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The map label for this gene is cbbT [H]

Identifier: 88608303

GI number: 88608303

Start: 622578

End: 624836

Strand: Direct

Name: cbbT [H]

Synonym: NSE_0704

Alternate gene names: 88608303

Gene position: 622578-624836 (Clockwise)

Preceding gene: 88608849

Following gene: 88607973

Centisome position: 72.48

GC content: 42.5

Gene sequence:

>2259_bases
ATGAGGAGAATGTCTGCAGCAATACGCGTATTGACTATAGATGCAGTGAGCCGTGCAAATTCTGGGCATCCTGGGATGCC
TTTGGGAATGGCAGATGTCGCAACTGTCCTATTTGCAAAGTTCCTCAAGTTTTGTCCTAACCACCCTGACTGGCCTGATA
GAGACCGTTTTGTATTGTCAGCGGGGCATGGCTCGATGCTGTTATATTCCCTATTGTACCTAACCGGTTATCCAGACTAT
ACGATTGAAGAACTCAAAAATTTCAGGCAGTTGCACTCGAAAACTCCTGGACACCCTGAGTACGGGATTGCAAAAGGGAT
AGAGAATACGTCTGGACCTCTTGGACAGGGTCTTGCAACGGGCATAGGAATGGCACTGGCGGAAGCAACATTAAACAGCC
GCTTCGGGAACATCATAGACCACTATACCTATATCATTGCTGGAGATGGATGTCTTATGGAGGGAATCAGCCACGAAGCA
GCATCTTTTGCTGGCCACATGAAACTCCGTAAGATAATACTTTTTTTTGATGACAACGGAATTTCAATCGACGGGAGCAC
ATCATTATGCTTATCAGATAATAATCTAAAACGTTTTGAAAGTTATGGATGGGATGTACAACAAATAGATGGCCACGACT
TTGCTGCAATAGAGAATGCAATAGCAAATGCCCGATCATCTGATAGGCCATCTCTGATTGCGGCAAAAACAGTGATAGGC
AAATCCATGCCAAAAGAAGGTACCAGTAAGACCCACAGTGGTGGCCTAACTCGAGAAGAAGTAATCGCATTTAGGAAAAG
GTTGGAATACCCATTAGAAGAATTTTCTATCCCCGAAGACGTCCTACGGAAGTGGCGCTCCTTGGGCAGTCTAGAAAGAT
ATAAGGAATGGCAACTCGCTTACAATAATCTTCCTGGGGAAGTTTCATTAGCTTTGGGAAGAACAGGAGCCGATCATAAC
ACTGATTTTCTTTTGAGCAGTAGCAAAGCCTCAACCAAAACACACAGTACTCCTACAAATGAAGAAGATTATATTCCTGC
ATCAGGAACACCTTATTTAGAGGGTATGGGCAATTCGAATGGACAACCTCAAAAACAGAACAATGTAAGTGGTGTGTGTA
ATAGTCCTGAACTACTGATACCCAGAGATAAACAAGAATTGTGTCATACTACAACTTCAGACAGCAATATTGGTAAGCTC
AACTCAGAAAACTCAATGCAAGATTTATGCATTGAACCCCAAAAATATCATCCACTAAAGTACACAGAGATATTCAATGA
ACTGAGGAATCACACTCAAGACGTTTCCTCTGAAGCAACAAGGCAGTCTTCCGGAAGAGTAGTAAAATTTCTCACAAGCA
AAATACCTGAAATGCTTGGGGGCTCCTGCGATCTTACTGGCTCCAATAACGTGGTCCCAGAACCATTTAAACCAATAAGT
GCCAGTAATTATAATGGCAATTACATACACTACGGTGTCAGAGAACATTTCATGGGAGCATGTATGAATGGTATGGCTTT
ACACGGAAACCTTGTTCCATATGGCGGAACTTTCCTTATCTTCTCGGACTATATGAGACCTTCTATCAGGATGTCTGCGT
TGATGGGTCTACAAACCATATATGTGATGACACACGATTCAATAGGTGTTGGTGAAGACGGACCGACTCATCAACCGGTT
GAACAGCTAGATAGTTTAAATCTTATTCCAAATTTGTATGTTTTTAGGCCATGCGACCATATAGAGGTAGCAGAATCCTG
GCAAGCTGCTTTGAGCATTACAAATGCACCGTCAGTAATAGTTTTGTCTCGGCAGAAGGTAAATTACTTGCAAAGGGAAT
TCCCCAAAGAAAACATGTGCTGTAAAGGCGCGTACCTGATAAAGAAAGCATCTAAAAAAGCAAAAGTTTCCCTTTTGGCA
AGCGGTTCCGAAGTTAGCATCTGCGCTGAAGTTCAAAGTGCATTGGAAAAATTGGGCTATCCAACAGATCTGGTATCTGT
GCCCTGCATTTCCATCCTCAAAAGAAACTCCACTAACCAAAATAGGAAACAACTAATTGAACCTGAAAGCATACCATTTG
TTGTCGAAGCGAGCTCGGGTTTAATGATTAGCTCCATGTTTGGTGTGGATTCAGAATCACTTTTCAATATCACGGAGTTT
GGTATATCTGCACCGTATGATAAGGTGTATAATCACTTTGGTTTGACTGTTGCAGCTGTATTAGAGCGTTGCCTGGATAA
GCTGTCGAAGTCCGAATGA

Upstream 100 bases:

>100_bases
TGAAATGCATATACCTGAATATTATCCAAGTATTAAAACTAAGGACTCAGAGATTAGCATGTGCTACAATTGGTTTTTCT
CGTGACTAGCTCAAAGGATA

Downstream 100 bases:

>100_bases
CAGATAGTGTATTTGCATTCTTATCTGCATAGAACAGACCCATTGAGGTCGGATTGGTTTGTGCAGCTTCGCGGTTAATT
GGATAGTAGCTATCTCATCC

Product: transketolase, insertion

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MRRMSAAIRVLTIDAVSRANSGHPGMPLGMADVATVLFAKFLKFCPNHPDWPDRDRFVLSAGHGSMLLYSLLYLTGYPDY
TIEELKNFRQLHSKTPGHPEYGIAKGIENTSGPLGQGLATGIGMALAEATLNSRFGNIIDHYTYIIAGDGCLMEGISHEA
ASFAGHMKLRKIILFFDDNGISIDGSTSLCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANARSSDRPSLIAAKTVIG
KSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSIPEDVLRKWRSLGSLERYKEWQLAYNNLPGEVSLALGRTGADHN
TDFLLSSSKASTKTHSTPTNEEDYIPASGTPYLEGMGNSNGQPQKQNNVSGVCNSPELLIPRDKQELCHTTTSDSNIGKL
NSENSMQDLCIEPQKYHPLKYTEIFNELRNHTQDVSSEATRQSSGRVVKFLTSKIPEMLGGSCDLTGSNNVVPEPFKPIS
ASNYNGNYIHYGVREHFMGACMNGMALHGNLVPYGGTFLIFSDYMRPSIRMSALMGLQTIYVMTHDSIGVGEDGPTHQPV
EQLDSLNLIPNLYVFRPCDHIEVAESWQAALSITNAPSVIVLSRQKVNYLQREFPKENMCCKGAYLIKKASKKAKVSLLA
SGSEVSICAEVQSALEKLGYPTDLVSVPCISILKRNSTNQNRKQLIEPESIPFVVEASSGLMISSMFGVDSESLFNITEF
GISAPYDKVYNHFGLTVAAVLERCLDKLSKSE

Sequences:

>Translated_752_residues
MRRMSAAIRVLTIDAVSRANSGHPGMPLGMADVATVLFAKFLKFCPNHPDWPDRDRFVLSAGHGSMLLYSLLYLTGYPDY
TIEELKNFRQLHSKTPGHPEYGIAKGIENTSGPLGQGLATGIGMALAEATLNSRFGNIIDHYTYIIAGDGCLMEGISHEA
ASFAGHMKLRKIILFFDDNGISIDGSTSLCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANARSSDRPSLIAAKTVIG
KSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSIPEDVLRKWRSLGSLERYKEWQLAYNNLPGEVSLALGRTGADHN
TDFLLSSSKASTKTHSTPTNEEDYIPASGTPYLEGMGNSNGQPQKQNNVSGVCNSPELLIPRDKQELCHTTTSDSNIGKL
NSENSMQDLCIEPQKYHPLKYTEIFNELRNHTQDVSSEATRQSSGRVVKFLTSKIPEMLGGSCDLTGSNNVVPEPFKPIS
ASNYNGNYIHYGVREHFMGACMNGMALHGNLVPYGGTFLIFSDYMRPSIRMSALMGLQTIYVMTHDSIGVGEDGPTHQPV
EQLDSLNLIPNLYVFRPCDHIEVAESWQAALSITNAPSVIVLSRQKVNYLQREFPKENMCCKGAYLIKKASKKAKVSLLA
SGSEVSICAEVQSALEKLGYPTDLVSVPCISILKRNSTNQNRKQLIEPESIPFVVEASSGLMISSMFGVDSESLFNITEF
GISAPYDKVYNHFGLTVAAVLERCLDKLSKSE
>Mature_752_residues
MRRMSAAIRVLTIDAVSRANSGHPGMPLGMADVATVLFAKFLKFCPNHPDWPDRDRFVLSAGHGSMLLYSLLYLTGYPDY
TIEELKNFRQLHSKTPGHPEYGIAKGIENTSGPLGQGLATGIGMALAEATLNSRFGNIIDHYTYIIAGDGCLMEGISHEA
ASFAGHMKLRKIILFFDDNGISIDGSTSLCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANARSSDRPSLIAAKTVIG
KSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSIPEDVLRKWRSLGSLERYKEWQLAYNNLPGEVSLALGRTGADHN
TDFLLSSSKASTKTHSTPTNEEDYIPASGTPYLEGMGNSNGQPQKQNNVSGVCNSPELLIPRDKQELCHTTTSDSNIGKL
NSENSMQDLCIEPQKYHPLKYTEIFNELRNHTQDVSSEATRQSSGRVVKFLTSKIPEMLGGSCDLTGSNNVVPEPFKPIS
ASNYNGNYIHYGVREHFMGACMNGMALHGNLVPYGGTFLIFSDYMRPSIRMSALMGLQTIYVMTHDSIGVGEDGPTHQPV
EQLDSLNLIPNLYVFRPCDHIEVAESWQAALSITNAPSVIVLSRQKVNYLQREFPKENMCCKGAYLIKKASKKAKVSLLA
SGSEVSICAEVQSALEKLGYPTDLVSVPCISILKRNSTNQNRKQLIEPESIPFVVEASSGLMISSMFGVDSESLFNITEF
GISAPYDKVYNHFGLTVAAVLERCLDKLSKSE

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=276, Percent_Identity=30.4347826086957, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI205277463, Length=237, Percent_Identity=32.0675105485232, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI4507521, Length=237, Percent_Identity=32.0675105485232, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=354, Percent_Identity=48.3050847457627, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1788808, Length=302, Percent_Identity=53.6423841059603, Blast_Score=323, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17539652, Length=241, Percent_Identity=31.5352697095436, Blast_Score=102, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325331, Length=284, Percent_Identity=47.5352112676056, Blast_Score=270, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6319593, Length=289, Percent_Identity=45.6747404844291, Blast_Score=260, Evalue=5e-70,
Organism=Drosophila melanogaster, GI45551847, Length=246, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45550715, Length=246, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666278, Length=262, Percent_Identity=31.2977099236641, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645119, Length=212, Percent_Identity=34.9056603773585, Blast_Score=116, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 82725; Mature: 82725

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMSAAIRVLTIDAVSRANSGHPGMPLGMADVATVLFAKFLKFCPNHPDWPDRDRFVLS
CCCHHHEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
AGHGSMLLYSLLYLTGYPDYTIEELKNFRQLHSKTPGHPEYGIAKGIENTSGPLGQGLAT
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHH
GIGMALAEATLNSRFGNIIDHYTYIIAGDGCLMEGISHEAASFAGHMKLRKIILFFDDNG
HHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHHEEEEEEEEECCCC
ISIDGSTSLCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANARSSDRPSLIAAKTVIG
EEECCCCEEEECCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEHHHHHH
KSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSIPEDVLRKWRSLGSLERYKEWQLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
YNNLPGEVSLALGRTGADHNTDFLLSSSKASTKTHSTPTNEEDYIPASGTPYLEGMGNSN
HCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQPQKQNNVSGVCNSPELLIPRDKQELCHTTTSDSNIGKLNSENSMQDLCIEPQKYHPLK
CCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCH
YTEIFNELRNHTQDVSSEATRQSSGRVVKFLTSKIPEMLGGSCDLTGSNNVVPEPFKPIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC
ASNYNGNYIHYGVREHFMGACMNGMALHGNLVPYGGTFLIFSDYMRPSIRMSALMGLQTI
CCCCCCCEEEECHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHEEE
YVMTHDSIGVGEDGPTHQPVEQLDSLNLIPNLYVFRPCDHIEVAESWQAALSITNAPSVI
EEEEECCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCEE
VLSRQKVNYLQREFPKENMCCKGAYLIKKASKKAKVSLLASGSEVSICAEVQSALEKLGY
EECHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHCCC
PTDLVSVPCISILKRNSTNQNRKQLIEPESIPFVVEASSGLMISSMFGVDSESLFNITEF
CHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEECCCCEEEEHECCCCCHHHHHHHHH
GISAPYDKVYNHFGLTVAAVLERCLDKLSKSE
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRMSAAIRVLTIDAVSRANSGHPGMPLGMADVATVLFAKFLKFCPNHPDWPDRDRFVLS
CCCHHHEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
AGHGSMLLYSLLYLTGYPDYTIEELKNFRQLHSKTPGHPEYGIAKGIENTSGPLGQGLAT
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHH
GIGMALAEATLNSRFGNIIDHYTYIIAGDGCLMEGISHEAASFAGHMKLRKIILFFDDNG
HHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHHEEEEEEEEECCCC
ISIDGSTSLCLSDNNLKRFESYGWDVQQIDGHDFAAIENAIANARSSDRPSLIAAKTVIG
EEECCCCEEEECCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEHHHHHH
KSMPKEGTSKTHSGGLTREEVIAFRKRLEYPLEEFSIPEDVLRKWRSLGSLERYKEWQLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
YNNLPGEVSLALGRTGADHNTDFLLSSSKASTKTHSTPTNEEDYIPASGTPYLEGMGNSN
HCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQPQKQNNVSGVCNSPELLIPRDKQELCHTTTSDSNIGKLNSENSMQDLCIEPQKYHPLK
CCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCH
YTEIFNELRNHTQDVSSEATRQSSGRVVKFLTSKIPEMLGGSCDLTGSNNVVPEPFKPIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC
ASNYNGNYIHYGVREHFMGACMNGMALHGNLVPYGGTFLIFSDYMRPSIRMSALMGLQTI
CCCCCCCEEEECHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHEEE
YVMTHDSIGVGEDGPTHQPVEQLDSLNLIPNLYVFRPCDHIEVAESWQAALSITNAPSVI
EEEEECCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCEE
VLSRQKVNYLQREFPKENMCCKGAYLIKKASKKAKVSLLASGSEVSICAEVQSALEKLGY
EECHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHCCC
PTDLVSVPCISILKRNSTNQNRKQLIEPESIPFVVEASSGLMISSMFGVDSESLFNITEF
CHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEECCCCEEEEHECCCCCHHHHHHHHH
GISAPYDKVYNHFGLTVAAVLERCLDKLSKSE
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA