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The map label for this gene is nuoG

Identifier: 88608010

GI number: 88608010

Start: 44209

End: 46248

Strand: Direct

Name: nuoG

Synonym: NSE_0053

Alternate gene names: 88608010

Gene position: 44209-46248 (Clockwise)

Preceding gene: 88608576

Following gene: 88608314

Centisome position: 5.15

GC content: 44.17

Gene sequence:

>2040_bases
ATGCCGAATGTTACTATCAACGGTAAGAAGCTTTTGGTTGAGTCTGGATGTACTGTCATCCAGGCCTGCCAAATGGCTGG
CGTTGAGGTGCCCAGATTTTGCTATCATGAGCGTCTTAAGATAGCTGGCAATTGTCGAATGTGTCTTGTTGAAGTTGAGG
GTGGTCCTCCGAAGCTGGCCGCTTCTTGTGCAACTCCGGTTGTTGATAACATGGTTGTGCATACCGACACGCCAAAAATA
AGGGCTGCGAGAGAGGGTGTCATGGAGTTTTTACTTGCCAACCACCCTTTGGACTGCCCTATATGCGACCAGGGTGGTGA
GTGTGATCTCCAAGATCAGGCAATACTTTATGGGAAAGGTGAAGGTCGGTTCTCTTACGCCAAAAGGTCCGTACAGAAAA
AAGATTTTGGACCCGTGATCTCAACCGAGATGAATCGCTGCATACACTGTACCCGTTGTATTCGTTTTCTATCCGATGTT
GCCGGTGTGGAAGAACTCGGGATGGTTAACAGGGGGGCTGATTCTGAGATAAGTACCTACATACAAAAATCTCTATCATC
GGAACTTTCTGGCAATATAATAGACCTATGTCCGGTTGGGGCTCTCACGTCGAAGCCATACGCTTTTACAGCTCGTCCGT
GGGAACTTACAAAAATCGAAAGTGTAGATGTTCTCGATGCAGTTGGCAGCAACATCAGGATTGATGTAAGAGGGCAAACG
GTGATGCGTATACTTCCGCGATTGAATGAAGAAATAAATGAGGAATGGCTCTCGGATAGGTCGCGCTTCTCCTATGACGG
TCTAAGGGTACAGAGGTTGGATAGGTGCTATGTGAGAGTGAATGGCAAGCTCCATGAGTCTACATGGAAAAAAGCAATAT
CCGAGATTGTTAAACAGATTGATCACGTAAATCGTGAAGAAATTGCTGCAGTTGCAGGAGATTTGGCCGATGTGGAGTCA
GTTTTCCTTCTAAAAAGGATGCTCAATAAGTTGGGGGTTTCTAAGACCGAATGCAGGCAAGACGGGGCGAGTTATATGGT
CTCGGAGCGCGATTTTTATACCTTTAATACCACTTTTGCTGGTATAGAAGAATCAGATTTTTGTTTTCTTGTTGGAGCGA
ATTTACGCGTAGATGCTCCACTAATAGCTGCAAGAATTAGAAAAAGGTGGTTGTCTGGTAATTATACAGTAGTAGGTTTG
GGAAGCGATGCAAAATATGCTTTTGATGTCTCAAGCATTGGTAATGATGCTGCCACGCTTGTTGAGATAGCATCTGGTAG
AAATCAGAAATTCCAGGAGTTGTTAGGTAGTTCCAGAAGGCCAATGATGATTGTTGGTCCCGATGTTCTAAGCCGCGCAG
ATGCGAATTATATAATCTCGTTGCTCCGAGCGATCGCTGAGAGGTTTGGATTTTTTCAAGAGAGTTTTAATGGCTTCTCA
GTGTTACAGCGTCACTCTGGAACTGTTGGTGCTCTGGATGTAGGCTTTTATCACCAGGATGGTTTAAAAGGTGTTCTCAA
TGGTGATACGAAGCTTGTTTACCTTTTAGGTGCTGATGATTGCGTTGAGAGCATACCTGAAGGTGCGTTTGTTGTGTATC
AAGGTCATCATGGTGATAAGGGTGCATCTCGGGCTAATGTCATACTTCCTGGTTGCTCTTACGTAGAAAAAGATGCAATT
TATGTTAATGCTGAGGGAAGAGCACAGCTTGCCTTTAGAGCTGTTTTTCCTCCTGGTGAAGCGAGGGATGATAGAGAGAT
TATAGCGGAACTTGCTCAAGCACTTGGTACTCCGTTTAGCAATGTTAGTTTACCCTTTATAAGGGCGAAATTGGAGAAGC
TAGGGCCACATTTTAAGCATCTTGGTACATGTGTTCCCAGGGGTCCTTCCAAATATGAATTTATAGGTGAAGCTGCTTTT
GCAGATGAAGTTATTTCATTTAAGAAAAGAAACTTTTATATGTCCGATGTGATCAGCAGGGCTTCTAGTACGATGGCAAA
GTGTAGTGAGGAGTTTAATGCTTTATCTTGTTCTCTCTAA

Upstream 100 bases:

>100_bases
AAATATTTCCTACATGGGTGCGGAGTATGAGAACGGTGATCCTGTCGAAAGTGATGATTCGTCTGGTATGCCAGTCAGGT
GGGATAGTATCTAGAAGTTT

Downstream 100 bases:

>100_bases
GCTTGTTTGGATAGTACTGCTTGCAATAGTCTTGATACTTTGTGTGGCCTACCTGACATATGCAGAGAGAAAGGTAATAG
CAGCAACACAACTTCGTGTC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MPNVTINGKKLLVESGCTVIQACQMAGVEVPRFCYHERLKIAGNCRMCLVEVEGGPPKLAASCATPVVDNMVVHTDTPKI
RAAREGVMEFLLANHPLDCPICDQGGECDLQDQAILYGKGEGRFSYAKRSVQKKDFGPVISTEMNRCIHCTRCIRFLSDV
AGVEELGMVNRGADSEISTYIQKSLSSELSGNIIDLCPVGALTSKPYAFTARPWELTKIESVDVLDAVGSNIRIDVRGQT
VMRILPRLNEEINEEWLSDRSRFSYDGLRVQRLDRCYVRVNGKLHESTWKKAISEIVKQIDHVNREEIAAVAGDLADVES
VFLLKRMLNKLGVSKTECRQDGASYMVSERDFYTFNTTFAGIEESDFCFLVGANLRVDAPLIAARIRKRWLSGNYTVVGL
GSDAKYAFDVSSIGNDAATLVEIASGRNQKFQELLGSSRRPMMIVGPDVLSRADANYIISLLRAIAERFGFFQESFNGFS
VLQRHSGTVGALDVGFYHQDGLKGVLNGDTKLVYLLGADDCVESIPEGAFVVYQGHHGDKGASRANVILPGCSYVEKDAI
YVNAEGRAQLAFRAVFPPGEARDDREIIAELAQALGTPFSNVSLPFIRAKLEKLGPHFKHLGTCVPRGPSKYEFIGEAAF
ADEVISFKKRNFYMSDVISRASSTMAKCSEEFNALSCSL

Sequences:

>Translated_679_residues
MPNVTINGKKLLVESGCTVIQACQMAGVEVPRFCYHERLKIAGNCRMCLVEVEGGPPKLAASCATPVVDNMVVHTDTPKI
RAAREGVMEFLLANHPLDCPICDQGGECDLQDQAILYGKGEGRFSYAKRSVQKKDFGPVISTEMNRCIHCTRCIRFLSDV
AGVEELGMVNRGADSEISTYIQKSLSSELSGNIIDLCPVGALTSKPYAFTARPWELTKIESVDVLDAVGSNIRIDVRGQT
VMRILPRLNEEINEEWLSDRSRFSYDGLRVQRLDRCYVRVNGKLHESTWKKAISEIVKQIDHVNREEIAAVAGDLADVES
VFLLKRMLNKLGVSKTECRQDGASYMVSERDFYTFNTTFAGIEESDFCFLVGANLRVDAPLIAARIRKRWLSGNYTVVGL
GSDAKYAFDVSSIGNDAATLVEIASGRNQKFQELLGSSRRPMMIVGPDVLSRADANYIISLLRAIAERFGFFQESFNGFS
VLQRHSGTVGALDVGFYHQDGLKGVLNGDTKLVYLLGADDCVESIPEGAFVVYQGHHGDKGASRANVILPGCSYVEKDAI
YVNAEGRAQLAFRAVFPPGEARDDREIIAELAQALGTPFSNVSLPFIRAKLEKLGPHFKHLGTCVPRGPSKYEFIGEAAF
ADEVISFKKRNFYMSDVISRASSTMAKCSEEFNALSCSL
>Mature_678_residues
PNVTINGKKLLVESGCTVIQACQMAGVEVPRFCYHERLKIAGNCRMCLVEVEGGPPKLAASCATPVVDNMVVHTDTPKIR
AAREGVMEFLLANHPLDCPICDQGGECDLQDQAILYGKGEGRFSYAKRSVQKKDFGPVISTEMNRCIHCTRCIRFLSDVA
GVEELGMVNRGADSEISTYIQKSLSSELSGNIIDLCPVGALTSKPYAFTARPWELTKIESVDVLDAVGSNIRIDVRGQTV
MRILPRLNEEINEEWLSDRSRFSYDGLRVQRLDRCYVRVNGKLHESTWKKAISEIVKQIDHVNREEIAAVAGDLADVESV
FLLKRMLNKLGVSKTECRQDGASYMVSERDFYTFNTTFAGIEESDFCFLVGANLRVDAPLIAARIRKRWLSGNYTVVGLG
SDAKYAFDVSSIGNDAATLVEIASGRNQKFQELLGSSRRPMMIVGPDVLSRADANYIISLLRAIAERFGFFQESFNGFSV
LQRHSGTVGALDVGFYHQDGLKGVLNGDTKLVYLLGADDCVESIPEGAFVVYQGHHGDKGASRANVILPGCSYVEKDAIY
VNAEGRAQLAFRAVFPPGEARDDREIIAELAQALGTPFSNVSLPFIRAKLEKLGPHFKHLGTCVPRGPSKYEFIGEAAFA
DEVISFKKRNFYMSDVISRASSTMAKCSEEFNALSCSL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=682, Percent_Identity=46.0410557184751, Blast_Score=624, Evalue=1e-179,
Organism=Escherichia coli, GI145693161, Length=650, Percent_Identity=25.0769230769231, Blast_Score=199, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17565758, Length=691, Percent_Identity=43.5600578871201, Blast_Score=570, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI32566231, Length=576, Percent_Identity=47.3958333333333, Blast_Score=533, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI193209088, Length=250, Percent_Identity=58.4, Blast_Score=318, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24640559, Length=672, Percent_Identity=46.1309523809524, Blast_Score=600, Evalue=1e-171,
Organism=Drosophila melanogaster, GI24640557, Length=672, Percent_Identity=46.1309523809524, Blast_Score=600, Evalue=1e-171,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74762; Mature: 74631

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNVTINGKKLLVESGCTVIQACQMAGVEVPRFCYHERLKIAGNCRMCLVEVEGGPPKLA
CCCCEECCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
ASCATPVVDNMVVHTDTPKIRAAREGVMEFLLANHPLDCPICDQGGECDLQDQAILYGKG
HHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECC
EGRFSYAKRSVQKKDFGPVISTEMNRCIHCTRCIRFLSDVAGVEELGMVNRGADSEISTY
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHH
IQKSLSSELSGNIIDLCPVGALTSKPYAFTARPWELTKIESVDVLDAVGSNIRIDVRGQT
HHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCEEEEECCCHHHHHCCCCEEEEECCHH
VMRILPRLNEEINEEWLSDRSRFSYDGLRVQRLDRCYVRVNGKLHESTWKKAISEIVKQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCEECHHHHHHHHHHHHHHH
DHVNREEIAAVAGDLADVESVFLLKRMLNKLGVSKTECRQDGASYMVSERDFYTFNTTFA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEEECEEC
GIEESDFCFLVGANLRVDAPLIAARIRKRWLSGNYTVVGLGSDAKYAFDVSSIGNDAATL
CCCCCCEEEEEECCCEECCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHCCCCHHHH
VEIASGRNQKFQELLGSSRRPMMIVGPDVLSRADANYIISLLRAIAERFGFFQESFNGFS
HHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
VLQRHSGTVGALDVGFYHQDGLKGVLNGDTKLVYLLGADDCVESIPEGAFVVYQGHHGDK
HHHHCCCCEEEEEECEEECCCCCEEECCCCEEEEEECCHHHHHHCCCCEEEEEECCCCCC
GASRANVILPGCSYVEKDAIYVNAEGRAQLAFRAVFPPGEARDDREIIAELAQALGTPFS
CCCCCEEEECCCCEECCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
NVSLPFIRAKLEKLGPHFKHLGTCVPRGPSKYEFIGEAAFADEVISFKKRNFYMSDVISR
CCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ASSTMAKCSEEFNALSCSL
HHHHHHHHHHHHCCEECCC
>Mature Secondary Structure 
PNVTINGKKLLVESGCTVIQACQMAGVEVPRFCYHERLKIAGNCRMCLVEVEGGPPKLA
CCCEECCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
ASCATPVVDNMVVHTDTPKIRAAREGVMEFLLANHPLDCPICDQGGECDLQDQAILYGKG
HHHCCHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECC
EGRFSYAKRSVQKKDFGPVISTEMNRCIHCTRCIRFLSDVAGVEELGMVNRGADSEISTY
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHH
IQKSLSSELSGNIIDLCPVGALTSKPYAFTARPWELTKIESVDVLDAVGSNIRIDVRGQT
HHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCEEEEECCCHHHHHCCCCEEEEECCHH
VMRILPRLNEEINEEWLSDRSRFSYDGLRVQRLDRCYVRVNGKLHESTWKKAISEIVKQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCEECHHHHHHHHHHHHHHH
DHVNREEIAAVAGDLADVESVFLLKRMLNKLGVSKTECRQDGASYMVSERDFYTFNTTFA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEEECEEC
GIEESDFCFLVGANLRVDAPLIAARIRKRWLSGNYTVVGLGSDAKYAFDVSSIGNDAATL
CCCCCCEEEEEECCCEECCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHCCCCHHHH
VEIASGRNQKFQELLGSSRRPMMIVGPDVLSRADANYIISLLRAIAERFGFFQESFNGFS
HHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
VLQRHSGTVGALDVGFYHQDGLKGVLNGDTKLVYLLGADDCVESIPEGAFVVYQGHHGDK
HHHHCCCCEEEEEECEEECCCCCEEECCCCEEEEEECCHHHHHHCCCCEEEEEECCCCCC
GASRANVILPGCSYVEKDAIYVNAEGRAQLAFRAVFPPGEARDDREIIAELAQALGTPFS
CCCCCEEEECCCCEECCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
NVSLPFIRAKLEKLGPHFKHLGTCVPRGPSKYEFIGEAAFADEVISFKKRNFYMSDVISR
CCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ASSTMAKCSEEFNALSCSL
HHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA