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The map label for this gene is efp

Identifier: 88607917

GI number: 88607917

Start: 573226

End: 573792

Strand: Direct

Name: efp

Synonym: APH_0547

Alternate gene names: 88607917

Gene position: 573226-573792 (Clockwise)

Preceding gene: 88607139

Following gene: 88607635

Centisome position: 38.96

GC content: 41.8

Gene sequence:

>567_bases
ATGGCTGAAAGAGGGAATGACATACGGCCAGGTCAAGTTTTGGATCATAATGGGGCTCTGTATCTAGTTGTGAAAACTAT
GCATACGCAGCCTGGTAAGGGTGGAGCATATATTCAGGCTGAGTTAAAAAATCTGAAAACTGGTGCTAAGTATCAGGAGA
GGTTTCGTGCTGATGGATATGTAAACCGTGCCATTATAGAAGAGGTCAGTTTTCAGTATATTTTTGGGGATTCATCTTCG
CTTACTTTAATGAATACTGAGAATTATGAGCAGATTTCTATACCCGTGGAGCTGTTGGGAGATAAAAGTGTATACCTTCA
GGAGAATATGATACTAACCCTGCTTTTCCACAAAGGTCAGGTGATATCAGCTAAGGTTCCTGATTATGTTGTGCTTGAGG
TTGTGGAGGCAGAGTCAGTTATCAAGGGGCAGACTGCTTCCTCATCATATAAGTCTGCGGTATTGGAAAATGGGCGTCGT
GTGAGTGTACCGCCGTTTATAAAAGTTGGAGAAAAGATAGTAATTTACACTCCTGATGACACGTATTACGAGAGGGCAAA
AGACTAA

Upstream 100 bases:

>100_bases
GCATTACGTGCTGAGTATCAAATGCAGGATTGTTCTTAATTTTTTACTTGAGTTGTAGTATTCTTGCGCATAGAATTCAC
GTTCGTTCTTGGAGGTAGCT

Downstream 100 bases:

>100_bases
GTATGGTAGCTTTATTCTCGCCTATTATAGGGGTTATGATCAATGCAGTGCGCAAGTCATCACGTGGCTTAGTGCGGGAT
TTTAATGAAATTAGGTATTT

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAERGNDIRPGQVLDHNGALYLVVKTMHTQPGKGGAYIQAELKNLKTGAKYQERFRADGYVNRAIIEEVSFQYIFGDSSS
LTLMNTENYEQISIPVELLGDKSVYLQENMILTLLFHKGQVISAKVPDYVVLEVVEAESVIKGQTASSSYKSAVLENGRR
VSVPPFIKVGEKIVIYTPDDTYYERAKD

Sequences:

>Translated_188_residues
MAERGNDIRPGQVLDHNGALYLVVKTMHTQPGKGGAYIQAELKNLKTGAKYQERFRADGYVNRAIIEEVSFQYIFGDSSS
LTLMNTENYEQISIPVELLGDKSVYLQENMILTLLFHKGQVISAKVPDYVVLEVVEAESVIKGQTASSSYKSAVLENGRR
VSVPPFIKVGEKIVIYTPDDTYYERAKD
>Mature_187_residues
AERGNDIRPGQVLDHNGALYLVVKTMHTQPGKGGAYIQAELKNLKTGAKYQERFRADGYVNRAIIEEVSFQYIFGDSSSL
TLMNTENYEQISIPVELLGDKSVYLQENMILTLLFHKGQVISAKVPDYVVLEVVEAESVIKGQTASSSYKSAVLENGRRV
SVPPFIKVGEKIVIYTPDDTYYERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=31.3186813186813, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ANAPZ (Q2GKG2)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505139.1
- STRING:   Q2GKG2
- GeneID:   3931310
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0547
- NMPDR:   fig|212042.5.peg.538
- TIGR:   APH_0547
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2GKG2
- ProtClustDB:   PRK00529
- BioCyc:   APHA212042:APH_0547-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21028; Mature: 20897

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERGNDIRPGQVLDHNGALYLVVKTMHTQPGKGGAYIQAELKNLKTGAKYQERFRADGY
CCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCC
VNRAIIEEVSFQYIFGDSSSLTLMNTENYEQISIPVELLGDKSVYLQENMILTLLFHKGQ
HHHHHHHHCCEEEEECCCCCEEEEECCCCEEEEEEEEEECCCEEEEECCEEEEEEEECCE
VISAKVPDYVVLEVVEAESVIKGQTASSSYKSAVLENGRRVSVPPFIKVGEKIVIYTPDD
EEEECCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHCCCEECCCCHHCCCCEEEEECCCC
TYYERAKD
CHHHCCCC
>Mature Secondary Structure 
AERGNDIRPGQVLDHNGALYLVVKTMHTQPGKGGAYIQAELKNLKTGAKYQERFRADGY
CCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCC
VNRAIIEEVSFQYIFGDSSSLTLMNTENYEQISIPVELLGDKSVYLQENMILTLLFHKGQ
HHHHHHHHCCEEEEECCCCCEEEEECCCCEEEEEEEEEECCCEEEEECCEEEEEEEECCE
VISAKVPDYVVLEVVEAESVIKGQTASSSYKSAVLENGRRVSVPPFIKVGEKIVIYTPDD
EEEECCCCEEEEEEECHHHHHCCCCCCCHHHHHHHHCCCEECCCCHHCCCCEEEEECCCC
TYYERAKD
CHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA