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The map label for this gene is mrp [H]

Identifier: 88607940

GI number: 88607940

Start: 1170067

End: 1171095

Strand: Reverse

Name: mrp [H]

Synonym: APH_1111

Alternate gene names: 88607940

Gene position: 1171095-1170067 (Counterclockwise)

Preceding gene: 88607871

Following gene: 88607021

Centisome position: 79.6

GC content: 42.37

Gene sequence:

>1029_bases
ATGGTTACTGAACAGGAAGTGCTCTGCGTGTTACAGGATGTTACCGATCATGATACCAGAAAAAAGGTCGCAGACATTGG
TAAACTGTCAGTTACTATCAATAAAAGCGATTTGGGAATAATATTACATGTTTCTGAACCAAAGAGTGCTCTCTGGGAAC
AGCAGTTCAAAGATAATTGCTCTACCATAATAAAGAGTAAAATACCGGGCATTTCCAGCATTACCGTTGCTTTAGTGATG
GCAAAACAGCAAAGTAATGTTCCAAAAAGGGTCAAACTCAAGGGTATAAAAAATGTGCTACTTGTTTCTTCAGGGAAGGG
AGGGGTAGGTAAGTCCACTGTGGCCGCGCAGCTGGCATTAACGTTGTCAGCACTAGGATATAAAATTGCTCTAGTTGATG
CAGATATTTACGGGCCATCTATTCCTAGATTGTTGGGAATTGGAGTATTGGCTGAGGTTGACAACGACGGAATGATGATC
CCGGTAGAGATGCACGGGCTGCAAAGCATTTCCATTGGTAACATCATAGAGGATCAAGATAAAGCCCTGGTATGGCGTGG
TCCGATGCTCACAAAGGCAATAAATAAGTTGATCATGGGTACAAGATGGGCTGCCAGAGACTATATGATTATCGATACTC
CTCCAGGTACTGGGGATGTACATATTAGTCTCACGCAAGGGTATAGTATTACGGGTGCCGTTGTCGTATCAACGCCTCAT
GAACTATCAGTAATACATGCCATGAAGACATGTGATATGCTCAAAAGCCTTGATGTTAAGTTGCTCGGTATCGTGGAAAA
TATGAGCTATTTTCTTGATGTGGATACAGGTAAGAAAACGCACCTTTTTGGTGAAGGAGGCGGACAGGAAATAGCTGAGA
GGGCTGATTCAACATTGTTGGGTATGGTTAGCATTCATCCCAAAATCCACCTTCCTTCGGTAAACAAGCGTTTAAGCCCA
TTAGATAATGAGTTCTGCAACGCATACGAAAAGATTGTCGCTAATATAATTAGAAGCGTAAGTTCCTGA

Upstream 100 bases:

>100_bases
TAACTACGAGGGCATGATAATTAGGTGTGTTACAAAAGTAAACATGTTTTACCATAACTATGGTACACATTAGGAGTTAT
TCCTTAAATTGTTACAAATT

Downstream 100 bases:

>100_bases
CGTTCCAGAAGTAGTATTCTTAACATCAAAACGCTTTTGTTTTTGGAGTACATACTCTCCAGTTCTACAAAGTTTGTAGT
GACTCCATGATATGAAGATC

Product: ATP-binding Mrp/Nbp35 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVTEQEVLCVLQDVTDHDTRKKVADIGKLSVTINKSDLGIILHVSEPKSALWEQQFKDNCSTIIKSKIPGISSITVALVM
AKQQSNVPKRVKLKGIKNVLLVSSGKGGVGKSTVAAQLALTLSALGYKIALVDADIYGPSIPRLLGIGVLAEVDNDGMMI
PVEMHGLQSISIGNIIEDQDKALVWRGPMLTKAINKLIMGTRWAARDYMIIDTPPGTGDVHISLTQGYSITGAVVVSTPH
ELSVIHAMKTCDMLKSLDVKLLGIVENMSYFLDVDTGKKTHLFGEGGGQEIAERADSTLLGMVSIHPKIHLPSVNKRLSP
LDNEFCNAYEKIVANIIRSVSS

Sequences:

>Translated_342_residues
MVTEQEVLCVLQDVTDHDTRKKVADIGKLSVTINKSDLGIILHVSEPKSALWEQQFKDNCSTIIKSKIPGISSITVALVM
AKQQSNVPKRVKLKGIKNVLLVSSGKGGVGKSTVAAQLALTLSALGYKIALVDADIYGPSIPRLLGIGVLAEVDNDGMMI
PVEMHGLQSISIGNIIEDQDKALVWRGPMLTKAINKLIMGTRWAARDYMIIDTPPGTGDVHISLTQGYSITGAVVVSTPH
ELSVIHAMKTCDMLKSLDVKLLGIVENMSYFLDVDTGKKTHLFGEGGGQEIAERADSTLLGMVSIHPKIHLPSVNKRLSP
LDNEFCNAYEKIVANIIRSVSS
>Mature_342_residues
MVTEQEVLCVLQDVTDHDTRKKVADIGKLSVTINKSDLGIILHVSEPKSALWEQQFKDNCSTIIKSKIPGISSITVALVM
AKQQSNVPKRVKLKGIKNVLLVSSGKGGVGKSTVAAQLALTLSALGYKIALVDADIYGPSIPRLLGIGVLAEVDNDGMMI
PVEMHGLQSISIGNIIEDQDKALVWRGPMLTKAINKLIMGTRWAARDYMIIDTPPGTGDVHISLTQGYSITGAVVVSTPH
ELSVIHAMKTCDMLKSLDVKLLGIVENMSYFLDVDTGKKTHLFGEGGGQEIAERADSTLLGMVSIHPKIHLPSVNKRLSP
LDNEFCNAYEKIVANIIRSVSS

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=261, Percent_Identity=37.5478927203065, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI6912540, Length=223, Percent_Identity=39.4618834080717, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI118572611, Length=274, Percent_Identity=33.2116788321168, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI87082045, Length=309, Percent_Identity=39.4822006472492, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25143050, Length=236, Percent_Identity=36.864406779661, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322188, Length=238, Percent_Identity=38.2352941176471, Blast_Score=173, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6321347, Length=256, Percent_Identity=35.9375, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221511043, Length=197, Percent_Identity=40.1015228426396, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24667611, Length=223, Percent_Identity=39.4618834080717, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19921440, Length=263, Percent_Identity=32.6996197718631, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 36902; Mature: 36902

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTEQEVLCVLQDVTDHDTRKKVADIGKLSVTINKSDLGIILHVSEPKSALWEQQFKDNC
CCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHH
STIIKSKIPGISSITVALVMAKQQSNVPKRVKLKGIKNVLLVSSGKGGVGKSTVAAQLAL
HHHHHHCCCCCHHHHHHEEEEHHHCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHH
TLSALGYKIALVDADIYGPSIPRLLGIGVLAEVDNDGMMIPVEMHGLQSISIGNIIEDQD
HHHHCCEEEEEEEECCCCCCCHHHHCCCEEEEECCCCEEEEEEECCCCEEECCCEECCCC
KALVWRGPMLTKAINKLIMGTRWAARDYMIIDTPPGTGDVHISLTQGYSITGAVVVSTPH
CEEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEEEECCC
ELSVIHAMKTCDMLKSLDVKLLGIVENMSYFLDVDTGKKTHLFGEGGGQEIAERADSTLL
HHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHCCCEEE
GMVSIHPKIHLPSVNKRLSPLDNEFCNAYEKIVANIIRSVSS
EEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTEQEVLCVLQDVTDHDTRKKVADIGKLSVTINKSDLGIILHVSEPKSALWEQQFKDNC
CCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHH
STIIKSKIPGISSITVALVMAKQQSNVPKRVKLKGIKNVLLVSSGKGGVGKSTVAAQLAL
HHHHHHCCCCCHHHHHHEEEEHHHCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHH
TLSALGYKIALVDADIYGPSIPRLLGIGVLAEVDNDGMMIPVEMHGLQSISIGNIIEDQD
HHHHCCEEEEEEEECCCCCCCHHHHCCCEEEEECCCCEEEEEEECCCCEEECCCEECCCC
KALVWRGPMLTKAINKLIMGTRWAARDYMIIDTPPGTGDVHISLTQGYSITGAVVVSTPH
CEEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEEEECCC
ELSVIHAMKTCDMLKSLDVKLLGIVENMSYFLDVDTGKKTHLFGEGGGQEIAERADSTLL
HHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHCCCEEE
GMVSIHPKIHLPSVNKRLSPLDNEFCNAYEKIVANIIRSVSS
EEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]