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The map label for this gene is nuoD

Identifier: 88607271

GI number: 88607271

Start: 776565

End: 777752

Strand: Reverse

Name: nuoD

Synonym: APH_0732

Alternate gene names: 88607271

Gene position: 777752-776565 (Counterclockwise)

Preceding gene: 88606976

Following gene: 88607823

Centisome position: 52.86

GC content: 43.35

Gene sequence:

>1188_bases
ATGTCTGATAGCTCTGATGGCTATGCCAAGCCGATGACCATAAATTTTGGTCCTCAGCATCCGGCGGCGCATGGCGTTAT
GCGTTTGATACTTGAAATGAGTGGAGAGGTTATCGAAAGGATAGACCCTCACATAGGTTTGCTGCATAGGGGGACCGAAA
AGCTCATTGAATATAAGACTTATCTTCAGGCGCTTCCGTATTTTGATAGGTTAGATTATGTGTCTCCTATGTCGCAGGAG
CATGCTTATTCTCTGTGTGTGGAGCGGCTGTTGGGTTGTGAGGTACCGATAAGGGCGAAGTATCTCAGGGTTATTTTTTG
CGAGCTGACTAGACTATTAAATCACTTATTAAATGTGGCATGTCAGGCGTTAGATTCAGGTGCTACTACTCCATTGCTGT
GGATTTTTGAAGAGCGGGAGAAGATACTTTCTTTTTATGAAAGGGCTTCGGGAGCGAGATTTCATTCGGCTTATATTAGG
CCGGGCGGCCTAGCTGCTGATGTACCCGATGGTCTTTTGGACGATATACATGAGTTTACTAACTATTTTCCTAAATTATT
AGATAGTGTTGATGATTTGCTTACGGAGAATAGTATTTGGAAGCAGCGTAACGTTGAAATAGGAAAGGTTACTAAGCAAC
AGGCTCTTGATTGGGGATTTTCCGGGCCAATGCTTAGAGCTTGTGGAATCCCGTGGGATTTACGTAAAAGCCAGCCATAT
GAAATATATGATATATTAGACTTTAAGGTGCCTGTTGGTAGCAATGGAGATTGTTATGACAGGTATCTTGTGCGTATGGC
TGAGATACGTGAATCGCTCTATATACTTGAGCAGTGTCTGCGTGATATACCTAGTGGGCCGGTGAAAACCGATGATAGAA
AGATTGCTCCTCCTAAGAGAGAAGAGTTAAAATACTCAATGGAAGCATTGATTCACCATTTTAAGCTGTTCTCTGAGGGA
TATAAGGTGCCAGAGGGTGAGGCGTATGCTGCTGTAGAAGCTCCTAAGGGTGAATTTGGGGTATATATAGTCTCAGATGG
TACTAATAAACCTTATAGATGCAGGATAAGATCACCGGGGTTTGCTCACTTGCAGGCCATAGATGCTATGGCGCGTGGAC
ACATGCTTGCGGATTTGCCGGTTATTATAGGCTCTTTGGATATTGTTTTTGGTGAAATAGATAGATGA

Upstream 100 bases:

>100_bases
TATAGGGAATTCTCACGTTATCAGGGAAACTGATTGACGAATTAGAACTTGACATCTGCACCTATTATAAGATACTAAAA
CTTGTTCTTTAGTAGCTAAA

Downstream 100 bases:

>100_bases
ACTCTGCAGATCAGGAAAGCTTTAGGTTCACTGATGGTAACCTAGAAGAAGCATATAAGTGCATAAGTAGATATCCTGAA
GGTAGGCAAGCGAGTGCAGT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSDSSDGYAKPMTINFGPQHPAAHGVMRLILEMSGEVIERIDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSPMSQE
HAYSLCVERLLGCEVPIRAKYLRVIFCELTRLLNHLLNVACQALDSGATTPLLWIFEEREKILSFYERASGARFHSAYIR
PGGLAADVPDGLLDDIHEFTNYFPKLLDSVDDLLTENSIWKQRNVEIGKVTKQQALDWGFSGPMLRACGIPWDLRKSQPY
EIYDILDFKVPVGSNGDCYDRYLVRMAEIRESLYILEQCLRDIPSGPVKTDDRKIAPPKREELKYSMEALIHHFKLFSEG
YKVPEGEAYAAVEAPKGEFGVYIVSDGTNKPYRCRIRSPGFAHLQAIDAMARGHMLADLPVIIGSLDIVFGEIDR

Sequences:

>Translated_395_residues
MSDSSDGYAKPMTINFGPQHPAAHGVMRLILEMSGEVIERIDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSPMSQE
HAYSLCVERLLGCEVPIRAKYLRVIFCELTRLLNHLLNVACQALDSGATTPLLWIFEEREKILSFYERASGARFHSAYIR
PGGLAADVPDGLLDDIHEFTNYFPKLLDSVDDLLTENSIWKQRNVEIGKVTKQQALDWGFSGPMLRACGIPWDLRKSQPY
EIYDILDFKVPVGSNGDCYDRYLVRMAEIRESLYILEQCLRDIPSGPVKTDDRKIAPPKREELKYSMEALIHHFKLFSEG
YKVPEGEAYAAVEAPKGEFGVYIVSDGTNKPYRCRIRSPGFAHLQAIDAMARGHMLADLPVIIGSLDIVFGEIDR
>Mature_394_residues
SDSSDGYAKPMTINFGPQHPAAHGVMRLILEMSGEVIERIDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSPMSQEH
AYSLCVERLLGCEVPIRAKYLRVIFCELTRLLNHLLNVACQALDSGATTPLLWIFEEREKILSFYERASGARFHSAYIRP
GGLAADVPDGLLDDIHEFTNYFPKLLDSVDDLLTENSIWKQRNVEIGKVTKQQALDWGFSGPMLRACGIPWDLRKSQPYE
IYDILDFKVPVGSNGDCYDRYLVRMAEIRESLYILEQCLRDIPSGPVKTDDRKIAPPKREELKYSMEALIHHFKLFSEGY
KVPEGEAYAAVEAPKGEFGVYIVSDGTNKPYRCRIRSPGFAHLQAIDAMARGHMLADLPVIIGSLDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=391, Percent_Identity=63.6828644501279, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI260898743, Length=385, Percent_Identity=63.1168831168831, Blast_Score=527, Evalue=1e-150,
Organism=Escherichia coli, GI145693162, Length=385, Percent_Identity=41.5584415584416, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1789076, Length=391, Percent_Identity=27.3657289002558, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1788832, Length=393, Percent_Identity=26.972010178117, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17555284, Length=400, Percent_Identity=58.25, Blast_Score=514, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17568379, Length=400, Percent_Identity=58, Blast_Score=514, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24638644, Length=386, Percent_Identity=63.9896373056995, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI221459469, Length=382, Percent_Identity=61.5183246073298, Blast_Score=513, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_ANAPZ (Q2GJY9)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505312.1
- HSSP:   Q56220
- ProteinModelPortal:   Q2GJY9
- SMR:   Q2GJY9
- STRING:   Q2GJY9
- GeneID:   3930545
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0732
- NMPDR:   fig|212042.5.peg.714
- TIGR:   APH_0732
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   MADVITI
- PhylomeDB:   Q2GJY9
- ProtClustDB:   PRK06075
- BioCyc:   APHA212042:APH_0732-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 44822; Mature: 44691

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00535 COMPLEX1_49K; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSSDGYAKPMTINFGPQHPAAHGVMRLILEMSGEVIERIDPHIGLLHRGTEKLIEYKT
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YLQALPYFDRLDYVSPMSQEHAYSLCVERLLGCEVPIRAKYLRVIFCELTRLLNHLLNVA
HHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CQALDSGATTPLLWIFEEREKILSFYERASGARFHSAYIRPGGLAADVPDGLLDDIHEFT
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCEEHEEEECCCCCCCCCCCHHHHHHHHHH
NYFPKLLDSVDDLLTENSIWKQRNVEIGKVTKQQALDWGFSGPMLRACGIPWDLRKSQPY
HHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
EIYDILDFKVPVGSNGDCYDRYLVRMAEIRESLYILEQCLRDIPSGPVKTDDRKIAPPKR
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
EELKYSMEALIHHFKLFSEGYKVPEGEAYAAVEAPKGEFGVYIVSDGTNKPYRCRIRSPG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCC
FAHLQAIDAMARGHMLADLPVIIGSLDIVFGEIDR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
SDSSDGYAKPMTINFGPQHPAAHGVMRLILEMSGEVIERIDPHIGLLHRGTEKLIEYKT
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YLQALPYFDRLDYVSPMSQEHAYSLCVERLLGCEVPIRAKYLRVIFCELTRLLNHLLNVA
HHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CQALDSGATTPLLWIFEEREKILSFYERASGARFHSAYIRPGGLAADVPDGLLDDIHEFT
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCEEHEEEECCCCCCCCCCCHHHHHHHHHH
NYFPKLLDSVDDLLTENSIWKQRNVEIGKVTKQQALDWGFSGPMLRACGIPWDLRKSQPY
HHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
EIYDILDFKVPVGSNGDCYDRYLVRMAEIRESLYILEQCLRDIPSGPVKTDDRKIAPPKR
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
EELKYSMEALIHHFKLFSEGYKVPEGEAYAAVEAPKGEFGVYIVSDGTNKPYRCRIRSPG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCC
FAHLQAIDAMARGHMLADLPVIIGSLDIVFGEIDR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA