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The map label for this gene is ribB

Identifier: 88608102

GI number: 88608102

Start: 569117

End: 569749

Strand: Reverse

Name: ribB

Synonym: NSE_0649

Alternate gene names: 88608102

Gene position: 569749-569117 (Counterclockwise)

Preceding gene: 88608366

Following gene: 88608005

Centisome position: 66.33

GC content: 41.86

Gene sequence:

>633_bases
ATGTTTTCCACTGTAGAAGAGGTAATACACCAGCTTAAAGAAAGGAATAAGCCTTTTGTTCTTGTTGACTCCAGTGATAG
AGAGAATGAGGGTGATATAGTGGTACCAGTTCAAATACTGACAAGTGAGATCATGAATTTTGTAGTCACACATTGTCGTG
GTCTTCCATGTGTCTGTGTAACTAAAAGTTTGTGTGAAAAGCTCGGCTTAGATCTTATCAAGCGGTCTGATTCGTGTGAG
TCTTCCAATGTTGCTAGATTTGTCACTACCATAGAGGCAAAGGAAGGTGTGAGTACGGGAATATCTGTTCGTGACCGTGT
GCGCACTATGCGCCTGTTGGCGAATGATAATGTCGATAAGGATAGCTTTGTTTCACCTGGACATGTTTTTCCGTTAATGA
TAGAGGAAGGAGGGTTGATGGTGCGCTCTGGGCACACTGAGGGTGCTGCAACTTTTGCTCGTTTAGCTGGTTTTAAATCA
GAGTCCATGCTGTGCGAGATACTTGATGAGGCTGGTGATGCAGCTAGATTACCCTATTTAACGGACTTCGCTAGGAAATA
TGATCTTTGCCTTACTAGCATAGATCTTTTAATTACTTATCTGAAAGAGAAAGGTACTAGCATTCTCTTTTAA

Upstream 100 bases:

>100_bases
GCGCTACTTTTGATCGTTATTTTTGTGTTGTGTCAGGCCTAGACATTGGATTTTTATAGGAACATGCTTTACTCTATACA
TTGCCTAACTTGCTATATAA

Downstream 100 bases:

>100_bases
CGAGTCAGACGATATGGATTCTTTATGAAACTTCTTAGGTGGCGTCTTTCTCTTGTTATGGGGTTTCTTTGTTTGTCTGT
GATCGCTTGCTTTTCTAGTA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MFSTVEEVIHQLKERNKPFVLVDSSDRENEGDIVVPVQILTSEIMNFVVTHCRGLPCVCVTKSLCEKLGLDLIKRSDSCE
SSNVARFVTTIEAKEGVSTGISVRDRVRTMRLLANDNVDKDSFVSPGHVFPLMIEEGGLMVRSGHTEGAATFARLAGFKS
ESMLCEILDEAGDAARLPYLTDFARKYDLCLTSIDLLITYLKEKGTSILF

Sequences:

>Translated_210_residues
MFSTVEEVIHQLKERNKPFVLVDSSDRENEGDIVVPVQILTSEIMNFVVTHCRGLPCVCVTKSLCEKLGLDLIKRSDSCE
SSNVARFVTTIEAKEGVSTGISVRDRVRTMRLLANDNVDKDSFVSPGHVFPLMIEEGGLMVRSGHTEGAATFARLAGFKS
ESMLCEILDEAGDAARLPYLTDFARKYDLCLTSIDLLITYLKEKGTSILF
>Mature_210_residues
MFSTVEEVIHQLKERNKPFVLVDSSDRENEGDIVVPVQILTSEIMNFVVTHCRGLPCVCVTKSLCEKLGLDLIKRSDSCE
SSNVARFVTTIEAKEGVSTGISVRDRVRTMRLLANDNVDKDSFVSPGHVFPLMIEEGGLMVRSGHTEGAATFARLAGFKS
ESMLCEILDEAGDAARLPYLTDFARKYDLCLTSIDLLITYLKEKGTSILF

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=37.1859296482412, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320695, Length=209, Percent_Identity=33.9712918660287, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23257; Mature: 23257

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTVEEVIHQLKERNKPFVLVDSSDRENEGDIVVPVQILTSEIMNFVVTHCRGLPCVCV
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHH
TKSLCEKLGLDLIKRSDSCESSNVARFVTTIEAKEGVSTGISVRDRVRTMRLLANDNVDK
HHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DSFVSPGHVFPLMIEEGGLMVRSGHTEGAATFARLAGFKSESMLCEILDEAGDAARLPYL
CCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHH
TDFARKYDLCLTSIDLLITYLKEKGTSILF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFSTVEEVIHQLKERNKPFVLVDSSDRENEGDIVVPVQILTSEIMNFVVTHCRGLPCVCV
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHH
TKSLCEKLGLDLIKRSDSCESSNVARFVTTIEAKEGVSTGISVRDRVRTMRLLANDNVDK
HHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DSFVSPGHVFPLMIEEGGLMVRSGHTEGAATFARLAGFKSESMLCEILDEAGDAARLPYL
CCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHH
TDFARKYDLCLTSIDLLITYLKEKGTSILF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]