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The map label for this gene is argS

Identifier: 88607168

GI number: 88607168

Start: 722086

End: 723828

Strand: Direct

Name: argS

Synonym: APH_0700

Alternate gene names: 88607168

Gene position: 722086-723828 (Clockwise)

Preceding gene: 88607076

Following gene: 88606836

Centisome position: 49.08

GC content: 38.96

Gene sequence:

>1743_bases
ATGTTATTAGATGATAAAATATTGGATATCTTTGGCTTTTTCCGGAATGCAATAGAAGAGCGAATAAGGGCTGTGTGGTC
AGGAGATAACATTCCTGAATCATTATTTAAGAGGATTATAGTTGGTCCTCCGGCGCAGCCAAAACATGGGGATTTATATA
CAAATGCAGCACTAATTCTTGGAAAATTTGATAAGAAAAATCCCATGGAATTGGCAAGTACTTTATGTAATGCCTTTGAA
AATATCGAGGGTATAGAAAGTATAAATGTTGTTGCTCCAGGATTCATAAACTTTCACTGTGTAAATAGCGTCTGGCATGG
AGTTGTAAGGAATATAAACAAGCTAGGCAGAGAATATGGACGTACAGATTTAGGTCATAATAAAAAAGTTAATATAGAAT
TCGTTTCAGCAAATCCTACAGGACCGCTACATATAGGACATGCTAGGGGTGCAGTTTTTGGTGATGTTTTGTCTAATCTC
CTTAAGTGGGTAGGTTATGATGTAATAAAAGAGTATTACGTGAATGATGCTGGGTCTCAAGTAAAGACGTTGGTATCCTC
GGTTTTTCTTAGATATAAAGAAGCATTGGGGGAAGAAATCACAATAGGTGCAGGTTTATATCCCGGAGAATATCTAAAGC
CCATAGCGCGGGATTTGGTTGAGAAATACGGCTCTGATCTACTAAACGCTAGTGACAAAGATGAGATAATTAGGAGTTTT
ACTCTGAGTAGCATGCTTAACTTAATTAAGGAAGATTTGGCCCTTTTAGGAGTTGAGCATGATGTATTTGTTTCGGAAAG
TGACTTACAGAACCGTAATGTTATTGAGGAATGTGTAAAGTACCTGCGTGAGCGCGGTATTATATATGAGGGAGTGCTTG
AAAAACCTAAGAGGGAAGATGAGTTAAGCGAATGGCAACCTCGTGTTCAGATGCTGTTTAAGTCAACGGAATTTGGAGAT
GATTCTGATAGAGCTTTGCAAAAGGAAGACGGTACTTGGTCGTATTTTGCTGGTGACATTGGATACCATTTTCACAAGAT
TTCCCGAGGATTTGACTCCATGATAATGACATTGGGGTTCGATCATAAAGGCTATGTTTCAAGACTAAAAGCCGCAGTTG
CTGCGTTAAGTAATGGCAAGGCATCTATAGATATTAAGCTTTATAATTTGGTGAATTTCTTAGAAAATGGCACGCCTGTC
AAAATGTCAAAAAGGAAAGGGGAGTTCCTAACAGTTCGAGATGTAATTGATGAAGTGGGAAGAGATGTTGCGAGATTCAT
GATGCTTACGCGCCGGAATGACGTGGTTTTAGATTTTGATTTCGCTAAAGCTCGAGAAGAATCAAAAGATAGCCAGATAT
TCTATATCCAATATGCACACGCTAGAATACGTTCTATAGTACGGCGTTGTCCTGAGTTATTAGCAATAGAAAAAATAGAT
TTTTCGTGTGTTATTACTGAGCAAGAGCTTTCTTTGCTAAGACTATTGTCAAGATGGCCCAGTGTTATCAAAACGTCAGC
TGAGAATTATGAGCCTCATACAATAGCATTTTACCTGATAGAAGTAGCGGAAGCGTTTCATGCACTTTGGGGCTGCGGCA
ATAGTGATCCTAGTATGAGATTCATAGTAGAGGGTGATCTACATACCACTTCGGCCCGTATTTATATAGCAATAGCCGTA
TCCCATGTTATAGCGTCTGGTCTGGATATTTTTTCCATCACACCTTCGGAAGAAATGAGGTAG

Upstream 100 bases:

>100_bases
TTAGTCTAAAACTGGAGATAATACGTCTATATATATTTGTCTGCTTCTATAGAATAGGAAATCCATATATACAGCAGGTG
CAGTTAGTGGAGTAAATAGC

Downstream 100 bases:

>100_bases
TAAGCGCAAAAAAAACACAAGGTTCTGTTATGTGTATCCGTCTTGATTCTAAAACTAGTCAGGCACTGCTTATGATTATG
GATAGAGGTGTTATATTTTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MLLDDKILDIFGFFRNAIEERIRAVWSGDNIPESLFKRIIVGPPAQPKHGDLYTNAALILGKFDKKNPMELASTLCNAFE
NIEGIESINVVAPGFINFHCVNSVWHGVVRNINKLGREYGRTDLGHNKKVNIEFVSANPTGPLHIGHARGAVFGDVLSNL
LKWVGYDVIKEYYVNDAGSQVKTLVSSVFLRYKEALGEEITIGAGLYPGEYLKPIARDLVEKYGSDLLNASDKDEIIRSF
TLSSMLNLIKEDLALLGVEHDVFVSESDLQNRNVIEECVKYLRERGIIYEGVLEKPKREDELSEWQPRVQMLFKSTEFGD
DSDRALQKEDGTWSYFAGDIGYHFHKISRGFDSMIMTLGFDHKGYVSRLKAAVAALSNGKASIDIKLYNLVNFLENGTPV
KMSKRKGEFLTVRDVIDEVGRDVARFMMLTRRNDVVLDFDFAKAREESKDSQIFYIQYAHARIRSIVRRCPELLAIEKID
FSCVITEQELSLLRLLSRWPSVIKTSAENYEPHTIAFYLIEVAEAFHALWGCGNSDPSMRFIVEGDLHTTSARIYIAIAV
SHVIASGLDIFSITPSEEMR

Sequences:

>Translated_580_residues
MLLDDKILDIFGFFRNAIEERIRAVWSGDNIPESLFKRIIVGPPAQPKHGDLYTNAALILGKFDKKNPMELASTLCNAFE
NIEGIESINVVAPGFINFHCVNSVWHGVVRNINKLGREYGRTDLGHNKKVNIEFVSANPTGPLHIGHARGAVFGDVLSNL
LKWVGYDVIKEYYVNDAGSQVKTLVSSVFLRYKEALGEEITIGAGLYPGEYLKPIARDLVEKYGSDLLNASDKDEIIRSF
TLSSMLNLIKEDLALLGVEHDVFVSESDLQNRNVIEECVKYLRERGIIYEGVLEKPKREDELSEWQPRVQMLFKSTEFGD
DSDRALQKEDGTWSYFAGDIGYHFHKISRGFDSMIMTLGFDHKGYVSRLKAAVAALSNGKASIDIKLYNLVNFLENGTPV
KMSKRKGEFLTVRDVIDEVGRDVARFMMLTRRNDVVLDFDFAKAREESKDSQIFYIQYAHARIRSIVRRCPELLAIEKID
FSCVITEQELSLLRLLSRWPSVIKTSAENYEPHTIAFYLIEVAEAFHALWGCGNSDPSMRFIVEGDLHTTSARIYIAIAV
SHVIASGLDIFSITPSEEMR
>Mature_580_residues
MLLDDKILDIFGFFRNAIEERIRAVWSGDNIPESLFKRIIVGPPAQPKHGDLYTNAALILGKFDKKNPMELASTLCNAFE
NIEGIESINVVAPGFINFHCVNSVWHGVVRNINKLGREYGRTDLGHNKKVNIEFVSANPTGPLHIGHARGAVFGDVLSNL
LKWVGYDVIKEYYVNDAGSQVKTLVSSVFLRYKEALGEEITIGAGLYPGEYLKPIARDLVEKYGSDLLNASDKDEIIRSF
TLSSMLNLIKEDLALLGVEHDVFVSESDLQNRNVIEECVKYLRERGIIYEGVLEKPKREDELSEWQPRVQMLFKSTEFGD
DSDRALQKEDGTWSYFAGDIGYHFHKISRGFDSMIMTLGFDHKGYVSRLKAAVAALSNGKASIDIKLYNLVNFLENGTPV
KMSKRKGEFLTVRDVIDEVGRDVARFMMLTRRNDVVLDFDFAKAREESKDSQIFYIQYAHARIRSIVRRCPELLAIEKID
FSCVITEQELSLLRLLSRWPSVIKTSAENYEPHTIAFYLIEVAEAFHALWGCGNSDPSMRFIVEGDLHTTSARIYIAIAV
SHVIASGLDIFSITPSEEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=170, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1788184, Length=590, Percent_Identity=21.0169491525424, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71985061, Length=193, Percent_Identity=25.9067357512953, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985068, Length=193, Percent_Identity=25.9067357512953, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320548, Length=559, Percent_Identity=24.1502683363148, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ANAPZ (Q2GK20)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505281.1
- ProteinModelPortal:   Q2GK20
- STRING:   Q2GK20
- GeneID:   3930454
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0700
- NMPDR:   fig|212042.5.peg.681
- TIGR:   APH_0700
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   ETIRGCL
- ProtClustDB:   PRK01611
- BioCyc:   APHA212042:APH_0700-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65546; Mature: 65546

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDDKILDIFGFFRNAIEERIRAVWSGDNIPESLFKRIIVGPPAQPKHGDLYTNAALIL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHCHHHEE
GKFDKKNPMELASTLCNAFENIEGIESINVVAPGFINFHCVNSVWHGVVRNINKLGREYG
ECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
RTDLGHNKKVNIEFVSANPTGPLHIGHARGAVFGDVLSNLLKWVGYDVIKEYYVNDAGSQ
CCCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VKTLVSSVFLRYKEALGEEITIGAGLYPGEYLKPIARDLVEKYGSDLLNASDKDEIIRSF
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHH
TLSSMLNLIKEDLALLGVEHDVFVSESDLQNRNVIEECVKYLRERGIIYEGVLEKPKRED
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHCCCCCCC
ELSEWQPRVQMLFKSTEFGDDSDRALQKEDGTWSYFAGDIGYHFHKISRGFDSMIMTLGF
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
DHKGYVSRLKAAVAALSNGKASIDIKLYNLVNFLENGTPVKMSKRKGEFLTVRDVIDEVG
CCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCEEEECCCCCEEEHHHHHHHHH
RDVARFMMLTRRNDVVLDFDFAKAREESKDSQIFYIQYAHARIRSIVRRCPELLAIEKID
HHHHHHHHHHCCCCEEEEECHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCHHHHHHHCCC
FSCVITEQELSLLRLLSRWPSVIKTSAENYEPHTIAFYLIEVAEAFHALWGCGNSDPSMR
EEEEEEHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FIVEGDLHTTSARIYIAIAVSHVIASGLDIFSITPSEEMR
EEEECCCEECCCEEEEHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MLLDDKILDIFGFFRNAIEERIRAVWSGDNIPESLFKRIIVGPPAQPKHGDLYTNAALIL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHCHHHEE
GKFDKKNPMELASTLCNAFENIEGIESINVVAPGFINFHCVNSVWHGVVRNINKLGREYG
ECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
RTDLGHNKKVNIEFVSANPTGPLHIGHARGAVFGDVLSNLLKWVGYDVIKEYYVNDAGSQ
CCCCCCCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VKTLVSSVFLRYKEALGEEITIGAGLYPGEYLKPIARDLVEKYGSDLLNASDKDEIIRSF
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHH
TLSSMLNLIKEDLALLGVEHDVFVSESDLQNRNVIEECVKYLRERGIIYEGVLEKPKRED
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHCCCCCCC
ELSEWQPRVQMLFKSTEFGDDSDRALQKEDGTWSYFAGDIGYHFHKISRGFDSMIMTLGF
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCC
DHKGYVSRLKAAVAALSNGKASIDIKLYNLVNFLENGTPVKMSKRKGEFLTVRDVIDEVG
CCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCEEEECCCCCEEEHHHHHHHHH
RDVARFMMLTRRNDVVLDFDFAKAREESKDSQIFYIQYAHARIRSIVRRCPELLAIEKID
HHHHHHHHHHCCCCEEEEECHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCHHHHHHHCCC
FSCVITEQELSLLRLLSRWPSVIKTSAENYEPHTIAFYLIEVAEAFHALWGCGNSDPSMR
EEEEEEHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FIVEGDLHTTSARIYIAIAVSHVIASGLDIFSITPSEEMR
EEEECCCEECCCEEEEHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA