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The map label for this gene is infC [H]

Identifier: 88607227

GI number: 88607227

Start: 1332034

End: 1332552

Strand: Reverse

Name: infC [H]

Synonym: APH_1263

Alternate gene names: 88607227

Gene position: 1332552-1332034 (Counterclockwise)

Preceding gene: 88607718

Following gene: 88607891

Centisome position: 90.57

GC content: 42.39

Gene sequence:

>519_bases
GTGGATAAAAAAGGTCCTAGAATAAACGATGCTATCACTACGAAGAGGGTTCGTCTCGTTGACGAGACTGGAACTATGGT
TGGGGTAGTAGACATAGAAGAGGCTTTGGCTGTTGCAGCTCGTGCTGGTATGGACTTGGTTGAAGTTGTCAGTGAGGGCG
AGTATCCAGTTTGCAAGGTATACAACTACAGTAAGCAAAAGTACAACAAGAAAAAGCATGGTGTAACGAAAAAGCAGAGG
TCTTCTGCTGTCAAGGAGCTTAAGTTCAGGATAAACATTGAGGACAATGACTACAATATCAAGTTGAACAATTTGAAATC
CTTCATAGAGAAGGGAAATAAGGTCAAAGTTTCTCTGAGGTTTGTGGGTCGTGAGCTACAGTATAAAGAGGTAGGTCTTG
ATATATTGGATCGCCTTGTTAGTGATACAGAGGGGATTGCTAAGCCAGAATCTTCACCAAGAATGGATGGTAATGTCCTG
AGTATGATGTTTGGCGCTAAAACTGGTGGTGGGTCTTAA

Upstream 100 bases:

>100_bases
AGCAATGCGTGTAGCATGGAGGCTGATAAAGCGTTGAAAACGTTAGTGACTTATGTTAGCATCCGTCAGGTGCTTTAGTG
TTTAGGTAAGTGGGTTAAAA

Downstream 100 bases:

>100_bases
TCGTCTTCTCTAAGAGCAGCTTGTCTCCTTTGTTCACATGTTTCATTCTGTAAGGATATAGGCATGTAGGTCTCTCGTGC
TTGTGTCACAGTGTGATGTG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MDKKGPRINDAITTKRVRLVDETGTMVGVVDIEEALAVAARAGMDLVEVVSEGEYPVCKVYNYSKQKYNKKKHGVTKKQR
SSAVKELKFRINIEDNDYNIKLNNLKSFIEKGNKVKVSLRFVGRELQYKEVGLDILDRLVSDTEGIAKPESSPRMDGNVL
SMMFGAKTGGGS

Sequences:

>Translated_172_residues
MDKKGPRINDAITTKRVRLVDETGTMVGVVDIEEALAVAARAGMDLVEVVSEGEYPVCKVYNYSKQKYNKKKHGVTKKQR
SSAVKELKFRINIEDNDYNIKLNNLKSFIEKGNKVKVSLRFVGRELQYKEVGLDILDRLVSDTEGIAKPESSPRMDGNVL
SMMFGAKTGGGS
>Mature_172_residues
MDKKGPRINDAITTKRVRLVDETGTMVGVVDIEEALAVAARAGMDLVEVVSEGEYPVCKVYNYSKQKYNKKKHGVTKKQR
SSAVKELKFRINIEDNDYNIKLNNLKSFIEKGNKVKVSLRFVGRELQYKEVGLDILDRLVSDTEGIAKPESSPRMDGNVL
SMMFGAKTGGGS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=38.4146341463415, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19146; Mature: 19146

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKGPRINDAITTKRVRLVDETGTMVGVVDIEEALAVAARAGMDLVEVVSEGEYPVCKV
CCCCCCCCCHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHCCCHHHHHHHCCCCCEEEE
YNYSKQKYNKKKHGVTKKQRSSAVKELKFRINIEDNDYNIKLNNLKSFIEKGNKVKVSLR
ECCHHHHHCHHHCCCCHHHHHHHHHHEEEEEEEECCCEEEEHHHHHHHHHCCCEEEEEEE
FVGRELQYKEVGLDILDRLVSDTEGIAKPESSPRMDGNVLSMMFGAKTGGGS
EECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDKKGPRINDAITTKRVRLVDETGTMVGVVDIEEALAVAARAGMDLVEVVSEGEYPVCKV
CCCCCCCCCHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHCCCHHHHHHHCCCCCEEEE
YNYSKQKYNKKKHGVTKKQRSSAVKELKFRINIEDNDYNIKLNNLKSFIEKGNKVKVSLR
ECCHHHHHCHHHCCCCHHHHHHHHHHEEEEEEEECCCEEEEHHHHHHHHHCCCEEEEEEE
FVGRELQYKEVGLDILDRLVSDTEGIAKPESSPRMDGNVLSMMFGAKTGGGS
EECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA