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The map label for this gene is coq7 [H]

Identifier: 88607535

GI number: 88607535

Start: 974125

End: 974619

Strand: Reverse

Name: coq7 [H]

Synonym: APH_0911

Alternate gene names: 88607535

Gene position: 974619-974125 (Counterclockwise)

Preceding gene: 88606936

Following gene: 88607949

Centisome position: 66.24

GC content: 45.25

Gene sequence:

>495_bases
ATGATAAGAGTCAATCATGCTGGGGAGTATGCAGCGGTGTGCATATATCATGGGCAAGAAATGGCTCTTAGGGGAAAGGC
AGAAGCGGAGAGTATACGAGAGATGCAACAACATGAACTGGTGCATTTTCGTTACTTCGATAACGCTATAAAAGAAAGAA
GAGTAAGGCCAACAGTGTTTTTACCAATATGGCATGTCGCAGCTGTATCATTAGGATACATTGCAGCTATGATGGGCAAG
GAAGCGGCTATGGCTTGTACTGAAGCTGTTGAAGAGGTAATATGTGGGCATTACTATGAACAAGCAGGGCAGCTAGAGCG
TAGTGATAGCGAGCATGAATTGAGGGATGCAATAGTGCGATTCCGTGAAGAAGAGTGTGAGCATATGGAGATAGCGGCGC
ATAACGGTGCAGAGCGTGCGTTGGGATATAAGGCCATTTCTTGCGCAGTAAAGACTGCTTGTAGGTTGGCAATAGCAATT
TCCAAGGTGTTATAA

Upstream 100 bases:

>100_bases
TGCATTCTAAACTTGGGGAAGGGTATAAAATGGTCTGTAGCTGCTTTTATGTGCTAGCAATATATGGTGCACTGCTATGA
GAAAAGAATGCGTTGAAAGT

Downstream 100 bases:

>100_bases
GTTTTGCTATAGCCCGAGTTTTTATTGGGAAAAATTAAGTACGCGAGTTTTTATGTATAGTTCTAGCAGTGTAGTCAGGT
TATTGACTGACAATTTTATT

Product: Coq7 family protein

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAIKERRVRPTVFLPIWHVAAVSLGYIAAMMGK
EAAMACTEAVEEVICGHYYEQAGQLERSDSEHELRDAIVRFREEECEHMEIAAHNGAERALGYKAISCAVKTACRLAIAI
SKVL

Sequences:

>Translated_164_residues
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAIKERRVRPTVFLPIWHVAAVSLGYIAAMMGK
EAAMACTEAVEEVICGHYYEQAGQLERSDSEHELRDAIVRFREEECEHMEIAAHNGAERALGYKAISCAVKTACRLAIAI
SKVL
>Mature_164_residues
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAIKERRVRPTVFLPIWHVAAVSLGYIAAMMGK
EAAMACTEAVEEVICGHYYEQAGQLERSDSEHELRDAIVRFREEECEHMEIAAHNGAERALGYKAISCAVKTACRLAIAI
SKVL

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI300244542, Length=166, Percent_Identity=42.1686746987952, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI25453484, Length=166, Percent_Identity=42.1686746987952, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552756, Length=164, Percent_Identity=39.0243902439024, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324699, Length=173, Percent_Identity=38.728323699422, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24640215, Length=164, Percent_Identity=45.7317073170732, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: NA

Molecular weight: Translated: 18493; Mature: 18493

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAIKERRVRPTVF
CEEECCCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LPIWHVAAVSLGYIAAMMGKEAAMACTEAVEEVICGHYYEQAGQLERSDSEHELRDAIVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FREEECEHMEIAAHNGAERALGYKAISCAVKTACRLAIAISKVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRVNHAGEYAAVCIYHGQEMALRGKAEAESIREMQQHELVHFRYFDNAIKERRVRPTVF
CEEECCCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LPIWHVAAVSLGYIAAMMGKEAAMACTEAVEEVICGHYYEQAGQLERSDSEHELRDAIVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FREEECEHMEIAAHNGAERALGYKAISCAVKTACRLAIAISKVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]