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The map label for this gene is ycfH [C]

Identifier: 88608135

GI number: 88608135

Start: 293164

End: 293970

Strand: Reverse

Name: ycfH [C]

Synonym: NSE_0357

Alternate gene names: 88608135

Gene position: 293970-293164 (Counterclockwise)

Preceding gene: 88608785

Following gene: 88608415

Centisome position: 34.22

GC content: 39.28

Gene sequence:

>807_bases
TTGAATCCATTTCCTGAATCAGATTGCCAAATGATTTTTGATTCGCATTGTCATCTTCTTTTCTACGGAAAAGAAGCAAT
AAAGGATATTGTGGAAGAAGCAAAAAGAAATGGTGTAGGAGTCTTACATAATATCGCGACCAAGTTAAGCGAAGTTGAAG
ATTTGCTTTCAATTTCCGAGCAATTCTCCAATGTCTACTGCTCTGTAGGTGTACACCCAAATCACGTCGAGCACTGTGAA
TCCCTAAAAGAAACACTAATATCATTGGCAACACATGAAAAGGTGATAAGCATAGGCGAAACAGGATTAGATTACTATTA
CGACTACACTACTAAGAAAGTTCAACAGGAATCGTTTAGAGAGCATATACGAGCGGCCTTGGAATCAAACTTACCACTCG
TAGTACATTCGAGAAATGCCGAAACTGATACAGTACGTATACTGGAAACTGAGTTGAGCGACAGTAGAACACCAGTGATT
CTCCATAGCTTCGCTTCATCTAGAGAGCTTTTCGAAGCAGCGATAAGAAATGCTTGGTATGTTTCATTTTCTGGGATCGT
AACATTTAAAAATGCCACAGAAGTACAAAAAATAGCCGTTGAGGTACCACTGGATAGAATGCTTATAGAAACCGACGCGC
CCTATCTTTCTCCTGTCCCATTTAGAGGTAAAACGAACTATCCCTCGTATATTGTGCACATACTAAAACATATAAGCAAA
CTTAGACGCATCGAAAACGTGGAATTGTCGACAAAACTAATGGAGAATTTTCTTAGGGTGTTTCCAAAGGTCATTCGACC
AACATGA

Upstream 100 bases:

>100_bases
ATTCACGACCCGGTTTAGTGTGTGTTTTGTGTGGATAGTTTTGCCTACGTGTTTTCTCTTGCCCGCGTTTTTACTCTCCC
TATCGTGATGCCTGGAGTTT

Downstream 100 bases:

>100_bases
CAGTATCTATACTGACATAAACCACAAAAAGACGAGTTCTCTGTTGAATTTGCAAGACCTCAAGCTTATCACTCAGACTC
AGCAGCCATTCGCATATGCC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNPFPESDCQMIFDSHCHLLFYGKEAIKDIVEEAKRNGVGVLHNIATKLSEVEDLLSISEQFSNVYCSVGVHPNHVEHCE
SLKETLISLATHEKVISIGETGLDYYYDYTTKKVQQESFREHIRAALESNLPLVVHSRNAETDTVRILETELSDSRTPVI
LHSFASSRELFEAAIRNAWYVSFSGIVTFKNATEVQKIAVEVPLDRMLIETDAPYLSPVPFRGKTNYPSYIVHILKHISK
LRRIENVELSTKLMENFLRVFPKVIRPT

Sequences:

>Translated_268_residues
MNPFPESDCQMIFDSHCHLLFYGKEAIKDIVEEAKRNGVGVLHNIATKLSEVEDLLSISEQFSNVYCSVGVHPNHVEHCE
SLKETLISLATHEKVISIGETGLDYYYDYTTKKVQQESFREHIRAALESNLPLVVHSRNAETDTVRILETELSDSRTPVI
LHSFASSRELFEAAIRNAWYVSFSGIVTFKNATEVQKIAVEVPLDRMLIETDAPYLSPVPFRGKTNYPSYIVHILKHISK
LRRIENVELSTKLMENFLRVFPKVIRPT
>Mature_268_residues
MNPFPESDCQMIFDSHCHLLFYGKEAIKDIVEEAKRNGVGVLHNIATKLSEVEDLLSISEQFSNVYCSVGVHPNHVEHCE
SLKETLISLATHEKVISIGETGLDYYYDYTTKKVQQESFREHIRAALESNLPLVVHSRNAETDTVRILETELSDSRTPVI
LHSFASSRELFEAAIRNAWYVSFSGIVTFKNATEVQKIAVEVPLDRMLIETDAPYLSPVPFRGKTNYPSYIVHILKHISK
LRRIENVELSTKLMENFLRVFPKVIRPT

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=269, Percent_Identity=25.2788104089219, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=27.6119402985075, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=27.2388059701493, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=26.7399267399267, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI225903424, Length=207, Percent_Identity=28.9855072463768, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI225903439, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=27.3127753303965, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=26.6409266409266, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=39.453125, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI48994985, Length=239, Percent_Identity=30.1255230125523, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=27.5862068965517, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=199, Percent_Identity=27.6381909547739, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=26.4150943396226, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=253, Percent_Identity=27.6679841897233, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=213, Percent_Identity=26.7605633802817, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648690, Length=199, Percent_Identity=28.1407035175879, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330018, Length=203, Percent_Identity=29.5566502463054, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24586117, Length=203, Percent_Identity=29.5566502463054, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30608; Mature: 30608

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFPESDCQMIFDSHCHLLFYGKEAIKDIVEEAKRNGVGVLHNIATKLSEVEDLLSISE
CCCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QFSNVYCSVGVHPNHVEHCESLKETLISLATHEKVISIGETGLDYYYDYTTKKVQQESFR
HHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EHIRAALESNLPLVVHSRNAETDTVRILETELSDSRTPVILHSFASSRELFEAAIRNAWY
HHHHHHHHCCCCEEEECCCCCCHHHEEEEHHCCCCCCCEEEEHHHHHHHHHHHHHHHCEE
VSFSGIVTFKNATEVQKIAVEVPLDRMLIETDAPYLSPVPFRGKTNYPSYIVHILKHISK
EEEECEEEECCHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LRRIENVELSTKLMENFLRVFPKVIRPT
HHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPFPESDCQMIFDSHCHLLFYGKEAIKDIVEEAKRNGVGVLHNIATKLSEVEDLLSISE
CCCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QFSNVYCSVGVHPNHVEHCESLKETLISLATHEKVISIGETGLDYYYDYTTKKVQQESFR
HHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EHIRAALESNLPLVVHSRNAETDTVRILETELSDSRTPVILHSFASSRELFEAAIRNAWY
HHHHHHHHCCCCEEEECCCCCCHHHEEEEHHCCCCCCCEEEEHHHHHHHHHHHHHHHCEE
VSFSGIVTFKNATEVQKIAVEVPLDRMLIETDAPYLSPVPFRGKTNYPSYIVHILKHISK
EEEECEEEECCHHHHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LRRIENVELSTKLMENFLRVFPKVIRPT
HHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]