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The map label for this gene is argD [H]

Identifier: 88607480

GI number: 88607480

Start: 1009136

End: 1010311

Strand: Direct

Name: argD [H]

Synonym: APH_0945

Alternate gene names: 88607480

Gene position: 1009136-1010311 (Clockwise)

Preceding gene: 88607255

Following gene: 88606890

Centisome position: 68.59

GC content: 45.07

Gene sequence:

>1176_bases
GTGGTTTGTGACTTTATGATTCCTTTTTACAAACCGTTCGACATCAGTTTCGTTCGGGGAGAAGGGGTGTACTTGTATGA
TAGTAGCGGGAAGCGTTATATAGACTTCGGTTCTGGAAGGGCTACGAGCGCGCTTGGTCACTGCCATCCAGCTATGGTAC
AGGCATTGTGTGAGCAATCCAAAGCGCTATGGCATGTGTCTAACATGTATAGAATTCAGGAATCTGAAAGCTTGGCTGCA
GAACTTGTAGGCTTAAGTTTCGCCGATATGGCATTTTTTGTGAATTCTGGCGCAGAAGCTGTTGAGTGCGGATTTAAGGT
TGCTCGGTCATACCAAAATGGTATAGGACGTCCTGAAAGGTATAAAGTACTGACGTTGAGGCGTGCGTTCCATGGAAGAA
CTTATGCAACGTGCTCTGCTAGTGAGCCGACAGGTTTTCTTCCCCTTTTATACCCGTATGTCGATTGGTTTGTGAGTGTT
ACTCCATCCATAGAGGCTATACGTAGTGAGGTAGAAAAAGGAAACATAGGTGCCATACTAGTAGAACCAGTGCAGGGCGA
AGGTGGCATTCATGTGCTGAGCGGTGAACTGTTGAGAGATTTGCGAGCATTGTGTGATCAACACGACATATTGCTATTCT
TTGACTGTGTACAATGTGGCTCCGGGAGGACAGGAAAATTCTTTGCTTATGAGCATTTTTCCGTAACACCAGACATATGC
TCGCTTGCAAAGGGTTTAGGGGGTGGGTTCCCTATAGGTGGATGCCTCATAACGAAAAAAGCAGGGCAATTTGTTACTGA
GCGCATGCATGGCTCGACTTGTGGTGGTAATCCTTTGGCTACTGCTGTTGCTCGCGCGATCGTTCGTGAAATAACCAAGC
CAGGCTTTTTGGCAAACGTAGAACAAAATGGTGCTTATTTCATCGAGCAGCTGAGTCAAATGGCTACGAGGTTTCCTATA
ATAAAGAATGTTAGAGGAATAGGCCTCTTGATCGGTGTAGAAATTAATGATACAGCAAGTGCTCACAGCATGGCTGAACA
ACTTATATCCCATGGTATACTGATTGCCCCAGCATCTGGGAATGTGTTGAGAATGGTTCCTCCATTAATTGTCTCAAGAC
AAGAGATAGATGAGTTTTTGCAGATATTTGAAGGCTTTCTGCGTTCGTTTAGTTAG

Upstream 100 bases:

>100_bases
ATCCTTAATGATCATTTGGCTTCCAAGGTACTTTTCTGTTGACCTATTTGAAATAGAGGAGTTATCCTGAGCGTTGACCA
GTCAGTATTATGGGATAGTT

Downstream 100 bases:

>100_bases
TGAGACTCGGGCTGCATGCTTGTGGTTGTGATGTAAGGGATGCGCTAGGTTGCTCTGCACAATAGGTGGGCTTAGGGTAG
ATGTATACTGACGTTACGCA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MVCDFMIPFYKPFDISFVRGEGVYLYDSSGKRYIDFGSGRATSALGHCHPAMVQALCEQSKALWHVSNMYRIQESESLAA
ELVGLSFADMAFFVNSGAEAVECGFKVARSYQNGIGRPERYKVLTLRRAFHGRTYATCSASEPTGFLPLLYPYVDWFVSV
TPSIEAIRSEVEKGNIGAILVEPVQGEGGIHVLSGELLRDLRALCDQHDILLFFDCVQCGSGRTGKFFAYEHFSVTPDIC
SLAKGLGGGFPIGGCLITKKAGQFVTERMHGSTCGGNPLATAVARAIVREITKPGFLANVEQNGAYFIEQLSQMATRFPI
IKNVRGIGLLIGVEINDTASAHSMAEQLISHGILIAPASGNVLRMVPPLIVSRQEIDEFLQIFEGFLRSFS

Sequences:

>Translated_391_residues
MVCDFMIPFYKPFDISFVRGEGVYLYDSSGKRYIDFGSGRATSALGHCHPAMVQALCEQSKALWHVSNMYRIQESESLAA
ELVGLSFADMAFFVNSGAEAVECGFKVARSYQNGIGRPERYKVLTLRRAFHGRTYATCSASEPTGFLPLLYPYVDWFVSV
TPSIEAIRSEVEKGNIGAILVEPVQGEGGIHVLSGELLRDLRALCDQHDILLFFDCVQCGSGRTGKFFAYEHFSVTPDIC
SLAKGLGGGFPIGGCLITKKAGQFVTERMHGSTCGGNPLATAVARAIVREITKPGFLANVEQNGAYFIEQLSQMATRFPI
IKNVRGIGLLIGVEINDTASAHSMAEQLISHGILIAPASGNVLRMVPPLIVSRQEIDEFLQIFEGFLRSFS
>Mature_391_residues
MVCDFMIPFYKPFDISFVRGEGVYLYDSSGKRYIDFGSGRATSALGHCHPAMVQALCEQSKALWHVSNMYRIQESESLAA
ELVGLSFADMAFFVNSGAEAVECGFKVARSYQNGIGRPERYKVLTLRRAFHGRTYATCSASEPTGFLPLLYPYVDWFVSV
TPSIEAIRSEVEKGNIGAILVEPVQGEGGIHVLSGELLRDLRALCDQHDILLFFDCVQCGSGRTGKFFAYEHFSVTPDIC
SLAKGLGGGFPIGGCLITKKAGQFVTERMHGSTCGGNPLATAVARAIVREITKPGFLANVEQNGAYFIEQLSQMATRFPI
IKNVRGIGLLIGVEINDTASAHSMAEQLISHGILIAPASGNVLRMVPPLIVSRQEIDEFLQIFEGFLRSFS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=395, Percent_Identity=31.1392405063291, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI13994255, Length=432, Percent_Identity=26.8518518518519, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI284507298, Length=311, Percent_Identity=31.5112540192926, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=427, Percent_Identity=26.463700234192, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=27.7777777777778, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=26.3427109974425, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI188536080, Length=433, Percent_Identity=22.4018475750577, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38679950, Length=433, Percent_Identity=22.4018475750577, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38679946, Length=433, Percent_Identity=22.4018475750577, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=25.4672897196262, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1788044, Length=390, Percent_Identity=39.7435897435897, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=39.386189258312, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=35.0877192982456, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI145693181, Length=370, Percent_Identity=32.7027027027027, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789016, Length=395, Percent_Identity=30.8860759493671, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786991, Length=394, Percent_Identity=29.9492385786802, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786349, Length=338, Percent_Identity=28.9940828402367, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=29.5336787564767, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=28.5388127853881, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=31.0606060606061, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=24.8837209302326, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=431, Percent_Identity=21.5777262180974, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=156, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=33.248730964467, Blast_Score=216, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=390, Percent_Identity=32.5641025641026, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324386, Length=356, Percent_Identity=24.438202247191, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=22.8235294117647, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=31.4432989690722, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=30.8755760368664, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=31.042654028436, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=28.9855072463768, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281366494, Length=433, Percent_Identity=24.9422632794457, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24667139, Length=433, Percent_Identity=24.9422632794457, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24667143, Length=433, Percent_Identity=24.9422632794457, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42695; Mature: 42695

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00783 RIBOSOMAL_L13

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCDFMIPFYKPFDISFVRGEGVYLYDSSGKRYIDFGSGRATSALGHCHPAMVQALCEQS
CCCCCCCCCCCCCCEEEEECCEEEEECCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHH
KALWHVSNMYRIQESESLAAELVGLSFADMAFFVNSGAEAVECGFKVARSYQNGIGRPER
HHHEEHHHHHHEHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
YKVLTLRRAFHGRTYATCSASEPTGFLPLLYPYVDWFVSVTPSIEAIRSEVEKGNIGAIL
EEHEEEHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEE
VEPVQGEGGIHVLSGELLRDLRALCDQHDILLFFDCVQCGSGRTGKFFAYEHFSVTPDIC
EEECCCCCCEEEECHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEECCCCCHHHH
SLAKGLGGGFPIGGCLITKKAGQFVTERMHGSTCGGNPLATAVARAIVREITKPGFLANV
HHHHHCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
EQNGAYFIEQLSQMATRFPIIKNVRGIGLLIGVEINDTASAHSMAEQLISHGILIAPASG
CCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCC
NVLRMVPPLIVSRQEIDEFLQIFEGFLRSFS
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVCDFMIPFYKPFDISFVRGEGVYLYDSSGKRYIDFGSGRATSALGHCHPAMVQALCEQS
CCCCCCCCCCCCCCEEEEECCEEEEECCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHH
KALWHVSNMYRIQESESLAAELVGLSFADMAFFVNSGAEAVECGFKVARSYQNGIGRPER
HHHEEHHHHHHEHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
YKVLTLRRAFHGRTYATCSASEPTGFLPLLYPYVDWFVSVTPSIEAIRSEVEKGNIGAIL
EEHEEEHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEE
VEPVQGEGGIHVLSGELLRDLRALCDQHDILLFFDCVQCGSGRTGKFFAYEHFSVTPDIC
EEECCCCCCEEEECHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEECCCCCHHHH
SLAKGLGGGFPIGGCLITKKAGQFVTERMHGSTCGGNPLATAVARAIVREITKPGFLANV
HHHHHCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
EQNGAYFIEQLSQMATRFPIIKNVRGIGLLIGVEINDTASAHSMAEQLISHGILIAPASG
CCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCC
NVLRMVPPLIVSRQEIDEFLQIFEGFLRSFS
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]