVGLAMHKK
HHHHHHHHHHHCCCCEEECCCCCHHHHHCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TTVNKKEIEKFAALADEWHIANGSFEMLHKMNKVRVRYILGHEDIVAKKILDIGCGGGI
CCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCCH
LSENLASLGGIVTAIDPCSKSIRVAEDHGRGEVKYFATSLEDYVKQNNNDKFDVICIMEV
HHHHHHHHCCHHHEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IEHIDNLKEFMHLCAEILLPGGKIFFSTLNKTVKSFLLGILTAEYILRLVPKHTHSWKKF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LCPSVLNKFFECSGLEIRGIKGLTYSILSDSWRLGSDVSMNYVGLAMHKK
HHHHHHHHHHHCCCCEEECCCCCHHHHHCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA