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The map label for this gene is virB9-1

Identifier: 88608055

GI number: 88608055

Start: 178418

End: 179218

Strand: Reverse

Name: virB9-1

Synonym: NSE_0210

Alternate gene names: 88608055

Gene position: 179218-178418 (Counterclockwise)

Preceding gene: 88607971

Following gene: 88608821

Centisome position: 20.86

GC content: 42.82

Gene sequence:

>801_bases
ATGAAGAGATCCAATAATTTTGCCATCTTACTCACACTACAGTTCATGCTCTGTTTACCCGTGTTTGCTGACCAAAAGGC
TCACTCGTTGGCTTCTACTCCGCATATAAAAGAGATGGTTTACAATCCAAATGGTATTCATACGTACACTGGGTTTTTCG
GCTACCAGTCCAGCATAGTTTTCGAGGATGGAGAGGTGATAAGTACTATTTCTATGGGCGACTCCACTGGTTGGCAGCTT
GATACTCAGGGCAATAGACTCTTCCTTAAACCCGTCGAAGACAACGCGACAACAAACGTCACGATTCTTACAAGCAAGCG
GGTTTATCATTTTGTCTTCAACGCCAAGGAAGCTCGGGATGTGTACGATCCAGAGCTAGCATACGAAGTACGTTTCCGAT
ATCCTTCGCATGCTGTCAGTATACAAAGCGCTGGTATTACAGGCGTGCAGAACGAAACAGTGGGAAGTACTGAGCTTGAC
ATTGGCAAAAAAGCATATCTGAATTTTGAGTATAAGCTTTCTGGGTATGATGCAATAAAACCACTCAAAGTTTTTGATGA
TGGACGCTTTACTTATATGCAGTTCCCAAGTGTAAATGCAAACCTGCCGGCTGTTTTCCGAGTTGATTCGCAAGGATATG
AGGCTTTGGTGAATTACCATATTTCGGGCAAATATCTGGTAGTGCAAGAGGTTGCACCATTGTTCACATTGCGTCATGGA
AATGATCACGTGTGTGTTTTCAACATGAAAGCTGCCATTAAGAAAAGAAAGGGCAGTACTAAGGTTTTTACAAATGGGTA
A

Upstream 100 bases:

>100_bases
AATAAGAACCGAGAAAAGACGGTAAAGGTTGCTTTCAGGACGACAGATGTTATTTTAGCGCATAGAGACGTCGCACCATT
AGAGTTAATAGTAAGCGGTT

Downstream 100 bases:

>100_bases
GAACCGGAACACTTCTGATATGTTGGAATCAGTCGTTGTACATGGCGTAGCAGATTCTATTACTTTATTTGAAGTAAAGC
ACGCCCTGCATGAACGTGGG

Product: type IV secretion system protein VirB9

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKRSNNFAILLTLQFMLCLPVFADQKAHSLASTPHIKEMVYNPNGIHTYTGFFGYQSSIVFEDGEVISTISMGDSTGWQL
DTQGNRLFLKPVEDNATTNVTILTSKRVYHFVFNAKEARDVYDPELAYEVRFRYPSHAVSIQSAGITGVQNETVGSTELD
IGKKAYLNFEYKLSGYDAIKPLKVFDDGRFTYMQFPSVNANLPAVFRVDSQGYEALVNYHISGKYLVVQEVAPLFTLRHG
NDHVCVFNMKAAIKKRKGSTKVFTNG

Sequences:

>Translated_266_residues
MKRSNNFAILLTLQFMLCLPVFADQKAHSLASTPHIKEMVYNPNGIHTYTGFFGYQSSIVFEDGEVISTISMGDSTGWQL
DTQGNRLFLKPVEDNATTNVTILTSKRVYHFVFNAKEARDVYDPELAYEVRFRYPSHAVSIQSAGITGVQNETVGSTELD
IGKKAYLNFEYKLSGYDAIKPLKVFDDGRFTYMQFPSVNANLPAVFRVDSQGYEALVNYHISGKYLVVQEVAPLFTLRHG
NDHVCVFNMKAAIKKRKGSTKVFTNG
>Mature_266_residues
MKRSNNFAILLTLQFMLCLPVFADQKAHSLASTPHIKEMVYNPNGIHTYTGFFGYQSSIVFEDGEVISTISMGDSTGWQL
DTQGNRLFLKPVEDNATTNVTILTSKRVYHFVFNAKEARDVYDPELAYEVRFRYPSHAVSIQSAGITGVQNETVGSTELD
IGKKAYLNFEYKLSGYDAIKPLKVFDDGRFTYMQFPSVNANLPAVFRVDSQGYEALVNYHISGKYLVVQEVAPLFTLRHG
NDHVCVFNMKAAIKKRKGSTKVFTNG

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG3504

COG function: function code U; Type IV secretory pathway, VirB9 components

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbG/virB9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010258
- InterPro:   IPR014148 [H]

Pfam domain/function: PF03524 CagX [H]

EC number: NA

Molecular weight: Translated: 29900; Mature: 29900

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSNNFAILLTLQFMLCLPVFADQKAHSLASTPHIKEMVYNPNGIHTYTGFFGYQSSIV
CCCCCCEEEEEEEHHHHHHHHHCCCCHHHHCCCCCHHHEEECCCCCEEEEEEECCCCEEE
FEDGEVISTISMGDSTGWQLDTQGNRLFLKPVEDNATTNVTILTSKRVYHFVFNAKEARD
EECCCEEEEEECCCCCCEEEECCCCEEEEEECCCCCCEEEEEEECCEEEEEEECCCHHCC
VYDPELAYEVRFRYPSHAVSIQSAGITGVQNETVGSTELDIGKKAYLNFEYKLSGYDAIK
CCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCC
PLKVFDDGRFTYMQFPSVNANLPAVFRVDSQGYEALVNYHISGKYLVVQEVAPLFTLRHG
CEEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEEEECCCEEEEECC
NDHVCVFNMKAAIKKRKGSTKVFTNG
CCEEEEEEHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MKRSNNFAILLTLQFMLCLPVFADQKAHSLASTPHIKEMVYNPNGIHTYTGFFGYQSSIV
CCCCCCEEEEEEEHHHHHHHHHCCCCHHHHCCCCCHHHEEECCCCCEEEEEEECCCCEEE
FEDGEVISTISMGDSTGWQLDTQGNRLFLKPVEDNATTNVTILTSKRVYHFVFNAKEARD
EECCCEEEEEECCCCCCEEEECCCCEEEEEECCCCCCEEEEEEECCEEEEEEECCCHHCC
VYDPELAYEVRFRYPSHAVSIQSAGITGVQNETVGSTELDIGKKAYLNFEYKLSGYDAIK
CCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCC
PLKVFDDGRFTYMQFPSVNANLPAVFRVDSQGYEALVNYHISGKYLVVQEVAPLFTLRHG
CEEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEEEECCCEEEEECC
NDHVCVFNMKAAIKKRKGSTKVFTNG
CCEEEEEEHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA