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The map label for this gene is ftsK [H]

Identifier: 88606818

GI number: 88606818

Start: 1016456

End: 1018963

Strand: Reverse

Name: ftsK [H]

Synonym: APH_0955

Alternate gene names: 88606818

Gene position: 1018963-1016456 (Counterclockwise)

Preceding gene: 88606991

Following gene: 88607686

Centisome position: 69.26

GC content: 42.9

Gene sequence:

>2508_bases
ATGGCAGGCGTTGTACCTGGGATTTTAACGTTGGCGTGGTTACAAAAACTGCCTAAATTCGTGCGTAGAATATACATACC
AGCTCTATGTCTTGTTACTTTTAGCATTGCGGGAATACTGGCAAAGTTTTCATTTAAAGCTACAAGCGTGTTCCATTATG
GGGGTTTTGTAGGGCAAAAATTTGAAAGTTTTTCTTTAATTACGTTGATTGTATCGGCTTCTATAGGCATTTTTAGCTCT
ATAGGGTGGCAAGTGCCTGTATTTTTCGCTAGGATTCTGGTCAAATTGCTATCTCGCTTGAGATTGAGGGTGAGTGCAGG
CAGACTTAAAGAAAATGAAAGCAATAATGTTTCAGAGATTACCGTGCCGACGAGCTATGTCATGCATGGTGTAAACACTG
CCGGGGAGGGGACATCTCCGCTGAAGGATCATGCGTTGAATATTGTTCAAGATGATGATGTACGAGAGCATATCGCAGTA
GAACATGGGCAACATAGGGAGTACGCGAATACGAAGATCATTAACACATTTGCTCCTTCTGGGCATTATGGATACGAGGA
GAAGTTCCATGGTGTTCCTGAGCAGGAAGATAGTGTCATCGAAGAGCAATATGAGAAAGATCAGGATGAGTTTTTTGATG
AGGAAGAGGAATTTGATGATTGTGAGTTAGATGACTCTTTTGAAGAAGACTGTGAAGATGATATGGAAGATAGTCCACTT
CATGATGAACCTAGATACGAAGCATCCTCAACGCGTTGTGGTGATGTAGATATTGCAGGAGAGGACGAAGAGGATGTTGC
TCTCTGCCAAGATGAAGAAGAATACGACGAGGACGATTGGGATATAGATGATAAAGAAGAGGATGAGGAGTGTGAGATAG
AGGAAGGTTCTTCTTCTCTTAATGCTTTGGAACCAGATGAGGATGATGCTCTAGAAGAAGAGTATGAGGAAGAAGAGTAT
GAGGAAGAAGAGGGGTATGAAGAAGATGATGATGCATCGTACAACCAGGAGGAGGTACGAAATTTCACCTTGCCTCATGT
AGAGCTATTGGAGGATAGGCGAGAGCATGCGCAGGATGACGTGGATGATAGCGCATATAAAAATGAATCTGAGGAGTTGT
ACGAGGTTCTCAAAGATTTTGGCGTATATGGCAAGATCATAGATGTTCGCTATGGACCAGTAGTGACTCTATACGAGTTT
GAGCCTTCAGCAGGAACGAAGTCTTCGCGAATTATAGGCTTATCAGATGATATAGCGCGGTCTATGAGTGCGCTATCGAC
CAGGATTTCAGTTGTCCCTGGTAGAAATGTTATGGGCATTGAATTGCCGAATCGCAATAGAAAGATGGTGGTGCTTCGTG
ATCTGATAGAAAGCAAGGAATATTTGGACCGTGCTCTGAAGTTACCTATCATTTTAGGTAAAGGTATAGATGGCGAGCCT
GTAGTAGGTGATTTGACGAAAATGCCCCATCTGTTAATCGCAGGTACAACGGGTTCAGGAAAGTCGGTTGGTATAAATAC
CATGATTCTGTCATTATTGTATAGGCTCACGCCTGATCAGTGTAGAATGATAATGATAGACCCAAAAGTATTGGAGTTGT
CAGTTTACGATAATATTCCGCACTTATTGACTCCTGTGGTGACTGAAGCGAAAAAAGCAGTAGCAGTGCTAAAGTGGGTG
GTAGCGGAGATGGAAGAGCGCTACAGGTTGATGTCGGCAGTAGGTGTGAGGAACATCACGGGGTATAATGAGAAGATTGC
TGAGGCGGCATGCTGTGGTGAAGTTTTTAAGCGTACTGTGCAGACGGGTTACGATAAGGATTCAGGAGAACCTATTTTTG
AGCAGGAAAAGATCAAAAATATCACTCTTCCATACATTGTAGTTATTGTCGACGAAATGGCAGACTTGATGATAGTTTCC
GGCAAGGAGATAGAGTCATCAATTCAGAGATTGTCTCAAATGGCTAGGGCTGCGGGTATACACATTATTATGGCGACGCA
GAGGCCTTCTGTAGATGTTATTACAGGTGTTATAAAGGCTAATTTTCCCACTAGGATAAGCTTTTCTGTAACTTCTCGAG
TTGATAGTAGAACAATTTTGGGAGAACAAGGCGCGGAGCAACTGCTCGGGATGGGGGATATGCTATACATGGTTGCAGGG
GGTAAAATACGTCGCATTCACGGTGCTTTTGTTAGTGATAATGAAGTTCAAGATGTTGTGAATCATTTGCGTATGCAGTG
CAAGCCCAGATATGTAGAAGGTATTGCTAGGGCCTTAGATAGCAGTGTAGGGGATGAAATATCTACAGAAAATTTCGATG
GTAAAGATGATGCCTTATATGAAAAAGCAGTTTCTGTTGTGCTAAGAGATAGAAAGACGTCGGTTAGTTATGTGCAGCGA
CAATTGCGCATCGGGTATAACAGAGCTGCGAATATAGTGGAAAGAATGGAGCGTGAAGGCATAATAACTGAGGTAGGGCA
CCTAGGCAAAAGAGAGATAGTGGATTAG

Upstream 100 bases:

>100_bases
AAACTCTACAGGATGTATTGGCACTGCTGCTGGAGAGGTAAGCAATTTGATGGGAACTGCAGGAGCATATCTCGCTGACG
TTCTCGTGCAACTTTTTGGG

Downstream 100 bases:

>100_bases
TATGAACATCTGCCATAAAAATGGTAATAGACGGCTATAGCTGCTCAGTCTAAGCCCAATAGCATTATGCGTTCTAGCCC
ACTAAAGCATGGTGCACGGG

Product: FtsK/SpoIIIE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MAGVVPGILTLAWLQKLPKFVRRIYIPALCLVTFSIAGILAKFSFKATSVFHYGGFVGQKFESFSLITLIVSASIGIFSS
IGWQVPVFFARILVKLLSRLRLRVSAGRLKENESNNVSEITVPTSYVMHGVNTAGEGTSPLKDHALNIVQDDDVREHIAV
EHGQHREYANTKIINTFAPSGHYGYEEKFHGVPEQEDSVIEEQYEKDQDEFFDEEEEFDDCELDDSFEEDCEDDMEDSPL
HDEPRYEASSTRCGDVDIAGEDEEDVALCQDEEEYDEDDWDIDDKEEDEECEIEEGSSSLNALEPDEDDALEEEYEEEEY
EEEEGYEEDDDASYNQEEVRNFTLPHVELLEDRREHAQDDVDDSAYKNESEELYEVLKDFGVYGKIIDVRYGPVVTLYEF
EPSAGTKSSRIIGLSDDIARSMSALSTRISVVPGRNVMGIELPNRNRKMVVLRDLIESKEYLDRALKLPIILGKGIDGEP
VVGDLTKMPHLLIAGTTGSGKSVGINTMILSLLYRLTPDQCRMIMIDPKVLELSVYDNIPHLLTPVVTEAKKAVAVLKWV
VAEMEERYRLMSAVGVRNITGYNEKIAEAACCGEVFKRTVQTGYDKDSGEPIFEQEKIKNITLPYIVVIVDEMADLMIVS
GKEIESSIQRLSQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFSVTSRVDSRTILGEQGAEQLLGMGDMLYMVAG
GKIRRIHGAFVSDNEVQDVVNHLRMQCKPRYVEGIARALDSSVGDEISTENFDGKDDALYEKAVSVVLRDRKTSVSYVQR
QLRIGYNRAANIVERMEREGIITEVGHLGKREIVD

Sequences:

>Translated_835_residues
MAGVVPGILTLAWLQKLPKFVRRIYIPALCLVTFSIAGILAKFSFKATSVFHYGGFVGQKFESFSLITLIVSASIGIFSS
IGWQVPVFFARILVKLLSRLRLRVSAGRLKENESNNVSEITVPTSYVMHGVNTAGEGTSPLKDHALNIVQDDDVREHIAV
EHGQHREYANTKIINTFAPSGHYGYEEKFHGVPEQEDSVIEEQYEKDQDEFFDEEEEFDDCELDDSFEEDCEDDMEDSPL
HDEPRYEASSTRCGDVDIAGEDEEDVALCQDEEEYDEDDWDIDDKEEDEECEIEEGSSSLNALEPDEDDALEEEYEEEEY
EEEEGYEEDDDASYNQEEVRNFTLPHVELLEDRREHAQDDVDDSAYKNESEELYEVLKDFGVYGKIIDVRYGPVVTLYEF
EPSAGTKSSRIIGLSDDIARSMSALSTRISVVPGRNVMGIELPNRNRKMVVLRDLIESKEYLDRALKLPIILGKGIDGEP
VVGDLTKMPHLLIAGTTGSGKSVGINTMILSLLYRLTPDQCRMIMIDPKVLELSVYDNIPHLLTPVVTEAKKAVAVLKWV
VAEMEERYRLMSAVGVRNITGYNEKIAEAACCGEVFKRTVQTGYDKDSGEPIFEQEKIKNITLPYIVVIVDEMADLMIVS
GKEIESSIQRLSQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFSVTSRVDSRTILGEQGAEQLLGMGDMLYMVAG
GKIRRIHGAFVSDNEVQDVVNHLRMQCKPRYVEGIARALDSSVGDEISTENFDGKDDALYEKAVSVVLRDRKTSVSYVQR
QLRIGYNRAANIVERMEREGIITEVGHLGKREIVD
>Mature_834_residues
AGVVPGILTLAWLQKLPKFVRRIYIPALCLVTFSIAGILAKFSFKATSVFHYGGFVGQKFESFSLITLIVSASIGIFSSI
GWQVPVFFARILVKLLSRLRLRVSAGRLKENESNNVSEITVPTSYVMHGVNTAGEGTSPLKDHALNIVQDDDVREHIAVE
HGQHREYANTKIINTFAPSGHYGYEEKFHGVPEQEDSVIEEQYEKDQDEFFDEEEEFDDCELDDSFEEDCEDDMEDSPLH
DEPRYEASSTRCGDVDIAGEDEEDVALCQDEEEYDEDDWDIDDKEEDEECEIEEGSSSLNALEPDEDDALEEEYEEEEYE
EEEGYEEDDDASYNQEEVRNFTLPHVELLEDRREHAQDDVDDSAYKNESEELYEVLKDFGVYGKIIDVRYGPVVTLYEFE
PSAGTKSSRIIGLSDDIARSMSALSTRISVVPGRNVMGIELPNRNRKMVVLRDLIESKEYLDRALKLPIILGKGIDGEPV
VGDLTKMPHLLIAGTTGSGKSVGINTMILSLLYRLTPDQCRMIMIDPKVLELSVYDNIPHLLTPVVTEAKKAVAVLKWVV
AEMEERYRLMSAVGVRNITGYNEKIAEAACCGEVFKRTVQTGYDKDSGEPIFEQEKIKNITLPYIVVIVDEMADLMIVSG
KEIESSIQRLSQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFSVTSRVDSRTILGEQGAEQLLGMGDMLYMVAGG
KIRRIHGAFVSDNEVQDVVNHLRMQCKPRYVEGIARALDSSVGDEISTENFDGKDDALYEKAVSVVLRDRKTSVSYVQRQ
LRIGYNRAANIVERMEREGIITEVGHLGKREIVD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=500, Percent_Identity=50.6, Blast_Score=484, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 93854; Mature: 93723

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVVPGILTLAWLQKLPKFVRRIYIPALCLVTFSIAGILAKFSFKATSVFHYGGFVGQK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCHHHCC
FESFSLITLIVSASIGIFSSIGWQVPVFFARILVKLLSRLRLRVSAGRLKENESNNVSEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TVPTSYVMHGVNTAGEGTSPLKDHALNIVQDDDVREHIAVEHGQHREYANTKIINTFAPS
ECCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECCCC
GHYGYEEKFHGVPEQEDSVIEEQYEKDQDEFFDEEEEFDDCELDDSFEEDCEDDMEDSPL
CCCCCHHHHCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
HDEPRYEASSTRCGDVDIAGEDEEDVALCQDEEEYDEDDWDIDDKEEDEECEIEEGSSSL
CCCCCCCCCCCCCCCEEECCCCCCCCEECCCCHHCCCCCCCCCCCCCCCCCCHHCCCCCC
NALEPDEDDALEEEYEEEEYEEEEGYEEDDDASYNQEEVRNFTLPHVELLEDRREHAQDD
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCC
VDDSAYKNESEELYEVLKDFGVYGKIIDVRYGPVVTLYEFEPSAGTKSSRIIGLSDDIAR
CCHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCEEEECCHHHHH
SMSALSTRISVVPGRNVMGIELPNRNRKMVVLRDLIESKEYLDRALKLPIILGKGIDGEP
HHHHHHHHEEEECCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
VVGDLTKMPHLLIAGTTGSGKSVGINTMILSLLYRLTPDQCRMIMIDPKVLELSVYDNIP
CCCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCH
HLLTPVVTEAKKAVAVLKWVVAEMEERYRLMSAVGVRNITGYNEKIAEAACCGEVFKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QTGYDKDSGEPIFEQEKIKNITLPYIVVIVDEMADLMIVSGKEIESSIQRLSQMARAAGI
HCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCE
HIIMATQRPSVDVITGVIKANFPTRISFSVTSRVDSRTILGEQGAEQLLGMGDMLYMVAG
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEHHCCCCHHHHCHHHHHHHHCCCCEEEEECC
GKIRRIHGAFVSDNEVQDVVNHLRMQCKPRYVEGIARALDSSVGDEISTENFDGKDDALY
CEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EKAVSVVLRDRKTSVSYVQRQLRIGYNRAANIVERMEREGIITEVGHLGKREIVD
HHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHCCCCHHCCC
>Mature Secondary Structure 
AGVVPGILTLAWLQKLPKFVRRIYIPALCLVTFSIAGILAKFSFKATSVFHYGGFVGQK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCHHHCC
FESFSLITLIVSASIGIFSSIGWQVPVFFARILVKLLSRLRLRVSAGRLKENESNNVSEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TVPTSYVMHGVNTAGEGTSPLKDHALNIVQDDDVREHIAVEHGQHREYANTKIINTFAPS
ECCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECCCC
GHYGYEEKFHGVPEQEDSVIEEQYEKDQDEFFDEEEEFDDCELDDSFEEDCEDDMEDSPL
CCCCCHHHHCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
HDEPRYEASSTRCGDVDIAGEDEEDVALCQDEEEYDEDDWDIDDKEEDEECEIEEGSSSL
CCCCCCCCCCCCCCCEEECCCCCCCCEECCCCHHCCCCCCCCCCCCCCCCCCHHCCCCCC
NALEPDEDDALEEEYEEEEYEEEEGYEEDDDASYNQEEVRNFTLPHVELLEDRREHAQDD
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCC
VDDSAYKNESEELYEVLKDFGVYGKIIDVRYGPVVTLYEFEPSAGTKSSRIIGLSDDIAR
CCHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCEEEECCHHHHH
SMSALSTRISVVPGRNVMGIELPNRNRKMVVLRDLIESKEYLDRALKLPIILGKGIDGEP
HHHHHHHHEEEECCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
VVGDLTKMPHLLIAGTTGSGKSVGINTMILSLLYRLTPDQCRMIMIDPKVLELSVYDNIP
CCCHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCH
HLLTPVVTEAKKAVAVLKWVVAEMEERYRLMSAVGVRNITGYNEKIAEAACCGEVFKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QTGYDKDSGEPIFEQEKIKNITLPYIVVIVDEMADLMIVSGKEIESSIQRLSQMARAAGI
HCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCE
HIIMATQRPSVDVITGVIKANFPTRISFSVTSRVDSRTILGEQGAEQLLGMGDMLYMVAG
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEHHCCCCHHHHCHHHHHHHHCCCCEEEEECC
GKIRRIHGAFVSDNEVQDVVNHLRMQCKPRYVEGIARALDSSVGDEISTENFDGKDDALY
CEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EKAVSVVLRDRKTSVSYVQRQLRIGYNRAANIVERMEREGIITEVGHLGKREIVD
HHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]