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The map label for this gene is clpX

Identifier: 88608107

GI number: 88608107

Start: 670013

End: 671215

Strand: Direct

Name: clpX

Synonym: NSE_0753

Alternate gene names: 88608107

Gene position: 670013-671215 (Clockwise)

Preceding gene: 88608072

Following gene: 88608834

Centisome position: 78.0

GC content: 40.98

Gene sequence:

>1203_bases
GTGGTAAACAAGAGTGATCTGGTTCCGAAGTGCTCTTTTTGTGGTGAGACGGAAGACAAAGTACGGAAACTTGTTGCGGG
TATGTCCGCATTTATCTGTGACAGATGCATAGCGTTATGCTCTAACGTACTCAGTGAAGAAATTACTCTTGAAGCAGTTT
CTGCAGAAAGATTCACTCCGAAGGACATAAAGAAATACTTTGATTCATTCATTACAGCTCAAGAGGACGCCAAGAAAATA
CTTTCTGTTGCGGTCTATAACCATTACAAATGCTTTGTGGGTAATAGGCTTAATTCGAAGGATGTTGAAATCACAAAATC
TAATATTCTTATCATCGGGCCTACTGGCTGCGGAAAAACACTTTTTGCAAAAACATTGGCACGCTTTTTGAATGTACCGT
TCGCAATTTGTGATGCTACAAGTATTACTGAGGCTGGCTATGTAGGAGACGATGTAGAAAACATCTTGAGGATGCTCCTA
CAATCTGCTGACTACAACGTTGAAGCAGCACAAAAAGGAATAGTGTACATCGACGAGATTGATAAGATTTCCAGAAAGTC
GGACAGTCCATCCATAACAAGAGACGTCTCTGGAGAAGGGGTTCAACAAGCCTTGCTCAAAATTATGGAAGGGACAATTG
CATCTGTTCCTCCTCAGGGAGGGCGCAAGCATCCAAACCAGGAAACCATACAAATCGATACGACTAACATATTATTCATC
TGTGGTGGTGCTTTCGTCGGGTTAGACAATATAATCGCAAACCGTCAAAGCATTAATACGATGGGATTTAAATCTGAACT
TCAAAGTAAAGAGGTTTCTCCAACAATACTGAAGAAAGTCGAACCTGAGGATCTGGTTAAATTTGGTATGATTCCTGAAT
TTGTTGGACGGTTGCCCGTAATAGGAGTGCTTGATGAACTAACGGAAGACAATTTGGTCGAAATACTGTCGGTACCAAAA
AATGCACTCGTAAAACAGTATGTATGCTTATTTGGAATGGATAATATACAACTCTCCTTTAGTGATGAAGCACTCAAGAC
AGTGGCTCGTGCAGCAATCAAAAGAAAGGTCGGTGCTAGAGGGCTAAGGGCAATTATGGAATCTGTACTACGTAATTACA
TGTTTGAACTCCCGAGTAACAAAGATGTTAAGACACTCATTATCACAGAGGATATAGTACGTGCAGAGATGGCGAACACT
TAG

Upstream 100 bases:

>100_bases
AAAATAGAAACGTTGCTCGAGAGAGATACCTTTTTGAGCCCGGAAGAAGCGAAAAAGGTTGGCATAATTGATGACATAAT
CACACAGAGGAAAGAGAATA

Downstream 100 bases:

>100_bases
TGCTGTTCCAGCCACTTAGACGCCATATGATCAATTGTAGAAATCTTTTTACGCTGGTAGACCATTTGTCTTTCAGGAAA
ATTTTTCGACAGTATAAAAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MVNKSDLVPKCSFCGETEDKVRKLVAGMSAFICDRCIALCSNVLSEEITLEAVSAERFTPKDIKKYFDSFITAQEDAKKI
LSVAVYNHYKCFVGNRLNSKDVEITKSNILIIGPTGCGKTLFAKTLARFLNVPFAICDATSITEAGYVGDDVENILRMLL
QSADYNVEAAQKGIVYIDEIDKISRKSDSPSITRDVSGEGVQQALLKIMEGTIASVPPQGGRKHPNQETIQIDTTNILFI
CGGAFVGLDNIIANRQSINTMGFKSELQSKEVSPTILKKVEPEDLVKFGMIPEFVGRLPVIGVLDELTEDNLVEILSVPK
NALVKQYVCLFGMDNIQLSFSDEALKTVARAAIKRKVGARGLRAIMESVLRNYMFELPSNKDVKTLIITEDIVRAEMANT

Sequences:

>Translated_400_residues
MVNKSDLVPKCSFCGETEDKVRKLVAGMSAFICDRCIALCSNVLSEEITLEAVSAERFTPKDIKKYFDSFITAQEDAKKI
LSVAVYNHYKCFVGNRLNSKDVEITKSNILIIGPTGCGKTLFAKTLARFLNVPFAICDATSITEAGYVGDDVENILRMLL
QSADYNVEAAQKGIVYIDEIDKISRKSDSPSITRDVSGEGVQQALLKIMEGTIASVPPQGGRKHPNQETIQIDTTNILFI
CGGAFVGLDNIIANRQSINTMGFKSELQSKEVSPTILKKVEPEDLVKFGMIPEFVGRLPVIGVLDELTEDNLVEILSVPK
NALVKQYVCLFGMDNIQLSFSDEALKTVARAAIKRKVGARGLRAIMESVLRNYMFELPSNKDVKTLIITEDIVRAEMANT
>Mature_400_residues
MVNKSDLVPKCSFCGETEDKVRKLVAGMSAFICDRCIALCSNVLSEEITLEAVSAERFTPKDIKKYFDSFITAQEDAKKI
LSVAVYNHYKCFVGNRLNSKDVEITKSNILIIGPTGCGKTLFAKTLARFLNVPFAICDATSITEAGYVGDDVENILRMLL
QSADYNVEAAQKGIVYIDEIDKISRKSDSPSITRDVSGEGVQQALLKIMEGTIASVPPQGGRKHPNQETIQIDTTNILFI
CGGAFVGLDNIIANRQSINTMGFKSELQSKEVSPTILKKVEPEDLVKFGMIPEFVGRLPVIGVLDELTEDNLVEILSVPK
NALVKQYVCLFGMDNIQLSFSDEALKTVARAAIKRKVGARGLRAIMESVLRNYMFELPSNKDVKTLIITEDIVRAEMANT

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=322, Percent_Identity=49.0683229813665, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=393, Percent_Identity=57.2519083969466, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1790366, Length=107, Percent_Identity=41.1214953271028, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=43.5897435897436, Blast_Score=264, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=43.5897435897436, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=402, Percent_Identity=36.81592039801, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI71988660, Length=246, Percent_Identity=38.6178861788618, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319704, Length=416, Percent_Identity=39.1826923076923, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24648289, Length=316, Percent_Identity=48.4177215189873, Blast_Score=294, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24648291, Length=316, Percent_Identity=48.4177215189873, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_NEOSM (Q2GD18)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506628.1
- ProteinModelPortal:   Q2GD18
- STRING:   Q2GD18
- GeneID:   3931978
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0753
- TIGR:   NSE_0753
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q2GD18
- ProtClustDB:   PRK05342
- BioCyc:   NSEN222891:NSE_0753-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 44040; Mature: 44040

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKSDLVPKCSFCGETEDKVRKLVAGMSAFICDRCIALCSNVLSEEITLEAVSAERFTP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
KDIKKYFDSFITAQEDAKKILSVAVYNHYKCFVGNRLNSKDVEITKSNILIIGPTGCGKT
HHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEECCEEEEECCCCCHH
LFAKTLARFLNVPFAICDATSITEAGYVGDDVENILRMLLQSADYNVEAAQKGIVYIDEI
HHHHHHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEEEECH
DKISRKSDSPSITRDVSGEGVQQALLKIMEGTIASVPPQGGRKHPNQETIQIDTTNILFI
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEECCEEEEE
CGGAFVGLDNIIANRQSINTMGFKSELQSKEVSPTILKKVEPEDLVKFGMIPEFVGRLPV
ECCHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCHHHHCCCCH
IGVLDELTEDNLVEILSVPKNALVKQYVCLFGMDNIQLSFSDEALKTVARAAIKRKVGAR
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
GLRAIMESVLRNYMFELPSNKDVKTLIITEDIVRAEMANT
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCC
>Mature Secondary Structure
MVNKSDLVPKCSFCGETEDKVRKLVAGMSAFICDRCIALCSNVLSEEITLEAVSAERFTP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
KDIKKYFDSFITAQEDAKKILSVAVYNHYKCFVGNRLNSKDVEITKSNILIIGPTGCGKT
HHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEECCEEEEECCCCCHH
LFAKTLARFLNVPFAICDATSITEAGYVGDDVENILRMLLQSADYNVEAAQKGIVYIDEI
HHHHHHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEEEECH
DKISRKSDSPSITRDVSGEGVQQALLKIMEGTIASVPPQGGRKHPNQETIQIDTTNILFI
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEECCEEEEE
CGGAFVGLDNIIANRQSINTMGFKSELQSKEVSPTILKKVEPEDLVKFGMIPEFVGRLPV
ECCHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCHHHHCCCCH
IGVLDELTEDNLVEILSVPKNALVKQYVCLFGMDNIQLSFSDEALKTVARAAIKRKVGAR
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
GLRAIMESVLRNYMFELPSNKDVKTLIITEDIVRAEMANT
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA