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The map label for this gene is putA [H]

Identifier: 88607442

GI number: 88607442

Start: 688365

End: 691502

Strand: Direct

Name: putA [H]

Synonym: APH_0669

Alternate gene names: 88607442

Gene position: 688365-691502 (Clockwise)

Preceding gene: 88607668

Following gene: 88607784

Centisome position: 46.79

GC content: 43.47

Gene sequence:

>3138_bases
ATGATGATAAGTTCATTGCAGGTGCCCGATGAGTTACGTAAGCGTATGCAGGGGCTGTATAATACTGATGAGAAGAGTTA
TATCAGATATTTAACAGAGAAGGCCGAGGTCTCTCAGGACGCCAAAGTAAGAATATATAACCTTGCTAAGCAGATAATTG
AAAAGGTGCGTTTTGGAAAGGGCTCTACGCTCATAGATGCCTTCATGCAGGAGTATGGTCTTTCTAGCGAGGAGGGAGTT
GCTTTGATGTGTTTGGCGGAATCTTTGTTGAGGATTCCGGATGAATGCACCATCGATGAGATGATTAGAGATAAGATAGC
AGGTACGACTTGGAAAAAGCATATAGGGAGTTCTTCTTCGATATTCGTCAATGCGTCTACCTTGGCGTTGTGTGTAGGCG
CGCGTGTGCTAAGAGAGGTGGATGATTCTCGGTGGTATAGTGTACTAAGTAATCTCCTGAAAAATATGGGAGAGCCCATA
ATAAGGAAAGCTGCTCTCCAGGCTATGTGTATTCTCGGTAAGCATTTTGTCATGGGGCGTGACATAGAAGATGCTGTTGC
AAGGAGTAACGATTCAAAGCAGTTATGTTCGTTTGATATTTTGGGTGAGTCTGCAAGAACTAGGGAAGATGCGGACAGGT
ATTTTGCGGCATACATGCACGCTATAGAGGTAATAGGAGCAGATGCGGGATGCGGTGATGATATTTCCTCTAGACATGGA
ATATCGGTTAAGCTTTCTGCTTTGCATCCGCGTTATGATTTTGCTCAAATCGACTACGTTCTTGATGATATATCTTCTAA
GCTATTGGAGATATGTGCTGCGGCGAAGAAGCATAATATAGGGGTGCTAATTGATGCGGAAGAGGCTCGGAGGTTAGAGG
CTTCTTTGATAGTTTTGGAGAAGGTGTTTTTAGATAAGTCGCTAGATGGCTGGGAAGGGCTGGGGCTCGCGGTTCAAGCG
TATCAAAAGAGAGCCTTAGGTGTGCTGGATATCGTGGAAGATATAGCGATTAGGGCTAACCGTAAGATGGTTGTGAGGCT
AGTTAAGGGTGCTTACTGGGATTATGAGATTAAGAATGCTCAGGAGCTTGGCTTGGACGGGTATCCGGTGTTTACAAGAA
GAGCTTATACTGACACATCTTACTTTGCATGTGTTCAAAGAATTTTGAGTAAGCCAAATACTTTCTATCCGTGCTTTGCT
ACTCACAATGCGTATACTTTGGCTTCGGTATTAGAATCAGCGGATAAGGATCACCCGGGTTTTGAATTTCAGAGGCTGCA
TGCTATGGGGCAGGGTCTATACAGTTATGTTACAGGTGAAGTTGCTCCGAGTGTGAAGTGTAGGGTATATGCTCCAGTTG
GAAGTTATCAAGACTTATTGCCGTATCTTATCAGGAGGCTATTGGAAAATGGTACCAATAGTTCTTTTGTGAATAAGATA
AATGATGTTGATGTTCTAGCTGAACAGCTTTTGGTCGATCCTTTAGAGAAGGCTAAGAGTTTTGAGTATTGTCCGCATCC
TAGTATTCCTTTGCCGATAGATATGTTTGGAAAGGATCGTGTAAATTCCATTGGTCTCAATACTTCTGATTCATTGGCTA
TGTCTGTGCTTAATGAGGAAGTGCAGACATTTACAAATGTCACTCGTAAGGCTACTCCTATCATTAATGGGGAGGATGTA
GAGGGTGCTGCTCCTATAGAGTTTTTCTCTCCGGGAGATTTTAGCTGCAAGGTAGGGGAAGTATCTTATGCAACTCCTGA
GCAGGTGAAGGAAGCTTTTGCTGTTGCGCATGCTGCGTATGCAGAGTGGAGCGCTTTATCAGTTGAAGAACGTGCTACTA
TCTTGGAGTCTGCTGCAGACTTACTAGAAAAAGAAAGGGGTAAGTTTGTTGCTTTGCTAATGCTGGAAGGCGGTAAGGTG
ATTTCTGATGTAATGGCAGAGATTAGAGAAGCTGTAGACTTTTTGAGATACTATGCGATGATAGCTAGGAAGGATATAGC
TGGTACGATTAAGCTTCCTGGGCCTTCGGGTGAAGAGAATTACATATACTTCGAGAGTAGGGGTGTCTTTGTATGTATTT
CTCCTTGGAATTTCCCATTGGCAATATTTTTAGGGCCTATAGCAGCTGCTTTAGTTACTGGTAATACGGTTATAGCTAAG
CCATCTGAGCAGACTTCTCTGATTGCTTATGAAGCTGTGAAATTATTTTTCAGAGCTGGTCTTCCGGGTAGTGTTTTGCA
ATTCTTGCCTGGTGAAGGCGCTGCTTTAGGAGAAGTGCTTATAAATAATGGGCACGTTGCAGGTGTGGCATTTACGGGTT
CTACTGATACTGCGAATATAATAAATAGAACGCTAGCTAAGCGTAATAGGGACATAGTGCCTATTATTGCGGAAACGGGC
GGGATAAACGCGATGATTGTCGATAGTTCTGCTGTGCTTGAGCAAGTTTGCGATGATGTAATAACTTCTGCATTTAGAAG
TGCTGGTCAGAGGTGTTCGGCTTTGAGAGTGCTTTTATTGCAGGAAGAGATTGCTGATAGGCAAATCGAGATCATATGTG
GGGCGCTGAAGGAGTTAAGGCTGGGTAATCCGATGTTGCTAAGTAGTGATGTTGGTCCTGTGATAGATCAGCAGTCTTAT
GACATGCTTTGTGAATATGTGAAAGGCATGGAAGAGAAGGGGGCTAAGCTGTTATGTAAGCTAGATATAGGTTCTCTTGC
GGAAGTAGGGCATTATTTCCCGCCGCATATTTTCGAGGTGGGGTCAGTATCTGAGGTTGCTAAAGAGGTGTTCGGTCCTA
TACTGCACATTGTGAGATATAAGAAGTCTGATCTGGTTAGTATCTTGGAGGAAATAAATAAGACAGGATATGGTCTGACG
TTCTCTGTGCAAAGTCGGATACAGAGTAATATCGATTTGATTGTCGATAAGATTAGAACTGGTAATGTTTACGTCAACAG
GAATCAAATAGGTGCTGTTGTGGGTGTGCAACCATTTGGTGGTTCTGGTCTTTCGGGAACTGGGCCAAAGGCAGGTGGGC
CTTTCTACTTGCATAGGTTTGTTACTGAGAAGACTGTAACAGTAAATACTACGGCGCTTGGCGGTAATGTTGCTCTTGCA
TGCCTTGAAGAAGAGTAA

Upstream 100 bases:

>100_bases
TAAATCTTTATCTTTATGGAGCCGTACTTTTATTTTGGTAAGCGGGCTGTAGACGTAGGAAGTTCGCGTTGCTGTTGATG
TTTTTGGGAGATGATAATAC

Downstream 100 bases:

>100_bases
AAGAAAACTTGGAGGAAGCGTAGTCTAACCTTTAAGGGGTATGCTGCGCTTTTTCTGAGCTTTTCTATTTTGCGAATTAT
TGAAGTGGGCCTGTTTTTTA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1045; Mature: 1045

Protein sequence:

>1045_residues
MMISSLQVPDELRKRMQGLYNTDEKSYIRYLTEKAEVSQDAKVRIYNLAKQIIEKVRFGKGSTLIDAFMQEYGLSSEEGV
ALMCLAESLLRIPDECTIDEMIRDKIAGTTWKKHIGSSSSIFVNASTLALCVGARVLREVDDSRWYSVLSNLLKNMGEPI
IRKAALQAMCILGKHFVMGRDIEDAVARSNDSKQLCSFDILGESARTREDADRYFAAYMHAIEVIGADAGCGDDISSRHG
ISVKLSALHPRYDFAQIDYVLDDISSKLLEICAAAKKHNIGVLIDAEEARRLEASLIVLEKVFLDKSLDGWEGLGLAVQA
YQKRALGVLDIVEDIAIRANRKMVVRLVKGAYWDYEIKNAQELGLDGYPVFTRRAYTDTSYFACVQRILSKPNTFYPCFA
THNAYTLASVLESADKDHPGFEFQRLHAMGQGLYSYVTGEVAPSVKCRVYAPVGSYQDLLPYLIRRLLENGTNSSFVNKI
NDVDVLAEQLLVDPLEKAKSFEYCPHPSIPLPIDMFGKDRVNSIGLNTSDSLAMSVLNEEVQTFTNVTRKATPIINGEDV
EGAAPIEFFSPGDFSCKVGEVSYATPEQVKEAFAVAHAAYAEWSALSVEERATILESAADLLEKERGKFVALLMLEGGKV
ISDVMAEIREAVDFLRYYAMIARKDIAGTIKLPGPSGEENYIYFESRGVFVCISPWNFPLAIFLGPIAAALVTGNTVIAK
PSEQTSLIAYEAVKLFFRAGLPGSVLQFLPGEGAALGEVLINNGHVAGVAFTGSTDTANIINRTLAKRNRDIVPIIAETG
GINAMIVDSSAVLEQVCDDVITSAFRSAGQRCSALRVLLLQEEIADRQIEIICGALKELRLGNPMLLSSDVGPVIDQQSY
DMLCEYVKGMEEKGAKLLCKLDIGSLAEVGHYFPPHIFEVGSVSEVAKEVFGPILHIVRYKKSDLVSILEEINKTGYGLT
FSVQSRIQSNIDLIVDKIRTGNVYVNRNQIGAVVGVQPFGGSGLSGTGPKAGGPFYLHRFVTEKTVTVNTTALGGNVALA
CLEEE

Sequences:

>Translated_1045_residues
MMISSLQVPDELRKRMQGLYNTDEKSYIRYLTEKAEVSQDAKVRIYNLAKQIIEKVRFGKGSTLIDAFMQEYGLSSEEGV
ALMCLAESLLRIPDECTIDEMIRDKIAGTTWKKHIGSSSSIFVNASTLALCVGARVLREVDDSRWYSVLSNLLKNMGEPI
IRKAALQAMCILGKHFVMGRDIEDAVARSNDSKQLCSFDILGESARTREDADRYFAAYMHAIEVIGADAGCGDDISSRHG
ISVKLSALHPRYDFAQIDYVLDDISSKLLEICAAAKKHNIGVLIDAEEARRLEASLIVLEKVFLDKSLDGWEGLGLAVQA
YQKRALGVLDIVEDIAIRANRKMVVRLVKGAYWDYEIKNAQELGLDGYPVFTRRAYTDTSYFACVQRILSKPNTFYPCFA
THNAYTLASVLESADKDHPGFEFQRLHAMGQGLYSYVTGEVAPSVKCRVYAPVGSYQDLLPYLIRRLLENGTNSSFVNKI
NDVDVLAEQLLVDPLEKAKSFEYCPHPSIPLPIDMFGKDRVNSIGLNTSDSLAMSVLNEEVQTFTNVTRKATPIINGEDV
EGAAPIEFFSPGDFSCKVGEVSYATPEQVKEAFAVAHAAYAEWSALSVEERATILESAADLLEKERGKFVALLMLEGGKV
ISDVMAEIREAVDFLRYYAMIARKDIAGTIKLPGPSGEENYIYFESRGVFVCISPWNFPLAIFLGPIAAALVTGNTVIAK
PSEQTSLIAYEAVKLFFRAGLPGSVLQFLPGEGAALGEVLINNGHVAGVAFTGSTDTANIINRTLAKRNRDIVPIIAETG
GINAMIVDSSAVLEQVCDDVITSAFRSAGQRCSALRVLLLQEEIADRQIEIICGALKELRLGNPMLLSSDVGPVIDQQSY
DMLCEYVKGMEEKGAKLLCKLDIGSLAEVGHYFPPHIFEVGSVSEVAKEVFGPILHIVRYKKSDLVSILEEINKTGYGLT
FSVQSRIQSNIDLIVDKIRTGNVYVNRNQIGAVVGVQPFGGSGLSGTGPKAGGPFYLHRFVTEKTVTVNTTALGGNVALA
CLEEE
>Mature_1045_residues
MMISSLQVPDELRKRMQGLYNTDEKSYIRYLTEKAEVSQDAKVRIYNLAKQIIEKVRFGKGSTLIDAFMQEYGLSSEEGV
ALMCLAESLLRIPDECTIDEMIRDKIAGTTWKKHIGSSSSIFVNASTLALCVGARVLREVDDSRWYSVLSNLLKNMGEPI
IRKAALQAMCILGKHFVMGRDIEDAVARSNDSKQLCSFDILGESARTREDADRYFAAYMHAIEVIGADAGCGDDISSRHG
ISVKLSALHPRYDFAQIDYVLDDISSKLLEICAAAKKHNIGVLIDAEEARRLEASLIVLEKVFLDKSLDGWEGLGLAVQA
YQKRALGVLDIVEDIAIRANRKMVVRLVKGAYWDYEIKNAQELGLDGYPVFTRRAYTDTSYFACVQRILSKPNTFYPCFA
THNAYTLASVLESADKDHPGFEFQRLHAMGQGLYSYVTGEVAPSVKCRVYAPVGSYQDLLPYLIRRLLENGTNSSFVNKI
NDVDVLAEQLLVDPLEKAKSFEYCPHPSIPLPIDMFGKDRVNSIGLNTSDSLAMSVLNEEVQTFTNVTRKATPIINGEDV
EGAAPIEFFSPGDFSCKVGEVSYATPEQVKEAFAVAHAAYAEWSALSVEERATILESAADLLEKERGKFVALLMLEGGKV
ISDVMAEIREAVDFLRYYAMIARKDIAGTIKLPGPSGEENYIYFESRGVFVCISPWNFPLAIFLGPIAAALVTGNTVIAK
PSEQTSLIAYEAVKLFFRAGLPGSVLQFLPGEGAALGEVLINNGHVAGVAFTGSTDTANIINRTLAKRNRDIVPIIAETG
GINAMIVDSSAVLEQVCDDVITSAFRSAGQRCSALRVLLLQEEIADRQIEIICGALKELRLGNPMLLSSDVGPVIDQQSY
DMLCEYVKGMEEKGAKLLCKLDIGSLAEVGHYFPPHIFEVGSVSEVAKEVFGPILHIVRYKKSDLVSILEEINKTGYGLT
FSVQSRIQSNIDLIVDKIRTGNVYVNRNQIGAVVGVQPFGGSGLSGTGPKAGGPFYLHRFVTEKTVTVNTTALGGNVALA
CLEEE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=524, Percent_Identity=30.3435114503817, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI21361176, Length=460, Percent_Identity=31.304347826087, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI25777736, Length=544, Percent_Identity=28.4926470588235, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI25777734, Length=544, Percent_Identity=28.4926470588235, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI153266822, Length=459, Percent_Identity=29.6296296296296, Blast_Score=194, Evalue=4e-49,
Organism=Homo sapiens, GI238859541, Length=503, Percent_Identity=29.2246520874751, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI25777724, Length=470, Percent_Identity=30.4255319148936, Blast_Score=192, Evalue=2e-48,
Organism=Homo sapiens, GI25777730, Length=521, Percent_Identity=29.5585412667946, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI21614513, Length=483, Percent_Identity=29.8136645962733, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI25777728, Length=429, Percent_Identity=31.2354312354312, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI115387104, Length=448, Percent_Identity=29.6875, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI238814322, Length=484, Percent_Identity=28.9256198347107, Blast_Score=173, Evalue=7e-43,
Organism=Homo sapiens, GI12007648, Length=490, Percent_Identity=27.9591836734694, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI25777726, Length=470, Percent_Identity=28.0851063829787, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=27.1461716937355, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI25952152, Length=480, Percent_Identity=27.0833333333333, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=26.8018018018018, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI188035924, Length=461, Percent_Identity=26.2472885032538, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128103, Length=444, Percent_Identity=26.5765765765766, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI310128093, Length=443, Percent_Identity=26.410835214447, Blast_Score=126, Evalue=9e-29,
Organism=Homo sapiens, GI310128091, Length=398, Percent_Identity=27.6381909547739, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI11095441, Length=389, Percent_Identity=25.4498714652956, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI206597441, Length=436, Percent_Identity=25.2293577981651, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI206597439, Length=436, Percent_Identity=25.2293577981651, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI22907049, Length=436, Percent_Identity=25.2293577981651, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI4502043, Length=461, Percent_Identity=24.7288503253796, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI238814371, Length=461, Percent_Identity=24.7288503253796, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI73466520, Length=339, Percent_Identity=25.9587020648968, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4557303, Length=339, Percent_Identity=25.9587020648968, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI71773324, Length=360, Percent_Identity=26.1111111111111, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128087, Length=268, Percent_Identity=27.6119402985075, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI301500698, Length=288, Percent_Identity=25.6944444444444, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI73695881, Length=360, Percent_Identity=25.2777777777778, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI73695879, Length=360, Percent_Identity=25.2777777777778, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=26.0606060606061, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128095, Length=311, Percent_Identity=26.0450160771704, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128097, Length=249, Percent_Identity=27.3092369477912, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI310128099, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=7e-12,
Organism=Escherichia coli, GI1787250, Length=1042, Percent_Identity=44.721689059501, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=483, Percent_Identity=31.055900621118, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI87081896, Length=434, Percent_Identity=31.5668202764977, Blast_Score=179, Evalue=7e-46,
Organism=Escherichia coli, GI1787558, Length=487, Percent_Identity=29.9794661190965, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1787684, Length=484, Percent_Identity=28.5123966942149, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788042, Length=439, Percent_Identity=30.2961275626424, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1786504, Length=456, Percent_Identity=28.2894736842105, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1787715, Length=467, Percent_Identity=30.8351177730193, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI87082295, Length=465, Percent_Identity=28.3870967741935, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI87081926, Length=448, Percent_Identity=24.1071428571429, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1787653, Length=364, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=485, Percent_Identity=32.9896907216495, Blast_Score=200, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI133930964, Length=458, Percent_Identity=29.6943231441048, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17562198, Length=486, Percent_Identity=29.4238683127572, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144435, Length=433, Percent_Identity=29.5612009237875, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17551164, Length=456, Percent_Identity=29.6052631578947, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=427, Percent_Identity=31.8501170960187, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564736, Length=428, Percent_Identity=29.4392523364486, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=453, Percent_Identity=29.1390728476821, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=453, Percent_Identity=29.1390728476821, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32564151, Length=416, Percent_Identity=31.7307692307692, Blast_Score=152, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17534119, Length=445, Percent_Identity=29.2134831460674, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=498, Percent_Identity=27.1084337349398, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71995606, Length=448, Percent_Identity=27.4553571428571, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=306, Percent_Identity=34.3137254901961, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=404, Percent_Identity=27.4752475247525, Blast_Score=126, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71986308, Length=441, Percent_Identity=24.4897959183673, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=346, Percent_Identity=26.3005780346821, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17564084, Length=353, Percent_Identity=25.7790368271955, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32566756, Length=346, Percent_Identity=26.3005780346821, Blast_Score=103, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=346, Percent_Identity=26.3005780346821, Blast_Score=103, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321826, Length=524, Percent_Identity=30.1526717557252, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=472, Percent_Identity=29.2372881355932, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324950, Length=434, Percent_Identity=29.4930875576037, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=445, Percent_Identity=30.561797752809, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323821, Length=446, Percent_Identity=31.1659192825112, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6320917, Length=468, Percent_Identity=29.0598290598291, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=461, Percent_Identity=27.9826464208243, Blast_Score=151, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6321828, Length=480, Percent_Identity=27.0833333333333, Blast_Score=127, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323757, Length=330, Percent_Identity=28.1818181818182, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129399, Length=461, Percent_Identity=31.236442516269, Blast_Score=199, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24585660, Length=489, Percent_Identity=28.8343558282209, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24668425, Length=475, Percent_Identity=29.8947368421053, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24668417, Length=475, Percent_Identity=29.8947368421053, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24668413, Length=475, Percent_Identity=29.8947368421053, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281362580, Length=439, Percent_Identity=28.9293849658314, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI62472918, Length=439, Percent_Identity=28.9293849658314, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI62472926, Length=439, Percent_Identity=28.9293849658314, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI62472936, Length=439, Percent_Identity=28.9293849658314, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI21356737, Length=439, Percent_Identity=28.9293849658314, Blast_Score=173, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28571802, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28571800, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28571798, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28571796, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28571794, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI28571806, Length=501, Percent_Identity=26.5469061876248, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24650465, Length=484, Percent_Identity=28.3057851239669, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574525, Length=527, Percent_Identity=24.0986717267552, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24666674, Length=500, Percent_Identity=26.2, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24638878, Length=416, Percent_Identity=24.5192307692308, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24638876, Length=416, Percent_Identity=24.5192307692308, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360299, Length=351, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360297, Length=351, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360295, Length=351, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586250, Length=351, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360301, Length=351, Percent_Identity=25.9259259259259, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45552499, Length=350, Percent_Identity=26, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281360303, Length=350, Percent_Identity=26, Blast_Score=88, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 114582; Mature: 114582

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMISSLQVPDELRKRMQGLYNTDEKSYIRYLTEKAEVSQDAKVRIYNLAKQIIEKVRFGK
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GSTLIDAFMQEYGLSSEEGVALMCLAESLLRIPDECTIDEMIRDKIAGTTWKKHIGSSSS
CCHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCE
IFVNASTLALCVGARVLREVDDSRWYSVLSNLLKNMGEPIIRKAALQAMCILGKHFVMGR
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DIEDAVARSNDSKQLCSFDILGESARTREDADRYFAAYMHAIEVIGADAGCGDDISSRHG
CHHHHHHCCCCCHHHHHHHECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ISVKLSALHPRYDFAQIDYVLDDISSKLLEICAAAKKHNIGVLIDAEEARRLEASLIVLE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
KVFLDKSLDGWEGLGLAVQAYQKRALGVLDIVEDIAIRANRKMVVRLVKGAYWDYEIKNA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCH
QELGLDGYPVFTRRAYTDTSYFACVQRILSKPNTFYPCFATHNAYTLASVLESADKDHPG
HHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
FEFQRLHAMGQGLYSYVTGEVAPSVKCRVYAPVGSYQDLLPYLIRRLLENGTNSSFVNKI
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHH
NDVDVLAEQLLVDPLEKAKSFEYCPHPSIPLPIDMFGKDRVNSIGLNTSDSLAMSVLNEE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VQTFTNVTRKATPIINGEDVEGAAPIEFFSPGDFSCKVGEVSYATPEQVKEAFAVAHAAY
HHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
AEWSALSVEERATILESAADLLEKERGKFVALLMLEGGKVISDVMAEIREAVDFLRYYAM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IARKDIAGTIKLPGPSGEENYIYFESRGVFVCISPWNFPLAIFLGPIAAALVTGNTVIAK
HHHHCCCEEEECCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEC
PSEQTSLIAYEAVKLFFRAGLPGSVLQFLPGEGAALGEVLINNGHVAGVAFTGSTDTANI
CCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHEECCCEEEEEEEECCCCHHHH
INRTLAKRNRDIVPIIAETGGINAMIVDSSAVLEQVCDDVITSAFRSAGQRCSALRVLLL
HHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEIADRQIEIICGALKELRLGNPMLLSSDVGPVIDQQSYDMLCEYVKGMEEKGAKLLCK
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCHHHCCCEEEEE
LDIGSLAEVGHYFPPHIFEVGSVSEVAKEVFGPILHIVRYKKSDLVSILEEINKTGYGLT
ECCCCHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
FSVQSRIQSNIDLIVDKIRTGNVYVNRNQIGAVVGVQPFGGSGLSGTGPKAGGPFYLHRF
EEEHHHHHCCHHHHHHHEECCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
VTEKTVTVNTTALGGNVALACLEEE
HCCCEEEEEEEEECCCEEEEEEECC
>Mature Secondary Structure
MMISSLQVPDELRKRMQGLYNTDEKSYIRYLTEKAEVSQDAKVRIYNLAKQIIEKVRFGK
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GSTLIDAFMQEYGLSSEEGVALMCLAESLLRIPDECTIDEMIRDKIAGTTWKKHIGSSSS
CCHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCE
IFVNASTLALCVGARVLREVDDSRWYSVLSNLLKNMGEPIIRKAALQAMCILGKHFVMGR
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DIEDAVARSNDSKQLCSFDILGESARTREDADRYFAAYMHAIEVIGADAGCGDDISSRHG
CHHHHHHCCCCCHHHHHHHECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ISVKLSALHPRYDFAQIDYVLDDISSKLLEICAAAKKHNIGVLIDAEEARRLEASLIVLE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
KVFLDKSLDGWEGLGLAVQAYQKRALGVLDIVEDIAIRANRKMVVRLVKGAYWDYEIKNA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCH
QELGLDGYPVFTRRAYTDTSYFACVQRILSKPNTFYPCFATHNAYTLASVLESADKDHPG
HHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
FEFQRLHAMGQGLYSYVTGEVAPSVKCRVYAPVGSYQDLLPYLIRRLLENGTNSSFVNKI
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHH
NDVDVLAEQLLVDPLEKAKSFEYCPHPSIPLPIDMFGKDRVNSIGLNTSDSLAMSVLNEE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VQTFTNVTRKATPIINGEDVEGAAPIEFFSPGDFSCKVGEVSYATPEQVKEAFAVAHAAY
HHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
AEWSALSVEERATILESAADLLEKERGKFVALLMLEGGKVISDVMAEIREAVDFLRYYAM
HHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IARKDIAGTIKLPGPSGEENYIYFESRGVFVCISPWNFPLAIFLGPIAAALVTGNTVIAK
HHHHCCCEEEECCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEC
PSEQTSLIAYEAVKLFFRAGLPGSVLQFLPGEGAALGEVLINNGHVAGVAFTGSTDTANI
CCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHEECCCEEEEEEEECCCCHHHH
INRTLAKRNRDIVPIIAETGGINAMIVDSSAVLEQVCDDVITSAFRSAGQRCSALRVLLL
HHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEIADRQIEIICGALKELRLGNPMLLSSDVGPVIDQQSYDMLCEYVKGMEEKGAKLLCK
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCHHHCCCEEEEE
LDIGSLAEVGHYFPPHIFEVGSVSEVAKEVFGPILHIVRYKKSDLVSILEEINKTGYGLT
ECCCCHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
FSVQSRIQSNIDLIVDKIRTGNVYVNRNQIGAVVGVQPFGGSGLSGTGPKAGGPFYLHRF
EEEHHHHHCCHHHHHHHEECCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
VTEKTVTVNTTALGGNVALACLEEE
HCCCEEEEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]