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The map label for this gene is secA

Identifier: 88607849

GI number: 88607849

Start: 1246804

End: 1249425

Strand: Reverse

Name: secA

Synonym: APH_1178

Alternate gene names: 88607849

Gene position: 1249425-1246804 (Counterclockwise)

Preceding gene: 88607638

Following gene: 88607098

Centisome position: 84.92

GC content: 43.48

Gene sequence:

>2622_bases
ATGTTGAGTATAGCGAAGCGTGTATTCTGGCCTTATAGTAGCAGAGCTAAGGGTGCTTCTGTACATAAGATAGTAAAAAG
TATCAACGCGCTGGAAGGGGAGATGGCGGCCCTTTCATCTGAAGCCCTTTTTGGAAAGACCGGTGAGTTTCGGAAAATGT
TGTCTGAGGGCACTGTTACGCTGGATGATCTTCTTGTGCCGGCGTTTGCTGTTGTGCGTGAGGCTTCGCGTAGGGTGTTG
GACATGCGTCACTTCGATGTGCAGCTCATAGGGGGCATTGCATTGCACAGGGGCATGATTGCTGAGATGAAAACTGGTGA
GGGGAAAACGCTGGTTGCAACGCTTGCAGCATATCTAAATGCTCTTGAAAGTAAGGGAGTGCACGTAGTTACTGTGAATG
ACTACTTGGCGGAGCGTGACTCAGAGTGGATGGGGAAGTTGTATAGTGCTCTGGGTATAAGTGTAGGTTGTATCACTAGC
AGTTCGTCTGATGAGGCGCGGAAGGCTGCATATAATTGTGATATTTTGTACTCTACTAATAACGAACTGGGTTTTGATTA
TCTGCGTGATAACATGAAATTCAGTAGGGAAAATATGGTTCAACGTGGCTACAACTACGCTATCGTTGATGAGGTTGACT
CCATATTGATAGATGAGTCGAGAACTCCACTCATAATATCGGGTCCGGTAGAGCGCGACAGCTCGTTATATGGAAAGGTA
GATGCTCTTGTAAGAGATTTAGAGCAGGAAGATTATGACATTGATGAAAAGAGTAAGACGGCATTTTTAACTGAAGATGG
TGCTCTTAAAGTTGAGCAGTTATTGATATCGCACCAGTTAATCCCTGAGGGTTCTTCGCTATACAGCGCGGAGAATATTA
TTATGATGCACTATGTAGGGCAAGCTTTGCGGGCTCATAAGCTGTACTTTGCGGATAAGGACTACATCGTAAAAAACGGT
AGTGTCGTAATAATTGATGAGTTTACCGGTCGTATGATGGATGGTCGGCGTTATTCTGACGGGTTGCATCAGGCCTTGGA
AGCAAAGGAGGGTGTGCGTATTAATAATGAGAACCAAACTCTTGCGTCTACGACATTCCAGAATTACTTCCGCATGTACA
AAAGGTTATCTGGTATGACAGGTACTGCTGAGACGGAAGCTGATGAATTTCTTGGAACGTATAATTTACAAGTTATGCAG
ATTCCAACCAATGTGCCAGTGCAGCGTGTTGATCTTGATGATGACATATACTGCACTGAGGAAGAAAAATATGAAGCGGT
TATAGATTTCATTATTGAGTGTCACAAGAGAAAGCAACCTACGCTTGTAGGCACTATAAGCATTGAGAAATCTGAGCTTC
TCTCAAAGTTACTCACGATGCGTGGTATAAAGCATTCCGTACTTAATGCACGATACCATGAAAAAGAAGCTTACATAATA
GCACAGGCGGGAAAGCCGGGTGCCGTGACTATAGCAACTAATATGGCGGGGCGTGGTACTGATATTAAGCTTGGTGGAAA
CCCTGAGATGTTGGCCAGAAATGAGCTTGCAGGGATTACAGACGAGGAAGAGAGGGCGAAGAGGATAAATAAGATTATCG
AGCAAGCGAAGCATGATAAAGAGATTGTAATGCAGGCAGGTGGGCTTTGTATTATAGGGACTGAGAGGCACGAAAGTAGG
CGTATTGATAATCAATTACGCGGGCGGTCTGGTAGACAGGGTGATCCTGGCTTGTCGAAGTTCTTTCTTTCGTTAGAAGA
TGGTTTGCTGCGTATTTTTGGCTCTGACAAGGTACGAGGCATGTTGAAGCGTCTTGGAATGAAGAGGGGTGAAGCTATAC
AGCATAAATGGATTAATAGGGCCATTGAGCGTGCGCAGAAAAAGGTAGAGGCGAGAAATTACGACATTAGGAAATCGCTA
CTCAGGTTTGACGATGTAATCAATGAGCAGCGCAAGGTAATATTTGCGCAAAGGAATCAGATTCTCGATAGAGAGACATA
TGATTTGGTGCCCTTTTACAGTAATCTTAACTGTGATATCGTATCGCGCATTATCAAAGAGAAGTATTGCGATTTAGGGC
ATAGAGAAACTGCTGAAGAGTTATCCGCAGAGGTTACCAGGATATATGGCATAGAGCTTGATATAGGTGCTCTATCAGCT
CTCGAGACAAGGGAGGAGGTTATAGCATATTTGGATAAGGTTGCAGATGATCTTCTGAAGAAAAAAGCAGATGGGTTTGT
GCATAAGGATGAGAATCTGTGGGATTTTGCGGCGAGGCGCGTGCTAATTACTTCGTTAGACCATCTATGGACTGATCATC
TAGCGGCTTTGGATAGTCTTAAATGCGGGATAAATTTGAGGTCTGTTGGTCAGAAAGATCCGCTTAATGAATTTAAGATT
GAGGCTTTCTATCTACTTGAAAAAATGCTTTCTCGATTTTATGAGATGGTAATCCAAAAGCTTGCTCATATTGAGTTGGA
AGTGCAGCAACAACCTGATGATGGAATGATTAATTTAAATAACTCAACAAGTCAGTTATTTGGTGGCATAGCGCGCAATG
ACAGATGTCCTTGTGGTTCTGGGAAAAAGTTCAAACATTGTCACGGGATGATCAAGGTATAA

Upstream 100 bases:

>100_bases
AAAATTGCGGTAGAAGTGCAGTTGATTACCGAGTCAATTCTGTTGTGCTTTTGAAGACTTGAGCATATAATTCACCCTCC
GATATTCTTGAGTCGTGCTT

Downstream 100 bases:

>100_bases
CTGTGAGAAGCTGTTCTATGGTTCTGGCTAGTAATCTAGCCACATGAGGCCAATATTCTCAAAGTTAACCATGGCATAGG
TTGGAGAAACTCATCTGCGA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 873; Mature: 873

Protein sequence:

>873_residues
MLSIAKRVFWPYSSRAKGASVHKIVKSINALEGEMAALSSEALFGKTGEFRKMLSEGTVTLDDLLVPAFAVVREASRRVL
DMRHFDVQLIGGIALHRGMIAEMKTGEGKTLVATLAAYLNALESKGVHVVTVNDYLAERDSEWMGKLYSALGISVGCITS
SSSDEARKAAYNCDILYSTNNELGFDYLRDNMKFSRENMVQRGYNYAIVDEVDSILIDESRTPLIISGPVERDSSLYGKV
DALVRDLEQEDYDIDEKSKTAFLTEDGALKVEQLLISHQLIPEGSSLYSAENIIMMHYVGQALRAHKLYFADKDYIVKNG
SVVIIDEFTGRMMDGRRYSDGLHQALEAKEGVRINNENQTLASTTFQNYFRMYKRLSGMTGTAETEADEFLGTYNLQVMQ
IPTNVPVQRVDLDDDIYCTEEEKYEAVIDFIIECHKRKQPTLVGTISIEKSELLSKLLTMRGIKHSVLNARYHEKEAYII
AQAGKPGAVTIATNMAGRGTDIKLGGNPEMLARNELAGITDEEERAKRINKIIEQAKHDKEIVMQAGGLCIIGTERHESR
RIDNQLRGRSGRQGDPGLSKFFLSLEDGLLRIFGSDKVRGMLKRLGMKRGEAIQHKWINRAIERAQKKVEARNYDIRKSL
LRFDDVINEQRKVIFAQRNQILDRETYDLVPFYSNLNCDIVSRIIKEKYCDLGHRETAEELSAEVTRIYGIELDIGALSA
LETREEVIAYLDKVADDLLKKKADGFVHKDENLWDFAARRVLITSLDHLWTDHLAALDSLKCGINLRSVGQKDPLNEFKI
EAFYLLEKMLSRFYEMVIQKLAHIELEVQQQPDDGMINLNNSTSQLFGGIARNDRCPCGSGKKFKHCHGMIKV

Sequences:

>Translated_873_residues
MLSIAKRVFWPYSSRAKGASVHKIVKSINALEGEMAALSSEALFGKTGEFRKMLSEGTVTLDDLLVPAFAVVREASRRVL
DMRHFDVQLIGGIALHRGMIAEMKTGEGKTLVATLAAYLNALESKGVHVVTVNDYLAERDSEWMGKLYSALGISVGCITS
SSSDEARKAAYNCDILYSTNNELGFDYLRDNMKFSRENMVQRGYNYAIVDEVDSILIDESRTPLIISGPVERDSSLYGKV
DALVRDLEQEDYDIDEKSKTAFLTEDGALKVEQLLISHQLIPEGSSLYSAENIIMMHYVGQALRAHKLYFADKDYIVKNG
SVVIIDEFTGRMMDGRRYSDGLHQALEAKEGVRINNENQTLASTTFQNYFRMYKRLSGMTGTAETEADEFLGTYNLQVMQ
IPTNVPVQRVDLDDDIYCTEEEKYEAVIDFIIECHKRKQPTLVGTISIEKSELLSKLLTMRGIKHSVLNARYHEKEAYII
AQAGKPGAVTIATNMAGRGTDIKLGGNPEMLARNELAGITDEEERAKRINKIIEQAKHDKEIVMQAGGLCIIGTERHESR
RIDNQLRGRSGRQGDPGLSKFFLSLEDGLLRIFGSDKVRGMLKRLGMKRGEAIQHKWINRAIERAQKKVEARNYDIRKSL
LRFDDVINEQRKVIFAQRNQILDRETYDLVPFYSNLNCDIVSRIIKEKYCDLGHRETAEELSAEVTRIYGIELDIGALSA
LETREEVIAYLDKVADDLLKKKADGFVHKDENLWDFAARRVLITSLDHLWTDHLAALDSLKCGINLRSVGQKDPLNEFKI
EAFYLLEKMLSRFYEMVIQKLAHIELEVQQQPDDGMINLNNSTSQLFGGIARNDRCPCGSGKKFKHCHGMIKV
>Mature_873_residues
MLSIAKRVFWPYSSRAKGASVHKIVKSINALEGEMAALSSEALFGKTGEFRKMLSEGTVTLDDLLVPAFAVVREASRRVL
DMRHFDVQLIGGIALHRGMIAEMKTGEGKTLVATLAAYLNALESKGVHVVTVNDYLAERDSEWMGKLYSALGISVGCITS
SSSDEARKAAYNCDILYSTNNELGFDYLRDNMKFSRENMVQRGYNYAIVDEVDSILIDESRTPLIISGPVERDSSLYGKV
DALVRDLEQEDYDIDEKSKTAFLTEDGALKVEQLLISHQLIPEGSSLYSAENIIMMHYVGQALRAHKLYFADKDYIVKNG
SVVIIDEFTGRMMDGRRYSDGLHQALEAKEGVRINNENQTLASTTFQNYFRMYKRLSGMTGTAETEADEFLGTYNLQVMQ
IPTNVPVQRVDLDDDIYCTEEEKYEAVIDFIIECHKRKQPTLVGTISIEKSELLSKLLTMRGIKHSVLNARYHEKEAYII
AQAGKPGAVTIATNMAGRGTDIKLGGNPEMLARNELAGITDEEERAKRINKIIEQAKHDKEIVMQAGGLCIIGTERHESR
RIDNQLRGRSGRQGDPGLSKFFLSLEDGLLRIFGSDKVRGMLKRLGMKRGEAIQHKWINRAIERAQKKVEARNYDIRKSL
LRFDDVINEQRKVIFAQRNQILDRETYDLVPFYSNLNCDIVSRIIKEKYCDLGHRETAEELSAEVTRIYGIELDIGALSA
LETREEVIAYLDKVADDLLKKKADGFVHKDENLWDFAARRVLITSLDHLWTDHLAALDSLKCGINLRSVGQKDPLNEFKI
EAFYLLEKMLSRFYEMVIQKLAHIELEVQQQPDDGMINLNNSTSQLFGGIARNDRCPCGSGKKFKHCHGMIKV

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=895, Percent_Identity=50.9497206703911, Blast_Score=836, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_ANAPZ (Q2GIT5)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505716.1
- ProteinModelPortal:   Q2GIT5
- SMR:   Q2GIT5
- STRING:   Q2GIT5
- GeneID:   3930719
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_1178
- NMPDR:   fig|212042.5.peg.1130
- TIGR:   APH_1178
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   SANIREQ
- PhylomeDB:   Q2GIT5
- ProtClustDB:   PRK12904
- BioCyc:   APHA212042:APH_1178-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR014001
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00487
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 98577; Mature: 98577

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIAKRVFWPYSSRAKGASVHKIVKSINALEGEMAALSSEALFGKTGEFRKMLSEGTVT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEE
LDDLLVPAFAVVREASRRVLDMRHFDVQLIGGIALHRGMIAEMKTGEGKTLVATLAAYLN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHH
ALESKGVHVVTVNDYLAERDSEWMGKLYSALGISVGCITSSSSDEARKAAYNCDILYSTN
HHHHCCEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCEEEEECC
NELGFDYLRDNMKFSRENMVQRGYNYAIVDEVDSILIDESRTPLIISGPVERDSSLYGKV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
DALVRDLEQEDYDIDEKSKTAFLTEDGALKVEQLLISHQLIPEGSSLYSAENIIMMHYVG
HHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHH
QALRAHKLYFADKDYIVKNGSVVIIDEFTGRMMDGRRYSDGLHQALEAKEGVRINNENQT
HHHHHHHEEECCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCH
LASTTFQNYFRMYKRLSGMTGTAETEADEFLGTYNLQVMQIPTNVPVQRVDLDDDIYCTE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEECEEEEEECCCCCEEEECCCCCEEECC
EEKYEAVIDFIIECHKRKQPTLVGTISIEKSELLSKLLTMRGIKHSVLNARYHEKEAYII
CHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEE
AQAGKPGAVTIATNMAGRGTDIKLGGNPEMLARNELAGITDEEERAKRINKIIEQAKHDK
EECCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
EIVMQAGGLCIIGTERHESRRIDNQLRGRSGRQGDPGLSKFFLSLEDGLLRIFGSDKVRG
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHH
MLKRLGMKRGEAIQHKWINRAIERAQKKVEARNYDIRKSLLRFDDVINEQRKVIFAQRNQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDRETYDLVPFYSNLNCDIVSRIIKEKYCDLGHRETAEELSAEVTRIYGIELDIGALSA
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECHHHHHH
LETREEVIAYLDKVADDLLKKKADGFVHKDENLWDFAARRVLITSLDHLWTDHLAALDSL
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCGINLRSVGQKDPLNEFKIEAFYLLEKMLSRFYEMVIQKLAHIELEVQQQPDDGMINLN
HCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEC
NSTSQLFGGIARNDRCPCGSGKKFKHCHGMIKV
CCHHHHHCCHHCCCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MLSIAKRVFWPYSSRAKGASVHKIVKSINALEGEMAALSSEALFGKTGEFRKMLSEGTVT
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEE
LDDLLVPAFAVVREASRRVLDMRHFDVQLIGGIALHRGMIAEMKTGEGKTLVATLAAYLN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHH
ALESKGVHVVTVNDYLAERDSEWMGKLYSALGISVGCITSSSSDEARKAAYNCDILYSTN
HHHHCCEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCEEEEECC
NELGFDYLRDNMKFSRENMVQRGYNYAIVDEVDSILIDESRTPLIISGPVERDSSLYGKV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
DALVRDLEQEDYDIDEKSKTAFLTEDGALKVEQLLISHQLIPEGSSLYSAENIIMMHYVG
HHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHH
QALRAHKLYFADKDYIVKNGSVVIIDEFTGRMMDGRRYSDGLHQALEAKEGVRINNENQT
HHHHHHHEEECCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCH
LASTTFQNYFRMYKRLSGMTGTAETEADEFLGTYNLQVMQIPTNVPVQRVDLDDDIYCTE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEECEEEEEECCCCCEEEECCCCCEEECC
EEKYEAVIDFIIECHKRKQPTLVGTISIEKSELLSKLLTMRGIKHSVLNARYHEKEAYII
CHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEE
AQAGKPGAVTIATNMAGRGTDIKLGGNPEMLARNELAGITDEEERAKRINKIIEQAKHDK
EECCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
EIVMQAGGLCIIGTERHESRRIDNQLRGRSGRQGDPGLSKFFLSLEDGLLRIFGSDKVRG
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCHHHHH
MLKRLGMKRGEAIQHKWINRAIERAQKKVEARNYDIRKSLLRFDDVINEQRKVIFAQRNQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDRETYDLVPFYSNLNCDIVSRIIKEKYCDLGHRETAEELSAEVTRIYGIELDIGALSA
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECHHHHHH
LETREEVIAYLDKVADDLLKKKADGFVHKDENLWDFAARRVLITSLDHLWTDHLAALDSL
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCGINLRSVGQKDPLNEFKIEAFYLLEKMLSRFYEMVIQKLAHIELEVQQQPDDGMINLN
HCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEC
NSTSQLFGGIARNDRCPCGSGKKFKHCHGMIKV
CCHHHHHCCHHCCCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA