Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 88607904

GI number: 88607904

Start: 678443

End: 679627

Strand: Direct

Name: aspC [H]

Synonym: APH_0660

Alternate gene names: 88607904

Gene position: 678443-679627 (Clockwise)

Preceding gene: 88606738

Following gene: 88607926

Centisome position: 46.11

GC content: 43.38

Gene sequence:

>1185_bases
ATGCTAAGCGAAAGGATGAATTGTATCAAACCGTCACCTACCTTAGAGCTTTCTAGACTTACGTTAGAACTTAGGGCTCA
AGGGCTTGACATAATATCTCTAGGTGCAGGGGAACCCGACTTTGATACTCCAGATCATGTAAAGGATGCGGCGATTGCTG
CCATTAATGCAGGAAAAACTAAATACACTCCAGTGGAAGGTATTCCCGAATTGAAAGATTCCATTATTCGCAGTGTGCGT
CGGGACTATGGTATAGACTACGTAGCAAATCAAGTATTAGTAGGGGCTGGGGCTAAGCAGTGCATATATAACCTGTTTAT
GGCTACCATAAACGAGGGAGATGAGGTTATTATTCCTGCGCCGTATTGGGTTTCGTATCCAGACATGGTAAAAATAGCAG
GGGGAGCTCCAGTTATTGTAAATTGCGGTGACTATTTGAAGTTGACTCCAGAATTACTTCGTGGAGCAATAACCCCGAAG
ACTAAATGGCTCATTATTAACTCTCCGTCCAACCCTACCGGTGCAGTGTATAGTAGAGAAGAGTTAGCCGCTATAGCAGA
GGTTTTAAAGCAGCATAAACATGTCTTAGTTATTACTGATGACATATACGCAAAGCTTGTCTATGATGCTGAGTTTTGCG
GCATTCTGCAGGTAGAACCATCACTTTATGATAGAGTCTATATAGTTAATGGGGTCTCAAAAGCGTATTCCATGACAGGC
TGGCGGATAGGGTACATATTAGGTAACGCGGAAGCTATAAAAGCGGTATCCACAATACAGTCTCAGAGTACAACTAATGC
TAATTCCATAGCGCAGTATGCTGCAATAGCCGCGCTGGATGGTGATCAATCTTTTTTAGACACTAGAATTAAGGCATTTG
CGCGTAGAAGGGATAGGGTTATGGATGCAGTGCTTTCTTCAGGAGTGTTGCAGGCAGATGTGCCACAAGGAGCCTTTTAT
GTGTTCATATCATGCGGTAATGCGATAGGTAAACACGCTCCTAAAGTTGGTGTGATAAACGACGGAAGTGATATGGCGAA
GCATTTGCTAAATCATAGGGTGGCTGTAGTTCCTGGTGTTGCCTTTGGAGCTCCTAACTTTTTCCGTATTTCATATGCTC
TCTCAGATGATAGGTTATCTGAAGCATGTGAGAGGATTTTGGAGGCTTGTTCGTACCTAAGCTAG

Upstream 100 bases:

>100_bases
TATGCAGTGCTTTAGGTATTGCAAGTGTTCTGATTTAGAGTTAACGAGTTAGGTTAAGAATAGTGGCATCAGGAGTGATG
CATTTCAATGGGGGATATGT

Downstream 100 bases:

>100_bases
CATTTGGTGTTAGGGGTTTAGAAAAAATTACTGAGTTGCAGATGTGGATCTTAAGTGCTCTGTGGTAGGGTAAGATTGAG
CTTGGGGTAGAAGTCTTGCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLSERMNCIKPSPTLELSRLTLELRAQGLDIISLGAGEPDFDTPDHVKDAAIAAINAGKTKYTPVEGIPELKDSIIRSVR
RDYGIDYVANQVLVGAGAKQCIYNLFMATINEGDEVIIPAPYWVSYPDMVKIAGGAPVIVNCGDYLKLTPELLRGAITPK
TKWLIINSPSNPTGAVYSREELAAIAEVLKQHKHVLVITDDIYAKLVYDAEFCGILQVEPSLYDRVYIVNGVSKAYSMTG
WRIGYILGNAEAIKAVSTIQSQSTTNANSIAQYAAIAALDGDQSFLDTRIKAFARRRDRVMDAVLSSGVLQADVPQGAFY
VFISCGNAIGKHAPKVGVINDGSDMAKHLLNHRVAVVPGVAFGAPNFFRISYALSDDRLSEACERILEACSYLS

Sequences:

>Translated_394_residues
MLSERMNCIKPSPTLELSRLTLELRAQGLDIISLGAGEPDFDTPDHVKDAAIAAINAGKTKYTPVEGIPELKDSIIRSVR
RDYGIDYVANQVLVGAGAKQCIYNLFMATINEGDEVIIPAPYWVSYPDMVKIAGGAPVIVNCGDYLKLTPELLRGAITPK
TKWLIINSPSNPTGAVYSREELAAIAEVLKQHKHVLVITDDIYAKLVYDAEFCGILQVEPSLYDRVYIVNGVSKAYSMTG
WRIGYILGNAEAIKAVSTIQSQSTTNANSIAQYAAIAALDGDQSFLDTRIKAFARRRDRVMDAVLSSGVLQADVPQGAFY
VFISCGNAIGKHAPKVGVINDGSDMAKHLLNHRVAVVPGVAFGAPNFFRISYALSDDRLSEACERILEACSYLS
>Mature_394_residues
MLSERMNCIKPSPTLELSRLTLELRAQGLDIISLGAGEPDFDTPDHVKDAAIAAINAGKTKYTPVEGIPELKDSIIRSVR
RDYGIDYVANQVLVGAGAKQCIYNLFMATINEGDEVIIPAPYWVSYPDMVKIAGGAPVIVNCGDYLKLTPELLRGAITPK
TKWLIINSPSNPTGAVYSREELAAIAEVLKQHKHVLVITDDIYAKLVYDAEFCGILQVEPSLYDRVYIVNGVSKAYSMTG
WRIGYILGNAEAIKAVSTIQSQSTTNANSIAQYAAIAALDGDQSFLDTRIKAFARRRDRVMDAVLSSGVLQADVPQGAFY
VFISCGNAIGKHAPKVGVINDGSDMAKHLLNHRVAVVPGVAFGAPNFFRISYALSDDRLSEACERILEACSYLS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=28.498727735369, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=28.498727735369, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=28.1012658227848, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI56713256, Length=395, Percent_Identity=28.1012658227848, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881281, Length=389, Percent_Identity=24.9357326478149, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4507369, Length=387, Percent_Identity=26.3565891472868, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=30.4582210242588, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788627, Length=362, Percent_Identity=29.0055248618785, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=25.4691689008043, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=420, Percent_Identity=26.9047619047619, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=420, Percent_Identity=27.1428571428571, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=420, Percent_Identity=27.1428571428571, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=24.0740740740741, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=27.3182957393484, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573069, Length=423, Percent_Identity=26.7139479905437, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646114, Length=423, Percent_Identity=26.7139479905437, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573067, Length=423, Percent_Identity=26.7139479905437, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573065, Length=423, Percent_Identity=26.7139479905437, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=24.6113989637306, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42766; Mature: 42766

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSERMNCIKPSPTLELSRLTLELRAQGLDIISLGAGEPDFDTPDHVKDAAIAAINAGKT
CCCCCCCCCCCCCCEEHHHEEEEHHHCCCCEEEECCCCCCCCCCCHHHHHHHEEEECCCC
KYTPVEGIPELKDSIIRSVRRDYGIDYVANQVLVGAGAKQCIYNLFMATINEGDEVIIPA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHEECCCHHHHHHHHHHHHHCCCCEEEECC
PYWVSYPDMVKIAGGAPVIVNCGDYLKLTPELLRGAITPKTKWLIINSPSNPTGAVYSRE
CCCCCCCCCEEECCCCEEEEECCCCEEECHHHHCCCCCCCEEEEEEECCCCCCCCEECHH
ELAAIAEVLKQHKHVLVITDDIYAKLVYDAEFCGILQVEPSLYDRVYIVNGVSKAYSMTG
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEECCCHHCEEEEEECCHHHHHCCC
WRIGYILGNAEAIKAVSTIQSQSTTNANSIAQYAAIAALDGDQSFLDTRIKAFARRRDRV
EEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHH
MDAVLSSGVLQADVPQGAFYVFISCGNAIGKHAPKVGVINDGSDMAKHLLNHRVAVVPGV
HHHHHHCCCEEECCCCCEEEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHCCEEEECCC
AFGAPNFFRISYALSDDRLSEACERILEACSYLS
CCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSERMNCIKPSPTLELSRLTLELRAQGLDIISLGAGEPDFDTPDHVKDAAIAAINAGKT
CCCCCCCCCCCCCCEEHHHEEEEHHHCCCCEEEECCCCCCCCCCCHHHHHHHEEEECCCC
KYTPVEGIPELKDSIIRSVRRDYGIDYVANQVLVGAGAKQCIYNLFMATINEGDEVIIPA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHEECCCHHHHHHHHHHHHHCCCCEEEECC
PYWVSYPDMVKIAGGAPVIVNCGDYLKLTPELLRGAITPKTKWLIINSPSNPTGAVYSRE
CCCCCCCCCEEECCCCEEEEECCCCEEECHHHHCCCCCCCEEEEEEECCCCCCCCEECHH
ELAAIAEVLKQHKHVLVITDDIYAKLVYDAEFCGILQVEPSLYDRVYIVNGVSKAYSMTG
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEECCCHHCEEEEEECCHHHHHCCC
WRIGYILGNAEAIKAVSTIQSQSTTNANSIAQYAAIAALDGDQSFLDTRIKAFARRRDRV
EEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHH
MDAVLSSGVLQADVPQGAFYVFISCGNAIGKHAPKVGVINDGSDMAKHLLNHRVAVVPGV
HHHHHHCCCEEECCCCCEEEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHCCEEEECCC
AFGAPNFFRISYALSDDRLSEACERILEACSYLS
CCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA