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The map label for this gene is murB [H]

Identifier: 88607997

GI number: 88607997

Start: 510863

End: 511711

Strand: Reverse

Name: murB [H]

Synonym: NSE_0590

Alternate gene names: 88607997

Gene position: 511711-510863 (Counterclockwise)

Preceding gene: 88608420

Following gene: 88608572

Centisome position: 59.57

GC content: 41.93

Gene sequence:

>849_bases
TTGCGCAACGCGAAGTATAAGCTGAAGGAAGTTGAGTTAAGTAGATATACTCGGCTCAGAGTTGGAGGTAAGACCAAGTT
ACTTTACGCAGCAAATGTAAATGAAATTGTGCATTTCACTAAGAATCACAATTTCCATGTTATAGGTGCTGGATCCAATA
TTCTTGCAGGCCAAGTGTTAGACAAGCCCATTTTGAAACTGGGGAAAGGCTTTGAGTATGTATCATACGCAGATGGAAAA
GTGAAAGTCGGAGCGGCAGTACTTACATCGACTCTGGCGAGATTTGCACTTGAGAATGAGATTGGTGCTTTTGAGTTTTT
TGCGGTTATGCACCGGACTATCGGAAGTGCTATCACAATGAATACGGGTGTTTATGATCAGAGGGTCTCAGACCTTTTAG
TAGCTGCAACTTTTATTGATGAGAATGGAGAGATGCTCACACTTTCTCGTGAGGAAATAGGTTTTAAAAATGGGGGCAAC
TCATTGCCGAAGAATTACATCTGTGTTGAGGCAGTTTTCGATGCTGGATGTAAGATGCAGAAGGAGAAGATAAAACTGCT
GACACTCGAGATGTTAAGAAAAAGCCAGGATTTCCAACCTGCATTTTCTGAATCAGCCTGTCAGCTTTTTCAGGATCTAC
CAGAACAAAAAGCCTGTGAGCTTATTGCCAAGGCTGGATATGCAGGGTTTTCTGTAGGGTGTGCAAGGATTTCCGAAAAG
TACAACAATTTCATCATAAGTGGTGGGTGCAAGACAGCTGATCCACTTTTAGAGCTTTGTTACGTTGTGAGAAATGGGAT
AAAAAACAGATTGGGAGTTACCCTGGATTTTTCGGTGGTCTTCATATGA

Upstream 100 bases:

>100_bases
AACATTTATCCTATAACTTTACAAACTAAAAGTCTGCCCCTTGGAACATGGCAGCAGAGATTGCTAAGATATCACGATAT
TTGTTTTATTTCTATGAATC

Downstream 100 bases:

>100_bases
GACTTTATTCATGAGTGGGGAATAATGAATAACACACAAAGTTCATTTACGTAATTTTGTTTCACACAGTGATGGATGTA
AGGTGTGCATGATGTGCTTG

Product: putative UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRNAKYKLKEVELSRYTRLRVGGKTKLLYAANVNEIVHFTKNHNFHVIGAGSNILAGQVLDKPILKLGKGFEYVSYADGK
VKVGAAVLTSTLARFALENEIGAFEFFAVMHRTIGSAITMNTGVYDQRVSDLLVAATFIDENGEMLTLSREEIGFKNGGN
SLPKNYICVEAVFDAGCKMQKEKIKLLTLEMLRKSQDFQPAFSESACQLFQDLPEQKACELIAKAGYAGFSVGCARISEK
YNNFIISGGCKTADPLLELCYVVRNGIKNRLGVTLDFSVVFI

Sequences:

>Translated_282_residues
MRNAKYKLKEVELSRYTRLRVGGKTKLLYAANVNEIVHFTKNHNFHVIGAGSNILAGQVLDKPILKLGKGFEYVSYADGK
VKVGAAVLTSTLARFALENEIGAFEFFAVMHRTIGSAITMNTGVYDQRVSDLLVAATFIDENGEMLTLSREEIGFKNGGN
SLPKNYICVEAVFDAGCKMQKEKIKLLTLEMLRKSQDFQPAFSESACQLFQDLPEQKACELIAKAGYAGFSVGCARISEK
YNNFIISGGCKTADPLLELCYVVRNGIKNRLGVTLDFSVVFI
>Mature_282_residues
MRNAKYKLKEVELSRYTRLRVGGKTKLLYAANVNEIVHFTKNHNFHVIGAGSNILAGQVLDKPILKLGKGFEYVSYADGK
VKVGAAVLTSTLARFALENEIGAFEFFAVMHRTIGSAITMNTGVYDQRVSDLLVAATFIDENGEMLTLSREEIGFKNGGN
SLPKNYICVEAVFDAGCKMQKEKIKLLTLEMLRKSQDFQPAFSESACQLFQDLPEQKACELIAKAGYAGFSVGCARISEK
YNNFIISGGCKTADPLLELCYVVRNGIKNRLGVTLDFSVVFI

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 31125; Mature: 31125

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNAKYKLKEVELSRYTRLRVGGKTKLLYAANVNEIVHFTKNHNFHVIGAGSNILAGQVL
CCCCCCHHHHHHHHHHHEEEECCCEEEEEEECHHHHEEEECCCCEEEEECCCCEEEHHHH
DKPILKLGKGFEYVSYADGKVKVGAAVLTSTLARFALENEIGAFEFFAVMHRTIGSAITM
HHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEE
NTGVYDQRVSDLLVAATFIDENGEMLTLSREEIGFKNGGNSLPKNYICVEAVFDAGCKMQ
CCCCHHHHHHHHHHHHEEECCCCCEEEEEHHHCCCCCCCCCCCCCCEEHHHHHCCCCCCC
KEKIKLLTLEMLRKSQDFQPAFSESACQLFQDLPEQKACELIAKAGYAGFSVGCARISEK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
YNNFIISGGCKTADPLLELCYVVRNGIKNRLGVTLDFSVVFI
HCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEC
>Mature Secondary Structure
MRNAKYKLKEVELSRYTRLRVGGKTKLLYAANVNEIVHFTKNHNFHVIGAGSNILAGQVL
CCCCCCHHHHHHHHHHHEEEECCCEEEEEEECHHHHEEEECCCCEEEEECCCCEEEHHHH
DKPILKLGKGFEYVSYADGKVKVGAAVLTSTLARFALENEIGAFEFFAVMHRTIGSAITM
HHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEE
NTGVYDQRVSDLLVAATFIDENGEMLTLSREEIGFKNGGNSLPKNYICVEAVFDAGCKMQ
CCCCHHHHHHHHHHHHEEECCCCCEEEEEHHHCCCCCCCCCCCCCCEEHHHHHCCCCCCC
KEKIKLLTLEMLRKSQDFQPAFSESACQLFQDLPEQKACELIAKAGYAGFSVGCARISEK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
YNNFIISGGCKTADPLLELCYVVRNGIKNRLGVTLDFSVVFI
HCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]