Click here to switch to the map view.

The map label for this gene is trx [H]

Identifier: 88607814

GI number: 88607814

Start: 86047

End: 86379

Strand: Reverse

Name: trx [H]

Synonym: APH_0080

Alternate gene names: 88607814

Gene position: 86379-86047 (Counterclockwise)

Preceding gene: 88607651

Following gene: 88607239

Centisome position: 5.87

GC content: 45.05

Gene sequence:

>333_bases
ATGGCTCATGTGACTGAGATTGGTGATTCTGATTTCGCTGACAAGGTTGAGCGGAAGAGCGGTATAGTGGTTGTTGACTT
TTGGGCACCGTGGTGTGGCCCTTGCGTCGCGTTTGCTCCACAACTTGACAAAATTGCAGAGCGCTACTCTGGCAAGATAG
ATGTTTATAAGCTCAATGTACAAGATCATCAAGAGACACCCATAAAATTTGGTGTCAGTGCCGTACCAACATTGATTGTT
TTCAAAAATGGCGTTGAATCAGCCCGTATAGTAGGCGTAAATCTGCAGCAGTTACTGAGTGCTATTGATGGTGCTATAGG
TAGCCAGAATTAG

Upstream 100 bases:

>100_bases
TCTACGGTACGGCTCTAGCACAGCTTGTATATTCAATGAGAAAAGGGCATTCCCTGTAGTGAAGGGTGCTGAAAGACGCC
GGAAATAAATTGGAGGTTTT

Downstream 100 bases:

>100_bases
TCTGAGAGAGGAGCTAGTTGTATTCGCGCGCGGCGGAAGTCTGATTTTTGTGTTTAAGTGGTGCTGTCATACACAGAGTT
TAGGTGCGGTTCTTTGTGCA

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MAHVTEIGDSDFADKVERKSGIVVVDFWAPWCGPCVAFAPQLDKIAERYSGKIDVYKLNVQDHQETPIKFGVSAVPTLIV
FKNGVESARIVGVNLQQLLSAIDGAIGSQN

Sequences:

>Translated_110_residues
MAHVTEIGDSDFADKVERKSGIVVVDFWAPWCGPCVAFAPQLDKIAERYSGKIDVYKLNVQDHQETPIKFGVSAVPTLIV
FKNGVESARIVGVNLQQLLSAIDGAIGSQN
>Mature_109_residues
AHVTEIGDSDFADKVERKSGIVVVDFWAPWCGPCVAFAPQLDKIAERYSGKIDVYKLNVQDHQETPIKFGVSAVPTLIVF
KNGVESARIVGVNLQQLLSAIDGAIGSQN

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=91, Percent_Identity=40.6593406593407, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI21361657, Length=87, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=4e-12,
Organism=Homo sapiens, GI24308127, Length=74, Percent_Identity=37.8378378378378, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082331, Length=102, Percent_Identity=42.156862745098, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1788936, Length=71, Percent_Identity=45.0704225352113, Blast_Score=81, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI212646193, Length=83, Percent_Identity=42.1686746987952, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71998175, Length=96, Percent_Identity=40.625, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=99, Percent_Identity=42.4242424242424, Blast_Score=81, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321648, Length=93, Percent_Identity=41.9354838709677, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639826, Length=89, Percent_Identity=34.8314606741573, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24664269, Length=85, Percent_Identity=32.9411764705882, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573567, Length=89, Percent_Identity=34.8314606741573, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17648013, Length=98, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583090, Length=98, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11930; Mature: 11799

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVTEIGDSDFADKVERKSGIVVVDFWAPWCGPCVAFAPQLDKIAERYSGKIDVYKLNV
CCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHCCCEEEEEECC
QDHQETPIKFGVSAVPTLIVFKNGVESARIVGVNLQQLLSAIDGAIGSQN
CCCCCCCEEECHHHHCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AHVTEIGDSDFADKVERKSGIVVVDFWAPWCGPCVAFAPQLDKIAERYSGKIDVYKLNV
CCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHCCCEEEEEECC
QDHQETPIKFGVSAVPTLIVFKNGVESARIVGVNLQQLLSAIDGAIGSQN
CCCCCCCEEECHHHHCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA